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All Journal Jurnal Berkala Epidemiologi Berkala Ilmu Kesehatan Kulit dan Kelamin Indonesian Journal of Tropical and Infectious Disease Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)

Rahmadewi Rahmadewi

Department Of Dermatology And Venereology, Faculty Of Medicine Universitas Airlangga / Dr. Soetomo General Academic Hospital Surabaya

Author-ID : 3286949

Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 39 Documents Claim Missing Document

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SEZARY SYNDROME MIMICKING GENERALIZED PSORIASIS VULGARIS Lynoora, Eko Rianova; Rahmadewi, Rahmadewi
Indonesian Journal of Tropical and Infectious Disease Vol. 6 No. 3 (2016)
Publisher : Institute of Topical Disease Universitas Airlangga

Sezary syndrome is the leukemic variant of cutaneous T cell lymphoma. This disease is characterized by some reddish patches or plaques all over the skin which extends to the whole body into erythroderma, lymphadenopathy. It is also indicated by the presence of atypical lymphocytes called Sezary cells. This case report is aimed to know clinical manifestation, examination and management of Sezary syndrome which clinically resembles generalized psoriasis. A 60 years old man came with scaly reddish brown plaques almost all over his body. It was accompanied by lymphadenopathy on the supraclavicular lymph node right and left as well as intense itchy. Other clinical features were alopecia, palmoplantar hyperkeratosis, onychodysthropy, facies leonine without anesthesia on the lesion and enlargement of peripheral nerve. From a laboratory test, an increase in the number of leukocytes and, Sezary cells were found in peripheral blood smear examination; while the histopathology showed focal athrophy and acanthosis of the epidermis and dense infiltration of lymphocytes in the dermo-epidermal junction and superficial dermis. Patient received 3 x 5 mg (1 cycle) of methotrexate (MTX) with 0,1% cream mometasone furoate and 3x1 tablet of CTM for adjunctive therapy. Methotrexate was discontinued because there was a disturbance in liver function and deterioration of patient's condition. After 25 days of treatment, the patient got sepsis and then passed away. Early onset of Sezary syndrome in this case is difficult to know because the clinical manifestation is similar with psoriasis vulgaris. Supporting examination such as laboratory test, blood smears and histopathology examination could help the diagnosis. The presence of lymphadenopathy, and atypical lymphocytes in the peripheral blood and the extensive skin involvement reflect the poor prognosis. The most common cause of death was sepsis.

Cutaneous Adverse Drug Reactions in Hospitalized HIV/AIDS Patients Wibisono, Yusuf; Agusni, Indropo; Hidayati, Afif Nurul; Rahmadewi, Rahmadewi; Astindari, Astindari; Septiana, Septiana; Sari, Maylita; Murtiastutik, Dwi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 2 (2021): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.2.2021.96-102

Background: Cutaneous adverse drug reaction (CADR) is the most common manifestation of drug hypersensitivity in humanimmunodeficiency virus (HIV), which presented as maculopapular rash. The incidence of CADR is found to be more commonin untreated HIV patients, and the frequency is higher in severe immunodeficiency status. Early diagnosis and appropriatetreatment give better outcomes. Purpose: To evaluate the incidence and management of CADR in HIV and acquired immunedeficiency syndrome (AIDS) patients. Methods: A retrospective descriptive study of HIV/AIDS patients with CADR whowere hospitalized at Intermediate Care and Infectious Disease Centre Dr. Soetomo General Academic Hospital. Result: Therewere more CADR cases in 2017, accounted 2.35% of the total Intermediate Care and Infectious Disease Centre RSUD Dr.Soetomo General Academic Teaching Hospital ward patients. There were more male patients (62.5%), with the mostcommonly found at the age of 25-44 years (64.3%), and which mostly (89.3%) originated from Surabaya. The most commondiagnosis was morbiliform eruption (60.7%), main complaint was red spots all over the body (45%), all of which are obscureerythematous macules. The most common causes were Duviral + Neviral antiretroviral (46%) and the most common treatmentwas dexamethasone injection. Conclusion: The incidence of CADR increased in 2017. The most frequent manifestation wasmorbilliform eruption due to Duviral+Neviral as the first line ARV treatment. Skin management varies widely in form oftopical, oral, and intravenous injection drugs, mostly using steroid class, dexamethasone intravenous injection in particular.

Efficacy of 5% Tea Tree Oil Hydrogel on Healing Morbus Hansen's Chronic Plantar Ulcer Rubianti, Marissa Astari; Ervianti, Evy; Listiawan, Muhammad Yulianto; Indramaya, Diah Mira; Rahmadewi, Rahmadewi; Hendradi, Esti; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 1 (2021): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.1.2021.28-33

Background: The damage of the peripheral nerves that occurs in Morbus Hansen (MH) patients can cause disability due to loss of sensory, motor and autonomic functions can cause wounds, infections, ulcers and disability. Ulcers are the most common cause of disability complications in MH patients and requires a certain time of healing. As many as 10-20% of MH patients experience ulcers on the soles. Tea Tree Oil (TTO) is extracted from steam distillation of the leaves and twigs of the Australian native shrub Melaleuca Alternifolia. In ulcers, TTO can work as an antimicrobial, anti-inflammatory, and antioxidant. TTO preparation in the form of hydrogel is believed to help the wound healing process. Purpose: To investigate the effect of TTO hydrogel 5% on the healing of Chronic Plantar Ulcer of Leprosy (CPUL). Methods: Tea tree oil hydrogel 5% was applied every 3 days for up to 8 weeks in 22 subjects with chronic MH plantar ulcers. Ulcer size, side effects, and possible side effects are evaluated weekly. Result: There were significant clinical and statistical differences in ulcer size (p = 0.000) and in ulcer depth (p = 0.000) after TTO hydrogel 5%. No side effects occurred in this study. The ulcer healed was 59%, the ulcer improved by 36.4%, the persistent ulcer was 4.6%, and there was no ulcer that got worse. Conclusion: TTO hydrogel 5% is effective in the healing process of chronic MH plantar pedis ulcers.

In Vitro Comparison of Antifungal Activity between Epigallocatechin Gallate EGCG) and Nystatin on Candida Sp. Stored Isolates in HIV/AIDS Patients with Oral Candidiasis Wibisono, Yusuf; Hidayati, Afif Nurul; Sawitri, Sawitri; Prakoeswa, Cita Rosita Sigit; Zulkarnain, Iskandar; Ervianti, Evy; Rahmadewi, Rahmadewi; Hendradi, Esti; Endraswari, Pepy Dwi; Murtiastutik, Dwi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 2 (2021): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.2.2021.103-109

Background: Oral candidiasis is an oral infection caused by Candida albicans. It is one of the most common opportunistic infections found in patients with Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS). Due to growing resistance and side effects to common antifungal drugs in recent years, there have been many studies on naturalsubstances as antifungal agents. In this study, Epigallocatechin gallate (EGCG) were examined for in vitro antifungal activity against Candida strains. Purpose: To compare the in vitro antifungal activity of EGCG and nystatin towards Candida sp. isolate in HIV/AIDS patients with oral candidiasis. Methods: This research was an experimental laboratory study conducted at the Dr. Soetomo General Academic Hospital, Surabaya. Forty isolates of Candida albicans and Candida non-albicans were included. The isolates were tested for antifungal activity using the well diffusion and microdilution method for nystatin 1000 IU and EGCG 1.25%. Result: Diffusion test results showed a greater inhibition zone for nystatin against all analyzed Candida strains with an average diameter for Candida albicans formed by EGCG of 2.15 mm and 7.4 mm for Candida non-albicans. Meanwhile, based on the microdilution test, EGCG was better than nystatin towards all analyzed Candida strains. This study showed EGCG Minimum Fungicidal Concentration (MFC) as high as 50% (p < 0.05). Conclusion: Nystatin antifungal activity was better than EGCG supported by a greater inhibition zone in the well diffusion method. However, the antifungal activity of EGCG was better than nystatin based on microdilution methods.

Efficacy and Side Effects of Fractional Carbon Dioxide Laser for Acne Scars, Keloids, and Striae Albae in the Dermatovenereology Clinic of Tertiary Hospital: A Retrospective Study Pramitha, Riezky Januar; Zulkarnain, Iskandar; Ervianti, Evy; Rahmadewi, Rahmadewi; Hidayati, Afif Nurul; Budiono, Budiono; Indramaya, Diah Mira; Setyaningrum, Trisniartami; Citrashanty, Irmadita; Sari, Maylita; Umborowati, Menul Ayu; Kusumaputra, Bagus Haryo; Listiawan, Muhammad Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 1 (2021): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.1.2021.19-27

Background: Fractional Carbon Dioxide (CO2) LASER has better efficacy compared to conventional LASER in treating scar tissue such as acne scars, keloids, and striae albae. However, a population with darker skin has a higher risk of side effects, especially in post-inflammatory hyperpigmentation. Purpose: To evaluate the efficacy and side effects of fractional CO2 LASER in new patients with acne scars, keloids, and striae albae in the Dermatovenereology outpatient clinic. Methods: Retrospective analysis was done on 42 medical records of patients who met the inclusion criterion, which was those who have undergone fractional CO2 LASER treatments. The efficacy and side effects of the therapy were identified and analyzed using the Statistical Package for Social Sciences (SPSS) version 17 program. Result: A total of 42.9% of patients underwent fractional CO2 LASER treatments for acne scars, while 31% and 26.1% of patients received treatments for keloids and striae albae, respectively. There was a statistically significant decrease in the degree of acne scar (2.72 ± 0.83), keloid height (2.2 ± 0.405), and striae width (0.39 ± 0.02). The statistically significant side effects were hyperpigmentation (59.5%), crustae (26.2%), erythema â‰¥ for 4 days (19%), and new acne (19%). Conclusion: Fractional CO2 LASER was effective for treating scar tissue (acne scars, keloids, and striae albae) with a higher incidence of side effects in population with darker skin and post-inflammatory hyperpigmentation.

Contact Dermatitis Knowledge Level in Batik Workers of Desa Batik, Tanjung Bumi, Bangkalan, Madura Prakoeswa, Cita Rosita Sigit; Rahmadewi, Rahmadewi; Setyaningrum, Trisniartami; Damayanti, Damayanti; Anggraeni, Sylvia; Mappamasing, Hasnikmah; Umborowati, Menul Ayu
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 2 (2021): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.2.2021.93-95

Background: Batik has been declared as a humanitarian heritage for oral and non-cultural culture. The increasing demand for batik may have a negative impact as the industry utilizes chemical agents. Hazardous chemical exposure to the skin in the batik industry may result in a high risk of occupational contact dermatitis. This study was conducted to find out the social determinants of health. Purpose: This study aims to assess the level of knowledge of the batik workers before and after health education about occupational contact dermatitis. Methods: This was an observational interview study, and the data were collected using questionnaires. This study involved 30 batik workers. We assessed the level of knowledge before and after the health education about occupational contact dermatitis. Result: There were 4 (13.3%) male participants and 26 (86.7%) female participants. The mean score of the pre-test was 66.98±10.10, and the post-test was 77.77±13.53 (p<0.05). Conclusion: The result showed a significant difference between batik workers' knowledge before and after health education about contact dermatitis.

Profile of Disability in Leprosy Patients: A Retrospective Study Geani, Silvani; Rahmadewi, Rahmadewi; Astindari, Astindari; Sawitri, Sawitri; Ervianti, Evy; Utomo, Budi; Cita Rosita Sigit Prakoeswa; Listiawan, Muhammad Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 2 (2022): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.2.2022.109-113

Background: Leprosy is a chronic granulomatous infectious disease caused by Mycobacterium leprae that affects peripheral nerves and skin. The interaction between M. leprae and Schwann cells causes irreversible damage to peripheral nervous tissue afterward disability occurs. Involvement of the major nervous trunks of the extremities can produce sensory-motor deficits. The risk factors are delay in diagnosis, gender, age, type of leprosy, duration of disease, number of affected nerves, leprosy reaction, type of treatment, socioeconomic factors, education, ethnicity, and occupation. Purpose: The aim was to study the profile of leprosy patients with disability who seek treatment in Leprosy Division Dermatovenerology Outpatient Clinic RSUD Dr. Soetomo Surabaya. Methods: This was a descriptive retrospective study of leprosy patients with disability from January 2017 to December 2019. Result: The results of this study obtained a total of 275 leprosy patients with disabilities, which consisted of 76 patients (27.6%) with grade-1 disability and 199 patients (72.4%) with grade-2 disability. The majority were male (73.4%) and aged 25-44 years old (42.2%). Other dominant risk factors were MB type leprosy (92%), duration of disease more than 12 months (52.3%), no leprosy reaction (68%), and had received multidrug therapy (45.5%). Conclusion: Knowledge of disability risk factors can assist in improving management and education to prevent disability in leprosy patients.

Dermatology Life Quality Index (DLQI) Score in Acne Vulgaris after Epigallocatechin-3-Gallate (EGCG) 3% as an Adjuvant of Tretinoin 0,025% Cream Fajrin, Farah Meriana; Citrashanty, Irmadita; Listiawan, Muhammad Yulianto; Rahmadewi, Rahmadewi; Utomo, Budi; Murtiastutik, Dwi; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.177-181

Background: Acne vulgaris (AV) often occurs at the age of puberty, most people with AV feel ashamed of their appearance. It has been believed that green tea contains high level antioxidant, such as Epigallocatechin-3-gallate (EGCG). Purpose: This study is to compare quality of life from the patient of acne vulgaris before and after using 3% Epigallocatechin-3-Gallate (EGCG) cream as adjuvant therapy of 0,025% tretinoin cream with 0,025% tretinoin cream alone in the treatment of AV. Methods: This study is a quasi-experimental study with a pre-test and post-test design, and a control group design aiming to know the difference in quality of life of 46 samples after administration of EGCG cream combined with tretinoin cream compared to the group that was given tretinoin cream alone in patients with AV for 12 weeks, and then evaluate patients satisfaction and change in quality of life after treatment using the Dermatology Life Quality Index (DLQI). Result: Statistical analysis found that there was a significant difference (p-value <0.05) in the quality-of-life value of research subjects in the treatment group when compared between the initial arrival to week 12 with a p-value of 0.000. Distribution of DLQI values in research subjects who were given 3% EGCG cream therapy as adjuvant therapy with 0.025% tretinoin cream. Conclusion: Both groups showed an improvement in the DLQI value with the interpretation of the DLQI value at week 12 being both 100%, but the treatment groups DLQI decline faster than the control groups.

Tingkat Fertilitas di Provinsi Nusa Tenggara Timur dan Yogyakarta Rahmadewi, Rahmadewi; Asih, Leli
Kesmas Vol. 6, No. 3
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Provinsi Nusa Tenggara Timur (NTT) memiliki Total Fertility Rate (TFR) tertinggi (4,2 anak) dan yang terendah adalah Provinsi Yogyakarta (1,8 anak). Tujuan penelitian ini adalah mengidentifikasi faktor-faktor yang berhubungan dengan angka fertilitas total di kedua provinsi tersebut. Penelitian ini menggunakan metode kuantitatif berdasarkan sumber data sekunder berbagai survei meliputi Survei Demografi Kesehatan Indonesia (1991-2007); Survei Kesehatan Nasional dan Survei Kesehatan Rumah Tangga tahun 2003; dan Mini Survei tahun 2007 dan 2008. Metode kualitatif dilakukan dengan diskusi kelompok terarah pada wanita pasangan usia subur (PUS) dan wawancara mendalam dengan pengelola program di kabupaten/ kota hingga ke desa/kelurahan. Ditemukan TFR di Yogyakarta sangat rendah dan sebaliknya di NTT sangat tinggi. Perbedaan TFR tersebut disebabkan oleh latar belakang demografi dan nondemografi seperti respons terhadap berbagai program penurunan fertilitas. Faktor budaya terhadap nilai anak berpengaruh besar terhadap jumlah anak yang ingin dimiliki. Tingkat pendidikan yang rendah berhubungan dengan faktor yang berpengaruh langsung terhadap pemakaian kontrasepsi, termasuk jenis kontrasepsi. Pelayanan Keluarga Berencana (KB) yang rendah memicu tingginya kebutuhan kontrasepsi yang tidak terpenuhi. Kesertaan ber-KB di NTT dan di Yogyakarta adalah 42,2% dan 66,9%. Wanita PUS yang keinginan ber-KB tidak terpenuhi masih tinggi di NTT (17,4%) dibandingkan dengan Yogyakarta (6,8%). Province of Nusa Tenggara Timur (NTT) have a total fertility rate (TFR) to the highest (4,2 children) and the lowest is the Province of Yogyakarta (1,8 children). This research is to identify factors that associated with total fertility rate in both provinces. This study uses qualitative method from the Indonesia Demography and Health Surveys (from 1991 to 2007), National Health Survey and Household Health Survey (2003), and Family Planning Mini Surveys (2007 and 2008). The qualitative method were collected using focus group discussions with fertile couple and in-depth interviews with family planning fieldworkers in district to village . The research reveals that TFR of Yogyakarta is very low and NTT is very high. The differentiation of the TFR is due to the demographic and nondemographic background as well as the respond againts the program to decrease the fertility. Cultural factor is the important one againts the value of children that will be influenced to the number of children desired in one family. Low education will be directly related to the use of contraceptive including mix contraceptive. Low family planning services which triggers the high unmet need oc contraceprive. Family Planning participation in NTT is 42,2% and 66,9% in Yogyakarta. Women on childbearing age who wishes to use contraceptive but unmet need in NTT were still high (17,4%) compared with Yogyakarta (6,8%).

Co-Authors Afif Hidayati Afif Nurul Hidayati Afif Nurul Hidayati, Afif Nurul Agatha Anindhita Ayu Ardhaninggar Agustina Tri Pujiastuti Alfrid Asditya Amanda Gracia Manuputty Amanda Gracia Manuputty Anggraeni, Sylvia Astindari Astindari Astindari Astindari, Astindari Bagus Haryo Kusumaputra, Bagus Haryo Bernadya Yogatri Anjuwita Budi Utomo Budiono Budiono Budiono Budiono Christina Avanti Cita Rosita Prakoeswa Cita Rosita Sigit Prakoeswa Cut Shelma Maharani Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Dewi Kusumawati Dhita Karina, Dhita Diah Mira Indramaya Dwi Murtiastutik DYAH FAUZIAH, DYAH Endang Wahyu Fitriani Erwin Astha Triyono Esti Hendradi Eva Lydiawati Eva Lydiawati Evy Ervianti Fajrin, Farah Meriana Farah Meriana Fajrin Geani, Silvani Hari Sukanto Indah Purnamasari INDROPO AGUSNI Irma Tarida Listiyawati Irmadita Citrashanty, Irmadita Irwadi, Irfiansyah Iskandar Zulkarnain Leli Asih Linda Astari, Linda Lynoora, Eko Rianova M. Yulianto Listiawan Mappamasing, Hasnikmah Marina Rimadhani Marina Rimadhani, Marina Maya Wardiana Maya Wardiana Maya Wardiana Maylita Sari Maylita Sari, Maylita Menul Ayu Umborowati Menul Ayu Umborowati Menul Ayu Umborowati, Menul Ayu Nurina Dhani Rahmayanti Pedia Primadiarti, Pedia Pepy Dwi Endraswari, Pepy Dwi Pramitha, Riezky Januar Putri Hendria Wardhani Rebekah Setiabudi, Rebekah Retha Retha Ridha Ramadina Widiatma Riyana Noor Oktaviyanti Riyana Noor Oktaviyanti Rubianti, Marissa Astari Ryski Meilia Novarina Sarah Fauzia Saut Sahat Pohan Sawitri Sawitri Sawitri Sawitri Sawitri Sawitri SEPTIANA SEPTIANA Septiana Widyantari Sunarso Suyoso Sunarso Suyoso, Sunarso Tasya Wikassa Tengku Riza Zarzani N Trisniartami Setyaningrum Veithzal Rivai Zainal Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono Yusuf Wibisono

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