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Dampak β-Hidroksibutirat (BHB) pada Tubuh Manusia: Tinjauan tentang Badan Keton, Sumber, Metabolisme, Manfaat Kesehatan, dan Kerugian Potensial Muhammad Raka Tresna; Hadi Sudarjat
Jurnal Sehat Mandiri Vol 19 No 2 (2024): Jurnal Sehat Mandiri, Volume 19 Nomor 2 Desember 2024
Publisher : Poltekkes Kemenkes Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33761/jsm.v20i1.1583

Abstract

Ketone bodies are small lipid-derived molecules that have a function as a circulating energy source for tissues when in glucose deficiency conditions. When glucose in glycogen stores is largely depleted, fatty acid breakdown will occur in the mitochondria through β-oxidation which produces ATP and acetyl-CoA. Fatty acid breakdown in the liver will produce ketone bodies, which then reduce acetoacetate to β-hydroxybutyrate (BHB) that serves as alternative energy. The purpose of this study is to determine the impact of β-hydroxybutyrate (BHB) used in the form of supplements on the body and as an alternative energy source, is expected to provide insight into the impact of β-hydroxybutyrate (BHB) on the body. The method used is a qualitative method using narrative literature review on 5 articles that have been analyzed, and meet the eligibility of 2306 articles found on PubMed between 2014 and 2024. The results of this study β-hydroxybutyrate (BHB) has good effectiveness and safety for the body and is good as an alternative energy source, and has no negative impact on health. The conclusion of this study is that supplementing the body with ketones supports the effectiveness of ketone bodies to provide alternative energy and better resilience. It is recommended that researchers who will take the title of research on β-hydroxybutyrate (BHB) to see the potential given to health and its usefulness in having an impact on the body.
Efektivitas Produk Herbal Antijamur untuk Terapi Ketombe (Pityarisis capitis): Literature Review dan Analisis Bibliometrik Esti Syahrin; Hadi Sudarjat; Rachel Noveriachristie Balapadang
Jurnal Sehat Mandiri Vol 20 No 1 (2025): Jurnal Sehat Mandiri, Volume 20 Nomor 1 Juni 2025
Publisher : Poltekkes Kemenkes Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33761/jsm.v20i1.1802

Abstract

Dandruff (Pityriasis capitis) is a skin health problem caused by fungal growth on the scalp, increased production of oil glands (sebum) excessively. Current advances in science and technology have led to the development of herbal plant research to be used as antifungal herbal products in overcoming dandruff. The purpose of this literature review is to review and summarize herbal plants that have the potential to inhibit the growth of fungi that cause dandruff, so that it is useful to be developed as further research. Article searches were conducted from February to May 2024 using the Publish or Perish reference manager (PoP) tool in the Google scholar database source which was then term mapped in the Vosviewer software. The results of original research journal publications related to dandruff published in the range of 2014 to 2024 were obtained as many as 12 journals. The conclusion obtained in this literature review is that secondary metabolite compounds contained in herbal plants have a potential fungal inhibition mechanism, so it is appropriate to be developed in future research and used as an antifungal herbal product to treat dandruff.
Pengaruh Konseling Apoteker Terhadap Kepatuhan Pasien Hipertensi: Literature Review: The Impact of Pharmacist Counseling on Hypertensive Patient Compliance: A Literature Review Triana Maudy Yulianti Surasa; Indah Laily Hilmi; Hadi Sudarjat; Fitri Oktaviani Nurdin
Jurnal Surya Medika (JSM) Vol. 11 No. 3 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i3.11949

Abstract

Hipertensi adalah kondisi kronis yang memerlukan terapi jangka panjang. Ketidakpatuhan pasien terhadap pengobatan sering menjadi penyebab kegagalan terapi. Konseling apoteker telah terbukti efektif dalam meningkatkan kepatuhan pasien hipertensi. Studi ini bertujuan untuk menganalisis dampak konseling apoteker terhadap kepatuhan pasien dalam pengobatan hipertensi. Metode yang digunakan adalah narrative review, di mana artikel-artikel yang relevan dari 10 tahun terakhir diambil dari Google Scholar. Hasil penelitian menunjukkan bahwa konseling apoteker berperan penting dalam meningkatkan kepatuhan pasien, di mana beberapa studi menunjukkan peningkatan signifikan dalam kepatuhan serta penurunan tekanan darah pasien yang mendapatkan konseling. Kesimpulan dari review ini adalah bahwa konseling apoteker memberikan dampak positif terhadap keberhasilan terapi hipertensi, dengan peningkatan kepatuhan dan kontrol tekanan darah yang lebih baik. Oleh karena itu, konseling apoteker sebaiknya menjadi bagian integral dalam manajemen hipertensi.
Faktor Psikologis dan Kualitas Hidup Pasien Penyakit Kronis: Tinjauan Literatur tentang Progresivitas Penyakit dan Dukungan Psikososial Muhammad Rizki Al Gibran; Dede Riyanto; Indah Laily Hilmi; Hadi Sudarjat
GUIDENA: Jurnal Ilmu Pendidikan, Psikologi, Bimbingan dan Konseling Vol. 16 No. 1 (2026)
Publisher : Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/gdn.v16i1.15043

Abstract

Chronic diseases often require long-term treatment and continuous self-management, yet patients with similar diagnoses may show different clinical outcomes and quality of life. These differences indicate that non-biological factors, particularly psychological conditions, play an important role in disease progression and patient well-being. Psychological risk factors such as stress, depression, and anxiety may worsen chronic disease outcomes, whereas protective factors such as optimism and positive expectations may support adaptive coping and improve quality of life. This literature review aimed to analyze recent scientific evidence on the role of psychological factors in the progression of chronic diseases and the quality of life of patients. A literature review was conducted by examining relevant studies published between 2015 and 2025 and retrieved from Google Scholar and PubMed. The selection process applied predetermined inclusion and exclusion criteria related to chronic disease populations, psychological factors, disease progression, and quality of life outcomes. Fourteen selected articles were analyzed and synthesized narratively. The findings showed that negative psychological factors, particularly stress and depression, were significantly associated with poor glycemic control, increased blood pressure, cardiovascular risk, exacerbation of chronic obstructive pulmonary disease, inflammation-related health problems, and reduced survival among patients with cancer. Anxiety and psychological distress were also related to poorer disease management and lower health-related quality of life. Conversely, protective psychological factors such as optimism and positive expectations were associated with better coping, reduced disability, improved functioning, and longer life expectancy. These findings indicate that psychological factors are important modulators of chronic disease progression through biological, behavioral, and psychosocial mechanisms. This review highlights the need to integrate mental health screening, counseling, psychoeducation, and psychosocial support into chronic disease management. Such integration may help patients regulate stress, strengthen adaptive coping, improve treatment adherence, and enhance overall quality of life.
Co-Authors Adhwa'a Kaylla Advaita, Chalisya Vanya Affandhy , Adhwa’a Kaylla Affandhy, Adhwa’a Kaylla Afirsta Rahma Nur Pratiwi Ahsanal Kasasiah Asep Bayu Dani Nandiyanto Aulia Fashanah Hadining Aulia Hadining Balapadang, Rachel Noveriachristie Bismar Al Bara Chalisya Vanya Advaita Daffa, Muhammad Naufal Dede Riyanto Dzannuba, Fadya Laila Esti Syahrin Fadilah, Oca Nur Firli Reisya Subekti Fitri Oktaviani Nurdin Fitri Otaviani Nurdin Gina Lova Sari Gun Gun Gumilar Hadining, Aulia Herlaesa, Shofiatulfuadah Retnaningrum Hermawan, Deri Hilm, Inda Laily Hilmi , Indah Laily Hotimah, Alin Parliana Ilham, Febrian Dzikri Indah Laily Hilmi Indah Laily Hilmi Izzati, Maulia Jahra Almas Shadrina Jasmine Rahma Saputri Keysha Feiruzyan Rafeifadattis Kusnadi Kusnadi, Kusnadi Lely Sulfiani Saula Linda Riski Sefrina Mally G Sholih Mally G. Sholih Mally Ghinan Mally Ghinan Mally Ghinan Sholih Mayasari Mayasari Mierza, Vriezka Muhammad Raka Tresna Muhammad Rizki Al Gibran Muini, Chantiara FM Mukarromah Dita Putri Munir Alinu Mulki Nabila Yokki Ani Eka Putri Nadhira, Shafwa Faza Nandita Nuryanti Aulia Nazwa Rizkillah Nisa, Nasywa Khoirun Noviani Ayu Mulyati Nurdin, Fitri Oktaviani Nurhafidah, Zahra Paulina Intan Deanita Puteri Rahma Maharani Rachel Noveriachristie Balapadang Rahma Maulida, Rahma Roudotul Jannah Sabina Khairunnisa Siagian Salman Salman Shadrina , Jahra Almas Shadrina, Jahra Almas Sholih, Mally Ghinan Sri Anggraeni Sri Ayu Ainurrosyidah Syahrin, Esti Triana Maudy Yulianti Surasa Verka Apriani Vriezka Mierza Wardani, Aulia Yulianti Surasa, Triana Maudy Zahra Nurhafidah