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Journal : Odonto dental journal

ROLE OF COMBINATION CASEIN AND LACTOFERRIN BOVINE’S COLLOSTRUM AS A PULP CAPPING ON MACROPHAGE EXPRESSION IN MALE WISTAR RATS Endah Ariyati Eko Ningtyas; Oedijani Santoso; Udadi Sadhana; Siti Sunarintyas
Odonto : Dental Journal Vol 8, No 2 (2021): December 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (319.67 KB) | DOI: 10.30659/odj.8.2.156-164

Abstract

ABSTRACTBackground: Inflammatory and/or non-inflammatory processes play a role in stimulating pulp repair and the formation of hard tissue, namely reparative dentin. Macrophages play a role in the pathogenesis and chronic inflammatory disorders. The combination casein lactoferrin of bovine colostrum as an immunomodulator has therapeutic potential. This study aims to determine the therapeutic effect and duration of application of the combination of casein lactoferrin of bovine colostrum, on the expression of macrophages as pulp capping.Method: This study was a true experimental laboratories post test only control group design, consisting of three groups of 60 male wistar rats with 4 observation times, namely day to day 7, 14, 21 and 28 each of 5 mice. The maxillary 1st molars were prepared until the roof of the pulp was exposed. Three groups, namely the combination of casein and lactoferrin bovine colostrum (CKL) and calcium hydroxide (K1) and the untreated group (K0). Each group was filled with glassionomer as a permanent restoration. The tissue was made histological preparations with hematoxylin-eosin staining and the number of macrophages were counted, then analyzed by two way ANOVA and post hoc LSD tests.Result: The results showed that the therapeutic effect and duration of application of the combination of casein and lactoferrin bovine colostrum on the expression of macrophages as pulp cappingConclusion: The combination of casein and lactoferrin of bovine colostrum as capping material can increase the number of macrophages in the healing process of dental pulp.
Comparison of bombyx mori l. Fibroin coatings on the mechanical properties of collagen membranes Fathurrahman, Helmi; Sunarintyas, Siti; Barunawati, Sri Budi; Nuryono, Nuryono
Odonto : Dental Journal Vol 10, No 1 (2023): July 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.10.1.146-151

Abstract

Background: Most of dental implants are accompanied by guided bone regeneration (GBR) procedures. Collagen membrane which is the most widely used type of membrane in the GBR procedure has the disadvantage of not having antimicrobial properties, old bone formation, easy to tear, and soft so that it does not maintain the dimensions of the augmentation area. Bombyx mori L. fibroin has good mechanical properties and has the potential to be used as a pharmaceutical material that is biocompatible, antimicrobial, and stimulates bone growth. The aim of this study was to analyze the effect of Bombyx mori L. fibroin coating on the mechanical properties of collagen membranes. Method: The samples consisted of the control group (group A) and the treatment group, the collagen membrane was coated using the Bombyx mori L dip-coating fibroin technique, namely group B (1 time coating process), group C (2 times coating process) and group D (3 times the coating process). Statistical analysis used one-way ANOVA (p
Co-Authors Abdulghani Ali Khalil Afra Hatim Ahmad Syaify, Ahmad Akmal, Syazwani Alizatul Khairani Hasan Alva Edy Tontowi Ananto Ali Alhasyimi Archadian Nuryanti Aria Fransiska Asam Khalifa Mohammed Asam Khalifa Mohammed Dahlia Herawati Dea Cahyani, Yessica Dedi Sumantri Dewi Agustina Dian Noviyanti Agus Imam Dian Noviyanti Agus Imam, Dian Noviyanti Agus Dita Ayu Mayasari, Dita Ayu Dyah Anindya Widyasrini Dyah Irnawati Ema Mulyawati Ema Mulyawati Ema Mulyawati Endah Ariyati Eko Ningtyas Fery Setiawan Harsini Harsini ,, Harsini Hasna Syifa Yuniva Helmi Fathurrahman, Helmi Heni Susilowati Hilda Mutia Hanum I Dewa Gde Mayun Permana Iwa Sutardja, Iwa Iwa Sutardjo Iwa Sutardjo, Iwa Jukka Pekka Matinlinna Juni Handajani Karina Larasati Khuzaimah, Ismi Lisdrianto Hanindriyo Lukis, Prima Agusti Margareta Rinastiti mariyam mariyam, mariyam Marsetyawan HNE Soesatyo Marsetyawan HNE Soesatyo Marsetyawan HNES Mochammad Imron Awalludin Mohammad Khafid Muhammad Kusumawan Herliansyah N Nuryono Nilasary Rochmanita Suparno Nuryono Nuryono Nuryono Nuryono Nuryono Nuryono Nuryono Nuryono Oedijani Oedijani, Oedijani Paramarta, Sagita Pradnya Pinandi Sri Pudyani Prakosa, Basma Rosandi Pramudya Aditama Prisca Dhyaning Dentiana R. Rachmat A Sriwijaya Rahma Syarafina Maharani Rahman, Friska Ani Raymund Octavius Kusuma Buwana Rifki Moechtar Rini Dharmastiti Rosyida, Niswati Fathmah Sana Mohammed Alrefae Sri Budi Barunawati Sri Kavi Subramaniam Sudarsono Sudarsono Sudibyo Martono Sumantri, Dedi Suparyono Saleh Suryono Suryono , Syazwani Akmal Tunjung Nugraheni Udadi Sadhana, Udadi Verani, Dhea Maurilla W. Widjijono Wayan Tunas Artama Widowati Siswomihardjo Widowati Siswomiharjdo Widowati Siswomiharjo Widowati Widowati Widya Asmara Widya Asmara Widya Puspita Sari Widya Puspita Sari Yasnawi, Mohammad Imanuddin Yeni Yustisia Yoga, I Gede Krisna Merta Yosi Bayu Murti Yuliatun, Leny Yulita Kristanti