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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana Health Notions Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Biomolecular and Health Science Journal Cermin Dunia Kedokteran Cermin Dunia Kedokteran
Trisniartami Setyaningrum
Departemen/ SMF Ilmu Kesehatan Kulit Dan Kelamin, Fakultas Kedokteran Universitas Airlangga/ RSU Dr. Soetomo, Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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The Effect of Lifestyle on Skin Aging Yasmin Adzra Nabila; Damayanti Damayanti; Samsriyaningsih Handayani; Trisniartami Setyaningrum
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 2 (2021): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.2.2021.110-115

Abstract

Background: Skin aging is a natural process, and it has many causes. Skin aging can be a result of a process of deterioration of the skin structure and a decrease in normal skin function. As much as 97% of skin aging factors is extrinsic, while the remaining 3% of the factors is intrinsic. Extrinsic factors are closely related to lifestyle; therefore it is necessary to further investigate the effects of lifestyle on skin aging. Skin aging may not have a direct correlation to mortality but the process of aging itself can lead to depression, demoralization, and shame at the extreme to the point of accepting the changes that occur with age. This shows that aging plays an important role in decreasing the quality of human life and youth well-being index, especially in women. Purpose: To determine the effects of lifestyle on skin aging. Methods: This was a case-control study. A case means a person with heavy aging, and control means an individual with mild aging. The data were obtained from medical records and anamneses. Data on lifestyle were collected through interviews with open-ended questions. Subjects who met the inclusion criteria were shortlisted, and their skins were examined as per the Glogau scale. Result: Multivariate test results showed significant results on the variable UV light exposure (p = 0.017), use of sunscreen (p = 0.002), use of anti-aging cream (p = 0.036), and Vitamin D (p = 0.040) against skin aging. Meanwhile, other variables showed no significant results. Conclusion: Lifestyle has an important role in the occurrence of skin aging. However, an in-depth research is needed to determine how many external factors affect skin aging.
Comparison of the Efficacy of Topical Clindamycin versus Niacinamide in the Treatment of Mild to Moderate Acne Vulgaris: a Systematic Review Eden Leonita; Trisniartami Setyaningrum; Mohammad Fathul Qorib; Damayanti -
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.15-22

Abstract

Background: Acne vulgaris (AV) is one of the most common skin diseases among teenagers and is treated based on its severity. Mild acne is treated with topical agents, while moderate and severe acne are treated with a combination of topical and systemic agents. Topical agents that are often used for acne are antibiotics, such as topical clindamycin. Widespread use of antibiotics to treat AV causes resistance problems. Therefore, alternative therapies are needed to prevent resistance to topical clindamycin, such as topical niacinamide, which has anti-inflammatory effects without inducing resistance problems. Purpose: To compare the efficacy of topical clindamycin and topical niacinamide in mild to moderate AV. Methods: In this systematic review, a literature search was carried out through 6 databases, following PRISMA 2020 guidelines. Inclusion criteria were written in English or Indonesian, published in 2010-2020, randomized controlled trial (RCT) study design, conducted on human samples, and discussed the efficacy comparison of topical clindamycin and niacinamide in mild to moderate AV. Studies that were not accessible in full-text and based on secondary data were excluded. Quality and risk of bias assessments were done using The Jadad Scale and Risk of Bias 2 (RoB 2). Result: Acne severity was reduced significantly in both topical clindamycin and niacinamide groups, and there was no efficacy difference between these groups. Both topical clindamycin and topical niacinamide can cause mild side effects. Conclusion: Topical niacinamide can be an alternative therapy to topical clindamycin because they are both effective in treating mild to moderate AV.
Skin Aging Profile in Tertiary Hospital: a Descriptive Study Tasya Wikassa; Damayanti Damayanti; Irfiansyah Irwadi; Trisniartami Setyaningrum; Rahmadewi Rahmadewi; Diah Mira Indramaya; Menul Ayu Umborowati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.36-45

Abstract

Background: Skin aging is a physiological process that involves changes in skin cells and tissues due to abnormal mechanisms and decreased tissue function caused by both intrinsic and extrinsic factors. Skin aging has different clinical manifestations in each individual, which were classified using Glogau's photoaging classification. Purpose: The objective of this descriptive observational study is to evaluate the profile of skin aging patients at Dr. Soetomo General Hospital Surabaya from January – December 2019. Methods: This study utilized a total sampling technique from data obtained from the patients' medical records, which included age, gender, occupation, anamnesis, physical examination, diagnosis, and treatment received by patients. This research has been reviewed by the Ethics Committee at Dr. Soetomo General Hospital Surabaya (0438/KEPK/XII/2021). Result: Based on data obtained from medical records, 415 samples of skin aging patients were collected. The highest number of cases occurred among patients aged 45 - < 60 years. Most patients were female, and the majority of patients’ occupations were private employees. History taking findings include the most common complaint, namely dull skin, with the most precipitating factors discovered in patients, namely exposure to sunlight and pollution. Wrinkles were the most common physical examination finding in patients, with Glogau's photoaging III being the most common diagnosis. Most patients were treated with photoprotection in the form of sunscreen. Conclusion: With the increase of public awareness about appearance, as well as human health and quality of life, skin aging is receiving adequate attention nowadays, with sun exposure being the most common precipitating factor.
Distribution Genotype High Risk (HR) And Low Risk (LR) Human Papillomavirus (HPV) at Condyloma Acuminata Gondo Mastutik; Alphania Rahniayu; Dwi Murtiastutik; Afria Arista; Trisniartami Setyaningrum; Nabiha Missaoui; Suhartono Taat Putra
Biomolecular and Health Science Journal Vol. 4 No. 1 (2021): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v4i1.26250

Abstract

Introduction: Condyloma acuminata that is also known as genital warts are one of the most common sexually transmitted that caused by infection of Human papillomavirus (HPV). Persistent infection of Low Risk (LR) or High risk (HR) HPV is a risk factor for progress into benign or malignant cancer. The objective is to analyze distribution of genotype LR-HPV and HR-HPV at condyloma acuminata in anogenital region. Methods: A cross sectional study using were 36 lesions from men and women of condyloma acuminata patients. All subject signed the informed consent and ethic obtained from our institution, number 382/Panke.KKE/V/2016. The specimen was used to histopathological examination and to identified 40 genotypes of HPV using a reverse line blot assay.Results: The All patients were diagnosed as condyloma acuminata, some with focus dysplasia and koilocytosis. All patients were positive for HPV, including LR-HPV were HPV 6, 11, 42, 54, 61, 81,87,89 and HR-HPV were HPV 18, 26, 45, 51, 52, 66, 67, 68B, 69, 82. The single infection of LR-HPV was 44.4%, multiple infection LR/LR-HPV was 13,9% and the multiple infection of LR/HR-HPV was 41.7%. The LR-HPV infected 70,6% and HR-HPV infected 29,4%.  Conclusion: LR-HPV is the major infection of condyloma acuminata, in single infection or multiple infection with HR-HPV. The most common infections were HPV 11, followed by HPV 6, HPV 18, HPV 51, and HPV 82. The determination of genotype of HPV can be used to predict the malignant transformation.
Gray Patch Tinea Capitis Caused by Microsporum canis Febrina Dewi Pratiwi; Trisniartami Setyaningrum
Cermin Dunia Kedokteran Vol 47, No 10 (2020): Optalmologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i10.1087

Abstract

Background: Tinea capitis (TC) is the most common dermatophytosis of childhood. Case: A 3-year-old boy came with a three-week history of whitish rash and baldness. Physical examination found whitish, ill-defined patches and plaques with focal area of scaling and hyperkeratosis on the scalp (vertex region) and alopecia. Woods light examination revealed green fluorescence of infected hairs, and KOH prep revealed an ectothrix pattern of hair shaft invasion by fungal elements. Fungal growth by culture on Sabouraud dextrose agar with chloramphenicol and cycloheximide for 3 weeks found growth of M. canis. The treatment was griseofulvin 1x375 mg and ketoconazole 2% shampoo twice weekly. Complete clinical clearance was obtained after 8 weeks .Latar Belakang: Tinea Kapitis (TK) adalah dermatofitosis terbanyak pada anak. Kasus: Anak berusia 3 tahun dengan keluhan bercak putih dan botak di kepala sejak 3 minggu. Pemeriksaan fisik mendapatkan bercak keputihan, batas jelas dengan sisik tipis dan hiperkeratosis di area vertex kepala dan alopecia tanpa pustul, erosi, indurasi, atau inflamasi berat. Pemeriksaan lampu Wood menunjukkan floresensi hijau terang dan pemeriksaan KOH menunjukkan pola ectothrix elemen jamur pada sampel batang rambut. Kultur jamur pada Sabouraud dextrose agar dengan kloramfenikol dan sikloheksimid selama 3 minggu ditemukan pertumbuhan jamur Microsporum canis. Terapi griseofulvin oral 1x375 mg dan shampo ketoconazol 2% dua kali seminggu. Pasien sembuh setelah pengobatan 8 minggu.
Pemeriksaan Imunohistokimia untuk Mengungkap Patogenesis Vitiligo Willy Sandhika; Ryski Meilia Novarina; Trisniartami Setyaningrum
Cermin Dunia Kedokteran Vol 43, No 10 (2016): Anti-aging
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v43i10.872

Abstract

Vitiligo merupakan penyakit kulit yang ditandai dengan area putih yang makin luas. Patogenesis penyakit vitiligo melibatkan berbagai etiologi yang saling berkaitan seperti genetik, autoimun dan inflamasi. Pemeriksaan imunohistokimia pada bahan biopsi kulit penderita vitiligo meliputi pemeriksaan antibodi CD3, CD8, TNF-α, IL-17 dan IL-17RA, CD117, NALP1, Langerin serta CD11c dapat mengungkap patogenesis penyakit sehingga dapat membuka jalan untuk terapi yang sesuai.Vitiligo is a skin disorder characterized by progressive white macules. The pathogenesis involves various interrelated etiologies such as genetic, autoimmune and inflammation. Immunohistochemical examination on skin biopsy using antibody CD3, CD8, TNF-α, IL-17 and IL-17RA, CD117, NALP1, Langerin and CD11c may reveal the pathogenesis of the disease to facilitate appropriate therapy.
Gray Patch Tinea Capitis Caused by Microsporum canis Febrina Dewi Pratiwi; Trisniartami Setyaningrum
Cermin Dunia Kedokteran Vol. 47 No. 8 (2020): Oftalmologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i8.582

Abstract

Background: Tinea capitis (TC) is the most common dermatophytosis of childhood. Case: A 3-year-old boy came with a three-week history of whitish rash and baldness. Physical examination found whitish, ill-defined patches and plaques with focal area of scaling and hyperkeratosis on the scalp (vertex region) and alopecia. Woods light examination revealed green fluorescence of infected hairs, and KOH prep revealed an ectothrix pattern of hair shaft invasion by fungal elements. Fungal growth by culture on Sabouraud dextrose agar with chloramphenicol and cycloheximide for 3 weeks found growth of M. canis. The treatment was griseofulvin 1x375 mg and ketoconazole 2% shampoo twice weekly. Complete clinical clearance was obtained after 8 weeks . Latar Belakang: Tinea Kapitis (TK) adalah dermatofitosis terbanyak pada anak. Kasus: Anak berusia 3 tahun dengan keluhan bercak putih dan botak di kepala sejak 3 minggu. Pemeriksaan fisik mendapatkan bercak keputihan, batas jelas dengan sisik tipis dan hiperkeratosis di area vertex kepala dan alopecia tanpa pustul, erosi, indurasi, atau inflamasi berat. Pemeriksaan lampu Wood menunjukkan floresensi hijau terang dan pemeriksaan KOH menunjukkan pola ectothrix elemen jamur pada sampel batang rambut. Kultur jamur pada Sabouraud dextrose agar dengan kloramfenikol dan sikloheksimid selama 3 minggu ditemukan pertumbuhan jamur Microsporum canis. Terapi griseofulvin oral 1x375 mg dan shampo ketoconazol 2% dua kali seminggu. Pasien sembuh setelah pengobatan 8 minggu.
Cutaneous Manifestations in End-Stage Renal Disease (ESRD) Amira Suryani Rahmatika; Trisniartami Setyaningrum; Sawitri Sawitri; Evy Ervianti; Damayanti Damayanti
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 01 (2024): Qanun Medika Vol 08 No 01 January 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i01.19371

Abstract

Skin can reflect systemic conditions due to abnormalities in internal organs, including kidney disorders. Cutaneous manifestations are common in patients with end-stage renal disease (ESRD). It can be severe and negatively impact a patient's quality of life. Clinicians can effectively manage ESRD by closely examining the patient's skin and nails, improving the patient's quality of life, and reducing mortality and morbidity. Clinicians can be more aware of ESRD by examining the patient's skin and nails closely so proper management can be performed and the patient's quality of life can be improved. This review aims to increase understanding of common cutaneous manifestations in ESRD for early recognition and better management.  Cutaneous manifestations in ESRD are divided into specific and nonspecific manifestations. Specific manifestations include acquired perforating dermatosis (APD), bullous disease (porphyria cutanea tarda and pseudoporphyria), metastatic calcification (calcinosis cutis and calcific uremic arteriolopathy), and nephrogenic systemic fibrosis. Nonspecific manifestations include pruritus, xerosis, skin pigmentation changes, nail disorders, purpura, hair disorders, oral mucosal changes, skin infections, and other skin manifestations. These manifestations range from benign and asymptomatic to serious conditions that negatively impact life quality. In conclusion, Early detection and treatment of cutaneous manifestations in patients with ESRD are crucial for reducing morbidity and mortality and also improving patients' quality of life.
Efficacy and Side Effects of Fractional Carbon Dioxide Laser for Acne Scars, Keloids, and Striae Albae in the Dermatovenereology Clinic of Tertiary Hospital: A Retrospective Study Pramitha, Riezky Januar; Zulkarnain, Iskandar; Ervianti, Evy; Rahmadewi, Rahmadewi; Hidayati, Afif Nurul; Budiono, Budiono; Indramaya, Diah Mira; Setyaningrum, Trisniartami; Citrashanty, Irmadita; Sari, Maylita; Umborowati, Menul Ayu; Kusumaputra, Bagus Haryo; Listiawan, Muhammad Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 1 (2021): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.1.2021.19-27

Abstract

Background: Fractional Carbon Dioxide (CO2) LASER has better efficacy compared to conventional LASER in treating scar tissue such as acne scars, keloids, and striae albae. However, a population with darker skin has a higher risk of side effects, especially in post-inflammatory hyperpigmentation. Purpose: To evaluate the efficacy and side effects of fractional CO2 LASER in new patients with acne scars, keloids, and striae albae in the Dermatovenereology outpatient clinic. Methods: Retrospective analysis was done on 42 medical records of patients who met the inclusion criterion, which was those who have undergone fractional CO2 LASER treatments. The efficacy and side effects of the therapy were identified and analyzed using the Statistical Package for Social Sciences (SPSS) version 17 program. Result: A total of 42.9% of patients underwent fractional CO2 LASER treatments for acne scars, while 31% and 26.1% of patients received treatments for keloids and striae albae, respectively. There was a statistically significant decrease in the degree of acne scar (2.72 ± 0.83), keloid height (2.2 ± 0.405), and striae width (0.39 ± 0.02). The statistically significant side effects were hyperpigmentation (59.5%), crustae (26.2%), erythema ≥ for 4 days (19%), and new acne (19%). Conclusion: Fractional CO2 LASER was effective for treating scar tissue (acne scars, keloids, and striae albae) with a higher incidence of side effects in population with darker skin and post-inflammatory hyperpigmentation.
Contact Dermatitis Knowledge Level in Batik Workers of Desa Batik, Tanjung Bumi, Bangkalan, Madura Prakoeswa, Cita Rosita Sigit; Rahmadewi, Rahmadewi; Setyaningrum, Trisniartami; Damayanti, Damayanti; Anggraeni, Sylvia; Mappamasing, Hasnikmah; Umborowati, Menul Ayu
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 2 (2021): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.2.2021.93-95

Abstract

Background: Batik has been declared as a humanitarian heritage for oral and non-cultural culture. The increasing demand for batik may have a negative impact as the industry utilizes chemical agents. Hazardous chemical exposure to the skin in the batik industry may result in a high risk of occupational contact dermatitis. This study was conducted to find out the social determinants of health. Purpose: This study aims to assess the level of knowledge of the batik workers before and after health education about occupational contact dermatitis. Methods: This was an observational interview study, and the data were collected using questionnaires. This study involved 30 batik workers.  We assessed the level of knowledge before and after the health education about occupational contact dermatitis. Result: There were 4 (13.3%) male participants and 26 (86.7%) female participants. The mean score of the pre-test was 66.98±10.10, and the post-test was 77.77±13.53 (p<0.05). Conclusion: The result showed a significant difference between batik workers' knowledge before and after health education about contact dermatitis.
Co-Authors Abdul Karim Ade Fernandes Afif Nurul Hidayati, Afif Nurul Afria Arista Afria Arista Afria Arista, Afria Agatha Anindhita Ayu Ardhaninggar Alarik L., Albertus Alphania Rahniayu Amanda Gracia Manuputty Amira Suryani Rahmatika Anggraeni, Sylvia Arifa Mustika Artaria Tjempakasari, Artaria Asrianti, Nur Ilma Astindari Astindari Astindari Astindari Astindari Astindari, Astindari Aulia Rafikasari Axelia, Presstisa Gifta Bagus Haryo Kusumaputra, Bagus Haryo Budiono Budiono Christina Avanti Cita Rosita Sigit Prakoeswa Cita Rosita SP Damayanti Damayanti - Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Deasy Fetarayani Diah Mira Indramaya Dinar Witasari Dwi Murtiastutik Dyah Ratri Anggarini Dyah Ratri Anggarini, Dyah Ratri Eden Leonita Eva Lydiawati Evy Ervianti Febrina Dewi Pratiwi Gondo Mastutik Hadiwidjaja, Farsha Naufal Hans Lumintang Hans Lumintang, Hans Lumintang,, Hans Hari Sukanto Hening Laswati Indiastuti, Danti Nur Irmadita Citrashanty Irmadita Citrashanty, Irmadita Irwadi, Irfiansyah Iskandar Zulkarnain Kathrin Kezia Henry Koesandrini, Kinanthi KUSUMASTUTI, ETTY HARY Linda Astari, Linda LINGGA, FEBRINA DEWI PRATIWI Lisa Aditama, Lisa Lutfia Ariska Ramadhani M. Yulianto Listiawan Mappamasing, Hasnikmah Marsudi Hutomo Marsudi Hutomo, Marsudi Maylita Sari Maylita Sari, Maylita Medhi Denisa Alinda, Medhi Denisa Menul Ayu Umborowati Menul Ayu Umborowati Menul Ayu Umborowati, Menul Ayu Nabiha Missaoui Ngesti Kumalasari, Diah Pramitha, Riezky Januar Puspowati, Erindah Putri Brillian Betrista Viorizka Qurnianingsih, Ema Rahmadewi Rahmadewi Rahmadewi Ramadhina, Anasya Putri Renata Mayangsari Ridha Ramadina Widiatma Rozita Maharani, Dinda Ryski Meilia Novarina Ryski Meilia Novarina Ryski Meilia Novarina, Ryski Meilia Samsriyaningsih Handayani Sawitri Sawitri Shakti Indraprasta Shakti Indraprasta, Shakti Shelma Maharani Shinta Dewi Rahmadhani Soetojo Suhartono Taat Putra Sulaksanaswastho Suyoso Sunarto, Olivia Awwalin Susanto, Ester Chateline Tasya Wikassa Tengku Riza Zarzani N Widyantari, Septiana Willy Sandhika Yasmin Adzra Nabila Yosi Charly Yuani Setiawati Yuli Wahyu Rahmawati Yuri Widia, Yuri Zada Febrial Effendy Zada Febrial Effendy, Zada Febrial