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All Journal PROSIDING SEMINAR NASIONAL Jurnal Kesehatan Andalas E-Dimas: Jurnal Pengabdian kepada Masyarakat HIGEIA (Journal of Public Health Research and Development) Majalah Kesehatan FKUB Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Medica Hospitalia Medica Arteriana (Med-Art) Science Midwifery Ahmad Dahlan Medical Journal Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika Mandala of Health : A Scientific Journal Jurnal Sosial dan Sains Innovative: Journal Of Social Science Research Ranah Research : Journal of Multidisciplinary Research and Development Prosiding Seminar Nasional Unimus
Yanuarita Tursinawati, Yanuarita
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Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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Efektivitas Ekstrak Daun Bidara (Ziziphus mauritiana) Terhadap Kadar Gula Darah pada Tikus Wistar yang Diinduksi Aloksan Putri, Zata Amani Fahdina; Rakhmawatie, Maya Dian; Tursinawati, Yanuarita
Prosiding Seminar Nasional Unimus Vol 7 (2024): Transformasi Teknologi Menuju Indonesia Sehat dan Pencapaian Sustainable Development G
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Pendahuluan: DM merupakan penyakit metabolik gangguan sistem endokrin yang bermanifestasihilangnya penyerapan karbohidrat. Beberapa penderita DM melakukan pengobatan tradisional salahsatunya daun Bidara. Daun Bidara memiliki flavonoid yang dijadikan sebagai salah satu metode pengobatanalternatif untuk mengendalikan kadar gula darah penderita DM. Flavonoid bekerja dengan cara hambatkerja enzim alfa-glukosidase sehingga kadar gula yang akan terserap oleh usus berkurang dan menurunkankadar gula darah. Tujuan penelitian ini yaitu mengetahui efektivitas dari ekstrak daun Bidara terhadap kadargula darah tikus Wistar yang telah diinduksi aloksan.Metode: Penelitian ini merupakan sebuah penelitian eksperimental metode true experimental dengan prepostcontrol group design. Pengambilan sampel dilakukan dengan panduan WHO terkait penggunaanhewan uji coba minimal 5 ekor tiap kelompok . Didapatkan 15 ekor tikus jantan galur Wistar sebagai sampelpenelitian, terbagi menjadi kelompok induksi aloksan dan ekstrak daun bidara 60 mg/200gbb (P1),kelompok metformin 9 mg/200gbb (P3), dan kelompok kombinasi (P3). Perbedaan kadar gula darahsebelum dan setelah perlakuan pada setiap kelompok diuji menggunakan jenis uji paired t-test.Hasil: Hasil uji analisis didapatkan bahwa waktu induksi aloksan optimal pada hari ke-3 penginduksiandan ekstrak daun bidara, metformin, serta kombinasi ekstrak daun bidara dan metformin memiliki efekdalam menurunkan kadar gula darah pada tikus yang telah diinduksi aloksan 20 mg/200gbb secarasignifikan pada hari ke-4 intervensi (p=0,035) dengan kelompok P3 yang paling signifikan (p=0,002).Kesimpulan: Ekstrak daun bidara dengan dosisi 60 mg/200 gbb memiliki efek penurunan kadar gula darahsecara signifikan pada tikus yang diinduksi aloksan dihari ke-4 intervensi. Kata Kunci : Ekstrak daun bidara, Metformin, Diabetes melitus, Aloksan, Kadar gula darah.
Hubungan Aktivitas Fisik dan Obesitas Sentral dengan Komplikasi Ulkus Diabetik Penderita DM Tipe 2 di Wilayah Puskesmas Rowosari II Sumayyah, Sumayyah; Wahab, Zulfachmi; Tursinawati, Yanuarita
Ranah Research : Journal of Multidisciplinary Research and Development Vol. 7 No. 3 (2025): Ranah Research : Journal Of Multidisciplinary Research and Development
Publisher : Dinasti Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/rrj.v7i3.1455

Abstract

Physical activity is any body movement caused by the work of skeletal muscles and increases the expenditure of energy and energy. Central obesity is the accumulation of excessive fat that can interfere with health. One of the chronic complications of diabetes mellitus, namely the problem of lesions on the feet called diabetik ulcers is a condition where open wounds are found on the skin surface on the feet in DM patients due to nerve abnormalities and peripheral arterial vascular disorders which can be caused by lack of physical activity and obesity. The purpose of this study was to analyze the relationship between physical activity and central obesity with the incidence of diabetik ulcer complications in type 2 DM patients. Analytical observational research with a case control approach. The research subjects were type 2 DM patients at the Rowosari II Health Center. The research instrument used was the GPAQ questionnaire to measure physical activity, midline to measure central obesity. Samples were taken according to the exclusion and inclusion criteria. In the bivariate analysis using the chi-square test with a significant value if p <0.05. Type 2 DM patients with mild moderate physical activity will have an OR = 22,8 (95% CI 2,7-193,7) of having diabetik ulcers than those with strenuous activity (p=0,005). Meanwhile, type 2 DM patients with central obesity will have an OR =11 (95% CI 0,59-47,3) having diabetik ulcers than type 2 DM patients who do not have central obesity(p=0,025). Light-moderate physical activity and the presence of central obesity have a significant relationship with the occurrence of diabetik ulcers in patients with type 2 diabetes.
Hubungan antara Kadar HbA1c dan Derajat Retinopati Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Mata Cicendo Bandung Farhani, Fathia; Wahab, Zulfachmi; Tursinawati, Yanuarita
Jurnal Kesehatan Andalas Vol. 12 No. 1 (2023): Online March 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v12i1.2157

Abstract

Diabetic retinopathy is the common complication of T2DM, which leads to vision loss. The severity of retinopathy can be affected by HbA1c levels. Controlling the glycemic such as HbA1c, may prevent the severity of diabetic retinopathy. Objective: To identified the association between HbA1c levels and severity of retinopathy in Type 2 DM patients at Cicendo Eye Hospital, Bandung. Methods: This research was an analytic observational study and cross-sectional approach. Samples were taken using purposive sampling and consisted of 70 people. The secondary data were from the outpatient's medical records at the Cicendo Eye Hospital in Bandung for the period September-October 2022. The Chi-square test was used for data analysis. Results: According to HbA1c levels, the uncontrolled HbA1C levels were found in 52 patients (74,3%) and the controlled were found in 18 patients (25,7%). Most of them were diagnosed with PDR were found 62% and the rest of it were diagnosed with NPDR. A significant association is found between HbA1c levels and the degree of diabetic retinopathy with p-value = 0.018 (p <0.05). Conclusion: HbA1c levels in Type 2 Diabetes Mellitus patients have a significant association with the severity of diabetic retinopathy, which can be used as a parameter for controlling diabetes complications, particularly retinopathy.Keywords: diabetic retinopathy, T2DM, HbA1c, glycemic control
PENGARUH EFEK EKSTRAK ETANOL DAUN BAYAM HIJAU (Amaranthus hybridus L.) TERHADAP MOTILITAS SPERMATOZOA: Studi Pada Tikus Wistar Jantan Dengan Paparan Asap Rokok Mulyani, Diah Nauvalia; Hediningsih, Yekti; Tursinawati, Yanuarita
Mandala Of Health Vol 17 No 2 (2024): Mandala of Health: a Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2024.17.2.11828

Abstract

Cigarette smoke contains free radicals that trigger oxidative stress causing decreased sperm motility. A decrease in antioxidants causes reduced motility. Antioxidants found in vegetables in green spinach leaf extract function as antioxidants to prevent oxidant stress and increase levels of Reactive Oxygen Species (ROS). The aim of this study was to determine the effect of ethanol extract of green spinach leaves (Amaranthus hybridus L.) on spermatozoa motility. This quasi-experimental research used 25 male Rattus norvegicus mice using a post-test only control group design strategy and a simple random sampling approach. The initial stage in data analysis is the normality test. The Levene One Way ANOVA test was then performed, and the Post Hoc LSD test was used to compare the results. Based on the research results, the ethanol extract group of green spinach leaves had maximum motility at a dose of 588 mg/KgBW (82%) and the lowest at a dose of 147 mg/KgBW (64%). The groups Kn- and Kn+ (0.000), Kn- and P1 (0.000), Kn+ and P2 (0.009), Kn+ and P3 (0.005), P1 and P2 (0.009), and P1 and P3 (0.005) are significantly different from each other. Ethanol extract of green spinach leaves (Amaranthus hybridus L.) affected spermatozoa motility, and significant differences were seen among the five groups studied.
Relationship between physical activity and sedentary lifestyle with the incidence of obesity in bri bank malang kawi employees Aini, Hasna Nabiilah Nur; Tursinawati, Yanuarita; Kurniati, Ika Dyah
Science Midwifery Vol 13 No 4 (2025): October: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2062

Abstract

Lack of physical activity and sedentary lifestyle habits can lead to obesity. Insufficient physical activity may result in decreased energy expenditure in the body, creating an imbalance between energy intake and output during daily activities. This study aimed to analyze the relationship between physical activity and sedentary lifestyle with obesity among employees of BRI Malang Kawi Bank. This research employed an analytical observational design with a case-control approach. Samples were selected using purposive sampling, consisting of 15 obese and 15 non-obese respondents. Physical activity data were collected using the GPAQ questionnaire, while sedentary lifestyle was assessed using the WSQ questionnaire, both completed by the employees in December 2023. Spearman rank correlation analysis was used. Most respondents had sufficient physical activity, with 60% in the obese group and 80% in the non-obese group. Weekend sedentary time was 7.1 hours for obese and 8.9 hours for non-obese respondents. A significant positive correlation was found between physical activity and obesity (p = 0.037), whereas no significant relationship was observed between sedentary lifestyle and obesity (p = 0.952). Physical activity significantly influenced obesity incidence, while sedentary lifestyle had no effect among BRI Malang Kawi Bank employees.
Analisis Pengaruh Pemberiaan Ektrak Rimpang Jahe (Zingiber Officinale Rosc.) terhadap Gambaran histolopatologi islet panckreas Pada Tikus wistar Model Hiperglikemia: Sebuah Studi Preklinis Setiawan, Bela Bagus; Tursinawati, Yanuarita; Widianingrum, Rifka
Jurnal sosial dan sains Vol. 5 No. 9 (2025): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jurnalsosains.v5i9.32500

Abstract

Diabetes mellitus (DM) is a metabolic disease with increasing prevalence in Indonesia. Melatonin is known to have promising antioxidant and antidiabetic properties. Ginger (Zingiber officinale Rosc.) contains higher melatonin content compared to other spices. To identify the effect of melatonin-rich ginger rhizome extract on blood glucose levels in hyperglycemic rats induced by STZ-NA. True experimental study with Pre Test Post Test Control Group Design using 30 male Wistar strain rats divided into 5 groups: negative control (K-), positive control (K+), ginger extract 100 mg treatment (P1), ginger extract 200 mg treatment (P2), and metformin positive control (P3). Hyperglycemia was induced with STZ-NA, then treated for 21 days. Blood glucose levels were measured using GOD-PAP method. There were significant differences in islet of Langerhans histopathology between groups (p=0.001). The K(-) group showed normal conditions (mean Allred: 4.6), while K(+) experienced severe necrosis (mean Allred: 2.32). The P2 group showed the best improvement (mean Allred: 4.8), followed by P3 (3.9) and P1 (3.72). Melatonin-rich ginger rhizome extract has protective effects against islet of Langerhans histopathological damage in hyperglycemic rat models, with 200 mg dose showing the best effectiveness.
Relationship Between The Amount Of Protein Intake And The Weight Gain Of Pregnant Women During Pregnancy With Low Birth Weight Babies Widiasih, Esti; Nadila, Nadila; Tursinawati, Yanuarita
Ahmad Dahlan Medical Journal Vol. 6 No. 2 (2025): November 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/admj.v6i2.10878

Abstract

Protein intake is the main determinant in the survival, growth and development of the embryo while weight gain during pregnancy is needed to support the development and growth of the fetus in the womb. Birth weight is also related to the fulfillment of nutrition during pregnancy, where the fulfillment of maternal nutrition can be measured through its anthropometry, namely weight gain during pregnancy. This study aims to prove the relationship between the amount of protein intake and the weight gain of pregnant women during pregnancy with the baby's birth weight. This research method was analytic observational with a case control design. The research subjects were mothers who had babies with normal and low birth weight who met the inclusion and exclusion criteria. The sampling technique was purposive sampling. The research instrument was using the SQ-FFQ questionnaire about protein intake with interviews by nutritionist enumerators. Statistical test was using Chi-square correlation. A total of 32 research subjects, the majority aged 20-35 years (81.2%), moderated educational status (62.5%), low economic status (50%), parity was not at risked (84.4%), weight gain was appropriated ( 56.3%) and low protein intake (53.1%). The chi-square test obtained a p value of 0.013 and a p value of 0.021, which means that there was a relationship between the amount of protein intake and the weight gain of pregnant women during pregnancy with the birth weight of the baby.
SKRINING FUNGSI KOGNITIF DAN KADAR ASAM URAT PADA PESERTA PROLANIS KLINIK DOKTER KELUARGA Purwoko, Mitayani; Heriyanto, Mochammad Junaidy; Sulistiyani, Sulistiyani; Sriningsih, Solikah; Putra, Chendra Perdana; Gani, Rima January Putri Ridwan; Prakoso, Denny Anggoro; Novitasari, Erlina Krisdianita; Tubarad, Gladys Dwiani Tinovella; Sukarno, Rizky Triutami; Rudiyanto, Waluyo; Pandhita, Gea; Aziza, Nurita; Tursinawati, Yanuarita; Airlangga, Muhammad Perdana; Setiawan, Meddy; Romi, M. Mansyur
Jurnal Pengabdian Masyarakat Medika Vol 5. No. 2, September 2025
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jpmmedika.v5i2.12547

Abstract

ABSTRAK Fungsi kognitif dan kadar asam urat darah lansia tidak termasuk dalam pemeriksaan wajib dalam program Prolanis. Fungsi kognitif perlu dinilai untuk memastikan bahwa peserta Prolanis tidak mengalami kemunduran fungsi kognitif. Tujuan kegiatan ini adalah untuk melakukan skrining tingkat fungsi kognitif dan kadar asam urat darah peserta Prolanis di Klinik Dokter Keluarga Fakultas Kedokteran Universitas Muhammadiyah Palembang. Kegiatan dilaksanakan dalam satu hari selama 2 jam 30 menit. Pemeriksaan fungsi kognitif dilakukan menggunakan kuesioner Mini Mental State Examination (MMSE) berbahasa Indonesia. Pemeriksaan kadar asam urat darah dilakukan menggunakan darah dari ujung jari dengan alat pemeriksa asam urat dan strip khusus. Hasil skrining menunjukkan bahwa 80,4% peserta Prolanis memiliki fungsi kognitif yang normal dan 66,7% memiliki kadar asam urat darah yang normal.   ABSTRACT Cognitive function and blood uric acid levels in the elderly are not included in the mandatory screening in the Prolanis program. Cognitive function needs to be assessed to ensure that Prolanis participants do not experience cognitive decline. The purpose of this activity was to screen the cognitive function and blood uric acid levels of Prolanis participants at the Family Physician Clinic, Faculty of Medicine, Muhammadiyah University of Palembang. The activity was carried out in one day for 2 hours and 30 minutes. Cognitive function testing was conducted using the Indonesian language Mini Mental State Examination (MMSE) questionnaire. Blood uric acid testing was performed using fingertip blood with a uric acid tester and special strips. The screening results showed that 80.4% of Prolanis participants had normal cognitive function and 66.7% had normal blood uric acid levels.
PENGARUH PEMBERIAN EKSTRAK KAYA MELATONIN RIMPANG JAHE EMPRIT (ZINGIBER OFFICINALE VAR.AMARUM) TERHADAP KADAR GULA DARAH TIKUS JANTAN GALUR WISTAR HIPERGLIKEMIA Rahmatullah, Dyfan Elian; Tursinawati, Yanuarita; Kurniati, Ika Dyah
Prosiding University Research Colloquium Proceeding of The 19th University Research Colloquium 2024: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

"ABSTRAK Latar Belakang :Keadaan hiperglikemia pada DMs meningkatkan konsentrasi radikal bebas dalam tubuh sehingga menyebabkan kerusakan sel ? pankreas. Kerusakan dapat dibatasi dengan jahe emprit sebagai antidiabetik dan tinggi melatonin. Aktivitas inhibisi enzim ?-glukosidase jahe emprit lebih kuat dibanding jahe lainnya. Penelitian bertujuan menganalisis pengaruh pemberian ekstrak kaya melatonin jahe emprit terhadap kadar gula darah tikus hiperglikemia yang diinduksi Streptozotosin Nikotinamid (STZ-NA). Metode: Rancangan penelitian adalah Pre Test Post Test Control Group Design. Sampel penelitian tikus putih jantan galur wistar berjumlah 30 ekor dibagi menjadi 5 kelompok. Kelompok tersebut adalah tidak diinduksi STZ-NA (K-), diinduksi STZ-NA(K+), diinduksi STZ-NA diberi ekstrak Jahe 100 mg/ kg BB/hari (P1), diinduksi STZ-NA diberi ekstrak Jahe 200 mg/kg BB/hari (P2), diinduksi STZ-NA diberi metformin 300 mg/ kg BB/hari (P3). Perlakuan selama 21 hari. Kadar gula darah sewaktu diukur sebelum dan sesudah perlakuan. Untuk mengetahui perbedaan kadar gula darah digunakan uji paired t dan one way anova. Hasil : Kadar gula darah tikus sebelum perlakuan terendah adalah K-: 109,4 mg/dl dan tertinggi adalah P2: 426,8 mg/dl . Kadar gula darah tikus sesudah perlakuan terendah K-: 110,8 mg/dl dan tertinggi adalah K+: 399,2 mg/dl. Penurunan kadar gula darah terbesar terjadi pada P3 yaitu 262,8 mg/dl. Ada perbedaan bermakna penurunan kadar gula antara K- dengan P1, K- dengan P2, K- dengan P3, K+ dengan P1, K+ dengan P2 serta K+ dengan P3. Kesimpulan : Ekstrak kaya melatonin rimpang jahe emprit dapat menurunkan kadar GDS tikus yang di induksi STZ-NA. "
The Relationship Between Stress Levels And The Incidence Of Hair Loss (Telogen Effluvium) In Beginning And Final Level Students Of Unimus Faculty Of Medicine Kartika Sari, Sophie isfa; Indrastiti, Retno; Tursinawati, Yanuarita
Innovative: Journal Of Social Science Research Vol. 4 No. 2 (2024): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v4i2.10151

Abstract

Telogen effluvium adalah salah satu bentuk kerontokan rambut kulit kepala yang paling umum. Telogen effluvium ditandai dengan kerontokan rambut yang menyebar, dimana rambut telogen melebihi batas normal kerontokan rambut dalam sehari, yaitu lebih dari 80-100 helai. Salah satu penyebab paling umum dari gangguan kerontokan rambut (Telogen Effluvium) adalah stres. Mahasiswa kedokteran merupakan salah satu kelompok masyarakat yang berisiko mengalami stres akibat aktivitas pendidikan yang dialaminya. Tugas perkuliahan, praktikum, ujian, dan proses adaptasi dengan lingkungan belajar di kampus merupakan stressor bagi mahasiswa kedokteran. Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross sectional. Populasi penelitian adalah seluruh mahasiswa angkatan 2018 dan 2021. Sampel penelitian dibagi menjadi dua yaitu kelompok yang mengalami kerontokan rambut dan kelompok tidak mengalami kerontokan rambut yang masing-masing berjumlah 35 sampel. Pengumpulan data menggunakan kuesioner. Analisis data menggunakan uji univariat dan bivariat dengan uji Odd Ratio. Mahasiswa tingkat akhir yang mengalami stres sedang hingga berat OR = 2.67 (95% CI 1.3-3.7) mengalami kerontokan rambut dibandingkan mahasiswa tingkat akhir yang memiliki tingkat stres ringan. Sedangkan siswa tingkat awal yang memiliki tingkat stres sedang-berat akan memiliki OR = 1,3 (95% CI 1,2-4,6) mengalami kerontokan rambut dibandingkan siswa tingkat awal yang memiliki tingkat stres ringan.
Co-Authors Adelina, Annastania Adnan, Malik Hisyam Aini, Hasna Nabiilah Nur Ardana Putri, Izza Alya Atmaja, Tajudin Rahmat Surya Aziza, Nurita Bela Bagus Setiawan Bilqis, Maziyyah Mona DG, Adinda Trimegasiwi Farhani, Fathia Fauzia, Ana Fuad, Wijayanti Fuad, Wijayanti Habib, Ahmad Yusuf Hediningsih, Yekti Heriyanto, Mochammad Junaidy Hukma Adila, Laila Arina Humaistina, M Hilda Farid Ika Dyah Kurniati Ika R, Risky Indrastiti, Retno Juliani, Aliyah Ari Kanti Ratnaningrum Kartika Sari, Sophie isfa Kartikadewi, Arum Kasattu, Bhre Dharnaratti Leksani, Anggita Pungki Lestari, Ary Diah M. Mansyur Romi Maya Dian Rakhmawatie Meddy Setiawan Mitayani Purwoko, Mitayani Muhammad Perdana Airlangga, Muhammad Perdana Mulyani, Diah Nauvalia Muslimah Nadila, Nadila Nasrullah, Bintang Tatius Novitasari, Erlina Krisdianita Nugraheni, Dyah Mustika Nurhayati, Intan Nurina Dyah Larasaty, Nurina Dyah Pandhita, Gea Prakoso, Denny Anggoro Putra, Chendra Perdana Putri, Zata Amani Fahdina Rahmatullah, Dyfan Elian Ramadhani, Nuzul Zakila Reza Nisrina Salzabella Riani, Risky Ika Rima January Rudiyanto, Waluyo Sabina, Ardelia Setiowati, Lilis Sriningsih, Solikah Sukarno, Rizky Triutami SULISTIYANI SULISTIYANI Sumayyah Sumayyah, Sumayyah Swasty, Swasty Tubarad, Gladys Dwiani Tinovella Wahab, Zulfachmi Widianingrum, Rifka Widiasih, Esti Yudhistira, M Abrian