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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Biosains Pascasarjana Jurnal Penelitian Kesehatan Suara Forikes Jurnal Farmamedika (Pharmamedica Journal) BERNAS: Jurnal Pengabdian Kepada Masyarakat Anakes: Jurnal Ilmiah Analis Kesehatan Jurnal EduHealth Jurnal Kesehatan Prisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Jurnal Pengabdian Masyarakat Waradin Innovative: Journal Of Social Science Research Jurnal Pengabdian Kepada Masyarakat: Kesehatan (JPKMK) Faedah: Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia Jurnal Pengabdian Masyarakat Journal of Medical Laboratory in Infectious and Degenerative Diseases Sadewa: Jurnal Pengabdian Masyarakat
RIAN ANGGIA DESTIAWAN
UNIVERSITAS dr. SOEBANDI
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Effectiveness of The Larvicide Combination Extract of Basil (Ocimum basilicum) Leaves And Soursop (Annona muricata) Leaves Against Aedes aegypti Larva Shafrina Rohma, Hanna; Mufidah, Hartalina; Anggia Destiawan, Rian; Trianggaluh Fauziah, Dina
Journal of Medical Laboratory in Infectious and Degenerative Diseases Vol. 2 No. 2 (2024): Desember
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jmid.v2i2.28

Abstract

Background: Dengue hemorrhagic fever (DHF) is an acute febrile illness caused by dengue virus infection which is transmitted through the bite of the Aedes aegypti mosquito. An alternative method that can be used is a vegetable larvicide to eradicate Aedes aegypti larvae. Basil leaf extracts (Ocimum basilicum) and soursop leaves (Annona muricata) contain flavonoids, saponins, alkaloids, tannins and essential oils as larvicide compounds. Purpose: This study aims to determine the effectiveness of the larvicidal combination of basil (Ocimum basilicum) and soursop (Nnona muricata) leaf extracts against Aedes aegypti larvae at concentrations of 5%, 10%, 15% and 20%. Methods: This type of research is descriptive quantitative research with an experimental design. This study used 6 samples of Aedes aegypti larvae at each concentration. The treatment stage was carried out by adding a combination of basil (Ocimum basilicum) and soursop leaf (Annona muricata) leaf extracts in concentrations of 5%, 10%, 15% and 20% into an Erlenmeyer flask containing larvae and distilled water. Calculate the number of deaths at 30 minutes, 1 hour, 2 hours and 3 hours. Results: The results of this study showed larval mortality at a concentration of 5%, namely 0 larvae in 30 minutes, 1 larva in 1 hour, 2 larvae in 2 hours and 3 larvae in 3 hours. Larval mortality at a concentration of 10% is 1 larva in 30 minutes, 2 larvae in 1 hour, 3 larvae in 2 hours and 0 in 3 hours. Larval mortality at a concentration of 15% is 2 larvae in 30 minutes, 3 larvae in 1 hour, 1 larva in 2 hours and 0 larvae in 3 hours. Larval mortality at a concentration of 20% was 3 larvae in 30 minutes, 3 larvae in 1 hour and 0 larvae in 2 and 3 hours. Conclusions: The combination of basil (Ocimum basilicum) and soursop leaf (Annona muricata) leaf extracts is most effective as a larvicide at a concentration of 20% with a death time of 30 minutes.
Edukasi Kesehatan Pengaruh Kualitas Tidur Terhadap Kadar Hb dan Imunitas Tubuh Pada Remaja Anas Fadli Wijaya; Rian Anggia Destiawan; Pratikah Verdianti
Jurnal Pengabdian Masyarakat Waradin Vol. 1 No. 3 (2021): September : Jurnal Pengabdian Masyarakat Waradin
Publisher : Sekolah Tinggi Ilmu Ekonomi Pariwisata Indonesia Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56910/wrd.v1i3.299

Abstract

Sleep quality is a state lived by an individual to produce freshness and fitness after waking up. If a person's sleep quality is poor it will cause a decrease in the body's immune system and Hb levels which causes the individual to feel easily tired, sleepy and susceptible to disease. Adolescents are identified as a population at high risk of experiencing sleep problems which disrupt sleep quality. Accumulated work and lifestyle are one of the factors causing poor sleep patterns in adolescents which makes it easier for them to experience sleep disturbances. Adolescents with high risk certainly need adequate knowledge regarding the importance of maintaining quality sleep related to the body's immune system and Hb levels. Increased knowledge and examination can be carried out by laboratory personnel with health counseling and laboratory tests. The purpose of this community service is to increase the knowledge of adolescents to maintain good quality sleep so that Hb levels and body immunity are maintained. This community service implementation method consists of three stages, namely the preparation, implementation, and evaluation stages. At the implementation stage, an examination of Hb levels and counting the number of types of leukocytes was carried out as well as education related to the effect of sleep quality on Hb levels and the body's immune system. As a result of community service, adolescents have obtained health status through laboratory tests and good knowledge about the effect of sleep quality on Hb levels and body immunity.
EDUKASI MASYARAKAT MANDIRI DESA SIAGA ANTI DIABETES AHDIAH IMROATUL   MUFLIHAH; Rian Anggia Destiawan
Jurnal SADEWA Vol 3 No 01 (2025): Sadewa: Jurnal Pengabdian Masyarakat
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/js.v3i01.841

Abstract

Diabetes mellitus is a disease or metabolic disorder characterized by increased sugar levels and accompanied by impaired metabolism of carbohydrates, lipids, and proteins. Common problems in the community are diabetes and hypertension. Diabetes can be prevented by eating a healthy diet and controlling blood sugar levels. One way to control blood sugar levels is to measure blood sugar levels using a tool, but the problem is that many people cannot use the tool. The community service aims to implement a community-based education program that facilitates the community in increasing knowledge about early detection and self-examination of Diabetes Mellitus. Methods In this study, diabetes mellitus education and demonstration of tools for detecting blood sugar levels. The results are community support to reduce diabetes levels by exercising, getting enough rest, and regularly checking blood sugar. The conclusion is that the community after education understands how to control blood sugar levels and conduct independent examinations.
Aktivitas Madu Trigona (Trigona sp) Terhadap Gambaran Infiltrasi Sel Radang di Dermis pada Tikus (Rattus novergicus) dengan Model Luka Bakar Rian Anggia Destiawan; Anas Fadli Wijaya; Ahdiah Imroatul Muflihah
Jurnal Penelitian Kesehatan SUARA FORIKES 2022
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf13nk342

Abstract

Burns are caused by chemicals, hot liquids and fires. Burns cause skin tissue necrosis, thus removing cell components including heat shock protein (HSP), monosodium urate, high-mobility group box protein 1 (HMGB1), extracellular ATP, and mitochondrial DNA including nucleic acids which are referred to as Damage Associated Molecules. Patterns (DAMPS). DAMPS cause increased infiltration of inflammatory cells into tissues. The purpose of this study was to determine the activity of trigona honey (Trigona sp) based on inflammatory cell infiltration in rats (Rattus novergicus) with the burn model. The research method was to group into 5 groups, including KN (negative control), K-1 (burns + placebo), K-2 (burns + silver sulfadiazine), K-3 (burns + 50% trigona honey), and K-4 (burns + 100% trigona honey), then stained with Hematoxylin Eosin (HE) to see the presence of inflammatory cell infiltration. Statistical analysis using the Kruskal Wallis and Mann-Whitney tests. Microscopically (inflammatory cell infiltration score) it showed that the KN group had a score of 0, group K-1 had a score of 4, group K-2 had a score of 2, groups K-3 and K-4 had a score of 4 and 2. statistically, there was no difference between groups. The conclusion of this study is that 100% trigona honey can reduce inflammatory cell infiltration in the dermis area of skin that has experienced burns.Keywords: burns, trigona honey, silver sulvadiazine ABSTRAK Luka bakar disebabkan oleh bahan kimia, cairan panas, dan kebakaran. Luka bakar menyebabkan nekrosis jaringan kulit, sehingga mengeluarkan komponen-komponen sel diantaranya heat shock protein (HSP), monosodium urate, high-mobility group box protein 1 (HMGB1), ekstraseluler ATP, dan DNA mitokondria termasuk asam nukleat yang disebut sebagai Damage Associated Molecullar Pattern (DAMPS). DAMPS menyebabkan peningkatan infiltrasi sel radang ke dalam jaringan. Tujuan penelitian ini adalah mengetahui aktivitas madu trigona (Trigona sp) berdasarkan infiltrasi sel radang pada tikus (Rattus novergicus) dengan model luka bakar. Metode penelitian ini adalah melakukan pengelompokan menjadi 5 kelompok, di antaranya KN (kontrol negatif), K-1 (Luka bakar + placebo), K-2 (Luka bakar + silver sulfadiazine), K-3 (Luka bakar + madu trigona 50%), dan K-4 (Luka bakar + madu trigona 100%), kemudian dilakukan pewarnaan Hematoksilin Eosin (HE) untuk melihat adanya infiltrasi sel radang. Analisa statistik menggunakan uji Kruskal Wallis dan Mann-Whitney. Secara mikroskopis (skor infiltrasi sel radang) menunjukkan bahwa pada kelompok KN nilai skoringnya 0, kelompok K-1 nilai skoringnya 4, kelompok K-2 nilai skoringnya 2, pada kelompok K-3 dan K-4 nilai skoringnya 4 dan 2. Namun secara statistik, tidak terjadi perbedaan antar kelompok. Kesimpulan dari penelitian ini adalah bahwa madu trigona 100% dapat menurunkan infiltrasi sel radang di daerah dermis pada kulit yang mengalami luka bakar.Kata kunci: luka bakar, madu trigona, silver sulvadiazine
PELATIHAN PEMBUATAN SNACK DARI DAUN PEPAYA JEPANG UNTUK MEWUJUDKAN LANSIA “SEHATI” (SEHAT DAN PRODUKTIF) Ayu Susanti, Dhina; Rian Anggia Destiawan
Jurnal SADEWA Vol 3 No 02 (2025): Sadewa: Jurnal Pengabdian Masyarakat
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/sadewa.v3i02.855

Abstract

Elderly people must maintain a healthy diet because they are very susceptible to disease. Therefore, education is needed about the importance of consuming healthy food and assistance in processing healthy food to realize SEHATI (Healthy and Productive) elderly people. There are many natural ingredients around the yard that can be processed into healthy dishes for the elderly. Japanese papaya leaves are widely planted in yards and are rarely used. Japanese papaya leaves contain flavonoids, alkaloids, tannins and saponins which are very useful as antioxidants and immunomodulators. This activity was carried out through counseling and practice of making healthy snacks with Japanese papaya leaves as the basic ingredient for 23 elderly people who participated in the SELANTANG (Sekolah Lansia Tangguh) Jember activity which took place at the Griya Mangli Housing Complex, Jember. The purpose of this PkM activity is for participants to better understand the importance of elderly health and to equip them with skills in making healthy snacks that can be consumed with family or sold to increase the economy so that they can contribute to realizing the elderly "SEHATI" (Healthy and Productive).
Gambaran Morfologi Sel Neutrofil Pada Pewarnaan Giemsa dengan Variasi Waktu Pada Larutan Pengencer Akuades Muflihah, Ahdiah Imroatul; Destiawan, Rian Anggia; Wijaya, Anas Fadli; Widia, Leny Yulia; sufi, Queen Nurul; Azizah, Laila Camelia Nur; Makki, Alisa Alfiya
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 10 No. 1 (2024): ANAKES: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v10i1.1470

Abstract

Giemsa staining is a microscopic staining technique that aims to identify the morphology of leukocyte cell types. One of the methods that uses giemsa staining is the method of examining peripheral blood smear preparations which aims to evaluate the calculation of leukocyte type. The dyeing quality of giemsa is greatly influenced by the type of diluent material, namely buffer and aquadest. This study aims to determine the morphological picture of neutrophil cells in giema staining with time variations in aquadest diluent solution. The method of this study was to take blood from adults aged 20-25 years and had no history of illness as many as 24 samples. It was divided into 2 dilution groups, namely pH buffer 6.8 and aquadest, where each dilution was divided into 4 groups, namely group 1 soaking the peripheral blood smear preparation for 10 minutes, group 2 soaking the peripheral blood smear preparation for 20 minutes, group 3 soaking the peripheral blood smear preparation for 30 minutes, group 4 soaking the peripheral blood smear preparation for 40 minutes. Then a qualitative analysis was carried out, namely by comparing the background of the preparation and the morphology of neutrophil cells microscopically in each group. The results of this study are that microscopically groups 1 and 2 have a clear preparation background, while in groups 3 and 4 the preparation background is dirty and there are neutrophil granules and morphology in groups 1 and 2 show dark blue neutropnhil cells, groups 3 and 4 show purple and bluish-purple neutrophil cells. The conclusion of this study is based on the background of the preparation, and the morphology of neutrophil cells, the group that has the best results is groups 1 and 2. Key words : Aquadest, eosinophil cells, eutrophil cells, Giemsa staining
Immunomodulator Effect of Cnidoscolus aconitifolius Leaves Extract on CD4+ and CD8+ Expression in Salmonella typhimurium infected mice Hidayati, Sholihatil; Susanti, Dhina Ayu; Destiawan, Rian Anggia; Muflihah, Ahdiah Imroatul; Handayani, Rizka; Anggitasari, Wima
Pharmaciana Vol. 14 No. 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.27050

Abstract

Typhoid fever is a common health problem in the community caused by Salmonella bacteria. The incidence rate of this infection will increase if a person's immune system is weakened. Plant extracts are generally considered to be potential immunomodulatory agents developed, which have smaller side effects. Research shows that Cnidoscolus aconitifolius leaves have medicinal properties including as hepatoprotective, antidiabetic, and anticardiovascular. The results of the antioxidant activity test show the results that Cnidoscolus aconitifolius leaves extract (CAE) has potential as an antioxidant with a very strong category. This study was conducted to determine the effect of giving Japanese papaya leaf extract on CD4+ and CD8+ expression in Babl/c mice induced by Salmonella typhimurium bacteria. The study was started by preparing 70% ethanol extract from Cnidoscolus aconitifolius leaves and preparing 30 Babl/C mice as experimental animals which were divided into 6 groups (healthy control, negative control, positive control and treatment group by giving CAE dose of 100 mg/kgbw, 200 mg/kgbw and 400 mg/kgbw). Induction was carried out by oral infection with Salmonella thypimurium bacteria. After 3 days the infected mice were treated orally once a day for 7 days. Evaluation of CD4+ and CD8+ expression was carried out using the flowcytometer method of the lymph organs. Data analysis was carried out by the Anova test followed by the post hoc test (Tukey) using the SPSS for Windows application. The results showed that giving CAE at doses of 100 mg/kgbw, 200 mg/kgbw and 400 mg/kgbw could increase the expression ratio of CD4+ and CD8+, whereas giving CAE at a dose of 400 mg/kgbw showed significantly different results (p<0.05) to the negative control. This shows that the CAE has potential as an immunomodulatory agent that can improve immune function.
The Effect of Differences Time On The Macroscopic Picture Of Giemsa Staining Using Aquades Diluent Muflihah, Ahdiah Imroatul; Rian Anggia Destiawan; Anas Fadli Wijaya; Lenny Yulia Widia Sari; Queen Nurul Sufi; Alisa alfiya makki; Laila Camelia
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (227.678 KB)

Abstract

Peripheral Blood Smear Preparation (SADT) is an examination used to see the structure and number of red and white blood cells, besides giemsa staining can be used for malaria examination. The quality of giemsa staining is influenced by one of which is the soaking time of the giemsa solution. The purpose of this study was to determine the quality of slides or blood smears based on the incubation duration of giemsa staining. This research method qualitatively performed giemsa staining on blood smears with different soaking times (10 minutes, 20 minutes, 30 meinit and 40 minutes) then compared with controls. Results showed that at minutes 10 and 20 the giemsa staining showed a smooth surface and no granules, at 30 and 40 minutes the giemsa staining showed a rough surface and many granules. The conclusion of this study was that 10 and 20 min giemsa soaking showed optimal staining of blood smear preparations.    
Pemanfaatan Tanaman Obat dalam Penanganan Masalah Kesehatan Masyarakat di Desa Gumuksari, Kalisat, Jember Hidayati, Sholihatil; Susanti, Dhina Ayu; Destiawan, Rian Anggia
Jurnal Pengabdian Masyarakat (JUDIMAS) Vol. 1 No. 2 (2023)
Publisher : Pusat Penelitian dan Pengabdian Masyarakat STIKes Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/judimas.v1i2.148

Abstract

Warga masyarakat di Desa Gumuksari sudah terbiasa memanfaatkan pekarangan yang berada di sekitar rumahnya untuk ditanami berbagai jenis tanaman. Dari berbagai macam tumbuhan yang hidup di pekarangan warga, banyak diantaranya yang merupakan tumbuhan yang dapat dipergunakan sebagai tanaman obat tradisional. Beberapa warga, kadang menggunakan tanaman-tanaman tersebut untuk mengobati keluhan kesehatan yang dirasakan, namun pemanfaatannya belum terlalu optimal karena selama ini penggunaan tanaman obat tradisional itu hanya didasarkan pada pendapat teman atau tetangga. Kegiatan penyuluhan telah dapat dilakukan dengan baik pada hari Minggu, tanggal 14 Agustus 2022. Hal ini terlihat dari keseriusan peserta dan sesi Tanya jawab yang terlihat manyarakat begitu antusias dengan menayakan beberapa pertanyaan. Penggunaan obat tradisional dalam mengatasi masalah kesehatan masyarakat merupakan solusi alternative terutama bagi masyarakat di desa yang memiliki tanah subur dan tanaman melimpah. Kemanjuran tanaman obat dalam mengatasi penyakit telah terbukti secara turun temurun dan telah direkomendasikan oleh pemerintah dan WHO.
Hubungan Kejadian Typoid Fever dengan Kebersihan Diri Pada Usia 5-45 Tahun di Tulungagung Nurjanah, Mutia Hariani; Wijaya, Anas Fadli; Safitri, Yunita Diyah; Santoso, Arif; Destiawan, Rian Anggia
Innovative: Journal Of Social Science Research Vol. 4 No. 6 (2024): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v4i6.14007

Abstract

\ Typoid fever adalah infeksi bakteri yang disebabkan oleh bakteri S. Typhi dengan mengkonsumsi makanan atau air yang terkontaminasi oleh feaces atau saluran kemih yang terdapat bakteri. Gangguan ini menular langsung yang disebut dengan transmissible disease. Gejala utama infeksi ialah mual, sakit perut, dan buang air besar diare maupun sembelit dengan disertai demam tinggi. Kekambuhan mungkin lebih ringan dibandingkan infeksi awal, namun dapat menyebabkan gejala yang lebih parah dibandingkan infeksi awal.  Kekambuhan ini bisa ringan atau berat dan bisa terjadi hingga dua atau tiga kali. Selain itu, Komplikasi dapat terjadi da berdampak jika demam tifoid jika tidak ditangani dengan tepat sasaran. Tujuan untuk mengetahui hubungan kejadian typoid fever dan kebersihan diri. Metode menggunakan metode pendekatan cross secssional dengan jumlah responden sebanyak 30 partisipan. Hasil menggunakan uji chi square menunjukkan bahwa kejadian  typoid fever dan kebersihan diri p = 0.001 menunjukkan adanya hubungan demam tifoid dengan kebersihan diri dan lingkungan. Kesimpulan : Terdapat hubungan antara typhoid fever dan kebersihan diri. Partisipan paling banyak perempuan rentang usia paling tinggi 5-15 tahun.
Co-Authors Agustin, Ayu Tri Ahdiah Imroatul Muflihah AHDIAH IMROATUL MUFLIHAH Alisa Alfiya Makki Amalia, Nabila Anas Fadli Wijaya Angger Putri M. Soleh, Ayu Anggitasari, Wima Anggraeni, Linda Suci Arif Santoso Asista Indarusanti, Delvia Ayu Susanti, Dhina Azizah, Laila Camelia Nur Dhina Ayu Susanti Dhina Ayu Susanti Dhina Ayu Susanti Hariani Nurjanah, Mutia Hayati, Farhatul Hidayati, Sholihatil Kalyana Meta, Nilanda Laila Camelia Lenny Yulia Widia Sari M. Elyas Arif Budiman Makki, Alisa Alfiya Mufidah, Hartalina Mutia Hariani Nurjanah Nabila, Talitha Vanian Ni Ketut Yuliana Sari Nosa Ika Cahyariza Nosa Ika Cahyariza Novarina Sulsia Ista'In Ningtyas Nurjanah, Mutia Hariani Pratikah Verdianti Purwati, Aliyah Queen Nurul Sufi Rahmawati, Septyana Eka Rizka Handayani Rizka Handayani Safitri, Yunita Diyah Salsa Safitri, Avrillia Sandi Basuki, Aditya Occy Sati, Wima Anggita Shafrina Rohma, Hanna Sholihatil Hidayati Sholihatil Hidayati Sholihatil Hidayati Siti Huzaimah Soleh, Ayu angger Putri M. sufi, Queen Nurul Susanti, Dhina Ayu Tiara Wahyu Norbaity Trianggaluh Fauziah, Dina Warda Atika Silvana Widia, Leny Yulia Wima Anggitasari