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DEVELOPMENT SCORING SYSTEM TO PREDICT IN-HOSPITAL MORTALITY IN STROKE PATIENTS IN INDONESIA Rahmalia Izzati, Fatma; Arisetijono, Eko; Rahmawati, Dessika; Hariyanti, Tita
MNJ (Malang Neurology Journal) Vol. 12 No. 2 (2026): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2026.012.02.04

Abstract

Background: Stroke is the third leading cause of death globally, and early prediction of in-hospital mortality risk is essential for improving clinical outcomes and optimizing resource allocation. However, no in-hospital mortality system applicable to both ischemic and hemorrhagic stroke currently exists in Indonesia. This study aims to identify significant predictors of in-hospital mortality among stroke patients, to develop an in-hospital mortality prediction score system, and to assess the performance of the score. Methods: This retrospective cohort study included stroke patients hospitalized at Dr. Saiful Anwar Hospital, Malang, Indonesia in January-December 2024, with data obtained from electronic medical records. Multivariate logistic regression with backward stepwise elimination was performed to identify predictors significantly associated with in-hospital mortality. Scoring weights were derived from regression coefficients. Model performance was assessed using accuracy, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and the area under the curve (AUC). Results: Eight significant predictors were identified: age ≥60 years, male sex, National Institute of Health Stroke Scale (NIHSS) ≥16, leukocytosis, hyperglycemia, hemorrhagic stroke type, pneumonia, and sepsis. These predictors were incorporated into an in-hospital mortality scoring system. The scoring system demonstrated an accuracy of 72.92%, sensitivity 80%, specificity 71.77%, PPV 31.37%, NPV 95.7%, and an AUC of 0.784. Conclusions: Eight out of thirteen proposed predictors were significantly associated with in-hospital mortality among stroke patients. Based on these predictors, a prognostic scoring system for in-hospital mortality was developed, demonstrating fair discriminative performance.
STROKE PREVENTION EDUCATION AND POST-STROKE CARE, AND EXPLORATION OF GENETIC PROFILES Arisetijono, Eko; Yueniwati, Yuyun; Setianto , Catur Ari; Prabowo , Bisma Dewanto Ari; Ernanda , Shelby Amrus; Agustin , Aisyiyah Alviana; Gumelar , Enggar; Hasibuan , Muhammad Effendy Nugraha; Irnanda , Miranthi Ayu; Azzakiy , Ahmad Abdul Hadiy; Riandono , Dody; Ibrahim , Ananto Suar Bhakti; Pratama , Senoadji; Friscillia , Febrina; Muhammad , Galang Mahasin; Aprilianingtyas , Arvidareyna Panca; Putri , Firda Aunidiah; Rahmaditta , Allyssa; Purnama , Sari Dianita; Maliga , Helnida Anggun
MNJ (Malang Neurology Journal) Vol. 12 No. 2 (2026): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2026.012.02.06

Abstract

Background: Stroke is a leading cause of disability and mortality in Indonesia, making prevention and post-stroke care crucial to improving patients' quality of life. Objective: This community service project aimed to provide education on stroke prevention and post-stroke care in Besole Village, introduce a stroke risk screening application called Sinarsis (https://sinarsis.id), and explore genetic risk profiles for stroke in one participant. Methods: The method employed was a classical educational approach, encompassing explanations of stroke, prevention strategies, and post-stroke care by family members. Participants were also introduced to the Sinarsis application as a stroke risk screening tool. Results: Out of 51 participants, evaluation results indicated that 80% rated the program as highly beneficial, while 20% found it beneficial. Additionally, 90% of participants strongly agreed that similar programs should be conducted in the future. Regarding perceived knowledge gain, 86% of participants reported acquiring new insights on stroke, and 90% reported feeling highly motivated to prevent stroke. Furthermore, 84% of participants with family members who had experienced a stroke reported feeling highly motivated to improve post-stroke care. A genetic risk profile examination was conducted on one participant for further exploration of stroke risk, though it was limited to a single individual due to constraints on testing kits and funding. Conclusion: In conclusion, this educational program effectively enhanced knowledge and motivation among Besole Village residents regarding stroke prevention and post-stroke care. The Sinarsis application is anticipated to serve as a valuable tool for community-based stroke risk screening.
IMPROVING FAMILY RESILIENCE IN PRIMARY AND SECONDARY STROKE PREVENTION THROUGH LIFE'S ESSENTIAL 8-BASED INTERVENTION Arisetijono, Eko; Yueniwati, Yuyun; Damayanti, Ria; Ernanda, Shelby Amrus; Savitri, Kania Aviandi; Romadhoni, Muhammad Rifqy; Taqiyyah, Masyalia Hasna; Haq, Nabiila Ala Qoonita Najma; Sinaga, Alexandra Maria Rossadwina Sriharkita; Alam, Satria Sabda; Zahra, Farah Shabri Alifia; Pranowo, Muhammad Royyan; Raihana, Naura Salwa; Siraj, Resnanda Naufal
MNJ (Malang Neurology Journal) Vol. 12 No. 2 (2026): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2026.012.02.24

Abstract

Background: Stroke is a leading cause of long-term disability in Indonesia, with rising incidence among individuals of productive age. Rural communities face multiple challenges, including low health literacy, high prevalence of risk factors, and persistent misconceptions about stroke prevention and post-stroke care. Objective: This study aimed to evaluate the effectiveness of a community-based intervention using the Life’s Essential 8 (LE8) framework and the SIGAP 8 pocket-book to strengthen family preparedness for primary and secondary stroke prevention in Besole Village, Tulungagung. Methods: A mixed-methods approach was applied in two phases: (1) pre-intervention assessment through demographic surveys, in-depth interviews, and FGDs with stakeholders to identify community needs; and (2) intervention through structured education, health screening, and pre–post knowledge testing. Participants underwent measurements of blood pressure, BMI, glucose, cholesterol, WHO stroke risk assessment, and Barthel Index evaluation for survivors. User experience of the SIGAP 8 booklet was assessed using the User Experience Questionnaire (UEQ). Results: A total of 34 stroke survivors and 21 non-stroke participants were included. Among survivors, 58.8 percent had stage 2 hypertension and 26.5 percent had glucose ≥200 mg/dL. Most demonstrated moderate dependence on the Barthel Index. Among non-stroke participants, 57.1 percent were classified as moderate risk. UEQ scores indicated positive user experience across dimensions, including dependability (3.82), attractiveness (3.69), and clarity (3.67). The LE8-based intervention effectively improved health literacy, motivation, and family capacity in monitoring stroke risk factors. Conclusion: The SIGAP 8 pocket-book was well-received and shows strong potential as a community-level tool for stroke prevention in rural areas.
CLINICAL PROFILE OF STROKE SEVERITY BASED ON NIHSS, MORTALITY, AND PNEUMONIA INCIDENCE AMONG FEMALE STROKE PATIENTS Arisetijono, Eko; Putri, Adecya Amaryllis Risa; Andarini, Sri; Agustin, Aisyiyah Alviana
MNJ (Malang Neurology Journal) Vol. 12 No. 2 (2026): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2026.012.02.07

Abstract

Background: Stroke is a leading cause of mortality and long-term disability worldwide, with women exhibiting distinct clinical characteristics and generally poorer outcomes than men. Female-specific risk factors, older age at onset, and greater stroke severity contribute to unfavorable prognoses. As a tertiary referral center in East Java, Dr. Saiful Anwar General Hospital treats a large number of female stroke patients, yet comprehensive clinical data remain limited. Objective: To describe the clinical profile of female stroke patients, focusing on stroke severity based on NIHSS scores, mortality, and pneumonia incidence. Methods: This retrospective descriptive study included 202 female stroke patients admitted between January and December 2024. Data were extracted from electronic medical records. Results: Most patients were aged 45–64 years (46.5%) or ≥65 years (44.6%), and the majority were housewives (80.2%). Thrombotic stroke predominated (55.4%) over intracerebral hemorrhage (44.6%). Hypertension was the most prevalent vascular risk factor (96.0%), followed by diabetes mellitus (42.1%), dyslipidemia (35.1%) and heart disease (32.2%). Stroke severity was predominantly moderate to very severe, with 91.1% of patients presenting with NIHSS scores ≥5. Pneumonia was the most frequent complication (51.5%). Overall mortality reached 45.0%. Conclusion: Female stroke patients demonstrated a high burden of vascular risk factors, severe neurological impairment, frequent complications, and mortality far exceeding global averages. These findings highlight the urgent need for strengthened prevention strategies, improved acute stroke care, early complication management, and targeted interventions for this vulnerable population.
Co-Authors Agustin , Aisyiyah Alviana Agustin, Aisyiyah Alviana Alam, Satria Sabda Aprilianingtyas , Arvidareyna Panca Arief Andy Soebroto Asmiragani, Syaifullah Azzakiy , Ahmad Abdul Hadiy Badrul Munir, Badrul Catur Ari Setianto Catur Ari Setianto, Catur Ari Chozin, Iin Noor Damayanti, Ria Deby Putri Indraswari Dessika Rahmawati Didi Candradikusuma Dwi, Pratiwi Suryanti Ernanda , Shelby Amrus Ernanda, Shelby Amrus Friscillia , Febrina Gumelar , Enggar Haq, Nabiila Ala Qoonita Najma HARI PURNOMO Hasibuan , Muhammad Effendy Nugraha Heri, Sutanto Herman Tolle Herpan Syafii Harahap Hidayat, Rudi Rakhmad Ibrahim , Ananto Suar Bhakti Irnanda , Miranthi Ayu Ismiarta Aknuranda Karmia Larissa Br Pandia Maliga , Helnida Anggun Masruroh Rahayu Muhamad Rasjad Indra Muhammad , Galang Mahasin Nanik Setijowati Nidia Suriani Prabowo , Bisma Dewanto Ari Pradhana, Satwika Pranowo, Muhammad Royyan Pratama , Senoadji Priana, Aan Jelli Purnama , Sari Dianita Putri , Firda Aunidiah Putri, Adecya Amaryllis Risa Rahmaditta , Allyssa Rahmalia Izzati, Fatma Rahmawati, Dessika Rahmawati, Dessika Raihana, Naura Salwa Raisa, Neila Riandono , Dody Rodhiyan Rakhmatiar Romadhoni, Muhammad Rifqy Savitri, Kania Aviandi Setianto , Catur Ari Shahdevi Nandar Kurniawan, Shahdevi Nandar Sinaga, Alexandra Maria Rossadwina Sriharkita Siraj, Resnanda Naufal siti nurlela Sitompul, Boyke Sri Andarini Sri Budhi Rianawati, Sri Budhi Sri Budi Rianawati Taqiyyah, Masyalia Hasna Tita Hariyanti Tri Wahju Astuti, Tri Wahju Widodo Mardi Santoso Widodo Mardi Santoso, Widodo Mardi Wirathmawati, Andina Yulia Damayanti Yuyun Yueniwati Zahra, Farah Shabri Alifia Zamroni Afif