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All Journal Jurnal Kedokteran Brawijaya Berkala Ilmu Kesehatan Kulit dan Kelamin The Indonesian Biomedical Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Amerta Nutrition PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat J-Dinamika: Jurnal Pengabdian Kepada Masyarakat JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Majalah Biomorfologi (Biomorphology Journal) Jurnal Layanan Masyarakat (Journal of Public Service) Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology Indonesian Andrology and Biomedical Journal Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing)
Nurina Hasanatuludhhiyah
Department Of Anatomy, Histology And Pharmacology, Faculty Of Medicine, Universitas Airlangga, Surabaya, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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The effect of omega-3 fatty acids and vitamin E supplementation on lipid profiles and inflammatory markers in hemodialysis patients: A systematic review of current literature Meliana, Ahila; Afizah, Ameilia Anastasya Rahma; Hasanatuludhhiyah, Nurina
Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) VOLUME 11 ISSUE 1, 2023
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/ijnd.2023.11(1).1-10

Abstract

ABSTRAK Latar Belakang: Kebutuhan terapi hemodialisis (HD) masih terus berkembang. Di Indonesia, HD mewakili 82% dari pelayanan cuci darah di Puskesmas Indonesia. Namun, HD menyebabkan peningkatan penanda inflamasi serta perubahan profil lipid. Kombinasi vitamin E dan asam lemak omega-3 dapat membantu mengurangi indikator inflamasi dan meningkatkan profil lipid.Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh co-suplementasi vitamin E dan omega-3 terhadap profil lipid dan indikator inflamasi.Metode: Penelitian ini dilakukan di PubMed dan Google Scholar untuk mencari artikel-artikel secara sistematis, Kriteria inklusi yang digunakan adalah artikel bahasa Inggris dengan uji coba terkontrol acak (RCT) dan uji coba terkontrol (CT) yang menyelidiki efek vitamin E dan omega-3 pada profil lipid dan penanda inflamasi pasien hemodialisis. Semua artikel harus diterbitkan antara September 2013 - September 2022. AM dan AA melakukan seluruh proses penelitian sebagai reviewer dan seluruh ketidaksetujuan diselesaikan bersama NH sebagai penulis ketiga.Hasil: 1020 studi diidentifikasi dari database dan 12 artikel terpilih berdasarkan kriteria inklusi. Asam lemak omega-3 meningkatkan profil lipid, seperti kolesterol, LDL, HDL, dan trigliserida. Namun, studi ini hanya menemukan satu penelitian tentang efek vitamin E pada profil lipid. Asam lemak Omega-3 dan suplementasi vitamin E tidak memiliki efek signifikan pada penanda inflamasi, tetapi dampak suplementasi vitamin E pada tingkat IL-6 telah dilaporkan.Kesimpulan: Co-suplementasi Omega-3 dan vitamin E berpengaruh pada penurunan level indikator inflamasi dan profil lipid pasien hemodialisis. Kami merekomendasikan bahwa studi berikutnya harus berfokus pada penelitian uji klinis mengenai pengaruh suplementasi kombinasi ini terhadap indikator inflamasi dan profil lipid pasien hemodialisis. KATA KUNCI: hemodialisis; indikator inflamasi; omega-3; profil lipid; vitamin E ABSTRACTBackground: Hemodialysis therapy (HD) demands is still growing. In Indonesia, HD represents 82% of dialysis services in Indonesian health centers. However, HD causes an increase in inflammatory markers as well as lipid profile changes. The combination of vitamin E and omega-3 fatty acids can assist to decrease inflammatory indicators and enhance lipid profiles.Objectives: This study aims to investigate the effect of co-supplementation of vitamin E and omega-3 on lipid profiles and indicators of inflammation.Methods: This study was conducted on PubMed and Google Scholar to search articles systematically. The inclusion criteria used were English articles of randomized controlled trials (RCTs) and controlled trials (CT) that investigated the effects of vitamin E and omega-3 on lipid profiles and inflammatory markers of hemodialysis patients. All articles must be published between September 2013 - September 2022. AM and AA conducted the entire research process as reviewers and all disagreements were finalized with NH as a third author.Results: 1020 studies were identified from databases. Afterward, this study included 12 articles based on the inclusion criteria. Omega-3 fatty acids improve lipid profiles, such as cholesterol, LDL, HDL, and triglyceride. While we only found a single study about the effect of vitamin E on lipid profile. Furthermore, omega-3 fatty acids and vitamin E supplementation have no significant effect on inflammatory markers, but the impact of vitamin E supplementation on IL-6 levels was reported.Conclusions: Co-supplementation of omega-3 and vitamin E decrease levels of inflammatory indicators and lipid profiles in hemodialysis patients. We recommend that future studies should focus on clinical trials to investigate the effect of this co-supplementation on lipid profiles and inflammatory markers of hemodialysis patients. KEYWORD: hemodialysis; inflammatory markers; lipid profiles; omega-3, vitamin E
Mental Health Status and Literacy of Adolescent in Rural Area of Mojokerto, East Java, Indonesia Ardana, Arin Aurilia; d'Arqom, Annette; Puteri, Fira Adilah; Indiastuti, Danti Nur; Nasution, Mhd Zamal; Hasanatuludhhiyah, Nurina; Qorib, Mohammad Fathul; Setiawati, Yuani; Junaidah Yusof
Jurnal Psikiatri Surabaya Vol. 14 No. 2 (2025): November
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v14i2.64237

Abstract

Introduction: Adolescence is a crucial period for the development of mental health. Enhancing mental health literacy can reduce stigma and support early intervention and treatment. This study aims to examine the mental health status and mental health literacy among middle and late adolescents in a rural area of Mojokerto District, East Java, Indonesia. Methods: A total of 81 high school students from Mojokerto District participated in the study. The Depression Anxiety Stress Scale – Youth version (DASS-Y) was used to assess symptoms of depression, anxiety, and stress. Mental health literacy was measured using the Adolescent Mental Health Literacy Questionnaire (AMHL). The validity of the AMHL was tested on 30 students using Pearson correlation. Descriptive statistics were used to analyze the prevalence of mental health conditions and levels of mental health literacy. Inferential statistics were applied to explore associations between mental health status, literacy, and sociodemographic variables. Results: The results showed that 53% of students experienced symptoms of mental health problems. While most students demonstrated moderate to satisfactory mental health literacy, significant gaps remain. Enhancing literacy may help reduce stigma and improve knowledge and attitudes toward mental health. Sociodemographic factors and mental health literacy showed limited influence on mental health status. However, sex was significantly associated with both mental health literacy and mental health status (p = 0.016 and p = 0.032, respectively). Conclusion: Mental health during adolescence significantly influences adult well-being. Improving adolescent mental health literacy is crucial for early recognition, stigma reduction, and better access to mental health care.
Co-Authors Abdul Khairul Rizki Purba Mustofa Indwiani Astuti Achmad Basori Achmad Basori Afif Nurul Hidayati Afizah, Ameilia Anastasya Rahma Akbar Kurniawan, Mohammad Alissa Qodrunnada Anastasia K. Sikora Annete D'Arqom Annette d’Arqom, Annette Ardana, Arin Aurilia Arifa Mustika Arsyi, Danial Habri atika Brilianti, Natasya Nurvita Cahyo Wibisono Nugroho Deandra Maharani Widiatmaja Dian Fitria Djoko Santoso Eddy Bagus Wasito Farabi, Moh. Reza Farapti Farapti Fatimah, Nurmawati Haerani Rasyid Heny Arwati Hermina Novida, Hermina Ika Nindya Kadariswantiningsih Ilham Rahmanto Indiastuti, Danti Nur Junaidah Yusof Kawilarang, Arthur Pohan Kusuma Eko Purwantari Kusumadewi, Salsabila Rahma Maftuchah Maftuchah Margaretha Nathania Maulana Antiyan Empitu Maulana Muhtadin Suryansyah Meliana, Ahila Meliana, Ahila Melida Agustina Mhd Zamal Nasution Mochammad Amin MOCHAMMAD THAHA Mohammad Yusuf Alsagaff Muhammad Nuh Ihsan Muhammad Sholikhuddin Nafi’ Muhammad Sholikhuddin Nafi’ Muhammad Zulkifly Tasman Mukhoirotin Mukhoirotin Nariswari, Rachma Putri Nily Sulistyorini Paramitha, Nabilah Permana, Putu Bagus Dharma Prabowo, Gwenny Ichsan Pratiwi, Octaviana Galuh Prijati Sri Irawati Prijati Sri Irawati Purba, Abdul Khairul Rizki Puspa Wardhani Puspa Wardhani Puteri, Agnes Ilene Suprapto Puteri, Fira Adilah Putu Bagus Dharma Permana Qorib, Mohammad Fathul Raden Mohamad Herdian Bhakti Rahman, Beny Aji Ifaudi Rasyidah, Amira Farah Ratnani, Arifian Hardi Putri Rieza Rizqi Alda Rizki Isnantono Prabowo Rodia Amanata Rofiq Sakina Sakina, Sakina Sangidatul Imro'ah Sawitri, Brihastami Suhartati Suhartati Suhartati Susila, I Made Dwi Yudiartana Putra Toyib, Muchammad Tri Hartini Yuliawati Tri Hartini Yuliawati Viskasari P. Kalanjati Visuddho , Visuddho Visuddho Visuddho Willy Sandhika Winarno, Didik Dwi Yuani Setiawati Yudhono, Anggit Satriyo Yulianti, Erikavitri Yulis Setiya Dewi Yusuke Suzuki Zaky El Hakim