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Journal : The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy

Endoscopic Features of Patients with Bronchial Asthma and Gastroesophageal Reflux Symptoms Syafruddin AR Lelosutan; Agus Dwi Susanto; Ruswhandi M
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 7, ISSUE 3, December 2006
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/73200667-71

Abstract

Background: Studies evaluating endoscopic results in patients with bronchial asthma and Gastroesophageal Reflux Disease (GERD) in Gatot Soebroto hospital have never been undertaken. It leads an idea to further study, in order to find a more accurate and rapid management as solution for anticipating asthma attack and complications of bronchial asthma to upper gastrointestinal tract. Methods: A retrospective study was aimed to evaluate endoscopic result of upper gastrointestinal tract in bronchial asthma patients who had GERD symptoms as appropriate to the criteria of 4 major GERD symptoms of Talley 2002. Data was collected in one year period starting from November 2004 to October 2005. Results: Subject characteristics in this study indicated that there were more female patients compared to male with a ratio approaching 3:1 who had such symptoms. Mean age was 38.5 years and ratio of body weight to body height indicated normal weight result and the mean value for duration of asthma was 27 years. Clinical symptoms of GERD found in the present study was in accordance with four majors symptoms of GERD i.e. 32 (100.00%) cases of regurgitation, 29 (90.63%) cases for each of heartburn and non-cardiac chest pain symptom, and 7 (21.88%) cases of difficult / painful swallowing or dys/odinophagia. The endoscopic result of upper gastrointestinal tract had figured of: (1) 4 (12.50%) cases of normal esophagus, (2) 11 (34.40%) cases of non-erosive esophagitis known as Non Erosive Reflux Disease (NERD), and (3) erosive esophagitis which regarding to Los Angeles classification: 15 (46.90%) cases of grade A and 2 (6.20%) cases of grade B. Conclusion: The incidence of esophagitis in accordance with LA classification is extremely high although no severe damage (grade C and grade D) was found. Early anticipation of reflux associated respiratory symptoms and anti-reflux treatment should be considered in order to shorten or to discontinue the asthma attack cycle. Keywords: bronchial asthma, GERD, endoscopy, NERD
Co-Authors Achmad Hudoyo Adityo Wibowo Agustin, Heidy Ahmad Hudoyo Airin Aldiani Alfiyyah, Arifah Amien, Bagus Radityo Anna Rozaliyani Anna Yusrika Antono, Wahyu Arief Riadi Arifin Arif Widiyantoro Arifin Nawas Arifin Nawas Arifin, Arief Riadi Ary Indriana Savitri Ayesya Nasta Lestari Ayuningtyas, Putu Duhita Bahtiar Husain Bambang Dwi Hasto Baskoro, Hario Budhi Antariksa Budi Prasetyo Budi Prasetyo Caecilia Marliana Caecilia Marliana Deva Bachtiar Dewi Yennita Sari Diah Handayani Dita Kurnia Sanie Dita Kurnia Sanie Dita Kurnia Sanie Djasri , Hanevi Erlina Burhan Fahrial Harahap Fahrial Harahap Faisal Yunus Faisal Yunus Faiza Hatim Farhan Hilmi Taufikulhakim Feni Fitriani Feni Fitriani Fiona Lestari, Fiona Fransisca Sinaga Galoeh Adyasiwi Ginting, Tribowo Tuahta Habibi, Januar Hario Baskoro Harris Abdullah Haruyuki Dewi Faisal Hasibuan, Thariq Emyl Taufik Hasto, Bambang Dwi Hayati, Mulida Hera Afidjati Herman Suryatama Hetti Rusmini Husain, Bahtiar Ibrahim Nur Insan Putra Darmawan INDRA YOVI Indy Larasati Wardhana Isbaniah, Fathiyah Isti Mardiana Soetartio Kartikawati, Falah Khairunnisa Imaduddin Kristianto, Kiki Kurniawidjaja, Meily Lestari, Ayesya Nasta Lestari, Fetrina Malsephira Hasmeryasih Marini Puspita Sari Maylani, Lina Mega Juliana Menaldi Rasmin Mia Elhidsi Mirza Purwitasari Mohamad Fahmi Alatas Momon, Ade Muchtarrudin Mansyur Muhammad Alkaff Muhammad Ilyas Mukhtar Ikhsan Nalapraya , Widhy Yudistira Nesia Priandari Nina Aspiah Nina Ratu Nur Kharima Notariza, Kemas Rakhmat Nury Nusdwinuringtyas Nuryunita Nainggolan Prasenohadi Prasenohadi Putra, Andika Chandra Putri C Eyanoer Putri Suci Putri Suci Ramadhany Rahardjo, Tri Apriliawan Bendarto Ratnawati Ratnawati Retno A S Soemarwoto Retno Ariza S Soemarwoto Rita Rogayah Robiana Modjo Rudi Kurniawan Rudy Satriawan Ruswhandi M Samoedro, Erlang Satria Pratama Satria Pratama Savitri, Ary Indriana Seira Putri Boru Rambe Septauli, Kolanda Maria Sita Andarini Sita Laksmi Andarini Soehardiman, Dicky Sri Wening Pamungkasningsih Syafruddin AR Lelosutan Syazili Mustofa Tarigan, Amira Permatasari Taufik, Feni Fitriani Tugas Ratmono Tugas Ratmono, Tugas Wahyuni, Hendra Widjanantie, Siti Chandra Wirya Sastra Amran Zaini, Jamal