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PROFIL UREUM DAN KREATININ SERUM SEBAGAI INDIKATOR DISFUNGSI GINJAL PADA PENDERITA HIV YANG MENDAPAT TERAPI ANTIRETROVIRAL Susanti, Susanti; Idris, Sri Aprilianti; Firdayanti, Firdayanti
Jurnal Ilmiah Kesehatan Ar-Rum Salatiga Vol 9, No 2 (2025)
Publisher : STIKES Ar-Rum Salatiga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36409/jika.v9i2.263

Abstract

Human Immunodeviciency Virus (HIV) merupakan Retrovirus golongan RNA yang menyerang kekebalan tubuh manusia. Penderita HIV harus memakai obat ARV seumur hidup yang untuk mencegah replikasi virus HIV di dalam tubuh. Efek samping dari penggunaan obat Antiretroviral terjadi toksisitas yang akan menyebabkan terganggunya fungsi ginjal yang ditandai oleh suatu kondisi yang memicu infeksi neoplasma sekunder, dan manifestasi neurologis dari kadar ureum. Penelitian ini dilaksanakan di Laboratorium Kimia Klinik Analis Kesehatan Politeknik Bina Husada Kendari pada bulan April 2019. Tujuan dari penelitian ini adalah untuk mengetahui profil ureum dan kreatinin serum sebagai indikator disfungsi ginjal pada penderita HIV yang mendapat terapi antiretroviral. Jenis Penelitian yang digunakan adalah deskriptif analitik dengan metode pengambilan sampel cross sectional study untuk melakukan pemeriksaan kadar ureum dan kreatinin pada 20 sampel darah penderita HIV/AIDS dengan menggunakan tekhnik pengambilan sampel total sampling serta dianalisis secara statistik menggunakan uji regresi linear sederhana. Hasil penelitian menunjukkan hasil analisis secara statistik menggunakan regresi linear sederhana menunjukkan bahwa nilai yang signifikan p=0,684 (p>0,05) artinya tidak terdapat hubungan antara lama penggunaan obat ART dengan kadar ureum dan kreatinin pada penderita HIV.
Pencegahan Kecacingan Melalui Pendampingan Pembiasaan Pola Hidup Bersih Sehat dan Pemeriksaan Kecacingan pada Anak-Anak Di SD Negeri 3 Konawe Selatan: Pencegahan Kecacingan Melalui Pendampingan Pembiasaan Pola Hidup Bersih Sehat dan Pemeriksaan Kecacingan pada Anak-Anak Di SD Negeri 3 Konawe Selatan Aulya, Muhammad Sultanul; Idris, Sri Aprilianti; Fusvita, Angriani; firdayanti, Firdayanti; Fusvita; Umar, Ani; Idris, Kemal; Wenty, Darmayanita
Jurnal Pengabdian Magister Pendidikan IPA Vol 6 No 4 (2023): Oktober-Desember 2023
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v6i4.6202

Abstract

Worm infections caused by Soil Transmitted Helminth (STH) are intestinal nematode worms which are transmitted through the soil in their life cycle. The various kinds of nematode class worms that are known are roundworms (Ascaris Lumbricoides), whipworms (Trichuris trichiura) and hookworms (Ancylostoma duodenale and Necator americanus). Worms have a very bad effect on health, in children worms will have an impact on learning disorders, decreased quality of intelligence and reduced nutritional intake. The aim of this community service activity is to provide socialization on the prevention of worms through assistance in getting used to a clean, healthy lifestyle and checking for worms among children at SD Negeri 3 Konawe selatan. The respondents in this activity were children at SD Negeri 3 Konawe selatan and 31 stool samples were obtained. The results of stool examination using the direct method on 31 children's stool samples did not find positive samples and 31 children's stool samples did not contain intestinal nematode worm eggs.
GAMBARAN UROBILINOGEN PADA MASYARAKAT YANG MENGONSUMSI KAMEKO DI KELURAHAN MANGGA DUA KOTA KENDARI Idris, Sri Aprilianti; Balaka, Kemal Idris; Santoso, Edwin
Jurnal Analis Kesehatan Kendari Vol. 5 No. 1 (2022): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 5 (1) Desember 2022)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v5i1.209

Abstract

Urobilinogen is a by-product formed by the reduction of bilirubin and is a colorless component produced by bacteria in bilirubin in the intestine. Determination of the amount of urobilinogen excreted in a given period allows to help in diagnosing liver dysfunction. Kameko is a drink containing ethanol made from fermented sap then mixed with mangrove wood. The consumption of kameko alcohol is at risk for impaired liver function, which is divided into fatty liver (fatty liver), alcoholic hepatitis (alcoholic hepatitis), and cirrhosis (cirrhosis). The purpose of this study was to determine the description of urobilinogen in people who consume kameko alcohol in Mangga Dua Village Kendari City. The method used in this study is an analitik descriptif, method with purposive sampling, which has the categories of male population, age 18-40 years, and duration of consuming kameko at least 2-10 years and sample examination is carried out using a Urine Analyzer ( Verify U120). The results showed that, from a total of 32 patients who underwent examination, 14 patients had urine urobilinogen levels of 0.2 mg/dL and 18 patients had urine urobilinogen levels of 1.0 mg/dL. Urine urobilinogen levels in 32 patients were normal, ie 0.2-1.0 mg/dL. Key Words : Urobilinogen, Kameko, Mangga Dua Village
GAMBARAN JUMLAH KOLONI BAKTERI PADA PENGGUNA GIGI TIRUAN (LEPAS PASANG) DI KOTA KENDARI Idris, Sri Aprilianti; Welliam, Desih; Ayunis, Citra
Jurnal Analis Kesehatan Kendari Vol. 6 No. 1 (2023): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 6 (1) Desember 2023)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v6i1.288

Abstract

ABSTRACT Penggunaan gigi tiruan yang lepas pasang dapat meningkatkan risiko pertumbuhan bakteri. Hal ini dikarenakan celah antara gigi tiruan dan gusi dapat menjadi tempat bagi bakteri untuk berkembang biak. Pengguna gigi tiruan disarankan untuk membersihkan dan merawat gigi tiruan mereka secara teratur dengan menyikat, membersihkan, dan merendam gigi tiruan dalam larutan pembersih yang direkomendasikan. Tujuan : Untuk mengetahui jumlah koloni bakteri pada pengguna gigi tiruan (lepas pasang) Di BTN Dewi Bunga Poasia 2 kota Kendari. Metode Penelitian kualitatif dapat dipahami sebagai metode penelitian eksperimental. Hasil : Hasil penelitian pada perlakuan pertama pada setiap sampel yang menggunakan gigi tiruan dilakukan isolasi sampel pada media NA di inkubasi 1 x 24 jam pada suhu 37℃, tahap kedua dilakukan perhitungan jumlah koloni bakteri dengan menggunakan alat CFU, dan tahap ketiga dilakukan pewarnaan gram pada sampel ditemukan hasil bakteri gram positif. Kesimpulan : Berdasarkan hasil penelitian yang telah dilakukan dapat disimpulkan bahwa : Pada pengenceran 10-6 sampel 1 terdapat 258 koloni bakteri, sampel 2 terdapat 93 koloni bakteri, sampel 3 terdapat 71 koloni bakteri, sampel 4 terdapat 25 koloni bakteri, sampel 5 terdapat 19 koloni bakteri, sampel 6 terdapat 905 koloni bakteri, sampel 7 terdapat 700 koloni bakteri, sampel 8 terdapat 511 koloni bakteri, sampel 9 terdapat 407 bakteri, sampe 10 terdapat 291 bakteri. Kata kunci: Jumlah koloni, bakteri, gigi tiruan ABSTRAK The use of removable dentures can increase the risk of bacterial growth. This is because the gap between the denture and the gums can be a place for bacteria to multiply. Denture wearers are advised to clean and care for their dentures regularly by brushing, cleaning, and soaking the dentures in the recommended cleaning solutions. Objective: To determine the number of bacterial colonies in denture users (removable) at BTN Dewi Bunga Poasia 2, Kendari city. Qualitative research methods can be understood as experimental research methods. Results: The results of the research in the first treatment for each sample using dentures were carried out by isolating the sample on NA media in 1 x 24 hour incubation at 37 ℃, the second stage was carried out by calculating the number of bacterial colonies using a CFU tool, and the third stage was carried out gram staining on the samples found gram positive bacteria. Conclusion: Based on the results of the research that has been done, it can be concluded that: at dilution of 10-6, sample 1 contains 258 bacterial colonies, sample 2 contains 93 bacterial colonies, sample 3 contains 71 bacterial colonies, sample 4 contains 25 bacterial colonies, sample 5 contains 19 bacterial colonies, sample 6 contains 905 bacterial colonies, sample 7 contains 700 bacterial colonies, sample 8 contains 511 bacterial colonies, sample 9 contains 407 bacteria, sample 7 contains 10 there 291 bacteria. Key words: Colonies, Bacterial, Dentures
IDENTIFIKASI NEMATODA USUS SOIL TRANSMITTED HELMINTH (STH) DENGAN METODE RITCHIE PADA ANAK DESA BAJO INDAH KABUPATEN KONAWE Sarkian Salsabila, Waode Ery; Idris, Sri Aprilianti; Balaka, Kemal Idris
Jurnal Analis Kesehatan Kendari Vol. 7 No. 1 (2024): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 7 (1) Desember 2024)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v7i1.336

Abstract

Intestinal worm infection is a disease caused by the entry of intestinal worms into the human body. This infection is caused by soil-transmitted helminths (STH). Indonesia is a tropical country with high humidity and has a good environment for worm breeding, especially Soil Transmitted Helminths (STH). Worm infections pose a risk to children, especially groups who occupy elementary schools. One of the causes of the risk of worms to children is soil. The purpose of this study was to determine the morphology and species of Intestinal Nematode Worm Eggs (STH) in Children using the Formol-ether Sedimentation method. This type of research is descriptive, namely to see the description and identify the results of the formalin and ether sedimentation methods. The samples used were 22 samples of feces. The results of the study on 22 samples of feces of children from Bajo Indah Village were 4 positive samples contained intestinal nematode eggs, namely Trichuris trichura, while 18 samples were negative. .
Isolasi Dan Identifikasi Bakteri Kitinolitik Pada Air Payau Menggunakan Media Kitin Dari Tulang Sotong Apriyanto; Aprilianti Idris, Sri; Rasak, Adriatman; Syahrani Ado, Marni
JKEMS- Jurnal Kesehatan Masyarakat Vol. 1 No. 1 (2023)
Publisher : Yayasan Rahmatan Fiddunya Wal Akhirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58794/jkems.v1i1.406

Abstract

Chitinolytic bacteria are a group of bacteria capable of producing chitinase enzymes. Chitinase enzyme is an enzyme that has the ability to degrade chitin. Chitinolytic bacteria can be isolated from soil and water. Brackish water is a breeding ground for chitinolytic bacteria because brackish water is a habitat for several types of chitin-producing animals such as shrimp, crabs and cuttlefish. This study aims to isolate and identify chitinolytic bacteria in brackish water. The type of research used is a descriptive experiment with the sampling technique carried out by one shot case study. From the observation of the identification of the morphology of bacteria on NA media and the results of the gram staining that has been carried out, the first sample was found to be bacteria with macroscopic characteristics of white, rhizopoid, smooth surface, flat elevation and gram-positive bacilli were found in gram staining. The second sample has morphological characteristics of white, round, smooth surface, convex elevation on gram staining found in the form of vibrio with gram negative.
Pembuatan Teh Kombucha dengan Tambahan Tanaman Herbal sebagai Minuman Probiotik Kesehatan di Desa Soropia Idris, Sri Aprilianti; Pryangan, Wulandari; Karmilah, Karmilah; Firdayanti, Firdayanti; Fusvita, Angriani; Yodha, Agung Wibawa Mahatva; Wenty, Darmayanita; Susanti, Susanti; Zeptiano, Zeptiano; Dhea, Alisha
Jurnal Pengabdian Masyarakat: Pemberdayaan, Inovasi dan Perubahan Vol 5, No 6 (2025): JPM: Pemberdayaan, Inovasi dan Perubahan
Publisher : Penerbit Widina, Widina Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59818/jpm.v5i6.2226

Abstract

Kombucha tea is the result of the fermentation of tea and sugar solution using Symbiotic Culture of Bacteria and Yeast (SCOBY) which produces a drink with a fresh taste, distinctive aroma, and contains various bioactive compounds, such as organic acids, vitamins, and probiotics. The addition of herbal ingredients to kombucha tea, such as ginger, lemongrass, or mint leaves, can enhance the taste and improve health. Soropia Village as a coastal area has great potential in the development of products based on natural ingredients. However, limited knowledge and skills of the community in processing ingredients into value-added products remain a barrier. The purpose of community service is to increase knowledge and training to the community in Soropia Village on making kombucha tea with the addition of herbs as a health drink rich in probiotics. The methods used are socialization, education, training and evaluation. This activity was carried out in Soropia Village with the target group of the Soropia Village Family Welfare Movement (PKK). This training enables the community to know and understand how to make kombucha tea with the addition of herbal plants as a health drink that can be made into a product. The training and interviews following teh kombucha tea-making workshop demonstrated that all participants understood the material, with nearly 30 participants answering the questionnaire correctly. After the training, participants were able to independently make kombucha tea with ginger at home.ABSTRAKTeh kombucha merupakan hasil fermentasi larutan teh dan gula menggunakan Symbiotic Culture of Bacteria and Yeast (SCOBY) yang menghasilkan minuman dengan cita rasa segar, beraroma khas, serta mengandung berbagai senyawa bioaktif, seperti asam organik, vitamin, dan probiotik. Penambahan bahan herbal pada teh kombucha, seperti jahe, serai, atau daun mint, dapat meningkatkan cita rasa sekaligus dapat meningkatkan kesehatan. Desa Soropia sebagai salah satu wilayah pesisir memiliki potensi besar dalam pengembangan produk berbasis bahan alami. Namun, keterbatasan pengetahuan dan keterampilan masyarakat dalam mengolah bahan menjadi produk bernilai tambah masih menjadi kendala. Tujuan pengabdian untuk meningkatkan pengetahuan dan pelatihan kepada masyarakat di desa soropia tentang pembuatan teh kombucha dengan tambahan herbal  sebagai minuman kesehatan yang kaya probiotik. Metode yang digunakan adalah sosialisasi, edukasi, pelatihan dan evaluasi. Kegiatan ini dilaksanakan di desa soropia dengan target kelompok PKK desa Soropia. Pelatihan ini membuat masyarakat dapat mengetahui dan memahami bagaimana cara pembuatan teh kombucha dengan tambahan tanaman herbal sebagai minuman kesehatan yang dapat dijadikan produk. Hasil pelatihan dan wawancara setelah dilakukan pengabdian pembuatan teh kombucha, seluruh peserta memahami materi yang diberikan dengan hasil jawaban hampir 30 peserta menjawab kuesioner dengan benar. Setelah pelatihan, peserta dapat membuat teh kombucha dengan tambahan jahe secara mandiri dirumah.
Skrining Senyawa Metabolit Sekunder Ekstrak Daun dan Kulit Batang Bruguiera gymnorrhiza dari Laguna Anano Te’i, Buton Tengah Maharani Maharani; La Ode Abdul Fajar Hasidu; Raodatul Jannah; Melati Octapian Simanjuntak; Kasnia Kaatu; Indra Ardiansyah; Sri Aprilianti Idris; Agung Wibawa Mahatva Yodha
Journal of Marine Research Vol 14, No 4 (2025): Journal of Marine Research
Publisher : Departemen Ilmu Kelautan, Fakultas PerikanJurusan Ilmu Kelautan, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jmr.v14i4.53760

Abstract

Ekosistem mangrove kaya akan senyawa metabolit sekunder yang memiliki nilai ekologis dan farmakologis. Bruguiera gymnorrhiza merupakan salah satu spesies mangrove dominan yang telah lama dimanfaatkan dalam pengobatan tradisional, namun profil bioaktifnya pada habitat unik masih jarang dikaji. Penelitian ini bertujuan mengetahui komposisi kualitatif dan kuantitatif bioaktif pada daun dan batang B. gymnorrhiza dari Laguna Anano Te’i, Buton Tengah. Sampel diekstraksi dengan metode maserasi menggunakan etanol, kemudian dilakukan skrining fitokimia dan kuantifikasi spektrofotometri. Analisis kualitatif menunjukkan keberadaan alkaloid, flavonoid, steroid, dan fenolik pada kedua bagian tanaman. Secara kuantitatif, daun mengandung fenolik sebesar 465,596 mg GAE/g ekstrak, steroid 275,794 mg CE/g, alkaloid 83,944 mg CE/g, dan flavonoid 6,501 mg QE/g. Kulit batang didominasi oleh steroid sebesar 362,745 mg CE/g, diikuti fenolik 149,807 mg GAE/g, alkaloid 25,889 mg CE/g, dan flavonoid 6,419 mg QE/g. Variasi ini menunjukkan adanya pengaruh lingkungan laguna terhadap biosintesis senyawa metabolit sekunder, dengan daun memiliki potensi lebih besar sebagai antioksidan dan antimikroba. 
Platelet to cholesterol ratio of high density lipoprotein cholesterol is associated with diabetes and comorbidity risk Ani Umar; Firdayanti; Heni Umar; Angriani Fusvita; Susanti; Sri Aprilianti Idris
Gema Lingkungan Kesehatan Vol. 24 No. 2 (2026): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v24i2.452

Abstract

This study aims to analyze the relationship between platelet to HDL cholesterol (Platelet to HDL Ratio / PHR) ratio and the presence of type 2 diabetes mellitus, as well as evaluate the ability of PHR as a predictor of comorbidity risk. Multivariate logistic regression analysis was used to estimate the odds ratio (OR) and 95% CI. The discriminatory ability of the model is evaluated with the receiver operating characteristic curve (ROC), with the area under the curve (AUC) used to measure the model's performance. Sensitivity and specificity. This study used a cross-sectional observational design with 220 participants (110 type 2 diabetes patients and 110 non-diabetic controls) from the Southeast Sulawesi Provincial General Hospital. Samples were selected based on inclusion criteria (age 30–70 years, for the diabetes group) and exclusion (such as anemia or use of anticoagulant drugs). Data were collected through clinical examinations (age, BMI, blood pressure, platelet count, HDL). PHR is calculated as the number of platelets (per μL) divided by HDL levels (mg/dL). Statistical analysis was performed using independent t-test, multivariate logistic regression, and ROC curve with SPSS software (p < 0.05). The results showed that PHR was significantly higher in the diabetes group with comorbidities (mean 5.49±2.10) than in healthy individuals (4.25±2.39; p < 0.001). The ROC curve shows an AUC of 0.70 for PHR in predicting comorbidity risk, better than HDL alone (AUC 0.55). This study shows that platelet-to-HDL ratio (PHR) is proven to be a simple and economical potential biomarker for detecting an association with diabetes and predicting the risk of vascular comorbidities. These findings support the use of PHR in routine clinical practice, especially in developing countries such as Indonesia. This research contributes to the strategy for the early prevention of diabetes complications through easily accessible hematological parameters.
Gambaran Kalsium Urin pada Lanjut Usia Warga Tobuha Kecamatan Puuwatu Kota Kendari Muhamma Sultanul Aulya; Siti kaylah; Sri Aprilianti Idris; Firdayanti; Ani Umar
coba Vol 14 No 2 (2026): Mei 2026
Publisher : Akademi Keperawatan Dharma Husada Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32831/jik.v14i2.1016

Abstract

Pendahuluan: Kadar kalsium urin yang tinggi dapat disebabkan oleh peningkatan absorpsi kalsium di saluran cerna atau penurunan deposisi kalsium ke dalam tulang. Kondisi tersebut dapat meningkatkan kadar kalsium dalam darah yang selanjutnya diekskresikan melalui urin. Lansia merupakan kelompok yang rentan mengalami perubahan metabolisme kalsium akibat proses penuaan. Penelitian ini bertujuan untuk mengetahui gambaran kadar kalsium urin pada lansia di Jalan Perkuburan, Kecamatan Puuwatu. Metode: Penelitian ini menggunakan desain deskriptif. Sampel penelitian terdiri atas 33 sampel urin lansia yang berdomisili di Jalan Perkuburan, Kecamatan Puuwatu. Pemeriksaan kadar kalsium urin dilakukan secara kualitatif menggunakan metode Sulkowitch melalui reaksi pengendapan kalsium dengan reagen Sulkowitch. Sampel urin dikumpulkan pada pagi hari dan dianalisis sesuai prosedur pemeriksaan. Hasil: Hasil pemeriksaan menunjukkan bahwa dari 33 responden, sebanyak 7 orang (21,2%) memperoleh hasil negatif, sedangkan 26 orang (78,8%) memperoleh hasil positif kalsium urin berdasarkan metode Sulkowitch. Kesimpulan: Sebagian besar lansia di Jalan Perkuburan, Kecamatan Puuwatu menunjukkan hasil positif kalsium urin berdasarkan pemeriksaan metode Sulkowitch. Temuan ini menunjukkan tingginya proporsi lansia dengan hasil positif kalsium urin sehingga diperlukan penelitian lanjutan menggunakan metode kuantitatif untuk mengukur kadar kalsium urin secara lebih akurat serta mengidentifikasi faktor-faktor yang memengaruhinya. Kata Kunci : Kalsium Urin, Lanjut Usia, Warga Perkuburan.