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All Journal Journal of Food and Pharmaceutical Science Indonesian Journal of Cancer Chemoprevention Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY BELIA: Early Childhood Education Papers Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Phinisi Integration Review Syntax Literate: Jurnal Ilmiah Indonesia Biosaintifika: Journal of Biology & Biology Education ASEAN Journal of Community Engagement Jurnal E-Bis: Ekonomi Bisnis Reswara: Jurnal Pengabdian Kepada Masyarakat Proceedings Series on Social Sciences & Humanities Journal Didaskalia Pharmaceutical Sciences and Research (PSR) Jurnal Akuntansi dan Keuangan Indonesia Al Iqtishadiyah: Journal of Islamic Economics and Finance Jurnal Natural Cendikia: Jurnal Pendidikan dan Pengajaran Journal of Food and Pharmaceutical Sciences JIFA (Journal of Islamic Finance and Accounting)
Rumiyati, Rumiyati
Department Of Pharmaceutical Chemistry, Faculty Of Pharmacy, Universitas Gadjah Mada, Sekip, Utara Yogyakarta 55281, Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences Other

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PELATIHAN UMKM MELALUI STRATEGI PEMULIHAN EKONOMI TERDAMPAK COVID-19 DI DESA SINDUADI Oktyawati, Dianila; Rumiyati, Rumiyati; Siregar, Hilda Octavana; Fajri, Faridiah Aghadiati
Reswara: Jurnal Pengabdian Kepada Masyarakat Vol 4, No 2 (2023)
Publisher : Universitas Dharmawangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46576/rjpkm.v4i2.3306

Abstract

Pandemi Corona Virus Disease 2019 (Covid-19) telah mempengaruhi berbagai sektor. Salah satunya adalah sektor perekenomian, terutama bagi pelaku UMKM. Apalagi dengan pemerintah mengeluarkan kebijakan Pembatasan Sosial Berskala Besar (PSBB) guna mencegah penyebaran virus Corona membuat omset UMKM turun drastis. PSBB ini meliputi menghentikan sementara kegiatan belajar di sekolah  menjadi belajar di rumah (study from home) bagi para pelajar hingga anjuran agar bekerja dari rumah (work from home) bagi sejumlah kalangan pekerja, membatasi kegiatan keagamaan, dan membatasi kegiatan di tempat atau fasilitas umum (Keputusan Presiden No 11 Tahun 2020). Kondisi ini berdampak bagi UMKM karena sepi pembeli. Salah satu daerah yang terkena dampak ini adalah Desa Sinduadi dimana desa ini merupakan desa yang padat industri, dekat kampus, sekolah, dan daerah pariwisata. Tujuan pengabdian ini adalah untuk membantu memulihkan perekonomian UMKM yang terdampak Covid-19 di Desa Sinduadi Kecamatan Mlati Kabupaten Sleman. Metode yang digunakan adalah pelatihan strategi pemulihan ekonomi UMKM akibat terdampak Covid-19 dan pemberian bantuan modal kepada UMKM di Desa Sinduadi. Hasil kegiatan ini adalah pelaku UMKM mendapatkan stimulus bantuan modal dan memiliki strategi pemulihan ekonomi pada usahanya akibat terdampak Covid-19. Kesimpulan dari kegiatan ini adalah pelaksanaan kegiatan berjalan dengan lancar dan pelaku UMKM memiliki pengetahuan tentang strategi bertahan menghadapi Covid-19, seperti mampu mengenali perilaku baru masyarakat, mampu beradaptasi dengan cepat dan tanggap, mampu memanfaatkan teknologi dan internet untuk keberlangsungan usaha, dan mampu membaca dan menganalisis peluang produk dan jasa yang dibutuhkan di masa pandemi Covid-19, dan mengelola keuangan usahanya
Cytotoxic Activity and Senescence Modulatory Effect of Hesperetin on Triple-Negative Breast Cancer Cells and Kidney Cells Co-Treatment with Cisplatin Artanti, Anif Nur; Jenie, Riris Istighfari; Rumiyati, Rumiyati; Meiyanto, Edy
Indonesian Journal of Cancer Chemoprevention Vol 14, No 3 (2023)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev14iss3pp181-188

Abstract

Cisplatin (Cisp) is a non-specific chemotherapeutic agent for breast cancer. Hesperetin (HST), a flavanone found in various citrus fruits, exhibits bioactive properties, functioning as an antioxidant, anti-inflammatory, and anticancer agent. The objective of this research was to investigate the potential of HST as a co-chemotherapeutic agent in conjunction with Cisp, specifically focusing on its cytotoxic effects against 4T1 triple-negative breast cancer cells and senescence modulatory effect on Vero normal kidney cells. The cytotoxic effect and viability cell of HST were evaluated through 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) assay. In addition, the effect of cellular senescence inhibition on the Vero cell line was measured using senescence-associated β-galactosidase (SA-β-gal) staining. In the MTT assay, both HST and cisplatin demonstrated a reduction in the viability of 4T1 cells in a dose-dependent manner, yielding IC50 values of 498 μM and 2 μM, respectively. The co-treatment of HST and cisplatin showed an increase in sensitivity of the 4T1 cells with a combination index of <1. HST showed low cytotoxic activity against Vero cells, with IC50 values of over 500 μM. HST decreased cellular senescence induced by cisplatin exposure on Vero cells. These results indicated that HST in co-treatment with cisplatin decreased 4T1 cell viability synergistically. HST independently reduces the cellular senescence of normal cells. Consequently, HST holds promise for potential development as a co-treatment agent in combination with cisplatin for breast cancer cells, and it may also serve as an alternative for counteracting senescence in healthy tissues.Keywords: cytotoxic, senescence, hesperetin, cisplatin, breast cancer.
Empowering Women as Family Financial Planners: A Mitigation of the Pandemic's Economic Impact Fajri, Faridiah Aghadiati; Siregar, Hilda Octavana; Oktyawati, Dianila; Rumiyati, Rumiyati
ASEAN Journal of Community Engagement Vol. 7, No. 1
Publisher : UI Scholars Hub

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Abstract

This article discusses a community engagement program that supports housewives as financial managers in difficult times, like COVID-19 Pandemic. This paper believes in the capacity of housewives, particularly in managing the financial conditions of the domestic. The pandemic conditions affect the world in multiple aspects and levels. Physical distancing as one of the policies applied had a wide impact, especially in the economic sector, globally and locally. The temporary shutdown of various business sectors has impacted the society, starting with a decrease in the family’s income, continuing with the difficulties to meet their needs, and eventually their welfare. This article studies the implementation of a community project in Sinduadi Village, Yogyakarta, Indonesia, focusing on family financial planning (FFP), which arguably can assist housewives to manage their finances during challenging periods. Starting from compiling materials for the introduction of the FFP application, the program was conducted through a series of training and discussion activities, setting forum for obtaining assistance from financial management experts. After the training, several domestic financial problems can be identified by the housewives, which help them to outline their priorities and thus make a better financial plan for the future.
Comparative Physicochemical Characterization of Porcine, Fish, and Bovine Gelatin in Gummy Candies: Toward Halal Nutraceutical Development Laksitorini, Marlyn Dian; Darsih, Cici; Yuniarti, Nunung; Rumiyati, Rumiyati; Abidin, Mohammad Zainal
Pharmaceutical Sciences and Research Vol. 12, No. 3
Publisher : UI Scholars Hub

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Abstract

Gummy candies have emerged as one of the most popular dosage forms for multivitamins and nutraceutical supplements, including those for brain health. Gelatin is the primary gelling agent used to achieve the gummy texture; however, the influence of different gelatin sources on the physicochemical properties of gummies has not been systematically examined. This study investigated the physicochemical characteristics of gummies prepared with porcine, bovine, and fish gelatin. The gummies were evaluated for mechanical properties (gumminess, hardness, cohesiveness, springiness, adhesiveness, and stringiness), color, water activity, antioxidant activity, and protein content. Additionally, the effects of intentional adulteration—specifically the addition of porcine gelatin to fish or bovine gelatin—were assessed. The results showed that gumminess, hardness, cohesiveness, and springiness were comparable across different gelatin sources, whereas adhesiveness and stringiness were highly sensitive to source variation. Notably, adulteration with porcine gelatin significantly altered those two parameters. These findings underscored the importance of verifying gelatin origin in gummy formulations, as source-related variations and gelatin adulteration could have a direct impact on product quality and performance.
Co-Authors ., Sismindari A.A. Ketut Agung Cahyawan W Abdul Rohman Adjara, Syafia Mustika Aisyah, Andi Nur Anif Nur Artanti, Anif Nur Annisa, RR Rifka Arifin, Muhammad Fajar Arin Pranesti Ariwibowo, Daniel Binar, Sri Burhan, Asril Cici Darsih Dianila Oktyawati, Dianila Ediati Sasmito Edy Meiyanto Efi Miftah Faridli Endang Lukitaningsih Endang Purwati RN Endang Semiarti Enstini, Ni Luh Putu Yulina Evie Andriyani, Evie Fajri, Faridiah Aghadiati Frida Fanani Rohma Hofisah, Utbah Aminatul I.A., Ida Ayu Putu Indah Ika Puspita Sari Ika Puspitasari Irfan Muris Setiawan Juanda Juanda Khamidun, Khamidun Khamidun, Khamidun kusairi kusairi, kusairi Kusumanigrum, Aprilia Dyah Lilis Setyarini Mariyani MARLINI, WENNY Marlyn Dian Laksitorini, Marlyn Dian Meti Christiana Meti Indrowati Mohammad Zainal Abidin Nabella Duta Nusa Nawwaruddin, Hazza Hammam Ni Putu Linda Laksmiani Nunung Yuniarti Nursenta Dahliana Purba Purnomo, Kardianto Indra Rahim, Kurnia Rarastoeti Pratiwi Rasyid, Rusman Riris Istighfari Jenie Ritmaleni, Ritmaleni Rochmy Istikharah RR. Ella Evrita Hestiandari Sari, Miftiana Nugraha Setiaji, Arkan Siregar, Hilda Octavana Sismindari . Sony Warsono Sophian, Alfi Sri Rahayu W., Sri Rahayu Syamsu Nur, Syamsu Widayanti, Agnisa Widianto, Kasiatin Zulfitria Zulfitria, Zulfitria