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PENGARUH PEMBERIAN MINUMAN ISOTONIK TERHADAP HASIL PEMERIKSAAN KADAR BUN & KREATININ PADA MENCIT (MUS MUSCULUS) Karimah, Akhlaqul; Nidianti, Ersalina
Jurnal Analis Laboratorium Medik Vol 8 No 2 (2023): JURNAL ANALIS LABORATORIUM MEDIK
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jalm.v8i2.4605

Abstract

Metabolism in the body is influenced by electrolytes. If the electrolyte concentration is abnormal, health problems will occur. Drinks that contain electrolytes are known as isotonic drinks. The kidneys are organs that play a role in body balance, such as controlling body fluids and maintaining the balance between acidic and alkaline compounds. It is important to check BUN and creatinine to determine kidney function. The aim of the research was to analyze the effect of giving isotonic drinks on the results of BUN and creatinine examinations in mice. This type of research is experimental which uses serum from test animals in the form of mice (Mus musculus). The test animals were divided into 5 groups and each group was treated for 14 days. Then after 14 days the test animals were sampled to check BUN and creatinine levels to determine the effect of giving isotonic drinks. All data is processed statistically using SPSS. The results of the ANOVA test obtained a Sig value. 0.878 on BUN levels and Sig values. 0.265 in creatinine levels. Conclusion: With the H0 criteria rejected if the significant value is 0.05 then H0 is accepted which can state that giving isotonic drinks with volumes of 0.5 ml, 0.8 ml and 1 ml has no effect on the results of checking BUN and creatinine levels.
The Effect Of Using Personal Protection Equipment (PPE), Mileage, And Smoking Habits On Hair Lead (Pb) Levels: Pengaruh Penggunaan Alat Pelindung Diri (APD), Jarak Tempuh Dan Kebiasaan Merokok Terhadap Kadar Timbal (Pb) Rambut Wulandari, Devyana Dyah; Rohmah, Wardah; Nidianti, Ersalina; Santoso, Andreas Putro Ragil; Andini, Ary
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.1435

Abstract

Street sweepers, traffic officers, roadside sellers and motorcyclists, including students are subjects who are vulnerable to exposure to vehicle fumes. One of the air pollution generated from motor vehicle fumes is lead (Pb) which is toxic to humans and is accumulative. This study aimed to analyze the relationship between characteristic factors and lead levels in hair using the Atomic Absorption Spectroscopy (AAS) method. Respondents in this study were 32 male university students. The results showed a significance value of 0.274 (p> 0.05) on the parameter of PPE use, 0.049 (p <0.05) on the mileage parameter, and 0.576 (p> 0.05) on the smoking habit parameter. So it can be concluded that there is no effect of the use of PPE and smoking habits on hair lead levels and there is an effect of mileage on hair lead levels in student respondents.
Analysis of Balanced Diet Index Score with Fasting Blood Glucose in Adult in SDN X Sidoarjo: Analisis Skor Indeks Gizi Seimbang dengan Nilai Glukosa Darah Puasa pada Usia Dewasa di SDN X Sidoarjo Nuriannisa, Farah; Yuliani, Kartika; Nidianti, Ersalina; Rizkiyah, Mubarokator; Santoso, Rizma Defva
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 2 (2021): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i2.1611

Abstract

Adherence to Pedoman Gizi Seimbang is one of important part of non-communicable diseases prevention. Diet quality and quantity need to be assessed, thus it can detect the risk of non-communicable diseases. Healthy Eating Index (HEI) has been used in many previous studies as an indicator to examine the relationship between diet quality and disease biomarker, like fasting blood glucose (FBG). In Indonesia, the HEI has been modified to Indeks Gizi Seimbang (IGS). However there is no study that examine the relationship between IGS score and biomarker such as FBG yet. This study objective was to analyze the correlation between IGS score and FBG in adult in SDN X Sidoarjo. A cross sectional study design with 30 respondents. IGS4-105 score was measured by 2-days repeated 24h-recall, while FBG by using Glucostick method. Mann Whitney and Spearman test were performed to analyze the study results. The respondents' vegetable intake was relatively low (55.4 grams/day), while the intake of total fat (32.6%-e), saturated fat (16.7%-e), and added sugar (6.8%-e) were excessive. The intake of vegetables and non-dairy animal foods was significantly different between normal FBG group and high FBG group (respectively p value: 0.046, 0.011). The mean score of IGS4-105 was 52.3. There was no significant relationship between the IGS4-105 score and the FBG, but a positive relationship was found between the IGS score for animal foods and the FBG (r = 0.38; p = 0.04). A higher FBG was found in the group with a higher animal food IGS score.
COMMUNITY EMPOWERMENT IN THE USE OF HERBAL PLANTS TO IMPROVE THE IMMUNE SYSTEM IN SIMO ANGIN-ANGIN VILLAGE, WONOAYU DISTRICT, SIDOARJO REGENCY Maat, Suprapto; Nidianti, Ersalina; Kurniasari, Diyan Wahyu; Algristian, Hafid
Community Service Journal of Indonesia Vol 5 No 2 (2023): Community Service Journal of Indonesia
Publisher : Institute for Research and Community Service, Health Polytechnic of Kerta Cendekia, Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36720/csji.v5i2.604

Abstract

Medical plants that have uses or properties in health treatment. Currently, the use of Indonesian herbal plants is only limited to being used as cooking spices and has not been optimally used as medicine to increase the body's endurance. The aim of this community service activity is as an effort to prevent disease by increasing the body's immunity after the Covid-19 pandemic. The method applied in this community service activity is community empowerment in the use of herbal plants to improve the immune system in Simo Angin - Angin village, Wonoayu District through the stages of lectures, demonstrations and collaboration. The target participants were PKK women from Simo Angin-angin Village, Wonoayu District, Sidoarjo Regency, a total of 30 people. The results obtained were counseling and education on the benefits of Indonesian herbal plants using posters and brochures. The results of the community empowerment activities in Simo Angin-angin village are through making herbal plants as drinks in the form of herbal medicine to increase the body's immunity. Participants can understand the potential of herbal plants to be processed into drinks that can be consumed to maintain health after Covid-19. The conclusion is that the PKK women in Simo Angin-angin Village, Wonoayu District, Sidoarjo Regency know how to prevent disease by using Indonesian herbal plants and producing herbal drink concoctions to increase the body's immunity. The next recommendation for community service activities is processing residents' empty land for herbal plants and community empowerment through the production of herbal drinks to commercialization.
Perbedaan Teknik Pemasangan Tourniquet Terhadap Kadar Magensium Serum Safitri, Hana; Wulan, Wieke Sri; Nidianti, Ersalina
JPP JURNAL KESEHATAN POLTEKKES PALEMBANG Vol 19 No 1 (2024): (JPP) Jurnal Kesehatan Poltekkes Palembang
Publisher : Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jpp.v19i1.2144

Abstract

Background: Magnesium is an electrolyte that plays an important role in the body's reactions, because if there is a lack or too much magnesium it will cause organ dysfunction and even a person's death. That is the reason why errors in magnesium measurements can create serious conditions for patients if laboratory results are inaccurate. The hemoconcentration state of the sample can influence the final results obtained. The aim of the study was to determine the difference between tourniquet application techniques and the results of serum magnesium levels. Methods: This type of research is experimental research. In the first group of treatments, a tourniquet was dabbed which was maintained only until the vein could be accessed and the second group was dabbed with a tourniquet until the blood drawn reached the desired volume at the research object, measured and collected at the same time. Then the serum magnesium test was measured. Results:Research results on differences in tourniquet application techniques in serum magnesium examination. This research involved 20 respondents with a total sample of 40 samples (respondents' blood was taken twice). The research results mean magnesium levels with the released tourniquet technique were 2.8 mg/dL, higher than the second intervention, namely the tourniquet technique which was maintained at 2.5 mg/dL. The statistical results of the paired T-test carried out obtained data with a p-value of 0.849, which means p-value > 0.05. Conclusion: There was no significant difference between magnesium levels with the tourniquet removed and the tourniquet maintained to a volume of 3 cc.
Hubungan Kejadian Sifilis dengan Human Immunodeficiency Virus (HIV)1.2 Pada Pekerja Seks Komersial Fitri Aisyah Haddad; Rahayu Anggraini; Suprapto Ma’at; Ersalina Nidianti
Cerdika: Jurnal Ilmiah Indonesia Vol. 4 No. 8 (2024): Cerdika: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/cerdika.v4i8.833

Abstract

Pekerja Seks Komersial (PSK) biasanya menularkan penyakit menular seksual, sehingga pada kesempatan ini ingin mengetahui penyakit menular seksual (Sifilis, HIV1.2) yang banyak terjadi pada PSK. Penelitian ini menggunakan metode observasional pendekatan desain cross sectional analytic, dengan tujuan untuk mengetahui hubungan kejadian sifilis dengan HIV1.2 pada pekerja seks komersial. Penelitian dilakukan pemeriksaan sifilis metode Rspid dari total responden dan HIV1.2 metode ELISA (Enzym–Linked Immunosorbent Assay). Hasil penelitian didapatkan kejadian sifilis sebanyak 6,7% positif dan 93,7% negatif. Hasil pemeriksaan HIV1.2 didapatkan 6,7% reaktif dan 93,7% non rekatif. Hasil analisis statistik terdapat hubungan yang signifikan kejadian sifilis dengan HIV1.2 dengan nilai p value 0,017 (p<0,05). Kesimpulan, kejadian sifilis dan HIV1.2 terjadi pada individu sama yang artinya teori bakterial vaginosis yang menyatakan kondisi vagina yang bermasalah lebih mudah terinfeksi penyakit menular seksual terutama yang memiliki penyimpangan oral seks
Comparison of variaton in extract concentration onion leaf (Allium fistulosum L.) to mortality larvae Aedes aegypti mosquito instar III Wulandari, Siska; Lukiyono, Yauwan Tobing; Andini, Ary; Nidianti, Ersalina
Environmental and Toxicology Management Vol. 3 No. 2 (2023): Environmental drivers of vector-borne: Impact and mitigation
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/etm.v3i2.6389

Abstract

Dengue Hemorrhagic Fever (DHF) is a disease caused by the Dengue virus which is transmitted through the Aedes aegypti mosquito. DHF is caused by the Dengue virus whose main vector is the Aedes aegypti mosquito and the secondary vector is the Aedes albopictus mosquito. Eradicating Aedes aegypti and Aedes albopictus is one way that can be done to prevent the spread of the Dengue virus. Control of the dengue vector can be carried out on larvae and adult mosquitoes with the aim of breaking the chain of transmission. One way that can be done is by using a natural larvicide which utilizes the Allium fistulosum plant which contains secondary metabolite compounds including phenolics, flavonoids and tannins which can kill larvae. This study aims to determine the comparison of variations in the concentration of Allium fistulosum leaf extract on the mortality of Aedes aegypti instar III. The type of research used in this research was experimental with a completely randomized design (RAL). The potential level of the extract is reviewed from the Lethal Concentration (LC50) and Lethal Time (LT50) values. The data obtained were analyzed using a probit regression test or probit analysis to determine the potential of Allium fistulosum extract as an alternative larvicide for third instar Aedes aegypti larvae and stated as Lethal Concentration (LC50) and Lethal Time (LT50) with a confidence level of 95.0%. The results of the research show that Allium f istulosum leaf extract has the potential as an alternative larvicide for the death of third instar Aedes aegypti larvae as proven by a p-value of 0.000 (< 0.05) with a value of LC50-6 hours is 52.850%, LC50-8 hours is 42.674%, LC50-24 hours is 30.900%, LT50-20% is 37.674 hours, LT50-30% is 24.423 hours and LT50-40% is 14.954 hours.
Effectiveness of the repellent of kawista leaf extract (Limonia acidissima) against Aedes aegypti mosquitoes Qotrinnada, Nabilah; Lukiyono, Yauwan Tobing; Prayekti, Endah; Nidianti, Ersalina
Environmental and Toxicology Management Vol. 3 No. 2 (2023): Environmental drivers of vector-borne: Impact and mitigation
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/etm.v3i2.6390

Abstract

Synthetic insecticides containing highly effective active substances such as DEET (N,N-diethyl-meta toluamide) to prevent and control Dengue Hemorrhagic Fever can have adverse effects on health and the environment. Kawista leaves (Limonia acidissima) have the potential as a natural insecticide against Aedes aegypti mosquitoes because they contain secondary metabolite compounds namely phenols, flavonoids, saponins, and terpenoids. This study aims to determine the effectiveness of the repellent power of kawista leaf extract (Limonia acidissima) against Aedes aegypti mosquitoes. This study used experimental method with post-test only control group design. The sample used was 25 adult of Aedes aegypti mosquitoes in each treatment. The ethanol extract of kawista leaves was made in the form of a spray with a concentration of 25%, 50% concentration, and 75% concentration. The 25% concentration, 50% concentration, and 75% concentration of kawista leaf extract have an effective repellent power against Aedes aegypti mosquitoes, namely 15.22%, 46.20%, and 70.08%, respectively. The results of the analysis of kawista leaf extract against Aedes aegypti mosquitoes obtained ED50 (Effective Dose 50) at a concentration of 60.343% and ED99 (Effective Dose 99) at a concentration of 124.452%. From the results of the study, it can be concluded that kawista leaves have the ability to repel Aedes aegypti mosquitoes.
Comparison of Toxoplasma gondii counts in chicken and duck brain samples sold at Keputran Market, Surabaya Cahyani, Yuliana Dwi Kurnia; Lukiyono, Yauwan Tobing; Nidianti, Ersalina; Romdloni, Muhammad Afwan
Environmental and Toxicology Management Vol. 3 No. 3 (2023): Soil Health, Animal Health, and Water Quality in Agroecological Systems
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/etm.v3i3.6394

Abstract

Toxoplasmosis is a zoonotic disease caused by the parasite Toxoplasma gondii, which is transmitted through cats as definitive hosts and also infect poultry. This occurs because poultry ingest food contaminated with oocysts of Toxoplasma gondii. The most commonly consumed poultry are chicken and duck. This study aims to compare the counts of Toxoplasma gondii in chicken and duck brain samples sold at Keputran Market, Surabaya. This research is an analytical observational study with a cross-sectional approach, using direct preparation and flotation methods as research instruments. The samples in this study consisted of 24 chicken brain samples and 24 duck brain samples. The statistical analysis used was the Chi-Square test. The results showed that 16.7% (8 samples) of the chicken brain samples were positive and 33.3% (16 samples) were negative for Toxoplasma gondii. Meanwhile, 12.5% (6 samples) of the duck brain samples were positive and 37.5% (18 samples) were negative for Toxoplasma gondii. The data were analyzed using the Chi-Square test, resulting in a value of 0.752 (≥0.05), indicating that there is no significant difference in the presence of Toxoplasma gondii between the chicken and duck brain samples sold at Keputran Market, Surabaya.
Sintesis Nanopartikel Bovine Serum Albumin Kombinasi Cisplatin dan Asam Folat Sebagai Kandidat Antikanker Nidianti, Ersalina; Andini, Ary; Rukman, Nia Kurniaty
CHEESA: Chemical Engineering Research Articles Vol. 3 No. 2 (2020)
Publisher : Universitas PGRI Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/cheesa.v3i2.7742.79-87

Abstract

Kanker adalah penyakit tidak menular yang menyebabkan morbiditas dan mortalitas di seluruh wilayah dunia. Salah satu pengobatan kanker adalah dengan menggunakan obat kemoterapi cisplatin. Namun cisplatin memiliki efek samping yang bersifat toksik jika dikonsumsi dalam dosis dan waktu tertentu. Kombinasi nanopartikel bovine serum albumin (BSA) yang mengandung cisplatin dikembangkan dengan modifikasi ikatan menggunakan asam folat sebagai solusi alternatif meminimalisir efek toksik yang dihasilkan dan mengoptimalkan sistem pengiriman obat. Tujuan penelitian adalah sintesis kombinasi nanopartikel BSA yang mengandung cisplatin dan modifikasi ikatan menggunakan asam folat sebagai kandidat antikanker. Penelitian ini dilakukan melalui sintesis dengan metode desolvasi. Hasil penelitian menunjukkan bahwa nanopartikel BSA yang dikombinasi dengan cisplatin dan asam folat telah berhasil disintesis. Analisis FT-IR menunjukkan bahwa ada gugus fungsi O-H alkohol, C-H, C-C, NO2 yang berperan dalam sintesis nanopartikel. Analisis XRD menunjukkan adanya pergeseran peak dari NP-BSA 31,69 menjadi As-CP-NP-BSA 34,45; ukuran nanopartikel NP-BSA 2,38 nm dan As-CP-NP-BSA 2,62 nm sedangkan analisis SEM-EDX diketahui ada unsur C, O, Mg, Cl dan Pt.
Co-Authors Adinda Priyanti Dewi Afianti Diah Anjelia Aidilfi Akbar, Dimas Arendra Aini, Fadlilah Nur Aisah Humairoh Alfina Andasari Algristian, Hafid Alifia Qurotaaini Andini Devi Rizkiyah Andini, Ary Andreas Putro Ragil Santoso, Andreas Putro Ragil Anggara Kidung Pranata Annisa Syahrah Arif Rahman Hakim Ary Andini Atika Maulida Inastiti Aulia, Ilmiah Alvi Nisa Ayu, Friska Bismi Aisyah Rahma Putri Budury, Syiddatul Cahyani, Yuliana Dwi Kurnia Charissa Balqis Chika Nur Azizah Dea Ayu Rahmawati Desi Susanti Devyana Dyah Wulandari Devyana Dyah Wulandari Dewi Masithah Dina Kamelia Dinda Enka Nita Endah Budi Permana Putri Evi Utul Kasanah Fadilah Nisa Purwanti Fadlilah Nur Aini Fahrizal Amin Nurfaizi Farah Dina Amalia Farah Nuriannisa Farhatu Aini Fauziyah, Luqiana Fitri Aisyah Haddad Giftania Wardani Sudjarwo Gilang Nugraha Halimah Prisilia Hartatiek Nila Herliani Rahmania Sari Herlianti Anggun Puspita Ningrum Herlianti Anggun Puspita Ningrum Herlianti Anggun Puspita Ningrum Hidayat, Muhammad Taufiq Himawan, Toto Hudzaifah Hamidy Ika Maysaroh Lesparwati Ilmiah Alvi Nisa Aulia Intan Oktariza Nuraulya Putri Irmawati Irmawati KARIMAH, AKHLAQUL Khoirul Ngibad Khusnah, Hidayatul Kombih, Muhammad Fifin Kurniasari, Diyan Wahyu Luqiana Fauziyah Maat, Suprapto Mardhotillah, Rachma Rizqina Marotur Rohima Miftakhul Dwi Ersanti Miladiya, Feby Ayu Muhammad Afwan Romdloni Muhammad Afwan Romdloni Muhammad Taufiq Hidayat Mutmainnah Nadzirah Sylvia Nandasari, Anggy Dwipa Nathalya Dwi Kartika Sari Nathalya Dwi Kartika Sari Ngiluhtara Aditiya Putri Nila Dwi Utami Nisrina Salsabila Firdaus Nur A'isyah Oktavianingrum Nurdinata, Sandra Maulida Nuris Lutfika Nurul Hidayatih Nurul Munawaroh Pertiwi, Penti Pertiwi, Sarafia Prayekti, Endah Puspitasari, Fike Putri, Bismi Aisyah Rahma Putri, Ngiluhtara Aditiya Qotrinnada, Nabilah Rahayu Anggraini Rahayu Anggraini Rahmawati Fitri Awalia Raniyah Diva Rosalbah Rezky Dwinda Pratiwi Rizka Amalia Rizka Amalia Rizkiyah, Mubarokator Rohmah, Wardah Rukman, Nia Kurniaty Safitri, Hana Salfa Salsabilah Zain Salfa Salsabilah Zain Salim, Hotimah Masdan Santoso, Rizma Defva Sarafia Pertiwi Sari, Herliani Rahmania Sari, Yuni Nur Malita Saumia Khoirunnisa Syadzila Septyanengrum, Rita Silva Havadoh Shelagita Siska Wulandari, Siska Siti Basiroh Sri Surya Suciati Suciati, Sri Surya Sunaryo, Merry Suprapto Maat Suprapto Maat Suprapto Ma’at Syadzila, Saumia Khoirunnisa Syahrah, Annisa Utami, Nila Dwi Utomo, Edi Priyo Widi Agustin Wulandari Widya Novita Sari Widya Putra, Bima Arya Wieke Sri Wulan Wieke Sri Wulan Wulan, Wieke Sri Yauwan Tobing Lukiyono Yuliani, Kartika Yuni Nur Malita Sari Zain, Salfa Salsabilah