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All Journal Jurnal Biosains Pascasarjana Jurnal Penelitian Kesehatan Suara Forikes Jurnal Kesehatan Prima Medicra (Journal of Medical Laboratory Science/Technology) Anakes: Jurnal Ilmiah Analis Kesehatan JURNAL BIOSHELL Jurnal Pengabdian Masyarakat (ABDIRA) Jurnal EduHealth Jurnal Kesehatan Kolaborasi Jurnal Pengabdian Masyarakat Prisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Jurnal Pengabdian Masyarakat Waradin Jurnal Kesehatan Amanah Jurnal Pengabdian kepada Masyarakat Innovative: Journal Of Social Science Research Jurnal Pengabdian Kepada Masyarakat: Kesehatan (JPKMK) Faedah: Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia Jurnal Pengabdian Masyarakat Kesehatan Terkini
Anas Fadli Wijaya
Universitas Dr. Soebandi
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Jurnal Biosains Pascasarjana

 1 
Regulasi Reseptor Cytotoxic T Lymphocyte Associated Protein 4 Limfosit T Terhadap Kanker dan Autoimun: Literature Review Rian Anggia Destiawan; Anas Fadli Wijaya; M Elyas Arif; Septyana Eka Rahmawati
Jurnal Biosains Pascasarjana Vol. 23 No. 2 (2021): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v23i2.2021.49-54

Abstract

Cytotoxic T Lymphocyte Associated Protein 4 (CTLA-4) adalah reseptor limfosit T yang berikatan dengan B7-1 dan B7-2 dari sel dendritik. CTLA-4 berperan menghambat kerja limfosit T. CTLA-4 diekspresikan oleh limfosit T pada fase istirahat atau setelah teraktivasi. CTLA-4 ditemukan pada sel dendritik, monosit, limfosit B, limfosit T, granulosit, dan stem sel CD34+. CTLA-4 berperan penting dalam perkembangan tumor, kanker serta autoimun. Literatur review ini bertujuan untuk membahas regulasi CTLA-4 limfosit T terhadap penyakit kanker dan autoimun. Metode: pencarian sistematis pada tiga database yaitu NCBI, science direct, dan nature dengan kata kunci “CLTA-4 and T cell and cancer and autoimmune” tahun 2021. Hasil: didapatkan 6 pilihan intervensi untuk mengurangi ekspresi CTLA-4 dan 1 intervensi untuk meningkatkan ekspresi CTLA-4. Kesimpulan: berdasarkan analisis terhadap 7 artikel penelitian, penurunan ekspresi CTLA-4 dapat menghambat pertumbuhan kanker dan peningkatan ekspresi CTLA-4 dapat menghambat berkembangnya autoimun maka dapat. 
EFFECT OF BLACK GRAPE EXTRACT ON CD4+ and CD8+ EXPRESSION IN MICE INFECTED WITH Salmonella typhimurium rian anggia destiawan; septyana eka rahmawati; anas fadli wijaya; Ahdiah Imroatul Muflihah; Mutia Hariani Nurjanah; Sholihatil hidayati; Ni Ketut Yuliana sari
Jurnal Biosains Pascasarjana Vol. 24 No. 1SP (2022): JURNAL BIOSAINS PASCASARJANA: SPECIAL ISSUE
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v24i1SP.2022.54-63

Abstract

Salmonelosis is a disease caused by the Salmonella sp. that causes a decrease in CD4+ expression. Black grape can boost the immune system through CD4+/CD8+ proliferation. The purpose of this study was to evaluate the activity of black grape extract to CD4+ and CD8+ expression in mice infected with Salmonella typhimurium. Research method is extract of black grapes, Salmonella typhimurium 108 infection, bacterial evaluation, extract therapy, flowcytometery examination, and 95% Anova test. The results of Anova test showed that the expression of CD4+ and CD8+ is not different. Biologically, an increase in CD4+ and CD8+ expression at doses of 100 mg/KgBB. A decrease in CD4+ and CD8+ expression at doses of 200 mg/KgBB and 400 mg/KgBB. Conclusion, biologically, black grape extract can increase the expression of CD4+ and CD8+ at low doses, as well as may decrease the expression of CD4+ and CD8+ at moderate to high doses.
Co-Authors Aggustin, Ayu Tri Agustin, Ayu Tri Ahdiah Imroatul Muflihah AHDIAH IMROATUL MUFLIHAH Alisa Alfiya Makki Arif Santoso Ayu Tri Agustin Azizah, Laila Camelia Nur Destiawan, Rian Anggia Elnaja, Dinar Anisa Fuzianingsih, Eka Novia Hanifiyah, Fitroh Hayati, Farhatul Hidayati, Sholihatil Holifah, Siti Nur Humairoh, Riska Tsamarah Ikhsan, Ahmad Mufti Kamaliyah, Indy Kumalasari, Nurul Chamidah Laila Camelia Laila Camelia Nur Azizah Lenny Yulia Widia Sari Leny Yulia Widia M Elyas Arif M Syaifuddin Makki, Alisa Alfiya Maruni Wiwin Diarti Meri, Meri Mufidah, Hartalina Muflihah, Ahdiah Imroatul Mutia Hariani Nurjanah Mutiurrohman, Achmad Ni Ketut Yuliana Sari Nosa Ika Cahyariza Nosa Ika Cahyariza Nurjanah, Mutia Hariani Pratikah Verdianti Purwanti, Ananda Kamila Nurcahya Putri, Diva Amalia Queen Nurul Sufi Rahma Diyan Martha Rahmawati, Ayu Sintya Citra Rahmawati, Septyana Eka Rian Anggia Destiawan Rian Anggia Destiawan Rian Anggia Destiawan RIAN ANGGIA DESTIAWAN Rian Anggia Destiawan Rossa, Handita Emilia Safitri, Yunita Diyah Sholihatil Hidayati Sigit Purwanto Siswidiani, Maya Diva Siti Maimunah Sofia Soleha, Nurmaidatus sufi, Queen Nurul Sulastri Sulastri Tilarso, Dara Pranidya Urip Urip Wafa, Muhammad Ali Widayanti, Sindi Dwi Widia, Leny Yulia Yunan Jiwintarum