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Pengaruh Pemberian Probiotik pada Infeksi Clostridium Difficile Dharmawan, Ade; Agista, Dhimas Garin Dewa; Sinsanta, Sinsanta; Layanto, Nicolas; Deby, Deby
Jurnal MedScientiae Vol 1 No 2 (2022): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i2.2567

Abstract

Clostridium difficile (C. difficile) is a gram-positive, anaerobic, spore-forming bacterium, and is an important pathogen in antibiotic-associated diarrhea. These bacteria are normal flora in the human digestive tract but can become pathogenic and form toxins consisting of 2, namely toxin A and toxin B. Due to antibiotics including risk factors for C. difficile infection (CDI), the treatment that can be given is probiotics. Probiotics may be effective in the prevention and treatment of CDI in several ways: alteration of gut flora, enhancement of antimicrobial activity, and as immunomodulators. The effect of probiotics, the method of administration, and the varying duration of administration make probiotics unable to be used as a therapy for C. difficile infection. However, probiotics can still be an option for adjuvant therapy in the treatment of CDI.
Correlation Between Vulva Hygiene And Intrauterine Device Use And The Event Of Vaginal Discharge In Women Of Reproductive Age Damiani, Petri; Dharmawan, Ade; Layanto, Nicolas; Donna Mesina Rosadini Pasaribu
Jurnal MedScientiae Vol 2 No 3 (2023): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i3.2857

Abstract

Pathological leucorrhoea is an abnormal disorder in women of childbearing age that occurs in the body in the form of thick white, yellowish, greenish discharge. This is because the composition of the vaginal microflora fluctuates as a function of internal factors such as age,hormonal changes during menarche,menstruation,and pregnancy. External factors such as hygiene practices, sexual relations, and contraceptive use.In the use of Intrauterine devices, there is vaginal discharge that occurs as a result of the initial reaction to the presence of a foreign body, the use of intrauterine contraceptives which can change the chemical balance of the vagina and is thought to cause vaginitis. The research method for this literature review analyzed 8 research articles and assessed the articles based on predetermined inclusion and exclusion criteria. This literature reviews various risk factors that influence the occurrence of vaginitis due to the use of non-hormonal intrauterine contraceptive devices that occur in women of childbearing age and through good vulva hygiene behavior,can reduce the risk of physiological and pathological vaginal discharge.Based on these sources,it can be concluded that there is a relationship between vulva hygiene and the use of Intrauterine device with the incidence of vaginal discharge in women of childbearing age.
Efektivitas Antibakteri Ekstrak Daun Sirih Hijau (Piper betle (L)) pada Escherichia coli dengan Metode Dilusi : Efektivitas Antibakteri terhadap Escherichia coli dengan Metode Dilusi Malo, Mikhael Angelo; Dharmawan, Ade; Pasaribu, Donna Mesina Rosadini
Jurnal MedScientiae Vol 5 No 2 (2026): August
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v5i2.4387

Abstract

Escherichia coli bacteria is one of the bacteria that can cause health problems for humans, including in Indonesia. This encourages the need for ways to deal with health problems. Indonesian people have been familiar with the tradition of medicine using plants around the community such as green betel leaves (Piper betle (L)). Betel leaves contain many compounds that can work as antibacterials, so they can be used to overcome problems caused by Escherichia coli bacteria. The purpose of this study was to extract green betel leaves (Piper betle (L)), the compound content in the extract was used to determine the antibacterial ability against Escherichia coli bacteria. The method in this study was to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) by tube dilution. The results of the study The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) produced at a percentage of 2%. The study concluded that green betel leaf extract (Piper betle (L)) has the ability as an antibacterial against Escherichia coli bacteria.
Co-Authors Agista, Dhimas Garin Dewa Agus Cahyadi Amany, Hana Amirah Andini, KD Ayu Asti Anis Karuniawati Antoni, Marcel Cahyadi, Agus Christopher, Jeremy Clara Valentia Josephine Cleopas Martin Rumende Damiani, Petri Deby Deby Deby Deby Delly Chipta Lestari Devita, Arleen Dhimas Garin Dewa Agista Diana Wijaya Dominica Pita Sari Donna Mesina Pasaribu Donna Mesina Pasaribu Donna Mesina Rosadini Pasaribu Donna Mesina Rosadini Pasaribu Elena, Irene Maria Elisabeth D Harahap Elisabeth Harahap Farsida, Farsida Gratia Erlinda Tomasoa Guntur Darmawan Harahap, Elisabeth Henny Tannady Tan Henny Tannady Tan Heri Setiyo Bekti Husna, Ismalia Indriyani Indriyani Istia, Mieke Joseba Jeremy Christopher Kosasih, Audia Nizhma Nabila Krisna Fernanda Suryaputra Lasma Susi F. Simanjuntak Layanto, Nicolas Layanto, Nicolas Malo, Mikhael Angelo Marcel Antoni Mardhia Mardhia Marpaung, Nurasi Lidya E. Marshell Tendean Monica Cherlady Anastasia Monica Cherlady Anastasia Nicolas Layanto Nicolas Layanto Nicolas Layanto Nicolas Layanto Nicolas Layanto Nicolas Layanto Nicolas Layanto Nicolas Layanto Nicolas Layanto Pasaribu, Donna Mesina Petri Damiani Anindyajati Petri Damiani Anindyajati Pratiwi Pujilestari Sudarmono Rike Syahniar Rina, Veronica Rini Latifah Septiana, Yorisye Simanjuntak, Lasma Susi F. Sinsanta Sinsanta Sinsanta Sinsanta Suparto Suparto Suparto Suparto Tamara Atmogo Theresia Ervina Wahid Haikal Wani D Gunardi Wani Devita Gunardi Wani Devita Gunardi Widya Widya Wijaya, Jefri Wijaya, Pande I Gede Indra William Dharma Wijaya William William