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All Journal NALARs Prosiding Semnastek International Journal of Advances in Intelligent Informatics Nature: National Academic Journal of Architecture Elektum : Jurnal Teknik Elektro International Journal of Built Environment and Scientific Research Swabumi (Suara Wawasan Sukabumi) : Ilmu Komputer, Manajemen, dan Sosial IJCIT (Indonesian Journal on Computer and Information Technology) AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat SAMARAH: Jurnal Hukum Keluarga dan Hukum Islam RESISTOR (Elektronika Kendali Telekomunikasi Tenaga Listrik Komputer) Jurnal Permukiman Acuity : Journal of English Language Pedagogy, Literature and Culture MULTINETICS Jurnal PORKES Jurnal Pengabdian Masyarakat Teknik Emanasi Jurnal Ilmu Keislaman dan Sosial Jurnal Koridor Jurnal Kajian Ilmiah Journal of Tourism and Economic Dedikasi: Jurnal Pengabdian kepada Masyarakat Instal : Jurnal Komputer Simpatik: Jurnal sistem Informasi dan Informatika J-Intech (Journal of Information and Technology) Jurnal Insan International Journal of Architecture and Urbanism Al-Istinbath: Jurnal Hukum Islam Nuansa Informatika Journal of Entrepreneurship and Community Innovations INTERNATIONAL JOURNAL OF SOCIETY REVIEWS (INJOSER) La-Tahzan: Jurnal Pendidikan Islam RESLAJ: Religion Education Social Laa Roiba Journal Profetik: Jurnal Pengabdian Masyarakat Islamic Education Journal (ISEDU) Language Circle : Journal of Language and Literature At Tawil Jurnal Pengkajian al Quran dan at Turats
Saeful Bahri
(Scopus Author ID: 57216680383) Universitas Muhammadiyah Jakarta
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Journal : Nuansa Informatika

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Feature Extraction Using Markov Random Field (MRF) On Improving CNN Classification Results For Alzheimer's Disease Diagnosis: Ekstraksi Fitur Menggunakan Markov Random Field (MRF) untuk Meningkatkan Hasil Klasifikasi CNN pada Diagnosis Penyakit Alzheimer Bahri, Saeful; Adiwisastra, Miftah Farid; Hidayatulloh, Taufik
NUANSA INFORMATIKA Vol. 19 No. 2 (2025): Nuansa Informatika 19.2 Juli 2025
Publisher : FKOM UNIKU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25134/ilkom.v19i2.369

Abstract

Alzheimer’s disease is a degenerative neurological disorder that significantly affects patients’ cognitive functions and social lives. It is a leading form of dementia, characterized by the progressive death of brain cells. One widely adopted diagnostic approach involves magnetic resonance imaging (MRI) to evaluate brain structures. Recent advances in machine learning have enabled automated image analysis, with Convolutional Neural Networks (CNNs) commonly used for image feature extraction and classification. However, CNNs face a major limitation in maintaining consistency during image segmentation, which results in reduced classification accuracy. This issue arises from CNNs’ limited ability to preserve local pixel-level consistency during feature extraction. To address this, we propose integrating a Markov Random Field (MRF)-based layer into the CNN architecture, which has been shown to enhance segmentation consistency. This study utilizes publicly available MRI datasets of Alzheimer’s patients and employs a k-fold cross-validation scheme for evaluation. The results show that the CNN-MRF model improves classification accuracy to 63%, compared to 61% with the standard CNN. Furthermore, the loss value is reduced from 0.80 to 0.74. Although the improvement in accuracy is incremental, a paired t-test confirms that the difference is statistically significant (p < 0.05). This method has proven effective in enhancing the reliability of image-based diagnostic systems for early detection of Alzheimer’s disease.
Co-Authors Achmad Fauzi Agus Sutisna Ahmad Nur Faizin Ahmad Yusuf Al-Amin, Roby Andhika Darmawan Andi Riyanto Andi Zulfa Majida Andia Ridho Arif Anggraini, Recha Abriana Anisa Anisa Arafah, Sitti Ari Widyati Purwantiasning Ari Widyati Purwantiasning Arief, Dasya As. Rakhmad Idris, As. Rakhmad Asep Saefullah Ashadi Buana, Muhammad Cakra Chairul Anwar Dede Burhanudin, Dede Dede Wintana Eka Ratna Safitri Endang Juliastuti Erwin Dermawan Fadillah Rezky, Syarifah Fadliondi Faris, Nahrul Febby Angga Permana, Febby Angga Fikriyah, Kholisotu Giriana, Dewinta Firda Gunawan Gunawan Gunawan Habibah, Nurul Fitri Hardivizon Hardivizon Haris Isyanto Heri Kusindaryadi Husnibes Muchtar Husnibes Muchtar Iqbal Fadhilah Jihan Sonia Khaerurani Nur Asyifa Kokom Komariah Kumala Sari, Eva Dwi Kusmira, Mira Mahmudah Nur, Mahmudah Masitoh, Rikha Masyitoh Melisa Winda Pertiwi Miftah Farid Adiwisastra Miftahul Janah Mochamad Noorman Bayuardi Moh.Badrul Alam Muhamad Rosadi, Muhamad Muhammad Akbar Rafsyanjani Muhammad Cakra Buana Muhammad Fachri Baharsyah Muhammad Hidayat Nur Wahid Muhammad Miftahussalam Musyfikah Ilyas, Musyfikah Mutawakkil, Muhammad Pasya Nanda Alifia Nasruhi, Moch. Nugraha, Setyo Bagus Nurohmah, Siti Pangestu, Agis Panggalih Sako Denta Pindha Kaptiningrum Pribadi, Denny Purwono Purwono Putra Arista Pratama, Putra Putra Septia Yuza Qur'ani, Tsaura Halwa Rafsyanjani, Muhammad Akbar Ratningsih, Ratningsih Ridwan ridwan Riza Samsinar Rizal Amegia Saputra Rizka Amalia Rusda Wajhillah, Rusda Ruslan Abdul Gani Satia Suhada, Satia Setiawan, Sandy Sinta Nur Hilali Sinuraya, Junus SITI KHOLIFAH Sri Endah Wahyuningsih Sri Wuli Fitriati Stefani Kusuma Dewi Suhardiyanto Suhardiyanto, Suhardiyanto Sulaeman, Hamdun Sumarno, Ardawi Suprijanto Suprijanto Sururi Syibromalisi, Arif Taufik Hidayatulloh Tuffahati, Wafa W, Widhiyanto Wardany, Mutia Setya Widayati Yanti Apriyani, Yanti Yogi Haryono Yulianto Yuri Rahayu Ziaul Fiqih, Ziaul