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All Journal HAYATI Journal of Biosciences Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Pengajaran MIPA Jurnal Pendidikan Indonesia Formica Education Online Journal of Mathematical and Fundamental Sciences Jurnal Pendidikan Biologi Indonesia Jurnal Penelitian dan Pembelajaran IPA Science and Technology Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) Pedagonal : Jurnal Ilmiah Pendidikan Bioscientist : Jurnal Ilmiah Biologi These proceedings represent the work of researchers participating in The International Conference on Elementary Education (ICEE) which is being hosted by the Elementary Education Study Programme School of Postgraduate Studies, Universitas Pendidikan Proceeding Biology Education Conference Makara Journal of Science Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) Applied Environmental Science Asian Journal of Toxicology, Environmental, and Occupational Health Jurnal Bisnis Kehutanan dan Lingkungan Jurnal Inovasi Pangan dan Gizi Jurnal Pendidikan MIPA Sasambo: Jurnal Abdimas (Journal of Community Service)
Didik Priyandoko
Universitas Pendidikan Indonesia
Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Phytochemical Analysis, Antioxidant Activity, and Cytotoxic Effects of Physalis angulata and Moringa oleifera Leaf Extracts on Cancer and Normal Cells In Vitro Priyandoko, Didik; Widowati, Wahyu; Sholihah, Ika Adhani; Zahira, Nurul Zahra; Bangun, Adityana Arta; Kusdianti, Kusdianti; Hernawati, Hernawati; Surakusumah, Wahyu; Juansah, Rahadian Deden
Makara Journal of Science Vol. 29, No. 1
Publisher : UI Scholars Hub

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Abstract

Physalis angulata and Moringa oleifera have long been the key ingredients of traditional medicine. This study aimed to obtain the metabolite profiles of the ethanolic leaf extracts of P. angulata (ELP) and M. oleifera (ELM), evaluate their antioxidant activity, and assess their toxicity against normal and cancer cells. The leaves were sourced from Balittro, West Java. The extraction used 70% ethanol and continued for 3 days. The metabolites were identified using Gas Chromatography-Mass Spectrometry (GC-MS), antioxidant activity was ascertained via the DPPH assay, and cytotoxicity was evaluated employing the PrestoBlue assay. GC-MS identified 23 compounds in ELP and 15 in ELM. The DPPH assay showed that ELM, ELP, or their combination exhibited marked antioxidant activity, with inhibition ranging from 50% to 90%. The toxicity assay against MCF-7 cancer cells demonstrated that ELP at 1,500 µg/mL and ELM at 1,200 µg/mL induced cytotoxicity. The ELP + ELM formulation exhibited stronger cytotoxic effects than the positive control. In contrast, ELM or ELP did not induce toxicity in normal CV-1 cells and, stimulated viability com-pared to the control. Thus, the phytochemical contents of ELM and ELP exhibited enhanced antioxidant activity, in-duced toxicity in cancer cells, and were safe for normal cells.
Implementasi Problem Based Learning untuk Meningkatkan Habits Of Mind, Emotional Intelligence, dan Penguasaan Konsep Siswa Daryanes, Febblina; Sriyati, Siti; Priyandoko, Didik
Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) 2016: Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek)
Publisher : Universitas Muhammadiyah Surakarta

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Kemampuan Habits of Mind, Emotional Intelligence, dan penguasaan konsep dapat dilatih, dikembangkan, dan ditingkatkan melalui suatu model pembelajaran. Penelitian ini bertujuan untuk mengetahui peningkatan Habits of Mind, Emotional Intelligence, dan penguasaan konsep siswa SMA melalui implementasi Problem Based Learning. Metode yang digunakan dalam penelitian ini adalah weak experiment dengan desain penelitian one-group pretestposttest yang dilakukan di kelas XI IPA 1 SMAN 1 Rengat Riau. Pengumpulan data dilakukan melalui angket Habits of Mind awal dan akhir, angket Emotional Intelligence awal dan akhir, soal pretest dan posttest materi sistem ekskresi dan sistem saraf. Analisis data penelitian menggunakan nilai normalisasi gain. Hasil penelitian menunjukkan bahwa kemampuan Habits of Mind siswa setelah implementasi Problem Based Learning mengalami peningkatan dengan N-gain sebesar 0,53 berada dalam kategori sedang. Sejalan dengan itu, kemampuan Emotional Intelligence siswa juga mengalami peningkatan dengan N-gain sebesar 0,33 berada dalam kategori sedang. Kemampuan penguasaan konsep siswa pada materi sistem ekskresi mengalami peningkatan dengan N-gain sebesar 0,66 berada dalam kategori sedang, sedangkan pada materi sistem saraf mengalami peningkatan dengan N-gain sebesar 0,84 berada dalam kategori tinggi. Dapat disimpulkan bahwa implementasi Problem Based Learning dapat meningkatkan kemampuan Habits of Mind, Emotional Intelligence, dan penguasaan konsep siswa. Peningkatan kemampuan Habits of Mind, Emotional Intelligence, dan penguasaan konsep siswa di atas nilai standar 0,31 (N-gain sedang).
Upaya Remediasi Miskonsepsi Pada Materi Sel Menggunakan Model Pembelajaran Think Talk Write Muzakki, Naufal Ahmad; Diana, Sariwulan; Priyandoko, Didik
Jurnal Penelitian Pendidikan IPA Vol 9 No 12 (2023): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i12.3470

Abstract

In cell material, many concepts are abstract and can cause students to experience difficulties in understanding them. Every concept in biology learning is interconnected so that every concept that is built can influence the formation of the next concept. However, often students' initial concepts are misconceptions, namely the concepts possessed by students conflict with the concepts raised by experts. A good learning experience is needed so that students can understand the concept correctly. One learning model that provides a learning experience to discover and understand concepts is the Think Talk Write learning model. The purpose of this research is to remediate misconceptions about cell material by using the Think Talk Write learning model. This study used an experimental method with the type of pre-experimental research and one-group pretest-posttest research design. The subjects in this study were students of class XI IPA at SMA Muhammadiyah 5 Rancaekek consisting of 36 students. Based on the results of data processing, it was found that misconceptions in the pretest resulted in 12.78% and in the posttest it decreased to 6.25%. So it can be concluded that the Think Talk Write learning model can reduce students' misconceptions about cell material.
Pengembangan E-Modul untuk Melatih Kemampuan Literasi Membaca Peserta Didik SMA Faidah, Siti Tahany Rifa; Sriyati, Siti; Priyandoko, Didik
Jurnal Penelitian Pendidikan IPA Vol 9 No 8 (2023): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i8.3763

Abstract

This study aims to develop an E-Module to train high school students' reading literacy skills. The e-module was designed using Canva-assisted power point and saved in power point show. The power point show is then sent via WhatsApp for students to use. This research uses the development method with the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation) according to. The implementation phase uses a pretest – posttest non-equivalent control group design to obtain information about the effect the developed E-Module. This research was conducted at a public high school in Cimahi City, West Java Province in February-March 2023. The sample for this study was taken by convenience sampling , namely 30 students from class XI IPA 1 as the experimental class and 30 students from class XI IPA 2 as the experimental class. control. The instruments and data collection techniques used in this study were the due diligence validation sheets, readability tests and reading literacy skills tests. The results showed that the feasibility test for the developed E-module showed very feasible criteria, the readability test showed a result of 80% with easy-to-understand criteria and the development of this E-module could increase reading literacy skills by 0.7 with high criteria on the indicator of finding information, 0.8 with high criteria on indicators of interpretation and integration and a score of 1 with high criteria on evaluating and reflecting indicators.
Co-Authors Adi Rahmat Agustin, Dhini Ahmad Faried Alexandro, Garry Alyasa, Rahadian Rasyid Anisa Noor Aulia Annaba, Aziz Any Aryani Azis, Rizal Azmi, Haibah Azzania Fibriani Bangun, Adityana Arta Dadang Machmudin Deocaris, Custer C. Diah - Kusumawaty Diah Puspitasari Dina Karina Islami Dzikrina, Hanina Eka Yudha Rahman Eliya Mei Sisri Faidah, Siti Tahany Rifa Fauziyah, Lathifah Zahra Febblina Daryanes Fitriani Nurpratiwi Susanto Fransisca Sudargo Gina Angelina Hadiprasetyo, Dhanar Septyawan Handayanie, Yunni Hanna Sari Widya Kusuma Harry Murti Hernawati Hernawati Hodijah, Siti Romlah Noer Janitra, Fikrah Jeffrey ., Jeffrey Juansah, Rahadian Deden Kartika Kaul, Sunil C. Kusdianti Kusdianti Kusdianti Leonita, Lastri Mamat Arohman Mrs Sariwulan Diana Muzakki, Naufal Ahmad Nainggolan, Ita Margaretha Nashi Widodo Naufal Ahmad Muzakki Naufal Ahmad Muzakki Naufal Ahmad Muzakki Nia Kania Nia Nurdiani Norine, Jennifer Nurul Faridah, Nurul Nuryani Rustaman Putri Yunitha Wardiny Qlintang, Sandy Rahmat, Adi RAHMAT, DENI Rahmi, Annisa Salsyabila Rizal Rizal S. Saefudin Sa'diatul Fuadiyah Sabrina, Adilah Hafizha Nur Saefudin Saefudin Sajidah, Salmaa Nabiilah Santoso, Fadhila Zahra Sari, Prima Mutia Sholihah, Ika Adhani Sholihah, Uswatun Siti Sriyati Suhara, Nur Fajriyah Surtikanti Hertien Koosbandiah, Surtikanti Sylva Sagita Teresa Liliana Wargasetia Topik Hidayat Triharsiwi, Dwi Nur TRINA EKAWATI TALLEI Try Kurniawan Vinna Kurniawati Sugiaman, Vinna Kurniawati Wadhwa, Renu Wahyu Surakusumah Wahyu Widowati WAHYU WIDOWATI Wahyudin, Wahyudin Wawan Setiawan Wawan Setiawan Yayan Sanjaya Yunita, Shella Yusuf Hilmi Adisendjaja Zahira, Nurul Zahra Zahra, Cheryl Dwi Nur