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All Journal Jurnal Ilmu Pertanian Indonesia Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences METAMORFOSA Journal of Biological Sciences Jurnal Biologi Udayana El-Hayah : Jurnal Biologi Jurnal Sains Peternakan Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) Pharmasipha JURNAL ILMIAH PETERNAKAN TERPADU Journal of Dedicators Community Biota Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) JSMARTech : Journal of Smart Bioprospecting and Technology J-PEN Borneo : Jurnal Ilmu Pertanian Jurnal Sains Alami (Known Nature) Berkala Penelitian Hayati Jurnal Riset Perikanan dan Kelautan Jurnal Sains Alami (Known Nature) MERDEKA: Jurnal Ilmiah Multidisiplin KOPEMAS Exhibition and Seminar on Science and Creative Technology – Al Azhar Proceeding Genbinesia Journal of Biology
Nurul Jadid Mubarokati
Universitas Islam Malang
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Pendampingan Inovasi Olahan Es Krim Jahe-Kencur pada Kelompok Wanita Tani di Mangliawan Malang Nour Athiroh; Nurul Jadid Mubarakati
Journal of Dedicators Community Vol 4, No 2 (2020)
Publisher : Universitas Islam Nahdlatul Ulama Jepara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34001/jdc.v4i2.1107

Abstract

Ginger and galangal powder are less attractive to people in Mangliawan village. The cooperative's ginger powder sales business experienced a setback. The aim is to provide creativity and innovation assistance to this ginger powder as a raw material for ice cream. The phenomenon of this decade appears in various variants of ice cream, but there is no ginger-galangal based ice cream business yet. The service method consists of: 1) program socialization, 2) training in making ice cream, 3) formation of non-governmental organizations as program partners, 4) program monitoring, 5) focus group discussion, f) evaluation. Measurement of the impact of the activity was carried out using a questionnaire technique which aims to obtain a direct picture of the community in Mangliawan village. The results of the service program are 1) the public's knowledge of the potential of kencur ginger and its processing has increased; 2) Partners know how to make kencur ginger ice cream; 3) public knowledge of the benefits of ginger ice cream increases; 4) There is a desire of the respondent to open a ginger-kencur ice cream business plan and increase the economic level.
Paparan benalu (teh dan mangga) terhadap kadar Superoksida Dismutase (SOD) serum tikus hipertensi model preventif Nur Mufida; Nour Athiroh Abdoes Sjakoer; Nurul Jadid Mubarakati
Jurnal Biologi Udayana Vol 26 No 1 (2022): JURNAL BIOLOGI UDAYANA
Publisher : Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JBIOUNUD.2022.v26.i01.p06

Abstract

Salah satu penyakit yang menjadi masalah kesehatan karena terjadi peningkatan prevalensi setiap tahunnya adalah penyakit hipertensi. Tingginya ROS (Reactive Oxygen Species) dalam tubuh akan meningkatkan pembentukan radikal bebas berlebih dan membuat antioksidan endogen SOD (Superoxide dismutase) terpakai secara berlebih sehingga menjadi penyebab munculnya penyakit hipertensi. Tanaman herbal benalu teh dan benalu mangga merupakan tumbuhan yang memiliki potensi sebagai pencegahan hipertensi dengan meningkatkan aktivitas SOD dalam tubuh. Tujuan penelitian ini untuk mengetahui pengaruh pemaparan ekstrak metanol kombinasi benalu teh dan benalu mangga (EMKBTBM) terhadap peningkatan kadar SOD serum pada tikus hipertensi yang diinduksi DOCA-Garam menggunakan model preventif. Pada penelitian ini menggunakan metode eksperimental dengan hewan uji berjumlah 25 ekor tikus wistar jantan yang terbagi menjadi 5 kelompok dan terdapat 5 ekor tikus pada setiap kelompok, yaitu kontrol negatif (K-), kontrol positif (K+), dan kelompok dengan perlakuan pemaparan EMKBTBM (P1) dosis 50 mg/kgBB, (P2) dosis 100 mg/kgBB, dan (P3) dosis 200 mg/kgBB. Didapatkan hasil penelitian yang menunjukkan bahwa pemaparan EMKBTBM berpengaruh terhadap peningkatan aktivitas SOD serum pada tikus hipertensi dengan perbedaan yang signifikan pada nilai reratanya antar semua kelompok dengan nilai p <0,05. Efektivitas pengaruh pemaparan benalu teh dan benalu mangga dikendalikan oleh EMKBTBM dosis 100 mg/KgBB yang merupakan dosis efektif dalam meningkatkan kadar SOD serum tikus model hipertensi DOCA-Garam.
Pengaruh ekstrak metanolik kombinasi benalu teh dan benalu mangga terhadap histopatologi hepar tikus model hipertensi (DOCA-Garam) Arina Roikhana; Nour Athiroh Axzbdoes Sjakoer; Nurul Jadid Mubarakati
Jurnal Biologi Udayana Vol 26 No 1 (2022): JURNAL BIOLOGI UDAYANA
Publisher : Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JBIOUNUD.2022.v26.i01.p13

Abstract

Hipertensi merupakan salah satu penyakit yang menyebabkan kematian utama pada manusia serta berhubungan dengan penyakit kardiovaskular. Hipertensi dapat merusak organ hepar yang berhubungan dengan Reactive Oxygen Species (ROS). Benalu mangga dan teh bermanfaat sebagai obat herbal untuk menjaga kesehatan tubuh manusia. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak metanol kombinasi benalu teh dan mangga terhadap histopatologi hepar tikus hipertensi (DOCA-Garam), desain eksperimen yang digunakan yaitu rancangan acak lengkap sebanyak 25 ekor tikus wistar jantan yang dikelompokkan menjadi 5 perlakuan yaitu kontrol (-) = 0 mg/KgBB EMKBTBM, kontrol (+) = 15 mg/KgBB DOCA-Garam, P1, P2, P3 masing- masing 50, 100, 200 mg/KgBB EMKBTBM. Analisis data yang digunakan adalah uji ANOVA two way yaitu JAMOVI dengan versi 1.1.9.0. Hasil penelitian ini menunjukkan bahwa terdapat perbedaan yang sangat nyata (p-value) <0.05 pada zona 1, 2, dan 3 jika dibandingkan dengan semua kelompok perlakuan, dan semua kelompok perlakuan yaitu antara kelompok kontrol (+) dengan kontrol (-), perlakuan 1, 2, dan 3 berbeda nyata terhadap rerata kerusakan sel (piknosis, karioreksis, kariolisis) hepatosit hepar. Dibuktikan dengan hasil analisis yang menyatakan p-value <0.05 yaitu <0.001, sehingga pemberian ekstrak metanol kombinasi benalu teh dan mangga dapat mengurangi nekrosis (piknosis, karioreksis, dan kariolisis) pada hepatosit organ hepar tikus hipertensi.
Gambaran Histopatologi Otak Pada Tikus Hipertensi (DOCA-Garam) yang Dipapar Ekstrak Metanolik Kombinasi Benalu Teh dan Benalu Mangga Model Preventif Dyan Aprillia Susanti; Nour Athiroh Abdoes Sjakoer; Nurul Jadid Mubarokati
Jurnal SAINS ALAMI (Known Nature) Vol 5, No 1 (2022)
Publisher : FMIPA UNISMA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/j.sa.v5i1.15541

Abstract

Hypertension is an increase in blood pressure that exceeds normal limits. In patients with hypertension, systolic blood pressure is 140 mmHg and diastolic blood pressure is 90 mmHg and comes from a complex and interconnected environment. Hypertension is a non-communicable disease that can cause death in humans and is closely related to cardiovascular disease. Hypertension is considered the main cause of 9.4 million deaths that occur in the world's population every year. Disorders of blood vessels around the brain due to hypertension can cause death. The purpose of this study was to determine the effectiveness of the methanolic extract of the combination of Mango Mistletoe and Mistletoe Tea (EMKBTBM) given to rats with hypertension model on the histopathological features of the brain in hypertensive rats (DOCA-salt) preventive model. The method used in this study was the true experimental method and the RAL research design on 25 male wistar rats with 3 treatments (PI, PII, PIII), (K-) group without any treatment (without administration of DOCA Salt and EMKBTBM) and (K+) using DOCA-Salt induction without giving EMKBTBM, and 5 times replication. The EMKBTBM was given with a ratio of mango mistletoe: tea mistletoe which was 3:1 and then given at a dose of 50, 100, 200 mg/KgBB in the treatment of PI, PII, PIII. Data analysis was carried out by using ANOVA statistical test using the JAMOVI application. Based on the results of the study, it was shown that giving EMKBTBM to rats had the effect of reducing the amount of damage (necrosis) in the white matter area of the brain. The administration of EMBTBM at a dose of 50 mg/KgBW was the most optimum dose in reducing the amount of white matter cell necrosis in the male wistar rat brain.Keywords:3 Brain Necrosis, Hypertension, Mango Mistletoe, Tea MistletoeABSTRAKHipertensi merupakan bertambahnya tekanan darah melebihi batas normal. Pada penderita hipertensi, tekanan darah sistolik 140 mmHg dan tekanan darah diastolik  90 mmHg serta berasal dari lingkungan yang kompleks dan saling berhubungan. Hipertensi ialah penyakit tidak menular yang dapat mengakibatkan kematian pada manusia dan berkaitan erat dengan penyakit kardiovaskular. Hipertensi dianggap sebagai sebab utama 9,4 juta kematian yang terjadi pada penduduk dunia pada setiap tahunnya. Gangguan pembuluh darah disekitar otak akibat hipertensi dapat menebabkan kematian. Tujuan dari penelitian ini adalah untuk mengetahui efektivitas Ekstrak Metanolik Kombinasi Benalu Mangga dan Benalu Teh (EMKBTBM) yang diberikan pada tikus model hipertensi terhadap gambaran histopatologi otak pada tikus hipertensi (DOCA-garam) model preventif. Metode yang digunakan dalam penelitian ini menggunakan metode true eksperimental serta desain penelitian RAL pada 25 ekor tikus wistar jantan dengan 3 perlakuan (PI, PII, PIII), (K-) kelompok tanpa perlakuan apapun (tanpa pemberian DOCA Garam dan EMKBTBM) dan (K+) menggunakan induksi DOCA-Garam tanpa pemberian EMKBTBM, serta 5x ulangan. Pemberian EMKBTBM dengan perbandingan benalu mangga : benalu teh yaitu 3:1 kemudian diberikan dengan dosis 50, 100, 200 mg/KgBB pada perlakuan PI, PII, PIII. Analisis data dilakukan dengan uji statistic ANOVA menggunakan aplikasi JAMOVI. Berdasarkan hasil penelitian menunjukkan pemberian EMKBTBM pada tikus mempunyai efek yaitu dapat mengurangi jumlah kerusakan (nekrosis) di area white matter otak. Pemberian EMBTBM dengan dosis 50 mg/KgBB merupakan dosis paling optimum dalam menurunkan jumlah nekrosis sel white matter otak tikus wistar jantan.Kata kunci: Benalu Teh, Benalu Mangga, Hipertensi, Nekrosis Otak
Uji Toksisitas Sub-Kronik 28 Hari Ekstrak Metanolik Daun Benalu Teh Dan Benalu Mangga Terhadap Fungsi Jantung Tikus Wistar Betina M. Abdul Qodir Jailani; Nour Athiroh Abdoes Sjakoer; Nurul Jadid Mubarakati
Jurnal Ilmiah Biosaintropis (Bioscience -Tropic) Vol 8 No 1 (2022): Agustus 2022
Publisher : Fakultas Matematika & Ilmu Pengetahuan Alam - Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (934.045 KB) | DOI: 10.33474/e-jbst.v8i1.364

Abstract

Benchmark damage to heart function lies in LDH, CPK, CK-MB as well as histopathology of heart organs. This study aims to determine the 28-day subchronic toxicity of methanolic extracts of tea parasites and mango parasites (EMBTBM) on the heart function of female Wistar rats by experimental methods. In analyzing the data, one way ANOVA test is used, namely SPSS with version 1.0 1.0. A total of 20 female Wistar rats were used as test animals. Then divided into 4 treatments, namely control, treatment 1 dose 250 mg/KgBW, treatment 2 dose 500 mg/KgBW and treatment 3 dose 1000 mg/KgBW, each containing 5 mice. From the results of the study, it was found that EMBTBM positively contained flavonoids in the form of quercetin and rutin to reduce LDH, CPK, and CK-MB levels in female Wistar rats, and be safe against the histopathology of the heart organs of female Wistar rats.
Bovine And Human Zona Pellucida 3 Gene Glycans Site Prediction Using In Silico Analysis Nurul Jadid Mubarakati; Aulanni'am Aulanni'am; Sutiman Bambang Sumitro; Gatot Ciptadi
Journal of Tropical Life Science Vol. 4 No. 3 (2014)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.04.03.08

Abstract

Zona pellucida is one of the protective layer of the egg cell and has a function as an intermediary species-specific fertilization. Glycoproteins of human and bovine zona pellucida is composed of three types, namely ZP1, ZP2 and ZP3. ZP3 gene has amino acid sequence homology with other mammals. Oligosaccharides components of the zona pellucida glycans are composed from units of asparagine residues (N -linked) and serine/threonine (O -linked). The aims of this study was to analyze the DNA sequences of human and bovine and further predicts glycans site on amino acid sequence of human and bovine ZP3. In this study, ZP3 gene fragments have been isolated from bovine and humans were analyzed in Silico. This work were conducted by comparing the data of DNA sequence from human and bovine PCR product using NCBI BLAST. The results showed that there were similarities at amino acid positions number 23-38. bZP3 sequence had three glycans site (Asn-X-Thr/Ser) and one site on hZP3 glycans. One of the sites was conserved between the two species.
Gambaran Histopatologi Otak Pada Tikus Hipertensi (DOCA-Garam) yang Dipapar Ekstrak Metanolik Kombinasi Benalu Teh dan Benalu Mangga Model Preventif Dyan Aprillia Susanti; Nour Athiroh Abdoes Sjakoer; Nurul Jadid Mubarokati
Jurnal SAINS ALAMI (Known Nature) Vol. 5 No. 1 (2022)
Publisher : FMIPA UNISMA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/j.sa.v5i1.15541

Abstract

Hypertension is an increase in blood pressure that exceeds normal limits. In patients with hypertension, systolic blood pressure is 140 mmHg and diastolic blood pressure is 90 mmHg and comes from a complex and interconnected environment. Hypertension is a non-communicable disease that can cause death in humans and is closely related to cardiovascular disease. Hypertension is considered the main cause of 9.4 million deaths that occur in the world's population every year. Disorders of blood vessels around the brain due to hypertension can cause death. The purpose of this study was to determine the effectiveness of the methanolic extract of the combination of Mango Mistletoe and Mistletoe Tea (EMKBTBM) given to rats with hypertension model on the histopathological features of the brain in hypertensive rats (DOCA-salt) preventive model. The method used in this study was the true experimental method and the RAL research design on 25 male wistar rats with 3 treatments (PI, PII, PIII), (K-) group without any treatment (without administration of DOCA Salt and EMKBTBM) and (K+) using DOCA-Salt induction without giving EMKBTBM, and 5 times replication. The EMKBTBM was given with a ratio of mango mistletoe: tea mistletoe which was 3:1 and then given at a dose of 50, 100, 200 mg/KgBB in the treatment of PI, PII, PIII. Data analysis was carried out by using ANOVA statistical test using the JAMOVI application. Based on the results of the study, it was shown that giving EMKBTBM to rats had the effect of reducing the amount of damage (necrosis) in the white matter area of the brain. The administration of EMBTBM at a dose of 50 mg/KgBW was the most optimum dose in reducing the amount of white matter cell necrosis in the male wistar rat brain.Keywords:3 Brain Necrosis, Hypertension, Mango Mistletoe, Tea MistletoeABSTRAKHipertensi merupakan bertambahnya tekanan darah melebihi batas normal. Pada penderita hipertensi, tekanan darah sistolik 140 mmHg dan tekanan darah diastolik  90 mmHg serta berasal dari lingkungan yang kompleks dan saling berhubungan. Hipertensi ialah penyakit tidak menular yang dapat mengakibatkan kematian pada manusia dan berkaitan erat dengan penyakit kardiovaskular. Hipertensi dianggap sebagai sebab utama 9,4 juta kematian yang terjadi pada penduduk dunia pada setiap tahunnya. Gangguan pembuluh darah disekitar otak akibat hipertensi dapat menebabkan kematian. Tujuan dari penelitian ini adalah untuk mengetahui efektivitas Ekstrak Metanolik Kombinasi Benalu Mangga dan Benalu Teh (EMKBTBM) yang diberikan pada tikus model hipertensi terhadap gambaran histopatologi otak pada tikus hipertensi (DOCA-garam) model preventif. Metode yang digunakan dalam penelitian ini menggunakan metode true eksperimental serta desain penelitian RAL pada 25 ekor tikus wistar jantan dengan 3 perlakuan (PI, PII, PIII), (K-) kelompok tanpa perlakuan apapun (tanpa pemberian DOCA Garam dan EMKBTBM) dan (K+) menggunakan induksi DOCA-Garam tanpa pemberian EMKBTBM, serta 5x ulangan. Pemberian EMKBTBM dengan perbandingan benalu mangga : benalu teh yaitu 3:1 kemudian diberikan dengan dosis 50, 100, 200 mg/KgBB pada perlakuan PI, PII, PIII. Analisis data dilakukan dengan uji statistic ANOVA menggunakan aplikasi JAMOVI. Berdasarkan hasil penelitian menunjukkan pemberian EMKBTBM pada tikus mempunyai efek yaitu dapat mengurangi jumlah kerusakan (nekrosis) di area white matter otak. Pemberian EMBTBM dengan dosis 50 mg/KgBB merupakan dosis paling optimum dalam menurunkan jumlah nekrosis sel white matter otak tikus wistar jantan.Kata kunci: Benalu Teh, Benalu Mangga, Hipertensi, Nekrosis Otak
Pengaruh Ekstrak Benalu Mangga Terhadap Kadar Malondealdehid (MDA) pada Tikus Hipertensi yang Dipapar DOCA- Garam Rahayu Dwi Lestari; Nour Athiroh Abdoes Sjakoer; Nurul Jadid Mubarakati
Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) Vol 8 No 2 (2023): Januari 2023
Publisher : Fakultas Matematika & Ilmu Pengetahuan Alam - Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/e-jbst.v8i2.402

Abstract

Hypertension is a chronic disease that is most often found in society. Hypertension is associated with increased production of superoxide radicals and endothelial dysfunction, which causes oxidative stress characterized by increased levels of MDA. Mango mistletoe contains secondary metabolic compounds such as flavonoids which act as natural antioxidants. The use of antioxidants from manga parasites is an alternative to neutralize the increase in MDA in the body and neutralize free radicals. This study aims to determine the levels of MDA in hypertensive rats (DOCA-Salt) exposed to Mango mistletoe Methanolic Extract (EMBM) for 14 days. This study used the true experimental design method with completely randomized design on 50 male Wistar rats, differentiated into 5 treatments, namely control (-), control (+), treatment 1 dose 50 mg / KgBB, treatment 2 doses of 100 mg / KgBB and treatment 3 doses 200 mg / KgBW. Each treatment had 5 replications. Data analysis used oneway ANOVA and post hoc tests, namely JAMOVI version 1.1.9.0 which was used to determine differences in pulmonary MDA levels between groups and pulmonarymalondialdehyde (MDA) were analyzed by spectrophotometry. The results of this study indicated that pulmonary MDA levels in hypertensive rats (Doca salt) exposed to EMBM showed very significant differences between all groups. This is evidenced by the p value analysis that is <0.05, namely <0.001 so that it can be concluded that EMBM can reduce MDA levels in rats Hypertension. This effect is controlled by EMBM at a dose of 50 mg / KgBB which is the optimum dose in reducing pulmonarymalondialdehyd. Keywords : Hypertension, Mango mistletoe, MDA ABSTRAK Hipertensi merupakan penyakit kronik yang paling kerap ditemukan di masyarakat. Hipertensi berkaitan dengan peningkatan produksi radikal superoksida dan disfungsi endotel, yang menyebabkan stress oksidatif ditandai dengan meningkatnya kadar MDA. Benalu mangga mengandung senyawa metabolic sekunder seperti flavanoid yang berperan sebagai antioksidan alami. Penggunaan antioksidan dari benalu mangga menjadi salah satu alternatif untuk menetralisir terjadinya peningkatan MDA dalam tubuh dan menetralkan radikal bebas. Penelitian ini bertujuan untuk mengetahui kadar MDA pada tikus hipertensi (DOCA-Garam) yang dipapar Ekstrak Metanolik Benalu Mangga (EMBM) selama 14 hari. Penelitian ini menggunakan metode true eksperimental design dengan Rancangan Acak Lengkap pada 50 ekor tikus wistar jantan, dibedakan menjadi 5 perlakuan yaitru control (-), control (+), perlakuan 1 dosis 50 mg/KgBB, perlakuan 2 dosis 100 mg/KgBB dan perlakuan 3 dosis 200 mg/KgBB. Setiap perlakuan terdapat 5 kali ulangan. Analisis data menggunakan uji ANOVA one way dan post hoc yaitu JAMOVI dengan versi 1.1.9.0 yang digunakan untuk mengetahui perbedaan kadar MDA paru antar kelompok dan pulmonarymalondialdehyde (MDA) dianalisis dengan spektrofotometri. Hasil penelitian ini menunjukan bahwa kadar MDA paru pada tikus hipertensi (Doca- Garam) yang dipapar EMBM menunjukan perbedaan yang sangat nyata antara semua perkelompok. hal ini dibuktikan dengan analisis p value yaitu <0,05 yaitu <0,001 sehingga dapat disimpulkan bahwa EMBM dapat menurunkan kadar MDA pada tikus. Hipertensi. Efek ini dikendalikan oleh EMBM dosis 50 mg/KgBB yang merupakan dosis optimum dalam menurunkan kadar MDA Paru. Kata Kunci: Hipertensi, Benalu Mangga, MDA
POTENTIAL OF ENDOFITING FUNGALE EXTRACT FROM THE LEAVES OF MANGO PARASITE (Dendrophthoe pentandra (L.) Miq) AS ANTIOXIDANTS Dewi Qurrot &#039;Aini; Nour Athiroh Abdoes Sjakoer; Nurul Jadid Mubarakati
J-PEN Borneo : Jurnal Ilmu Pertanian Vol 6, No 1 (2023)
Publisher : FAKULTAS PERTANIAN UNIVERSITAS BORNEO TARAKAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35334/jpen.v6i1.3548

Abstract

The importance of the presence of bioactive compounds that have the potential as antioxidants from various medicinal plants has become a topic that is often discussed by several researchers today. One of the higher-classification plants that potentially has antioxidant activity is the mango parasite (Dendrophthoe pentandra (L.) Miq), classified as a parasite of the Loranthaceae family. The use of specific endophytic fungi microbes from mango parasites of leaf tissue is expected to produce several bioactive compounds that act as antioxidants needed for large-scale production in a short time without excessive exploitation of nature. This primary research aims to determine the potential antioxidant activity of endophytic fungi extracts from the parasite of mango leaves Integrated Microbiology Laboratory and Halal Center of the Islamic University of Malang. Antioxidant testing using DPPH (2,2-diphenyl-1-picrylhydrazyl) free-radical capture of activity method. The results showed that KEDBM 1 (Aspergillus spp.) isolates had no potential antioxidant activity. While KEDBM 2 (Aspergillus spp.) isolate has the highest antioxidant potential with an IC50 value of 13.71 μg/ml and KEDBM 3 (Colletotrichum spp.) has a high potential as an antioxidant with IC50 of 36.29 μg/ml.Key words: antioxidant, mango balu, DPPH, endophyte
In Vitro Screening of Antibacterial Activity of Endophytic Mold Extract from Mango Mistletoe Leaves (Dendrophthoe pentandra (L.) miq) Nafisa Nafisa; Nour Athiroh Abdoes Sjakoer; Nurul Jadid Mubarakati
JSMARTech: Journal of Smart Bioprospecting and Technology Vol. 4 No. 2 (2023): JSMARTech Volume 4, No. 2, 2023
Publisher : JSMARTech

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jsmartech.2023.004.02.59

Abstract

Endophytic microbes live in plant tissues and can be extracted to obtain active compounds. One conserved endophytic microbes is endophytic mold, found in plant tissue systems, such as leaves, flowers, branches, and plant roots. The endophytic mold was obtained from the mango parasite (Dendrophthoe pentandra (L.) Miq), a parasitic plant that contains secondary metabolites. This study aimed to determine the antibacterial properties of the endophytic mold isolates extract from mango parasite leaves against Escherichia coli. This research used an experimental method with descriptive quantitative data analysis. The research began with the purification of endophytic mold isolates, production of bioactive compounds, extraction of bioactive compounds, and determination of antibacterial activity by disc diffusion method. The results obtained from this study included four isolates containing antibacterial compounds, including isolates DBM 1, DBM 2, DBM 3, and DBM 4. Extracts of the endophytic mold of mango parasite leaves showed quite good inhibition of the growth of Escherichia coli, with the results of measuring the diameter of the largest inhibition zone of 13.17 mm, which was produced by isolate DBM 1 at a concentration of 75 ppm. Based on the results of antibacterial activity tests on endophytic molds from the leaves of the mango parasite (Dendrophtoe pentandra (L.) Miq), isolates of endophytic fungi can be used as antibacterial agents in the medium renewable category.
Co-Authors Abdul Hamid A. Toha Adi Sofyan Ansori, Muhammad Agus Mohammad Hikam Ahmad Taufiq Aisyah Febria Damayanti Alik Maulidiyah Annisatul Anis Hakimah Ari Hayati Ari Hayati Arifiati, Shinta Arina Roikhana Asari, Devi Indrayani Fitri Aulanni'am Aulanni'am Aulanni'am, Aulanni'am Azis Mawardi Azis Mawardi Chintya Ayu Pertiwi Della Aljanna Savita Dewi Qurrot &#039;Aini Dewi, Atikah Nur Shabrina Razan Dyan Aprillia Susanti Eka Kumalasari Fradina, IntanTrixi Galuh Ayu Setya Sari Gatot Ciptadi Gatra Ervi Jayanti Gatra Ervi Jayanti Hakimah, Annisatul Anis Hasan Zayadi Hatif Khusnin Nida' Hikam, Agus Mohammad Husain Latuconsina Islami, Darajatun Islamya, Nur Afni Auli Ismatud Diniyah ISNAWATI Istirochah Pujiwati Januarista, Terra Janur Annisa Sajida Kamilah, Nahdhiyatun Kharisma, Viol Dhea Kurniasari, Yulia Lestari, Tengku Anggun M. Abdul Qodir Jailani Ma'ruf, Muhammad Maghfiroh, Faldha Laili Malia Anjani Moch Mustakim Moch Mustakim Muhammad Dailami, Muhammad Musaffak, Taufik Ridwan Muzayyan, Abdullah Rozzen Nabilah Miftachul Khoiriyah Nabilla Abidah Alfita Nafisa Nafisa Nia Novita Nurrohmah Nour Athiroh Abdoes Sjakoer Nur Cahya Kartika Slamet Nur Laily Azizah Nur Mufida Nur Mufida Nurrohmah, Nia Novita Nurul Humaidah Oktavia Rahayu Puspitarini Oktaviana, Nimas Ajeng Pinanti, Honesty Nurizza Pratiwi, Radita Intan Aisyah Radita Intan Aisyah Pratiwi Rafsanjani, Ramizard Rahayu Dwi Lestari Ramadhan, Majida Rasyadan Taufiq Probojati Rossa Martha Wulandari Rossa Martha Wulandari Saimul Laili Sama’ Iradat Tito Saputri, Syntia Diyah Hayu Ria Silvia, Putri Azizatul Siti Khoirun Ni’mah Siti Qurrotul Aini Sulis Setiawati Suroyya, Mariyam Sutiman B. Sumitro Sutiman Bambang Sumitro Syaiful Arifin Tengku Anggun Lestari Thiya Fathiyatul Fauziyah Tintrim Rahayu, Tintrim Ula, Erfa Navadiatul Umu Intan Kinasih Vikriansyah, Muchammad Faruq Vina Fitria Wulandari Waliyyul Ahdi Alhikami Widyananda, Muhammad Hermawan Yunani, Silvi