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All Journal Journal of Information Systems Engineering and Business Intelligence MPI (Media Pharmaceutica Indonesiana) JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA E-Dimas: Jurnal Pengabdian kepada Masyarakat Manuju : Malahayati Nursing Journal JFIOnline Journal of Telenursing (JOTING) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Komunitas Linggau Journal Science Education (LJSE) Jurnal Bakti Untuk Negeri Journal of Public Health and Pharmacy Borneo Journal of Pharmacy
Yunita Nita
Departemen Farmasi Praktis, Fakultas Farmasi, Universitas Airlangga
Chemistry Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Karakteristik Pasien Gangren Diabetik di Rumah Sakit Sulistiya Ningsih; Yunita Nita; Yuni Priyandani
Malahayati Nursing Journal Vol 6, No 9 (2024): Volume 6 Nomor 9 (2024)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v6i9.15567

Abstract

ABSTRACT Indonesia was ranked sixth in the world in terms of deaths due to diabetes mellitus in 2021. Gangrene is tissue death due to blockage of blood vessels that provide nutrients to those tissues and is a form of complication of diabetes mellitus. Diabetic gangrene can occur in every part of the body that is lowest, especially in the lower extremities. Diabetes mellitus in an advanced time will cause complications of angiopathy and neuropathy which are the basic causes of gangrene. This study aims to determine the characteristics of diabetic gangrene patients at dr. Mohammad Zyn Sampang Hospital based on demographic data. This study is an analytical research with an observational design through a cross-sectional approach. The population of this study is all patients with a diagnosis of diabetes mellitus with gangrene in the inpatient period from March 1 to July 31, 2023. Sampling uses the total sampling technique or saturated sampling, which is a sampling technique when all populations are used in the study which aims to obtain generalizations with a very small error rate. Data analysis uses SPSS version 25 descriptive analysis. There are a total of 96 samples of inpatient diabetic gangrene patients. The results of the study were obtained by the characteristics of the majority of diabetic gangrene patients who were female with a total of 56 (58.3%)  in the age range of 51 – 60 years with a total of 33 (34.4%), the level of elementary education / equivalent became the highest level of education by 33 (34.4%) and working as housewives with a total of 41 (42.7%). The conclusion of this study is that the female gender is elderly, with the level of elementary education / equivalent is a characteristic and works as a housewife, most commonly found in diabetic gangen patients at dr. Mohammad Zyn Sampang Hospital. Keywords: Diabetic Gangrene, Gender, Age, Education Level, Occupation  ABSTRAK Indonesia menduduki peringkat keenam kasus kematian akibat diabetes melitus di dunia pada tahun 2021. Gangren adalah kematian jaringan karena obstruksi pembuluh darah yang memberikan nutrisi ke jaringan tersebut dan merupakan salah satu bentuk komplikasi dari penyakit diabetes melitus. Gangren diabetik dapat terjadi pada setiap bagian tubuh yang terendah terutama pada ekstremitas bawah. Diabetes mellitus dalam waktu yang lanjut akan menyebabkan komplikasi angiopathy dan neuropathy yang merupakan penyebab dasar terjadinya gangren. Penelitian ini bertujuan untuk mengetahui karakteristik penderita gangren diabetik di RSUD dr. Mohammad Zyn Sampang berdasarkan data demografi. Penelitian ini merupakan penelitian analitik dengan rancangan observasional melalui pendekatan cross-sectional. Populasi penelitian ini adalah seluruh pasien dengan diagnosis diabetes melitus dengan gangren  di rawat inap periode 1 Maret sampai dengan 31 Juli 2023. Pengambilan sampel menggunakan teknik total sampling atau sampling jenuh yaitu teknik penentuan sampel apabila semua populasi digunakan dalam penelitian yang bertujuan agar didapatkan generalisasi dengan tingkat kesalahan yang sangat kecil. Analisis data menggunakan analisis deskriptif SPSS versi 25. Total terdapat 96 sampel pasien gangren diabetik rawat inap. Hasil penelitian didapatkan karateristik mayoritas pasien gangren diabetik berjenis kelamin perempuan dengan jumlah 56 (58,3%) pada rentang usia  51 – 60 tahun dengan jumlah 33 (34,4%), tingkat pendidikan SD/Sederajat menjadi jenjang pendidikan terbanyak sebesar 33 (34,4%) dan bekerja sebagai ibu rumah tangga dengan jumlah sebesar41 (42,7%). Kesimpulan penelitian ini adalah jenis kelamin perempuan yang berusia lanjut, dengan tingkat pendidikan SD/Sederajat merupakan karakteristik dan bekerja sebagi ibu rumah tangga, paling umum yang ditemukan pada pasien gangen diabetik di RSUD dr. Mohammad Zyn Sampang. Kata Kunci: Gangren Diabetik, Jenis Kelamin, Usia, Tingkat Pendidikan, Pekerjaan
Evaluation of Pharmacist-Based Services for Type 2 Diabetes Mellitus in the Indonesian Community Health Centers Riza Alfian; Yunita Nita; Umi Athiyah
Journal of Public Health and Pharmacy Vol. 5 No. 1 (2025)
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v5i1.5888

Abstract

Introduction: Diabetes mellitus is a global epidemic that continues to rise, including in Indonesia, and it has significant impacts on public health. The role of pharmacists in providing pharmaceutical care for diabetic patients in community health centers is crucial, yet challenges in its implementation persist. However, in-depth studies on pharmacists' practice experiences in this context are still limited in Indonesia. This study aimed to explore pharmacists' experiences in implementing pharmaceutical care for diabetic patients at community health centers in Indonesia. Methods: The cross-sectional study was conducted in community health centers in South Kalimantan Province, Indonesia. Pharmacists practicing at community health centers were recruited between October and December 2023. The survey was distributed in both paper and online (Google Form) formats. The questionnaire used in the survey focused on the provision of assessment, care plan, and follow-up parameters regarding the medication of diabetic patients. Results: A response rate of 60,3% (n=143) was obtained from pharmacists involved in this survey. Regarding the assessment parameter, the indicator of assessment patient trust was the most dominant implemented by pharmacists (93,7%) compared to other indicators. In terms of the care plan parameter, providing information on medication indications was the most dominant indicator implemented (82,9%). Meanwhile, for the follow-up parameter, the indicator of medication adherence follow-up was the most dominantly implemented by pharmacists (79,1%). Factor analysis revealed that assessment, care plan, and follow-up evaluation each constituted one composite. Conclusion: The pharmaceutical care provided by pharmacists at community health centers for diabetic patients is still suboptimal. The factors that caused the suboptimal implementation of pharmaceutical care were resource limitations, inadequate specialized training for pharmacists, and insufficient support from the healthcare system.
A Systematic Review: Cost-Effectiveness of SGLT2 Inhibitors versus DPP-4 Inhibitors as Add-on to Metformin Izzatu Al Hanifiyah; Yunita Nita; Libriansyah; Achmad Ridwan
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 12 No. 2 (2025): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v12i22025.256-263

Abstract

Background: The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. Sodium-glucose cotransporter-2 inhibitors (SGLT2i) and dipeptidyl peptidase-4 inhibitors (DPP-4i) are two second-line therapy alternatives for T2DM patients inadequately controlled with metformin. Objective: This study aimed to systematically review the cost-effectiveness of combining metformin+SGLT2i vs metformin+DPP-4i for T2DM treatment. Methods: A systematic search was conducted in PubMed, Scopus, and ScienceDirect for articles published between 2015-2025, using predefined keywords and following the PRISMA and PICOS frameworks (P: T2DM patients uncontrolled on metformin monotherapy; I: Metformin+SGLT2i therapy; C: Metformin+DPP-4i therapy; O: Cost, clinical outcomes (HbA1c% reduction), Incremental Cost-Effectiveness Ratio (ICER) values, Quality Adjusted Life Years (QALY); S: Study with cost-effectiveness analysis design). Additional studies were identified through reference screening. Eligible articles were independently reviewed and assessed for reporting quality using the CHEERS-2022 standards. Results: Five studies met the inclusion criteria. Considerable heterogeneity was observed with mean patient ages ranging from 55-61 years old and baseline HbA1c levels from 7.9%-9.4%. The studies were conducted in the US, UK, Mexico, and Greece, all funded by the pharmaceutical industry, and used economic models. Despite these differences, all studies consistently demonstrated that combining metformin+SGLT2i was more cost-effective than metformin+DPP-4i. SGLT2i improved the quality of life by 0.032–0.04 QALYs, reduced hypoglycemia, and provided additional benefits for patients with cardiovascular risk, although it was associated with higher initial costs. Conclusion: This review showed that the combination of metformin+SGLT2i was more cost-efficient and effective in managing T2DM than the combination of metformin+DPP-4i.
Cost of Illness of Diabetic Foot Ulcer in Lower Middle-Income Countries: A Systematic Review Sinta Wulandari; Alfadea Irbah Allizaputri; Libriansyah; Yunita Nita
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 13 No. 1 (2026): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v13i12026.72-83

Abstract

Background: Diabetic foot ulcers (DFU) are a consequence of diabetes mellitus (DM) that cause a significant financial burden on the healthcare system, society, and individuals. The average prevalence of DFU was 6.3%. The cost of diabetic foot care is 50% to 200% higher than that of primary diabetes care. Objective: This systematic review aimed to provide an overview of the variations in the economic burden of DFU in lower middle-income countries (LMICs). Methods: This systematic review examined studies published in English that investigated the costs associated with evaluating diabetic foot disease in LMICs. COCHRANE, CINAHL, DOAJ, EMBASE, GOOGLE SCHOLAR, Ovid MEDLINE, PUBMED, SCIENCE DIRECT, and SCOPUS were used as literature sources without publication date restrictions. Results: A systematic search identified six eligible studies conducted across multiple countries. The studies were published between 2000 and 2024, with study durations ranging from 6 to 12 months. These studies showed large variations in cost components, estimating both direct and indirect costs of the disease. The total costs incurred for DFU vary among LMICs, ranging from USD 379.39 to USD 60,014.81 per year. Conclusion: DFU impose a significant economic burden in LMICs, with substantial variations in cost estimates owing to differences in methodology and data availability. Future studies on the cost burden of DFU should be conducted on a larger scale to obtain more accurate cost estimates.
Co-Authors A. A. Rai Mas Feby Kumala Dewi Aanisah Nabiilah Abby Rahmat Kamaruzzaman Abdul Rahem Abdul Rahem Abdul Rahem, Abdul Achmad Ridwan Adinda Siti Almirah Fatima Aina Senja Yuliyani Aisyia Aisyia Ajeng Ambar Sari Alfadea Irbah Allizaputri Alfiana Istighfarin Alfira Maulidyah Rahmah Alisa Sari Nastiti Alvina Dewi Astuty Alysa Intan Santika Amanda, Natasya Noor Amelia Ghaisani Ana Yuda Ananda Indzar Kholilah Ananda, Yussi Anatasya Andini Setiawan Andi Hermansyah Andi Hermansyah Andika Fajar Fortuna Dhonny Kusuma Andreas Bayu Eka Wijayanto Andwynanda Bhadra Nareswari Andyko Ismareka Putra Angeline Tirza Galuh Palupi Anisa Maulidi Syavira Anisah Febrian Rahmawati Anita Nur Azizah Annisa Febriani Putri Aprilia Purwita Arie Sulistyarini As Sulton, Alfiansyah Maulana Aswarliansyah Athaya Bella Azzahrya Ayu Dewi Sartika Ayu Larasati Azza Maulidia El Java Azzalin Devariany Mufidah Bambang Subakti Z Bella Rizkia Dianita Byandra, Naila Cordellia Calista Amelia Devinta Julian Tupenalay Devita Ivana Putri Dewi Fatima Auzianingrum Muntari Diah Ayu Wakita Trimanda Diajeng Putri Kinanti Diamita, Bernardina Dian Parwati Dihan Asnafin Fadhila Dina Syauqina Hamid Dinara Fathya Rahma P Ditha Carolina Emanuella Dwi Rekno Ningrum Dyandra Anjani Putri Elian Haris Darmawan Elida Zairina Elsa Ananda Setya Budi Farhan Athallah Rafif Fauziyyah Labibah Febria Tri Erliana Firdaus, Favian Rafif Firman Wahyudi Friesca Surya Nurhaidah Gamar, Fahmi Haitsami Ibnu Gesnita Nugraheni Gusti Noorrizka V Gusti Noorrizka Veronika Ahmad Hamidah, Nabilah Nur Hana Sofiana Maghfira Hasna, Safina Hanifa Helmy Kurniawan Hermansyah, Andi I NYOMAN WIJAYA Ihda Nuril Fitriani Iim Suhaemi, Iim Ike Septi Marinda Indah Pratiwi Aryani Ira Puspitasari Izzatu Al Hanifiyah Jamhari Jamhari Jessica Febe Prawadi Kambarwati Nur Shofa Kevin Hermawan Hutahaean Khintan Rizky Fadhila Kresnamurti, Angelica Kristiani, Ananda Dwi Laras, Kirana Sekar Lestiono Lestiono Lestiono Lestiono Libriansyah Libriansyah Libriansyah Libriansyah Libriansyah Lichijati Lichijati Luthfia Hany Primadani M Aqbil Izzul Haq Mahanggi, Oktarina Maldini, Cindy Andrifo Marensa Faradilla Mareta Rindang Andarsari Marita Belia Putri Mochammad Haris Firdaus Mufarrihah, Mufarrihah Muhammad Noor Diansyah Muhammad Rizky Muhammad Thariq Nadhafi Muhammad Zaesal Rizki Muzaffar Musdar, Tamzil Azizi Nada Aprilliya Nadhira Mileni Tsalitsia Nadilah Sobrina Zakiroh Nafi' Nur Hidayah Nafisah Putri Syaharani Najmi MY. Tunggeng Nasywa Ekgi Cahyani Neva Safitri Salsabila Ni Putu Widya Sriastuti Noer Aqiel Natsier Noor Baihaqi, Reihan Ananta Noorrizka, Gusti Nursanti Arya Pratiwi Oktarina Mahanggi Pratiwi, Kusma Ayu Purwitasari, Neny Putri Amelia Rooswita Putri Anggi Aprilia Marcelina Putri, Fida Roesdiana Putri, Sonia Anggitha Rahmadi Wahyu Bowolaksono Rahmawati, Diana Aulia Ridka Aulia Santi Ridzhan Mawasa Rini Ayu Agustin Riza Alfian Rizdamaya Lintang Herfadanti Rosinta Dewi Anggraeni Rossika Rachmafebri Salsabila Khairunnisa Salsabilla Madudari Kasatu Sapna Rizka Salsabila Sari, Febrina Kurnia Seisye Junita Miru SETIAWAN, Catur Dian Setyawan, Rr. Elmira Shafira Dwita Anugrah Sidiq, Kadavi Arafat Silalahi, Zavirah Sinta Wahyu Nur Muthi Sinta Wulandari Siti Sarah Suhaemi, Iim Sulistiya Ningsih Sylvia Annisa Mahardiani Talitha Danendra Putri Tasya Mahira Salsabila Theresia Florida Damayanti Tri Wahyudi Tsabita, Irdandia Maitsa Tyrzaurra Amalya Maharani Umi Athiyah Umi Athiyah Via Qurrota A’yun Vidya Annisa Pebriastika Virly Natalia Virnanda Syafira Hartatiningrum Wahyuningtyas, Afifah Rahma Wahyuri Wahyuri Wardhani, Dewanti Wijaya, Aurellia Chance Wikanti Sunaringtyas Wiwin Dwi Rahmadani Tukloy Yuni Priyandani Yuniar Gusrianti Azzahra Za'im Hanif Al Fathoni Zahrani, Nafisah Zakiyya, Reyhana Rona