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All Journal TEKNIK Medical Journal of Indonesia SITEKIN: Jurnal Sains, Teknologi dan Industri Majalah Kesehatan FKUB Indonesian Journal of Global Health research Narra J Go-Integratif : Jurnal Teknik Sistem dan Industri Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) MDP Student Conference Bata Ilyas Educational Management Review
Hendri Wijaya, Hendri
Department Of Pediatrics, Faculty Of Medicine, Universitas Sumatera Utara, H. Adam Malik General Hospital, Medan
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Other

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Accuracy of Hemoglobin Measurement using the SD Biosensor Standard G6PD Analyzer as Point-of-Care in Pediatric Populations in Malaria-Endemic Regions Effendi, Kevin; Siregar, Rosmayanti Syafriani; Wijaya, Hendri; Siregar, Olga Rasiyanti; Wahyuni, Arlinda Sari; Pasaribu, Ayodhia Pitaloka
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6918

Abstract

Background: Malaria remains a significant public health concern, particularly in endemic regions, is frequently associated with anemia in children. Accurate hemoglobin measurement is crucial for diagnosing anemia, especially in resource-limited settings. This study compares the accuracy of SD Biosensor Standard G6PD Analyzer with Hemocue HB301 System for hemoglobin measurement among children in malaria-endemic areas. Objective: To determine the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (LR+), negative likelihood ratio (LR-), pretest odds, post-test odds, and overall accuracy of the SD Biosensor Standard G6PD Analyzer compared to the Hemocue HB301 System. Method: This cross-sectional diagnostic study involved 325 children aged 6-18 years in Kualuh Leidong District. Secondary data were obtained from a previous study conducted in August 2024, using a total sampling technique. Result: The mean hemoglobin level measured by SD Biosensor Standard G6PD Analyzer (14,22±2,21 mg/dL) was higher than that measured by Hemocue HB301 System (13,45±1,63 mg/dL), with significant difference (p=0,001). The prevalence of anemia detected by SD Biosensor and Hemocue was 12,3% and 11,4%, respectively. The SD Biosensor Standard G6PD Analyzer demonstrated a sensitivity of 70,27%, specificity of 95,14%, PPV of 65%, NPV of 96,14% and an overall accuracy of 92,31%. Conclusion: The SD Biosensor Standard G6PD Analyzer exhibited relatively low sensitivity but high specificity compared to Hemocue HB301 System in measuring hemoglobin levels among children in malaria-endemic areas. Further research is needed to compare both devices against the gold-standard automated hematology analyzer and to identify the factors influencing measurement accuracy. Keywords: Anemia, Hemocue HB301 System, Hemoglobin, Malaria, SD Biosensor Standard G6PD Analyzer
Co-Authors Adam, Abdullah S. Adisty, Revinia Agung Prayudha Hidayat Angelino, Kevin Annisa Kartinawati Ayodhia P. Pasaribu, Ayodhia P. Dardanella, Derry Daulay, Rini S. Dillon, Erloy Doni Yusri Dyah Ari Wulandari Effendi, Kevin Fany Apriliani Farah, Sara Farisi, Ahmad Fery Setiawan Indrawan, Purana Kollins, Fini Lie, Tommy Lubis, Inke ND. Nababan, Kristo A. Novia Rahmawati OLGA RASIYANTI SIREGAR, OLGA RASIYANTI Pangestu, Fattah Jati Paramita, Deryne A. Paramita, Deryne Anggia Pasaribu, Ayodhia Pitaloka Pasaribu, Ira Nurhasanah Restuti Hidayani Saragih Rina Yunita Risyahadi, Sazli Tutur Rita Evalina S. Suripin Sesar Husen Santosa Sinaga, Adinda Alleyda Sinaga, Antonya Rumondang Sinaga, Bintang Yinke Magdalena Siregar, Rosmayanti Syafriani Suhendi Irawan Syahril Pasaribu, Syahril Tjoa, Kevin Tondy, Tondy Wahyuni, Arlinda Sari