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Profil Drud Related Problems (DRPs) pada Pasien Diabetes Melitus Tipe 2 di Instalasi Rawat Jalan Rumah Sakit X Provinsi Nusa Tenggara Barat Tahun 2018 Candra Eka Puspitasari; Baiq Sofianti Annisa; Siti Rahmatul Aini; Arfi Syamsun; Zulkarnain; Melda Putri Zakiyah
Pharmaceutical Journal of Indonesia Vol. 9 No. 1 (2023)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2023.009.01.6

Abstract

Type 2 diabetes mellitus’s patients often receive polypharmacy therapy to prevent complications, but this has the potential effect to increase Drug Related Problems (DRPs). This study aims to evaluate the incidence of DRPs in type 2 diabetes mellitus’s patients at the Outpatient Installation of X Hospital in NTB Province in 2018. This research was conducted with a retrospective cross-sectional design with a sampling technique, namely purposive sampling. After the data is obtained, then classification of the problems and causes of DRPs is carried out based on the Pharmaceutical Care Network Europe Foundation Version 8.03 (PCNE V8.03). The results obtained 112 patients where 80 patients experienced DRPs events with a total of 224 DRPs events. The pattern of anti-diabetic use was dominated by the Biguanide group, namely Metformin (33.85%), followed by Insulin (29.75%), and Sulfonylureas (28.21%). Insulin use was dominated by Insulin Aspart (13.33%), while Sulfonylureas were dominated by Glimepiride (25.13%). Therefore, DRPs that occur sequentially are the categories of adverse drug effects that may occur (66.52%), drugs without indication (15.63%), drugs that are not appropriate according to guidelines/formularies (7.14%), symptoms or indications not treated (4.91%), the frequency of using the dose was insufficient (1.79%), the frequency of using the dose was too frequent (1.79%), the drug dose was too low (1.34%), too many drugs were prescribed for indications (0.45%) and the drug dose is too high (0.45%).
Co-Authors Adinda Citra Ahmad Taufik Ananda Rizkia Andini, Syabila Anisa Ansyori, Maz Isa Ardiana Ekawanti Arif Setyo Arnawati, Ida Ayu Astuti, Anies Dyaning Atmawati, Baiq Jatna Auliya, Rosmeiti Emma Ayu Santia Dewi Bagas Ekasangga Baiq Nadya Putri Maharani Baiq Sofianti Annisa Baiq Wanda Annisa Candra Eka Puspitasari Candra Eka Puspitasari Donna Diva Widyantari Dwi Astuti Wulandari Eka Arie Yuliyani Emira Alifia Eustachius Hagni Wardoyo Eva Triani Fathul Djannah Firdaus, Royan Alfian Hadyljinan Utomo, Danesh Hakim, Faradila Khoirun Nisa Hamsu Kadriyan Harahap, Ida Lestari Harahap, Ida Lestari Herlina, Lenny I Dewa Ayu Yulisa Prahasti, I Dewa Ayu Yulisa I Komang Gerudug, I Komang I Made Arya Yogiswara Mahayasa Ida Ayu Kirtiasih, Ida Ayu Ida Lestari Harahap Ida Lestari Harahap Ida Lestari Harahap Ida Lestari Harahap Ida Lestari Harahap Ima Arum Lestarini Indana Eva Ajmala Januarman, Januarman Januarman, Januarman Januarman, Januarman Januarman, Januarman Januarman, Januarman Januarman, Januarman Jumsa, Muhammad Rizkinov Jurnal Pepadu Laily, Novita Shalatiah LALU ABDURRACHMAN WAHID Lalu Ahmad Gamal Arigi Leni Herlina Lenny Herlina Lenny Herlina Lenny Herlina Lina Nurbaiti, Lina Luthfiyah Kamila Melda Putri Zakiyah Muhammad Faeyza Muharrom, Siti Nurul Muthia Cenderadewi, Muthia Nabila Indah Shofiyanti Ni Made Amelia Ratnata Dewi Ni Pt Wr Pradnya Nirmala Putri Nisa, Hayatin Nur Oktia Nirmalasari, Nur Oktia Nurhidayati Nurhidayati Nurul Hidayati Oci Qonita Londo Woro Pandu Tridana Sakti, Pandu Tridana Pramesti, Evane Dyahayu Prima Belia Fathana Puji Arrohman, Puji Pujiarohman Pujiarohman Pujiarohman Pujiarohman Pujiarohman Pujiarohman, Pujiarohman Pujiarrohman Pujiarrohman Pujiarrohman Puspasari Mahadewi Putri, Sandra Yuliana Andini Putri, Yolanda Satriani Putu Grandiva Mahasuary PW, Ni Putu Ayu Dewanthi Rahayuningrum, Nurekayani Rendraswara, Wanda Rifki Ahmad Eka Putra Rika Hastuti Setyorini Rina Lestari Rohadi Rohmayana, Sri Royani Widiyastuti Sari, Surya Meka Novita Shania Hafista Siti Rahmatul Aini Syari, Mayuarsih Kartika Theophany Margareta Kurniawan Ulfa Ramdhani Vini Fardila, Vini Wahyu Sulistya Affarah, Wahyu Sulistya Wulandari, Rizka Yusuf Alfian Yuvita Dewi Priyatni, Yuvita Dewi Zulkarnain