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Journal : Universa Medicina

Effect of cross-running polypropylene intradermal suture technique on keloid scar: a single-blind randomized controlled trial Wihastyoko, Herman Yosef Limpat; Rinhastyanti, Edith Sumaregita; Arviansyah, Arviansyah; Siswanto, Yudi; Agustina, Wilma; Sintaningrum, Elisabeth Prajanti
Universa Medicina Vol. 45 No. 1 (2026): Aheaf Of Print
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2026.v45.4-12

Abstract

BACKGROUNDKeloids are abnormal scars that present a therapeutic challenge. Various treatment modalities have been developed, including surgical excision. While cross-running intradermal sutures were previously created using absorbable polyglycolic acid, this study introduces a modification using a non-absorbable material. Therefore, this study aimed to evaluate the effect of the cross-running polypropylene intradermal suture (CR-PIS) technique compared to the simple interrupted suture technique on keloid repair. METHODSThis was a randomized controlled trial with a post-test-only design involving 30 male and female keloid patients aged 20-50 years. Participants were randomized into the treatment group (n=15) and the control group (n=15). Wound assessment using the Vancouver Scar Scale (VSS), Manchester Scar Scale (MSS), and Patient and Observer Scar Assessment Scale (POSAS) was performed at 3, 6, and 9 months after surgery. Differences in VSS, MSS, and POSAS scores between the CR-PIS group and the simple knot group were analyzed using the Mann-Whitney U test. RESULTSStatistical analysis revealed a significant difference between the simple knot and CR-PIS groups (p<0.05). The median scores for each assessment (VSS, MSS, and POSAS) decreased significantly at 3, 6, and 9 months, with the control group's values being higher than those in the CR-PIS group (p<0.05). These results indicate that the control group developed moderate scars, whereas the treatment group exhibited good scars. CONCLUSIONSThe CR-PIS is more effective than the simple knot technique in improving keloid scars, as shown by changes in wound appearance, morphological function, topography, and patient and evaluator assessments.
Co-Authors Abdul Malik Abdul Rahmat Agustina, Wilma Akbar, Riven Alfafa, Abduh Malik Aliyah, Khotimatul Amiruddin Amiruddin Amiruddin Amrul, Hanifah Mutia Zaida Ningrum Angga Bahri Pratama Ariksa, Jeri Arviansyah, Arviansyah Astuti, Dwi Hari Auliya, Faiza Fardha Azizah, Markhamah Watianur Bagus Kisworo, Bagus Bela, Ardila Dinda Salsa Cahyani, Arini Dwi Diva Pramesti Putri Dyah Ayu Wulandari Erwin Nyak Akoeb, Erwin Nyak Fachry Abda El Rahman Fadia Talia Salsabila Hervi Fathurrasuli, Fathurrasuli Fikrah Dian Indrawati Sawali Hendi Lilih Wijayanto Hidayah, Sunnatul Hidayat Hidayat Hutagalung, Magda Rosalina Ika Nurjannah, Ika Ilyas Ilyas Ilyas, I. Ilyas, I. Imam Shofwan Indarthi, Anifah Widya Indri Lakhsmi Putri, Indri Lakhsmi Irvan, Moh. Farizqo Isa, Abd. Hamid Ismail, Muhammad Azri Ismaniar Ismaniar Joko Sutarto Jusuf Sjamsudin Kadriadi, Kadriadi Limpat Wihastyoko, Herman Yosef Miftahul Khair Mintarsih Arbarini MITA RAHMAWATI Moh. Azhar Afandy Muhammad Alfian, Muhammad Nurcahyaningsih, Caturinta Nusantara, Bobby Ardhian Perdana, Andika Permadi, Mhd Bambang Prasetyaningtyas, Fitria Dwi Prilianti, Ratna Putra, Eriek Aristya Pradana Riduwan Riduwan, Riduwan Rinhastyanti, Edith Sumaregita Ristiana, Nanda Saputra, Aditiyo Tri Saragi, Jandri Fan HT Setiarto Pratigto Setiawan, Angga Tegar Sintaningrum, Elisabeth Sintaningrum, Elisabeth Prajanti Siswoyo, Devira Sungkowo Edy Mulyono Syaifuddin, Muh Tanjaya, Krisanto Tri Joko Raharjo Tri Suminar Urrofik, Safira Arbella Aurell Utsman, U. Utsman, U. Wihastyoko, Herman Wihastyoko, Herman Yosef Limpat Wijayanto, Hendi Lilih Wirakusuma, Kadex Widhy Wruhastanti, Gisella S. Wruhastanti, Gisella Sekar Yoshehira, Orien Yusdianto Yusdianto Zamriyetti, Zamriyetti