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All Journal MPI (Media Pharmaceutica Indonesiana) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Ilmiah Manuntung JCPS (Journal of Current Pharmaceutical Sciences) JURNAL FARMASIMED (JFM) Jurnal Pengabdian Al-Ikhlas Jurnal Pengabdian Kepada Masyarakat (Mediteg) Jurnal Jejaring Matematika dan Sains Borneo Journal Of Pharmascientech Jurnal Insan Farmasi Indonesia Tropical Health and Medical Research Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal AFAMEDIS Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Bakti Untuk Negeri Benzena Pharmaceutical Scientific Journal Jurnal Pengabdian Masyarakat Panacea Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Anna Khumaira Sari
Universitas Lambung Mangkurat
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary

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Antioxidant Activity and Marker Compound Levels of Cempedak Leaf (Artocarpus integer) Extract in Different Solvent Variations Sari, Anna Khumaira; Rizki, Muhammad Ikhwan; Azhara, Desiya Damayanti; Fadlilaturrahmah, Fadlilaturrahmah
Tropical Health and Medical Research Vol. 6 No. 2 (2024): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v6i2.123

Abstract

Cempedak (Artocarpus integer) is known to contain phenolic compounds. Phenolic compounds are secondary metabolites of plants included in marker compounds that act as natural antioxidants because they have hydroxyl groups that can reduce free radicals. Plants containing phenolic compounds are known to have strong antioxidant activity. This study aimed to determine the antioxidant activity and levels of marker compounds from ethanol extracts of cempedak leaves in various solvent variations. Cempedak leaves were dried in an oven and then powdered. Cempedak leaf powder was extracted using methanol, 70% ethanol, 96% ethanol using the maceration method, and distilled water was extracted using the boiling method. The extract was tested for antioxidant activity using the DPPH (1,1-diphenyl-2-picryl-hydrazyl) method based on the IC50 value. Determination of marker compound levels using the Folin-Ciocalteu reagent with a gallic acid comparator using a UV-Vis spectrometer instrument. The total phenolic content determination test results were expressed as gallic acid equivalents per gram of extract (GAE/g extract). The results of the antioxidant activity test showed the IC50 value of the methanol extract was 84.48 ppm (strong), the distilled water extract was 54.74 ppm (strong), the 70% ethanol extract was 72.21 ppm (strong), and the 96% ethanol extract was 24.55 ppm (very strong). The results of the marker compound determination showed the total phenolic content of the methanol extract was 28.22% w/w, the distilled water extract was 22.59% w/w, the 70% ethanol extract was 29.55%, and the 96% ethanol extract was 31.14% w/w. It can be concluded that the cempedak leaf extract extracted with 96% ethanol has very strong antioxidant properties and the highest marker compound content among other solvents. For further analysis, 96% ethanol solvent can be used for the cempedak leaf extraction.
PENGARUH BRIEF COUNSELING FARMASIS TERHADAP AKTIVITAS FISIK DAN HASIL TERAPI PASIEN HIPERTENSI RAWAT JALAN DI POLIKLINIK PENYAKIT DALAM RSUD ULIN BANJARMASIN Saftia Aryzki; Noverda Ayuchecaria; Anna Khumaira Sari
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i1.206

Abstract

According to Riskesdas (2013) the prevalence of hypertension in South Kalimantan Province is 30.4%, this means around 1,145,536 people. Risk factors are occupation of less physical activity 26.1% and residents> 10 years consuming less vegetables and fruits. The government invites the entire community to carry out a movement of healthy living people by doing physical activities, consuming vegetables and fruits and checking health regularly. The purpose of this study was to determine the effect of Brief Counseling of Pharmacists on Physical Activity and Therapeutic Results of Hypertensive Patients Outpatient in the Internal Medicine Polyclinic of Ulin Hospital, Banjarmasin.The quasi-experimental study used a prospective two-group pretest and posttest design. Patients were grouped randomly into two groups, namely the group that received the intervention in the form of a pharmacist / researcher briefing and group without intervention (control) followed for one month. Sampling using co-executive sampling method that meets the inclusion and exclusion criteria. The study was conducted at the internal medicine clinic at Ulin Banjarmasin Public Hospital in the period January-March 2018. The instrument used is International Physical Activity Questionnaire (IPAQ).The results of physical activity data analysis in the control group with the Wilcoxon Test which showed data had a significant difference (p <0.05), while in the treatment group with the Wilcoxon Test which showed data did not have a significant difference (p> 0.05). Analysis of blood pressure data in the control group with the Wilcoxon Test which showed data had a significant difference (p <0.05), while in the treatment group with the Wilcoxon Test which showed data had a significant difference (p <0.05).
Pemberdayaan Kader dalam Upaya Deteksi Dini Penyakit Tidak Menular (PTM) sebagai Upaya Preventif dan Optimalisasi Kegiatan Posyandu di Puskesmas Landasan Ulin Fitriana, Mia; Sari, Anna Khumaira; Intannia, Difa; Rahmatullah, Satrio Wibowo; Sandi, Dita Ayulia Dwi; Wasiaturrahmah, Yusrinie; Muslimawati, Khoirunnisa; Isnaini, Nazhifah
Jurnal Pengabdian Masyarakat Panacea Vol 2, No 4 (2024): Jurnal Pengabdian Masyarakat Panacea
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpmp.v2i4.14140

Abstract

Penyakit Tidak menular (PTM) menjadi permasalahan global yang membutuhkan perhatian serius, karena menyebabkan kasus kematian terbanyak di dunia (74%). Pelayanan kesehatan dasar  pada Penyakit Tidak Menular (PTM) di Puskesmas Landasan Ulin masih ada yang belum mencapai target yang diharapkan, Kegiatan pengabdian masyarakat ini bertujuan untuk melakukan pemberdayaan kader posyandu di wilayah Puskesmas Landasan Ulin melalui pembuatan paket edukasi dan sosialisasi tentang PTM, melakukan deteksi dini dan upaya promosi kesehatan terkait PTM kepada masyarakat. Kegiatan meliputi sosialisasi kepada kader dan peserta posyandu, pelatihan dan penerapan teknologi dilakukan kepada kader posyandu tentang penggunaan alat cek kadar glukosa, kolesterol dan asam urat yang digunakan untuk deteksi dini PTM serta interpretasi dari hasil tes yang diperoleh kemudian dievaluasi dengan hasil pretest dan postest. Berdasarkan hasil evaluasi, terjadi peningkatan skor rata-rata dari kader dan peserta. Hasil skor rata-rata kader posyandu saat pretest sebesar 7,88 meningkat menjadi 8,6 pada skor rata-rata postest, sedangkan hasil skor rata-rata peserta posyandu saat pretest sebesar 7,2 meningkat menjadi 7,9 pada skor rata-rata postest. Peningkatan yang terjadi tidak terlalu signifikan (8 % untuk kader dan 7 % untuk peserta), hal ini mungkin dikarenakan pengetahuan dasar baik kader maupun peserta sudah cukup baik sebelum diberikan sosialisasi. Kata Kunci: Hipertensi, Diabetes Miletus, Faktor Resiko, Pelatihan  Non-communicable diseases (NCDs) are a global problem that requires serious attention. This NCDs has become the cause of most deaths in the world, namely 74%. Landasan Ulin Community Health Center has a population of 77,982 people. In basic health services for Non-Communicable Diseases (NCDs), there are still some that have not reached the expected target. This community service activity aims to empower posyandu cadres in the Landasan Ulin Community Health Center area through creating educational packages and outreach about NCDs, carrying out early detection and efforts health promotion related to NCDs to the community. Activities include outreach to posyandu cadres and participants, training and application of technology to posyandu cadres regarding the use of tools to check glucose, cholesterol and uric acid levels which are used for early detection of NCDs as well as interpretation of the test results obtained which are then evaluated with pretest and posttest results. Based on the evaluation results, there was an increase in the average score of cadres and participants. The average score of posyandu cadres during the pretest was 7.88, increasing to 8.6 in the average score of the posttest, while the average score of posyandu participants during the pretest was 7.2, increasing to 7.9 in the average score of the posttest. The increase that occurred was not very significant (8% for cadres and 7% for participants), this may be because the basic knowledge of both cadres and participants was quite good before being given socialization and education.
Kacip Fatimah (Labisia pumila) as Natural Sunscreen: Analysis of Flavonoid Content and Ultraviolet Protection Ability Rahmatullah, Satrio Wibowo; Rizki, Muhammad Ikhwan; Sari, Anna Khumaira; Sari, Fitri Novita; Fadlilaturrahmah, Fadlilaturrahmah; Junjung Buih, Putri Helena
Tropical Health and Medical Research Vol. 7 No. 1 (2025): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v7i1.132

Abstract

The cause of melanoma cancer is exposure to high-intensity ultraviolet rays from sunlight. Kacip Fatimah (Labisia pumila) utilizes the people of the interior of Kalimantan to protect their skin from sunlight by attaching leaves to the face or skin. Kacip Fatimah (Labisia pumila) contains flavonoid compounds, which are thought to impact these various properties. This study aimed to determine the ultraviolet protection ability and total flavonoid levels of Kacip Fatimah (Labisia pumila) leaves. Kacip Fatimah (Labisia pumila) leaves originating from Central Kalimantan were cleaned, dried in an oven, ground, and then extracted with air solvents, 70% ethanol, and 96% ethanol. Flavonoid identification was carried out with specific reagents, and total flavonoid levels were determined by colorimetric method using quercetin as a comparison. The ultraviolet protection ability of Kacip Fatimah (Labisia pumila) leaf extract was measured using a UV-Vis Spectrophotometer with the Sun Protection Factor parameter. The results showed the presence of flavonoids in the third extract. The total flavonoid content of air extract, ethanol 70%, and ethanol 96% from Kacip Fatimah (Labisia pumila) leaves were obtained respectively at 1.69%, 2.15%, and 2.38%. The most extracted flavonoids were in ethanol 96%solvent. The ultraviolet protection ability at a concentration of 100 - 500 ppm from air extract was in the range of 2.80 - 7.99, in ethanol 70% extract in the range of 5.69 - 38.39, while in ethanol 96% extract in the range of 8.76 - 49.07. The highest ultraviolet protection was in 96% ethanol extract from Kacip Fatimah (Labisia pumila) leaves. The results showed that Kacip Fatimah (Labisia pumila) leaves can provide ultraviolet protection with the content of active compounds of the flavonoid group. The research results can be scientific evidence for utilizing and developing products from Kacip Fatimah (Labisia pumila).
Co-Authors Ahmad Ahmad Ainun Mardiah Aisyah, Noor Akhsanul Rahmatullah Amalia Khairunnisa Amalia Khairunnisa, Amalia Amalia Khirunnisa Anisa Desriyanti Atikah Andria Saputri Ayu Soraya Ayuchecaria, Noverda Azhara, Desiya Damayanti Buih, Putri Helena Junjung Devi Eka Pratama Devia Pratiwi Dewi Kartika Dewi, Anita Ratna Difa Intannia Eka Kumalasari Elisya Fatmawati Erna Prihandiwati Erna Prihandiwati Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fadlillaturahmah Fadlillaturahmah Febrianti, Dwi Rizki Gina Alfandani Herningtyas Nautika Lingga Isnaini, Nazhifah Izma, Hayatun Jariyah Amilia Khairunnisa Khairunnisa Khoerul Anwar Khoirunnisa Muslimawati Liling Triyasmono Mahdjati Fitria Mawaddah Mawaddah Meilisa Eka Pratiwi Mia Fitriana Mochammad Maulidie Alfiannor Saputera muhammad fikri Muhammad Ikhwan Rizki Muhammad Rusydi Taufik Nazhipah Isnani Noor Cahaya Normaidah, Normaidah Normila Hayati Novia Ariani Nurul huda Prasdianto Prasdianto Rahma, Salsabila Fadiya RAHMANIAH RAHMANIAH Rahmatullah, Satrio Wibowo Rahmi Rahmi Rakhmadhan Niah Renny Renny Risma Ayati Riza Alfian Saftia Aryzki Saftia Aryzki Sandi, Dita Ayulia Dwi Sari, Fitri Novita Shela Puzi Dina Silviana, Mega Siska Musiam Syifa Auliani Syifa Auliani Vitalika Regitasari Wahyuni, Amaliyah Winsa Wira Wijaya Yusrinie Wasiaturrahmah