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All Journal Indonesian Journal of Forestry Research Jurnal Penelitian Hasil Hutan Al-Kimia Jurnal Ilmu dan Teknologi Kayu Tropis PERENNIAL Jurnal Penelitian Hasil Hutan Jurnal Sylva Lestari Makara Journal of Technology Indonesian Journal of Forestry Research Jurnal Penelitian Hasil Hutan
Gustan Pari
Pusat Litbang Hasil Hutan, Badan Litbang dan Inovasi, Kementerian Lingkungan Hidup dan Kehutanan (Ministry of Environtment and Forestry of Indonesia)
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Earth & Planetary Sciences Electrical & Electronics Engineering Energy Engineering Environmental Science Materials Science & Nanotechnology Mechanical Engineering

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THE EFFECTIVENESS OF GLUCOMANNAN AND NANO ACTIVATED-CARBON AS HYPERCHOLESTEROL-LOWERING AGENTS Pasaribu, Gunawan Trisandi; Waluyo, Totok K.; Pari, Gustan; Hastuti, Novitri
Indonesian Journal of Forestry Research Vol. 7 No. 2 (2020): Indonesian Journal of Forestry Research
Publisher : Association of Indonesian Forestry and Environment Researchers and Technicians

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59465/ijfr.2020.7.2.155-164

Abstract

Porang (konjac) plants have long been used as a food source and traditional medicine. Glucomannan derived from porang has been utilised for various uses such as antidiabetic and antihypercholesterolemia agent. This paper studies the mixture of porang flour and nano activated-carbon and its effect on the cholesterol activity of rats. The mixture of porang and activated carbon were subjected to test for male Sprague Dawley rats to test the antihypercholesterolemia activity. The result showed that concerted anticholesterol activity of porang and nano activated-carbon revealed the cholesterol level decreases in rat's blood. However, the different treatments of unleached and leached porang either leached porang and nano activated-carbon applied in the experiments showed that the levels of cholesterol decrease were slightly different (16–18%). Low glucomannan content as the alleged anticholesterol agent was regarded quite effective in lowering the cholesterol level in rat's blood and comparable with those of simvastatin which achieved 18% reduction. Therefore, it indicates potential utilisation as a functional food for a cholesterol-lowering agent. The involvement of activated carbon in the alleged anticholesterol agent (leached porang flour) did little in enhancing the cholesterol level decrease in rat's blood. The glucomannan in both leached porang flour and leached porang flour + nano activated-carbon shows potential utilisation as an anticholesterol agent. Yet, raw (unleached) porang is prospectively potential as a functional food for cholesterol-lowering.
Co-Authors A.A. Ketut Agung Cahyawan W Akhiruddin Maddu Akhirudin Maddu Al Amady, M. Rawa Amal Andi Detti Yunianti Andianto Arya Sokanandi Buchari Buchari Diah Tri Widayati Dian Anggraini Indrawan Djeni Hendra Dodik Ridho Nurrochmat Efrida Basri Farly Reynol Tumimomor Gunawan Pasaribu Gunawan Santosa Gunawan Trisandi Pasaribu, Gunawan Trisandi Gusmailina Gusmailina Hadiyane, Anne Han Roliadi Hardjanto Hery Widijanto I Nyoman Jaya Wistara Imam Wahyudi Indrawan, Imam Wahyudi Imas Aisyah Jasni Jasni Karliati, Tati Krisdianto Sugiyanto Kurnia Sofyan Mahpudin Mahpudin Mamat Rachmat Marta Dinata Masato Yoshida, Masato Mody Lempang Mohamad Iqbal Mohammad WIJAYA Muji Harsini Navila, Aviva Novitri Hastuti, Novitri Nurul Aprilia, Nurul Nuryati Juli Prayogo, Yanico Hadi Ridwan A. Pasaribu, Ridwan A. Rina Novia Yanti Rita Kartika Sari Rossi Margareth Tampubolon Rumidatul, Alfi S, Suhasman Saepuloh Saepuloh Santiyo Wibowo Saptadi DARMAWAN Siruru, Herman Sri Komarayati Sukadaryati Sukadaryati SURYANTI T A Prayitno, T A Teddi Heryanto Totok K Waluyo Totok K. Waluyo, Totok K. Totok Kartono Waluyo, Totok Kartono Wasrin Syafi, Wasrin Wasrin Syafii