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All Journal Jurnal Sain Veteriner Jurnal Veteriner Journal of Food and Life Sciences Journal of Innovation and Applied Technology Jurnal Ternak Tropika Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Medik Veteriner Vitek : Bidang Kedokteran Hewan Veterinary Biomedical and Clinical Journal Jurnal Nutrisi Ternak Tropis (JNT) Jurnal Pengabdian Masyarakat Asia Rambideun : Jurnal Pengabdian Kepada Masyarakat Prosiding Seminar Nasional Unimus
Yudit Oktanella, Yudit
Departement Of Veterinary Reproduction, Veterinary Medicine Faculty, Brawijaya University, Puncak Dieng, Dau, Malang, East Java 65151, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Veterinary Biomedical and Clinical Journal

 1 
The Effect of Triponyl Sulphate on Fetuses Development and Placental Abnormalities in Inducing Preeclampsia of Rattus norvegicus animal model Purwatiningsih, Wawid; Aryani, Dhita Evi; Vidiastuti, Dian; Oktanella, Yudit; Firmawati, Aulia
Veterinary Biomedical and Clinical Journal Vol. 1 No. 1 (2019)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (672.49 KB) | DOI: 10.21776/ub.VetBioClinJ.2019.001.01.6

Abstract

Preeclampsia is one of the obstetrical problems that can cause maternal and fetal morbidity and mortality. Preeclampsia causes the fetus born prematurely and low fetal weight. This is caused by high blood pressure which causes decrease of blood delivery to the placenta, so the supply of oxygen and food to the fetus decreases. As a result, fetal development inhibits and trigger born prematurely. More fatal, this disease cause the release of placental tissue from the uterus prematurely. The aim of this study was to determine the effect of administration of triponyl sulfate as induction of increased blood pressure in preeclampsia animal models, fetal development with alizarin red staining and placental abnormalities. The experimental animals were rats Rattus norvegicus mated with male rats monomating , 4 months old and 250-300 grams body weigh. Pregnant female rats were induced by triponyl sulfate 70 mg / kg BW (k +) and without induced by triponyl sulfate (k-). The results of the study showed that there were formation of the sternal bone in k- and malformation of the sternum bone at k +. Placental abnormalities occured in k +, it could be seen in the presence of ghos villi in blood vessel abnormalities in the preeclampsia placenta caused by there was no invation of trophoblast cells in the whole or partial spiral arteries and the mean of blood pressure increased.
Solasodine and Gosipol Effectivity as a Male Contraception Inhibit LH Expression and Spermatogenesis in Rat Wulansari, Desi; Oktanella, Yudit; Hendrawan, Viski Fitri; Agustina, Galuh Chandra
Veterinary Biomedical and Clinical Journal Vol. 1 No. 2 (2019)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.671 KB) | DOI: 10.21776/ub.VetBioClinJ.2019.001.02.7

Abstract

Rabies related to increasing canine population in Bali. Uncontrolled wild animal populations caused disease transmission from animal to human. Various attempt at population control are carried out such as the use of natural contraception. Some compounds are known to have potential as antifertility are solasodine and gosipol. Solasodine is known have an antifertility affect. Gosipol, fenolic compound in Ceiba pentandra, inhibits spermatogenesis, reduce sperm concentration, motility and viability. This research aims to compare effectiveness of terong cepoka and Ceiba pentandra as antifertility. This research was conducted at Mei-November 2018. Eight-teen rats were used in this study and divided into three groups: control, P1 extract Solanum torvum 1g/kg BW and P2 extract Ceiba pentandra 0,1g/kg BW PO. Rats were treated with extract for 10 days and euthanazed at day 11. Testis were collected for histopathology using HE staining to observe spermatogenesis and using immunohistochemistry to observe LH expression. The result are analyzed using one way ANOVA P<0.05. the result show that extract solanum torvum 1g/kg BW and ceiba pentandra 0,1g/kgBW cannot reduce spermatogenesis and LH expression. This study used crude extract which still consist any other compound like antioxidant. Future study we need use isolated and pure solasodine and gosipol.
Co-Authors Abdul Hakim Abdul Samik Aditya, Siska Adrenalin, Sruti Listra Ageng Ilham Ramadhani Agung Wicaksono Agus Budiarto Agustina, Galuh Candra Agustina, Galuh Chandra Ahmad Lukman Hadiprawoto Amri, Indah Amalia Arvel Risky Widyana Aryani, Dhita Evi Assifa Mardiyah, Fraya Cahyani, Ayunda Ageng Dameanti, Fidi Nur Aini Eka Puji Desi Wulansari Desi Wulansari Dian Vidiastuti, Dian Dyah Ayu Oktavianie Edwin Widodo Elfahra Casanza Amalda Farah Alhamidah Febry Sysdityawan Ramadhan Firmawati, Aulia Fraya Assifa Mardiyah Galuh Chandra Agustina Gatot Ciptadi Hardian, Andreas Bandang Herawati . Herawati Herawati Indah Amalia Amri Intan Purwa Dewanti Kamulyan, Ujiati Kusumarini, Shelly Mariyam, Dewi Muhammad Arwani Muhammad Khuzain Ngakan Made Rai Widjaja Prasetyo, Gabriela Jeanne Giacynta Purwatiningsih, Wawid Qosimah, Dahliatul Raden Satrio Mukti Renanda Nur Al Jabbar Rizka Gitta Almaida Sruti Listra Adrenalin Tatik Hernawati Ujiati Kamulyan Viski Fitri Hendrawan Viski Fitri Hendrawan Wawid Purwatiningsih Widi Nugroho Yesica, Reza Zita Viera Pradnya R.