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All Journal Majalah Kedokteran Bandung JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) Dentino: Jurnal Kedokteran Gigi Berkala Kedokteran Dental Journal (Majalah Kedokteran Gigi) The Indonesian Biomedical Journal Journal of Dentomaxillofacial Science MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Majalah Patologi Indonesia Jurnal Respirasi (JR) Darmabakti : Junal Pengabdian dan Pemberdayaan Masyarakat Jurnal Pengabdian Masyarakat Formosa (JPMF) Indonesian Journal of Cancer Homeostasis: Jurnal Mahasiswa Pendidikan Dokter
Ika Kustiyah Oktaviyanti
Departemen Patologi Anatomi Fakultas Kedokteran, Universitas Lambung Mangkurat, Banjarmasin, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Other

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Journal : Berkala Kedokteran

 1   2 
Gambaran Derajat Infiltrasi Sel Radang Dan Infeksi Helicobacter Pylori Pada Biopsi Lambung Pasien Gastritis: Di RSUD Ulin Banjarmasin Tahun 2009-2011 Yulida, Erna; Oktaviyanti, Ika Kustiyah; Rosida, Lena
Jurnal Berkala Kedokteran Vol 9, No 1 (2013): April 2013
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i1.918

Abstract

ABSTRACT: Gastritis is a common gastrointestinal problem all over the world. In Indonesia, the prevalence of gastritis is high enough, it’s about 274.396 cases among 238.452.952 people. The aim of this research is to find out the type and level of inflammation and the infection Helicobacter pylori on gastritis patient in RSUD Ulin Banjarmasin during 2009-2011. The method uses descriptive research by emphasize on preparation of gastric biopsy to find the level of acute inflammation, chronic inflammation dan Helicobacter pylori’s infection based on Updated Sydney System from Endoscopy and Pathology Department. Data were classified by gender, age, and the level of severity. From 52 cases, acute inflammation is occurred in 35 patients with 29 patients (83%) mild, 5 patients (14%) moderate, 1 patient (3%) severe. Chronic inflammation is occurred in 51 patients with 2 patients (4%) mild, 14 patients (27%) moderate, and 35 patients (69%) severe. Helicobacter pylori’s infection is  occurred in 30 patients with 3 patients (10%) mild, 6 patients (20%) moderate, and 21 patients (70%) severe. Keywords : gastritis, acute inflammation, chronic inflammation, Helicobacter pylori ABSTRAK: Gastritis merupakan salah satu masalah kesehatan saluran pencernaan yang paling sering terjadi di dunia. Angka kejadian gastritis di Indonesia cukup tinggi, yaitu 274.396 kasus dari 238.452.952 jiwa penduduk. Tujuan penelitian ini adalah untuk mengetahui jenis dan derajat keparahan infiltrasi sel radang serta infeksi Helicobacter pylori pada pasien gastritis di RSUD Ulin Banjarmasin. Metode penelitian yang digunakan adalah penelitian deskriptif dengan mengumpulkan data tingkat inflamasi akut, kronis dan infeksi Helicobacter pylori berdasarkan Updated Sydney System dari Instalasi Endoskopi dan Instalasi Patologi Anatomi. Data dikelompokkan menurut jenis kelamin, usia, dan tingkat keparahan. Dari 52 preparat, ditemukan inflamasi akut terjadi pada 35 pasien dengan 29 pasien (83%) derajat ringan, 5 pasien (14%) derajat sedang, dan 1 pasien (3%) derajat berat. Inflamasi kronik terjadi pada 51 pasien dengan  2 pasien (4%) derajat ringan, 14 pasien (27%) derajat sedang, dan 35 pasien (69%) derajat berat. Sedangkan infeksi Helicobacter pylori terjadi pada 30 pasien dengan 3 pasien (10%) derajat ringan, 6 pasien (20%) sedang, dan 21 pasien (70%) derajat berat. Kata-kata Kunci: gastritis, inflamasi akut, inflamasi kronis, Helicobacter pylori
NILAI DIAGNOSTIK SKOR KLINIS DIBANDINGKAN DENGAN BIOPSI PATOLOGI ANATOMI DALAM MENDIAGNOSIS PASIEN KARSINOMA NASOFARING Rahmayanti, Dini Desviana; Oktaviyanti, Ika Kustiyah; Istiana, Istiana
Jurnal Berkala Kedokteran Vol 11, No 1 (2015): Februari 2015
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.188

Abstract

Nasopharyngeal malignancy is the most commonly found among head and neck malignancies. Generally, nasopharyngeal cancer, has a good prognosis if it is detected as soon as possible. It is very important to diagnose it earlier because survival rate can be longer if therapy is given early. This study aims to determine the diagnostic value of clinical scores compared with histopathology biopsy to diagnose nasopharyngeal carcinoma in patients of RSUD Ulin Banjarmasin in the period 2012-2014. Subjects of this study were patients of RSUD Ulin Banjarmasin Hospital which is suspected nasopharyngeal carcinoma, who have examined the clinical symptoms by history and physical examination, had been registered in the medical record, and had been examined with histopathology biopsy. Data of clinical examination and histopathology biopsy from each sampel were collected for clinical symptom scores were analyzed according to get sensitivity value, specifity value, positif predictive value, and negative predictive value.Total subject of this research was 30. In this study, a minimum clinical score to lead to a nasopharyngeal malignancy that if found clinical score of 4, with a sensitivity, specifity, positive predictive value , and negative predictive value of 75%, 83.33%, 94.74%, 45.45% respectively. Clinical characteristics have high sensitivity and specifity to diagnose nasopharyngeal carcinoma. Keywords: diagnostic value, clinical scores, nasopharyngeal carcinoma
HUBUNGAN REAKSI LIMFOSIT DENGAN DERAJAT KEGANASAN KANKER SERVIKS DI RSUD ULIN BANJARMASIN PERIODE JANUARI-DESEMBER 2013 Hanafi, Ahmad Marzuki Rifki; Oktaviyanti, Ika Kustiyah; Istiana, Istiana
Jurnal Berkala Kedokteran Vol 11, No 1 (2015): Februari 2015
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.184

Abstract

Cervix cancer is a malignancy in women at most 3rd in the world, which occurs in the cervix uteri. Etiologic factor of cervix cancer is infection with human papilloma virus (HPV). Lymphocyte very important role in eradicating cancer cells. However, cervix cancer mortality rates remain high, especially in poor differentiated grade. This may be related to the level of mixed lymphocyte reaction and depending on the status of the tumor grade. This study aimed to determine the correlation between lymphocyte reaction with tumor grade in patients with cervix cancer in RSUD Ulin Banjarmasin period from January to December 2013. The study design was observational analytic study with cross-sectional approach. The data were taken in the form of primary data in the form of checks degrees lymphocytes with a microscope. The population is all women who underwent histopathological examination in RSUD Ulin period from January to December 2013. The sample was taken by purposive sampling as many as 56 people who had met the inclusion criteria. The results showed that the incidence of cervix cancer well-differentiated at most that 25 cases (44%) and lymphocyte reaction that many are mild lymphocyte reaction as much as 33 cases (59%). Somersd test analysis in the study obtained value (aprox sig. = 0.761). These results indicate that there is no significant correlation between lymphocyte reaction with tumor grade cervix cancer in RSUD Ulin period from January to December 2013. Keywords: cervix cancer, tumor grade, lymphocyte reaction
MUTASI EGFR PADA PEMERIKSAAN SITOLOGI ADENOKARSINOMA PARU Oktaviyanti, Ika Kustiyah
Berkala Kedokteran Vol 11, No 2 (2015): September 2015
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i2.171

Abstract

The case of lung cancer increased lately. World Health Organization (WHO) include lung cancer as one of the major problems facing the world in this decade, as more than 1.1 million people died from the disease. In histopathology, lung cancer is divided into several types, one of which is Adenocarcinoma. Various therapies developed to improve survival in patients with lung cancer, and recently also developed a therapeutic gene targets, one of which is the anti-EGFR. However, this therapy needs to be examination of the EGFR gene mutation, because the anti-EGFR therapy would respond in patients with EGFR gene mutation. This study aims to see how the pattern of EGFR mutations, and their relation to age, sex, and smoking habits. Research samples taken from pleural fluid cytology or biopsy of the tumor with fine needle aspiration, then examined whether there is an EGFR mutation. In this study, obtained 38 samples of patients with Adenocarcinoma of the lung, where 34% of patients had mutations in the gene EGFR, which consisted of 7 patients had mutations deletion in exon 19, 1 patients with mutations in exon 21L86IQ, 4 patients experienced EGFR mutations in exons 21L858R, and contained 1 those patients who had mutations in two places, namely in exon 19 and exon 21L861Q. EGFR mutations are many in the age range 40-49 years, but there is no relationship between the age of the patient with the presence and absence of mutations in the EGFR gene. In this study there was no difference between men and women who have EGFR mutations, but women with lung adenocarcinoma more mutated in EGFR. On this study, patients who did not smoke more EGFR mutations (51%) compared to the active smoking (10%). Keywords: lung adenocarcinoma, EGFR mutations
DERAJAT INFILTRASI LIMFOSIT PADA PENDERITA KANKER KOLOREKTAL SUB-TIPE ADENOKARSINOMA Imaduddin, Muhammad Sahal; Oktaviyanti, Ika Kustiyah; Istiana, Istiana
Berkala Kedokteran Vol 11, No 2 (2015): September 2015
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i2.141

Abstract

Cancer is the second leading cause of death which contributes 13% of deaths from a total of 22% of deaths from non-communicable diseases in the world. One contributor to the number of cancer deaths in the world is colorectal cancer. The prognosis of colorectal cancer depend on the stage of cancer at time of diagnosis. However, the prognosis of colorectal cancer can also be determined by looking at the degree of infiltration of lymphocytes in cancer. The purpose of this research is to find out the degree of lymphocytes infiltration in patients with colorectal cancer in Laboratory of Anatomical Pathology Banjarmasin from January to December 2013. The method uses descriptive research by observing the colorectal cancer tissues were obtained from the Laboratory of Pathology Banjarmasin. From a study of 32 samples, found the degree of mild lymphocytic infiltration occurred in 12 patients (37.5%), moderate lymphocytic infiltration occurred in 12 patients (37.5%), and severe lymphocyte infiltration occurred in 8 patients (25%). From this study, found that there are differences in the degree of infiltration of lymphocytes in patients with colorectal cancer. Keywords: Colorectal Cancer, Lymphocyte Infiltration, Prognosis
NILAI DIAGNOSTIK SKOR KLINIS DIBANDINGKAN DENGAN BIOPSI PATOLOGI ANATOMI DALAM MENDIAGNOSIS PASIEN KARSINOMA NASOFARING Dini Desviana Rahmayanti; Ika Kustiyah Oktaviyanti; Istiana Istiana
Berkala Kedokteran Vol 11, No 1 (2015)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.739 KB) | DOI: 10.20527/jbk.v11i1.188

Abstract

Nasopharyngeal malignancy is the most commonly found among head and neck malignancies. Generally, nasopharyngeal cancer, has a good prognosis if it is detected as soon as possible. It is very important to diagnose it earlier because survival rate can be longer if therapy is given early. This study aims to determine the diagnostic value of clinical scores compared with histopathology biopsy to diagnose nasopharyngeal carcinoma in patients of RSUD Ulin Banjarmasin in the period 2012-2014. Subjects of this study were patients of RSUD Ulin Banjarmasin Hospital which is suspected nasopharyngeal carcinoma, who have examined the clinical symptoms by history and physical examination, had been registered in the medical record, and had been examined with histopathology biopsy. Data of clinical examination and histopathology biopsy from each sampel were collected for clinical symptom scores were analyzed according to get sensitivity value, specifity value, positif predictive value, and negative predictive value.Total subject of this research was 30. In this study, a minimum clinical score to lead to a nasopharyngeal malignancy that if found clinical score of 4, with a sensitivity, specifity, positive predictive value , and negative predictive value of 75%, 83.33%, 94.74%, 45.45% respectively. Clinical characteristics have high sensitivity and specifity to diagnose nasopharyngeal carcinoma. Keywords: diagnostic value, clinical scores, nasopharyngeal carcinoma
HUBUNGAN REAKSI LIMFOSIT DENGAN DERAJAT KEGANASAN KANKER SERVIKS DI RSUD ULIN BANJARMASIN PERIODE JANUARI-DESEMBER 2013 Ahmad Marzuki Rifki Hanafi; Ika Kustiyah Oktaviyanti; Istiana Istiana
Berkala Kedokteran Vol 11, No 1 (2015)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (304.027 KB) | DOI: 10.20527/jbk.v11i1.184

Abstract

Cervix cancer is a malignancy in women at most 3rd in the world, which occurs in the cervix uteri. Etiologic factor of cervix cancer is infection with human papilloma virus (HPV). Lymphocyte very important role in eradicating cancer cells. However, cervix cancer mortality rates remain high, especially in poor differentiated grade. This may be related to the level of mixed lymphocyte reaction and depending on the status of the tumor grade. This study aimed to determine the correlation between lymphocyte reaction with tumor grade in patients with cervix cancer in RSUD Ulin Banjarmasin period from January to December 2013. The study design was observational analytic study with cross-sectional approach. The data were taken in the form of primary data in the form of checks degrees lymphocytes with a microscope. The population is all women who underwent histopathological examination in RSUD Ulin period from January to December 2013. The sample was taken by purposive sampling as many as 56 people who had met the inclusion criteria. The results showed that the incidence of cervix cancer well-differentiated at most that 25 cases (44%) and lymphocyte reaction that many are mild lymphocyte reaction as much as 33 cases (59%). Somers'd test analysis in the study obtained value (aprox sig. = 0.761). These results indicate that there is no significant correlation between lymphocyte reaction with tumor grade cervix cancer in RSUD Ulin period from January to December 2013. Keywords: cervix cancer, tumor grade, lymphocyte reaction
MUTASI EGFR PADA PEMERIKSAAN SITOLOGI ADENOKARSINOMA PARU Ika Kustiyah Oktaviyanti
Berkala Kedokteran Vol 11, No 2 (2015)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.501 KB) | DOI: 10.20527/jbk.v11i2.171

Abstract

The case of lung cancer increased lately. World Health Organization (WHO) include lung cancer as one of the major problems facing the world in this decade, as more than 1.1 million people died from the disease. In histopathology, lung cancer is divided into several types, one of which is Adenocarcinoma. Various therapies developed to improve survival in patients with lung cancer, and recently also developed a therapeutic gene targets, one of which is the anti-EGFR. However, this therapy needs to be examination of the EGFR gene mutation, because the anti-EGFR therapy would respond in patients with EGFR gene mutation. This study aims to see how the pattern of EGFR mutations, and their relation to age, sex, and smoking habits. Research samples taken from pleural fluid cytology or biopsy of the tumor with fine needle aspiration, then examined whether there is an EGFR mutation. In this study, obtained 38 samples of patients with Adenocarcinoma of the lung, where 34% of patients had mutations in the gene EGFR, which consisted of 7 patients had mutations deletion in exon 19, 1 patients with mutations in exon 21L86IQ, 4 patients experienced EGFR mutations in exons 21L858R, and contained 1 those patients who had mutations in two places, namely in exon 19 and exon 21L861Q. EGFR mutations are many in the age range 40-49 years, but there is no relationship between the age of the patient with the presence and absence of mutations in the EGFR gene. In this study there was no difference between men and women who have EGFR mutations, but women with lung adenocarcinoma more mutated in EGFR. On this study, patients who did not smoke more EGFR mutations (51%) compared to the active smoking (10%). Keywords: lung adenocarcinoma, EGFR mutations
THE EFFECT OF LONG EXPOSURE OF UV RADIATION ON ERYTHEMA AND MELANIN INDEX Isnaini Isnaini; Ika Kustiyah Oktaviyanti; Eko Suhartono
Berkala Kedokteran Vol 18, No 1 (2022)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (307.725 KB) | DOI: 10.20527/jbk.v18i1.11829

Abstract

UV radiation are divided into 3, namely UV A (400 – 315 nm), UV B (315-280 nm), UV C (280 – 100 nm). UV C radiation have the greatest effect on skin damage compared to UV A and UV B. UV radiation can reach the earth's surface, that can cause burning of the skin with signs such as redness of the skin (erythema), pain, blistering and peeling of the skin. Until now there has been no research on the effect of long exposure of UV C radiation on the erythema and melanin index, so aim this research is know about the effect of long exposure of UV C radiation on the erythema and melanine index. This research was conducted by giving exposure to rat that had been shaved with variations in exposure time, namely 5 minutes, 10 minutes, 15 minutes and 20 minutes. The skin that has been exposed with UV radiation will be photographed for color analysis using a chromometer. The results showed that exposure of UV radiation for 10 minutes caused the greatest increase in the melanin and erythema index
Gambaran Derajat Infiltrasi Sel Radang Dan Infeksi Helicobacter Pylori Pada Biopsi Lambung Pasien Gastritis: Di RSUD Ulin Banjarmasin Tahun 2009-2011 Erna Yulida; Ika Kustiyah Oktaviyanti; Lena Rosida
Berkala Kedokteran Vol 9, No 1 (2013)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (520.147 KB) | DOI: 10.20527/jbk.v9i1.918

Abstract

ABSTRACT: Gastritis is a common gastrointestinal problem all over the world. In Indonesia, the prevalence of gastritis is high enough, it’s about 274.396 cases among 238.452.952 people. The aim of this research is to find out the type and level of inflammation and the infection Helicobacter pylori on gastritis patient in RSUD Ulin Banjarmasin during 2009-2011. The method uses descriptive research by emphasize on preparation of gastric biopsy to find the level of acute inflammation, chronic inflammation dan Helicobacter pylori’s infection based on Updated Sydney System from Endoscopy and Pathology Department. Data were classified by gender, age, and the level of severity. From 52 cases, acute inflammation is occurred in 35 patients with 29 patients (83%) mild, 5 patients (14%) moderate, 1 patient (3%) severe. Chronic inflammation is occurred in 51 patients with 2 patients (4%) mild, 14 patients (27%) moderate, and 35 patients (69%) severe. Helicobacter pylori’s infection is  occurred in 30 patients with 3 patients (10%) mild, 6 patients (20%) moderate, and 21 patients (70%) severe. Keywords : gastritis, acute inflammation, chronic inflammation, Helicobacter pylori ABSTRAK: Gastritis merupakan salah satu masalah kesehatan saluran pencernaan yang paling sering terjadi di dunia. Angka kejadian gastritis di Indonesia cukup tinggi, yaitu 274.396 kasus dari 238.452.952 jiwa penduduk. Tujuan penelitian ini adalah untuk mengetahui jenis dan derajat keparahan infiltrasi sel radang serta infeksi Helicobacter pylori pada pasien gastritis di RSUD Ulin Banjarmasin. Metode penelitian yang digunakan adalah penelitian deskriptif dengan mengumpulkan data tingkat inflamasi akut, kronis dan infeksi Helicobacter pylori berdasarkan Updated Sydney System dari Instalasi Endoskopi dan Instalasi Patologi Anatomi. Data dikelompokkan menurut jenis kelamin, usia, dan tingkat keparahan. Dari 52 preparat, ditemukan inflamasi akut terjadi pada 35 pasien dengan 29 pasien (83%) derajat ringan, 5 pasien (14%) derajat sedang, dan 1 pasien (3%) derajat berat. Inflamasi kronik terjadi pada 51 pasien dengan  2 pasien (4%) derajat ringan, 14 pasien (27%) derajat sedang, dan 35 pasien (69%) derajat berat. Sedangkan infeksi Helicobacter pylori terjadi pada 30 pasien dengan 3 pasien (10%) derajat ringan, 6 pasien (20%) sedang, dan 21 pasien (70%) derajat berat. Kata-kata Kunci: gastritis, inflamasi akut, inflamasi kronis, Helicobacter pylori
Co-Authors AA Sudharmawan, AA Achmad Rudijanto Agung Ary Wibowo Agung Ary Wibowo Agung Ary Wibowo Agung Ary Wibowo, Agung Ary Ahmad Marzuki Rifki Hanafi Ahmad Marzuki Rifki Hanafi, Ahmad Marzuki Rifki Al Hasani, Siti Atthahirah Alfi Yasmina Ali Assagaf Alifah Nadia Ambarita, Winona Vida Vita Nathania Anak Agung Istri Sri Wiadnyani Arganita, Fidya Rahmadhany Ariska Endariantari Asnawati Asnawati Asnawati Asnawati Brian Hansen Efraim Sitompul Budiwinata, Winardi Desi Rahmawaty Dewi Nurdiana Diani, Holly Dini Desviana Rahmayanti Dini Desviana Rahmayanti, Dini Desviana Djanggan Sargowo Djanggan Sargowo Eka Yudha Rahman Eka Yudha Rahman Eka Yudha Rahman Eko Suhartono Eko Suhartono Erna Yulida Fahrina Ulfah Fatmathalia Ranti Gading Aurora Puspita Kencana Hafidza, Fadhil Haryati Haryati Hasfira, Fairuz Izdihar Hendra Sutapa Hendra Sutapa Heni Pujiastuti Hery Poerwosusanta Hery Poerwosusanta Hidayat Sujuti Hilda Ayu Setyawati Hilda Ayu Setyawati, Hilda Ayu Ida Yuliana Ida Yuliana Ira Nurrasyidah Irfan Maulana Irfan Maulana, Irfan Isa Ansori Isa, Mohamad Isnaini Isnaini Istiana Istiana Istiana Istiana Juliana, Adies Kanessha Winola Sunata Karyono Mintaroem Karyono Mintarum Khairini Putri Khatimah, Husnul Kusumawardhani, Erna Lena Rosida Lena Rosida Lena Rosida Madargerong, Vincentius Adrian Maharani Laillyza Apriasari Maria Ulfah Mohammad Aris Widodo Muhammad Abianovan Ramadhan Muhammad Ajib Nuzula Muhammad Ali Faisal Muhammad Rizki Syabana Muhammad Sahal Imaduddin Muhammad Sahal Imaduddin, Muhammad Sahal Muthmainah, Noor Nazwa Salsabila Hadni Nikmah, Elok Hikmatun Nurdiana Dewi Nurrafi Aliya Khasanah Oscar Tri Joko Putra Prenggono, Muhamad Darwin Priyono, Sasongko Hadi Rahmiati Rahmiati Rosmitha Monikayani Salma Nurul Ahyati Sasongko Hadi Priyono Sukses Hadi Syafa’ah, Irmi Tenri Ashari Wanahari Triawanti Triawanti Triawanti Ulfah, Fahrina Wahyuni, Dina Widodo, Firman Aprilianto Widya Noor Haliza Widya Shoffa Rosyida Widya Wulan Fitri Winardi Budiwinata Winardi Budiwinata Zakia, Sukma Dina