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Pengaruh Terapi Antituberkulosis Terhadap Pertumbuhan Penderita Tuberkulosis Anak di Kota Jambi Rahman, Ave Olivia; Ayu, Esa Indah; ., Miftahurrahmah
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 2 No. 2 (2014): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (306.792 KB) | DOI: 10.22437/jmj.v2i2.2711

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ABSTRACT Background: Tuberculosis (TB) is still a major health problem in the world. Indonesia is in the top fifth contributing to the highest number of TB cases in the world. Subdit TB Depkes RI 2000-2010 reported that Jambi is one of the province with high proportion of pediatric TB, 5,2%. Tuberculosis can affect the children’s growth. Combination of antituberculosis drugs are used in the  therapy of tuberculosis. Some studies show that the antituberculosis drugs cause side effects. Methods: This is an observational research with cohort prospective design. Subjects are patients  who diagnosed as pediatric TB in RSUD Raden Mattaher, Puskesmas Putri Ayu, Puskesmas Simpang IV Sipin and PPTI Jambi. Subjects have given informed consent. The recruitment of subject from July until September 2014 and followed until two month therapy. The primary data from interview and weight measurement, secondary data from patients’ medical records. Results: Total subjects are 24 patients. The 87,5% subjects diagnosed as TB pulmonary and 12,5% subjects diagnosed as TB extrapulmonary (meningitis TB, spondylitis TB and scrofuloderma). About 54,2% subjects are above 4 years old. The location of patients’ adresses are 20,8% from Kecamatan Jambi Timur subdistrict, followed respectively from Telanai, Kota baru, Pelayangan, Jelutung and  Danau Teluk. The 79,2 % subjects have close contact with positive TB adult patients. About 8,3% subjects experience loss of appetite, 4,1 % experience naussea during therapy with antitubercular drugs. Based on weight/age criteria, about 91,7 % subjects are categorized malnutrition and 8,3 % are well nutrition before therapy. There are different significantly increasement of body weight before, after 1 month and 2 month of therapy (p<0,05). Conclusion: There are significantly increasement of body weight before, after 1 month and 2 month of therapy (p<0,05).   Keywords: Pediatric TB, growth weight, side effects
FAKTOR-FAKTOR YANG MEMPENGARUHI NILAI PEAK FLOW METER PADA USIA PRODUKTIF DI KELURAHAN MAYANG MANGURAI KOTA JAMBI Ayudia, Esa Indah; Miftahurahmah; Harahap, Huntari
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 9 No. 1 (2021): Special Issues: JAMHESIC 2020
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (102.224 KB) | DOI: 10.22437/jmj.v9i0001.12901

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ABSTRACTAsthma is a common long-term inflammatory disease of the airways of the lungs. Asthma is characterized byvariable and recurring symptoms, reversible airflow obstruction, and easily induced bronchospasm. Symptomsinclude episodes of wheezing, coughing, chest tightness and shortness of breath. Asthma may occur severaltimes a day or several times per week. Asthma symptoms can get worse at night or with exercise, but this variesfrom person to person. The Peak Flow Meter is a simple, easy-to-use tool that measures peak expiratory flow(PEF) and detects airflow limitations. The peak flow meter is the recommended alternative for the diagnosis ofasthma. This study was an observational analytic study with a cross sectional design. The number ofrespondents was 32 people, measured the peak expiratory flow using a peak flow meter. The results of this studyindicate that gender, age, comorbidities and smoking history are factors that affect the value of the peak flowmeter.Keyword : Peak Flow Meter, lung, asthmaABSTRAKAsma adalah penyakit inflamasi jangka panjang yang umum terjadi pada saluran udara paru-paru.Asma ditandai dengan gejala yang bervariasi dan berulang, obstruksi aliran udara reversibel, danbronkospasme yang mudah diinduksi. Gejala termasuk episode mengi, batuk, dada sesak, dan sesaknapas. Asma dapat terjadi beberapa kali sehari atau beberapa kali dalam seminggu. Gejala asmabisa menjadi lebih buruk pada malam hari atau saat berolahraga, tetapi ini bervariasi dari orang keorang. Peak Flow Meter adalah alat sederhana dan mudah digunakan yang mengukur aliran ekspirasipuncak (PEF) dan mendeteksi batasan aliran udara. Pengukur aliran puncak adalah alternatif yangdirekomendasikan untuk diagnosis asma. Penelitian ini merupakan penelitian analitik observasionaldengan desain cross sectional. Responden berjumlah 32 orang, diukur aliran ekspirasi puncakmenggunakan peak flow meter. Hasil penelitian ini menunjukkan bahwa jenis kelamin, usia, penyakitpenyerta dan riwayat meroko merupakan faktor yang mempengaruhi nilai peak flow meter.Kata kunci : Peak Flow Meter, paru-paru, asma
PENGARUH PEMBERIAN JUS BUAH TERONG PIRUS (Cyphomandra betacea cav Sendtn) TERHADAP KADAR HDL TIKUS PUTIH (Rattus norvegicus) GALUR Wistar YANG DIINDUKSI DIET TINGGI LEMAK Albashir Feriohadi; Esa Indah Ayudia; Nyimas Natasha Ayu Shafira
Journal of Medical Studies Vol. 2 No. 1 (2022): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v2i1.18089

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ABSTRACT Tamarillo or tomato tree is rich in antioxidants that are useful for increasing blood HDL levels. This study aimed to determine the effect of tamarillo juice on blood HDL levels in white rats induced by a high-fat diet. The research design was True Experimental Pretest-Posttest Control Group Design. The research subjects were 28 male white rats of the Wistar strain which were divided into four groups. This study used tamarillo juice at doses of 75 mg/ml, 150 mg/ml, and 250 mg/ml. Blood HDL levels were checked on the 7th day, 21st day, and 47th day with a photometer. Data on blood HDL levels were analyzed by paired T-test and One-way Anova test. The results of the Paired T-test showed that there was a significant increase in HDL for all treatment groups after being given a high-fat diet. Meanwhile, after administration of tamarillo there was a significant decreased at dose of 250 mg/ml and no significant difference at dose of 75 mg/ml and dose of 150 mg/ml. The results of the One-way anova test showed that there was no significant difference between the study groups after administration of tamarillo. There was no effect of giving tamarillo at doses of 75 mg/ml and 150 mg/ml but there was a significant effect of decreasing HDL at a dose of 250 mg/ml on white rats Wistar strain induced by a high-fat diet. Keywords: Dyslipidemia, tamarillo, blood HDL levels, white Rat (Rattus norvegicus). ABSTRAK Terong pirus atau Terong belanda kaya akan antioksidan yang bermanfaat untuk menaikkan kadar HDL darah. Penelitian ini bertujuan untuk mengetahui pengaruh jus buah terong pirus terhadap kadar HDL darah pada Tikus Putih yang diinduksi diet tinggi lemak. Desain penelitian adalah True Experimental Pretest-Posttest Control Group Design. Subjek penelitian adalah 28 ekor Tikus Putih jantan galur Wistar yang terbagi dalam empat kelompok. Penelitian ini menggunakan dosis jus terong pirus 75 mg/ml, 150 mg/ml, dan 250 mg/ml. Kadar HDL darah diperiksa pada hari ke-7, hari ke-21, dan hari ke-47 dengan alat fotometer. Data kadar HDL darah dianalisis dengan Uji paired T-test dan Uji One-way Anova. Hasil Uji Paired T- test menunjukkan bahwa terjadi peningkatan yang signifikan HDL pada semua kelompok perlakuan setelah pemberian diet tinggi lemak. Setelah pemberian terung pirus terdapat penurunan yang signifikan pada dosis 250 mg/ml dan tidak terdapat perbedaan yang signifikan pada dosis 75 mg/ml dan dosis 150 mg/ml. Hasil Uji One-way annova didapatkan tidak terdapat perbedaan signifikan antar kelompok penelitian setelah pemberian terong pirus. Tidak terdapat pengaruh pemberian terong pirus pada dosis 75 mg/ml dan 150 mg/ml namun terdapat pengaruh penurunan HDL yang signifikan pada dosis 250 mg/ml terhadap tikus putih (Ratus norvegicus) galur Wistar yang diinduksi diet tinggi lemak Kata Kunci : Dislipidemia, terong pirus, kadar HDL darah, tikus Putih (Rattus norvegicus).
Pengaruh Diet Puasa Intermiten terhadap Kadar Trigliserida pada Tikus Putih Sprague Dawley Esa Indah Ayudia; Andini Agustina; Huntari Harahap; Miftahurrahmah; Irfanuddin
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 8 No. 2 (2021): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universi
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v8i2.172

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Trigliserida merupakan komponen lipid utama yang disimpan di jaringan adiposa berguna untuk sumber energi. Peningkatan kadar trigliserida dapat menyebabkan penyakit kardiovaskular. Salah satu cara untuk menurunkan kadar trigliserida yaitu dengan diet. Diet puasa intermiten adalah salah satu diet yang dapat dilakukan, dimana diet ini adalah diet dengan pembatasan waktu dan kalori. Diet puasa intermiten dibagi menjadi 3 metode yaitu Time restricted feeding, Alternate-day fasting dan Modified fasting. Penelitian ini dilakukan untuk melihat pengaruh diet puasa intermiten terhadap kadar trigliserida. Penelitian ini adalah penelitian eksperimental dengan menggunakan hewan coba tikus putih galur Sprague Dawley. Tikus putih akan dibagi menjadi 3 kelompok diet puasa intermiten dan 1 kelompok kontrol dan diberi diet sesuai kelompoknya selama 1 bulan. Penimbangan berat badan dan pengambilan darah dilakukan diawal dan akhir penelitian, kemudian hasil intervensi diet puasa intermiten dibandingkan dengan kelompok kontrol. Terdapat penurunan yang signifikan terhadap berat badan dengan nilai p 0,000 dan penurunan kadar trigliserida yang signifikan dengan nilai p 0,035 (p<0,05).
HUBUNGAN ANTARA ASUPAN MAKAN, STATUS GIZI DAN AKTIVITAS FISIK DENGAN KEJADIAN COVID-19 PADA ORANG DEWASA OVERWEIGHT DAN OBESITAS Raihanah Suzan; Rita Halim; Esa Indah Ayudia
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 10 No. 3 (2022): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (205.36 KB)

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ABSTRACT Background: Overweight and obesity has been known as a risk factor to get covid-19 and complication or severe covid-19. Due to government regulation like quarantine, people more susceptible to increased their weight in the pandemic covid-19 time. As It make people had difficulty to exercise outside their house and could increase dietary intake of unhealthy food. Aims and objective: our study aimed to investigate the association of dietary intake, nutritional status and physical activity with covid-19 in the overweight and obesity adult population. Method: we conducted a cross sectional study among adult with overweight and obesity in Jambi City. Dietary intake, nutritional status, physical activity and covid 19 data were collected using a FFQ semiquantitatif, GPAQ and structured questionaire respectively. The survey conducted from September to Oktober 2021. Results: A total 156 respondents have been included in the study, Most of the subjects age was between 18 -25 years (69,2%), and females (55,8%). Obesity was observed in 82,1% of the subjects with 78,2% subjects ate more than the recommendation, only 30,1% subjects had inactivity and 19,2% subjects had covid-19. There were 20 subjects (80%) who had covid-19 with over intake and obesity but it was not significant statistically. The physical activity also not related significantly to covid-19. Conclusions: In this study we found no significant association between the dietary intake, nutritional status, and physical activity with covid-19, however our data need to be confirmed and investigate in the future with more extensive population studies. Keyword: Covid-19, Dietary intake, Obesity, Physical activity ABSTRAK Latar belakang: Kelebihan berat badan dan obesitas diketahui meningkatkan risiko terkena Covid-19 dan komplikasi dari penyakit covid-19, atau Covid-19 yang parah. Peraturan pemerintah seperti karantina, mengakibatkan masyarakat lebih mudah untuk meningkatkan berat badannya selama masa pandemi Covid-19. Karena peraturan tersebut menyebabkan masyarakat kesulitan berolahraga di luar rumah dan dapat meningkatkan konsumsi makanan yang tidak sehat. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara asupan makan, status gizi, dan aktivitas fisik dengan kejadian Covid-19 pada orang dewasa overweight dan obesitas. Metode: Penelitian ini merupakan penelitian potong lintang pada orang dewasa overweight and obesitas di Kota Jambi. Data asupan makan, status gizi, aktivitas fisik, dan kejadian Covid-19 dikumpulkan menggunakan FFQ semikuantitatif, GPAQ, dan kuesioner terstruktur. Pengambilan data berlangsung dari bulan September hingga Oktober 2021. Hasil: Total responden yang mengikuti penelitian ini sebanyak 156 orang, sebagian besar responden penelitian berusia 18-25 tahun (69,2%) dan berjenis kelamin perempuan (55,8%). Obesitas di temukan pada 82,1% responden dengan 78,2% responden asupan makannya lebih, responden yang kurang aktif hanya 30,1% dan 19,2% responden pernah terkena penyakit covid-19. Terdapat 20 responden (80%) yang terkena covid-19 dengan asupan makan lebih dan obesitas tetapi hasil ini tidak signifikan secara statistik. Aktivitas fisik juga tidak berhubungan signifikan dengan covid-19. Kesimpulan: Tidak ditemukan hubungan yang bermakna secara statistik antara asupan makan, status gizi, dan aktivitas fisik dengan kejadian Covid-19 pada orang dewasa overweight dan obesitas (nilai P > 0,05). Kata kunci: Asupan makan, aktivitas fisik, covid-19, obesitas
IDENTIFIKASI VARIABLE DETERMINAN DEFISIENSI DAN INSUFISIENSI KADAR PLASMA VITAMIN D PADA WANITA USIA SUBUR Anggelia Puspasari; Herlambang Herlambang; Nyimas Natasha Ayu Shafira; Amelia Dwi Fitri; Rita Halim; Dhea Assyifa; Esa Indah Ayudia; Erny Kusdiyah; Citra Maharani; Rina Nofri Enis
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 10 No. 4 (2022): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.19 KB) | DOI: 10.22437/jmj.v10i4.20867

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Introduction: Vitamin D have played role as nutrition for reproductive age healthy. Indonesia is tropicalcountry which got sunshine along the year but previous study reported high prevalence of deficiency and insufficiency of Vitamin D. Factor which influence Vitamin D level is complex and may specific for the population.Objective: This study aimed to determined Vitamin D plasma level and factors influenced in it.Methods: This cross-sectional study attended by 23 non pregnant women in reproductive age between 20-45 years old. Plasma level of Vitamin D measure with CLIA. Risk factor assessed with questionnaire.Results: This study reported all the women have deficient and insufficient. Factor which statisticallysignificant associated with higher Vitamin D plasma level were older age, higher sun exposure score, history for delivery the baby, not applied sunscreen and Vitamin D supplement intake.Conclusion: There are several factors influence plasma vitamin D level in women at reproductive age other than sun exposure.Key words: sun exposure, Vitamin D, women in reproductive age
UPAYA PENINGKATAN POTENSI DIRI CREATIVE DOCTORPRENEUR DI ERA COMPETITIVE HEALTHPRENEUR BERBASIS DIGITAL MELALUI EDUKASI DAN INOVASI PLATFORM DESIGN HEALTHPRENEURSHIP Tia Wida Ekaputri Hz; Miftahurrahmah Miftahurrahmah; Esa Indah Ayudia; Raihanah Suzan; Willi Hardy Marpaung
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 6 No. 2 (2023): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/medicaldedication.v6i2.28988

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ABSTRACT In the current era of digitalization, healthpreneur products at affordable prices and good quality in the community have competitive value. Innovation in the health sector, especially to improve healthcare services, goes hand in hand with technological advances. The existence of competitive healthpreneurs motivates healthcare services to be universal and easier to access by the wider community. This community service activity aims to increase the potential of creative doctorpreneurs in the digital-based competitive healthpreneur era through education and innovative healthpreneurship design platforms. The activity was a webinar inviting resource persons in the digital-based doctorpreneur field and founders of several healthpreneurship platforms. Pretest, posttest and evaluation questionnaires were given to webinar participants. After the expert presentation, participants were allowed to discuss. Data analysis used the Wilcoxon test to determine the increase in knowledge participants. The number of webinar participants who participated was 290 students from 4 classes, namely 66 students from the Class of 2020, 99 students from the Class of 2021, 66 students from the Class of 2022 and 59 students from the Class of 2023. There was a significant difference in the pretest and posttest scores of the webinar participants. (P-value=0.008). The activity evaluation results through the webinar satisfaction questionnaire showed that most participants stated that the seminar activities were very good and good. This webinar activity is proven to increase knowledge about the potential of creative doctorpreneurs in the digital-based competitive healthpreneur era. Keywords: creative doctorpreneur, competitive healthpreneur, platform design healthpreneurship   ABSTRAK Di era digitalisasi saat ini, produk healthpreneur dengan harga terjangkau dan berkualitas di komunitas masyarakat telah memiliki nilai kompetisi. Inovasi di bidang kesehatan khususnya dalam upaya meningkatkan healthcare service bergandengan dengan kemajuan teknologi. Dengan adanya competitive healthpreneur memotivasi healthcare service bersifat universal dan lebih mudah untuk diakses oleh masyarakat luas. Tujuan dari pelaksanaan kegiatan pengabdian kepada masyarakat ini adalah untuk meningkatkan potensi diri creative doctorpreneur di era competitive healthpreneur berbasis digital melalui edukasi dan inovasi platform design healthpreneurship. Kegiatan dilangsungkan secara webinar dengan mengundang narasumber di bidang doctorpreneur berbasis digital dan founder beberapa platform healthpreneurship. Pretest dan posttest serta kuesioner evaluasi kegiatan diberikan kepada peserta webinar. Setelah dilakukan pemaparan oleh narasumber, diberikan kesempatan untuk diskusi kepada peserta. Analisa data digunakan uji Wilcoxon untuk mengetahui peningkatan pengetahuan. Jumlah peserta webinar yang berpartisipasi sebanyak 290 mahasiswa yang berasal dari 4 angkatan, yaitu 66 orang Angkatan 2020, 99 orang Angkatan 2021, 66 orang Angkatan 2022 dan 59 orang Angkatan 2023.. Terdapat perbedaan yang signifikan nilai pre-test dan post-test peserta webinar (P-value=0,008). Hasil evaluasi kegiatan melalui kuesioner kepuasan webinar menunjukkan mayoritas peserta menyatakan kegiatan seminar sangat baik dan baik. Kegiatan webinar ini terbukti dapat meningkatkan pengetahuan tentang potensi diri creative doctorpreneur di era competitive healthpreneur berbasis digital. Kata kunci: creative doctorpreneur, competitive healthpreneur, platform design healthpreneurship
Studi Literatur : Luaran Fungsional Pasien Hirshcsprung Pasca Pull-Through Berdasarkan Skor Rintala Muhammad Arvienji Wardaya; Miftahurrahmah Miftahurrahmah; Esa Indah Ayudia; Willy Hardy Marpaung; Humaryanto Humaryanto; Budi Justitia
Jurnal Litbang Edusaintech Vol. 3 No. 2 (2022): Volume 3 No 2 2022
Publisher : Litbang PWM Jawa Tengah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51402/jle.v3i2.23

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Hirschsprung's disease is a disorder that causes interference with the absence of innervation in the colon, causing peristalsis in the colon. Treatment of Hirschsprung performed surgically using the Pull-through method. Data regarding the post-pull-through functional outcome has not been obtained, especially in Indonesia. Using the Rintala score, this study aims to analyze the functional outcome of post-pull-through Hirschsprung patients based on the Rintala score from a literature study. This study used a literature review approach as many as fifteen literature sources from Google Scholar, Pubmed, Science Direct, Elsevier and DOAJ according to the inclusion criteria set by the researcher. Based on the results of the literature study, from 15 literatures there are 14 literature have information about the age, sex, and complications of Hirshscprung patients after the pull-through. And from 15 literatures, all literature has information about post Pull-though evaluation using the Rintala score and the type of Pull-through operation used. Based on the gender of the Hirschsprung patient, it was more common in boys, the age at evaluation ranged from 3 to 11 years. Post pull-through complications are enterocolitis, anastomotic stricture, and constipation. The results of the Rintala scoring show that the interpretation of "continence is good" in all the literature and most of the literature uses the TEPT technique. Keyword:Hirschsprung Disease, Pull-through, Rintala Score ABSTRAK Penyakit Hirschsprung merupakan kelainan yang ditandai dengan tidak adanya persarafan pada kolon sehingga menyebabkan gangguan peristaltik pada kolon. Penanganan Hirschsprung dilakukan pembedahan dengan metode Pull-through. Data mengenai hasil luaran fungsional pasca pull-through belum banyak didapatkan terutama di Indonesia Dengan menggunakan skor Rintala, penelitian ini bertujuan untuk menganalisis luaran fungsional pasien Hirschsprung pasca Pull-through berdasarkan skor Rintala dari studi literatur. Penelitian ini menggunakan pendekatan studi literatur sebanyak lima belas sumber literatur yang diperoleh dari mesin pencari Google Scholar, Pubmed, Science Direct, Elsevier dan DOAJ sesuai dengan kriteria inklusi yang telah ditetapkan peneliti. Berdasarkan hasil studi literatur, dari 15 literatur terdapat 14 literatur yang memiliki informasi mengenai usia, jenis kelamin, dan komplikasi pasien Hirshscprung pasca pull-through. Kemudian, dari 15 literatur, semua literatur memiliki informasi mengenai evaluasi pasca Pull-though menggunakan skor Rintala serta jenis operasi Pull-through yang digunakan. Berdasarkan jenis kelamin pasien Hirschsprung lebih banyak terjadi pada anak laki, usia saat evaluasi berkisar 3-11 tahun. Komplikasi pasca Pull-through ditemukan berupa enterokolitis, striktura anastomosis, dan Konstipasi. Skoring rintala didapatkan hasil interpretasi “kontinensia Baik” di semua literatur dan sebagian besar literatur menggunakan teknik TEPT Kata kunci: Hirschsprung, Pull-through, Skor Rintala
Effects of Sub-acute Ethanol Extract Toxicity of Karamunting (Rhodomyrtus tomentosa) Leaves on Hematological Profile in Female White Rats Tia Wida Ekaputri; Hana Nurul Qur’ani; Citra Maharani; Anggelia Puspasari; Budi Justitia; Esa Indah Ayudia; Fitriyanti
Journal of Medical Studies Vol. 4 No. 3 (2024): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v4i3.38943

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ABSTRACT Background: Karamunting leaves (Rhodomyrtus tomentosa) are a medicinal plant widely used in Indonesia for their bioactive compounds, which exhibit anti-inflammatory, antibacterial, antioxidant, antidyslipidemic, and anti-hyperglycemic properties. However, the safe dosage for human use remains undetermined. This study aims to assess the sub-acute toxicity of ethanol extracts of karamunting leaves on the hematological profile of female white rats. Methods: This study used an experimental laboratory design with a post-test control group. Karamunting leaves were extracted by maceration using 70% ethanol as the solvent. The hematological profiles measured included erythrocytes, leukocytes, platelets, and hematocrit levels. Female white rats of the Wistar were randomly divided into six groups. The negative control group received only a 0.5% Na CMC suspension, while the treatment groups received ethanol extracts of karamunting leaves at doses of 200 mg/kg BW, 400 mg/kg BW, 800 mg/kg BW, 1600 mg/kg BW, and 3200 mg/kg BW. Blood samples were collected after 14 days of treatment. Results: The hematological profiles indicated no significant differences among the groups. However, the treatment group that received extracts at a dose of 1600 mg/kg BW showed a poor hematological profile. Conclusion: Generally, the ethanol extract of karamunting leaves did not affect the hematological profiles of the test animals. Keywords: Rhodomyrtus tomentosa; hematological profile; sub-acute toxicity
Relationship between Knowledge Level and Community Attitude in Dengue Fever Prevention Behavior Arief Romadhan; Putri Sari Wulandari; Rina Nofri Enis; Wahyu Indah Dewi Aurora; Esa Indah Ayudia
Journal of Medical Studies Vol. 4 No. 3 (2024): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

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Abstract

ABSTRACT Background: Dengue Hemorrhagic Fever (DHF) is an acute infectious disease caused by the Dengue virus which is transmitted by the Aedes aegypti mosquito. In cases of dengue fever, the symptoms often experienced by sufferers are sudden high fever, frequent bleeding, and if it is severe, they will experience shock and death. This research aims to determine the relationship between the level of knowledge and attitudes of the community in the behavior of preventing Dengue Fever in Jambi city in 2023. Methods: This research design used quantitative research with a cross-sectional design. The sample for this study comprised of residents from Kenali Besar, Paal V, and Payo Silincah Health Centers, totaling 86 respondents. Research instruments utilized questionnaires. The data were analyzed univariately and bivariately with the chi-square test. Results: Among the respondents, 41 individuals (47.7%) exhibited a good level of knowledge, 52 individuals (60.5%) demonstrated a positive attitude, and 37 individuals (43%) displayed good behavior. From the chi-square test, a p-value of 0.000 was obtained between the level of knowledge and preventive behavior towards dengue fever. A p-value of 0.000 was also obtained between attitudes and preventive behavior towards dengue fever. Conclusion: The level of knowledge and attitude of the community has a relationship with dengue prevention behavior in Jambi city. Keywords: dengue hemorrhagic fever (DHF); dengue fever; behavior; knowledge; attitude
Co-Authors Ade Tan Reza Ahmad Syauqy Albashir Feriohadi Amalia, Fenny Amatullah, Afifah Amelia Dwi Fitri Amelia Dwi Fitri, Amelia Dwi Anati Purwakhanti Andini Agustina Andini Agustina Anggelia Puspasari Anggraini, Bayu Anton Trihartanto Arief Romadhan Armaidi Darmawan Asty, Zahra Frizki Ave Olivia Rahman Budi Justitia Budi Justitia Calista, Amanda Athiyyah Citra Maharani Denok Tri Hardiningsih dewi, hasna Dhea Assyifa Ekaputri, Tia Wida Erny Kusdiyah Fairuz Quzwain Fairuz, Fairuz Fitriyanti Gading, Patrick Wiliam Hafizah Hafizah Hafizah Hafizah Hafizah Haifa Nida Firdausa Hana Nurul Qur’ani Hanina, Hanina Harahap, Asro Hayani Herlambang HERLAMBANG HERLAMBANG Humaryanto Humaryanto Huntari Harahap Husnun Nisa Iksan, Pahrul Imam Taufiq Siregar, Mara Indri Okta Sapitri Irfannuddin Irfannuddin Irfanuddin Iskandar, Mirna Marhami Justitia, Budi Keisya Dzikrina Putri La Ode Reskiaddin Lestari, Nur Afni Lipinwati ., Lipinwati Maulidia Imastary Tan Miftahurahmah Miftahurrahma, Miftahurrahma Miftahurrahmah Miftahurrahmah, Miftahurrahmah Muhammad Anharuddin Muhammad Arvienji Wardaya Munadi Munadi Mutiarahma Nindia Aryanti Nur Afni Lestari Nuriyah Nuriyah Nuriyah, Nuriyah Nyimas Natasha Ayu Shafira Octaviani, Jelica Okta Arizki Patrick Wiliam Gading Putra Agung, Rhonaz Putri Sari Wulandari Raihanah Suzan Rayandra Asyhar Rina Nofri Enis Rita Halim Rita Halim Samsirun Halim Subhan, Rahmatika Susan, Raihanah Suzan, Raihanah Tengku Arief Buana Perkasa Tia Wida Ekaputri Veonika, Dea Anenta Wahyu Indah Dewi Aurora Wida Ekaputri Hz, Tia Wida, Tia Willi Hardy Marpaung Willy Hardy Marpaung Willy Hardy Marpaung Willy Hardy Marpaung Zahra Frizki Asty Zilzikridini Wijayanti