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All Journal Medical Journal of Indonesia The Indonesian Biomedical Journal Sari Pediatri Paediatrica Indonesiana Majalah Kedokteran Nusantara The Journal Of Medical School Sumatera Medical Journal Cermin Dunia Kedokteran Cermin Dunia Kedokteran

Munar Lubis

Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Sumatera Utara

Author-ID : 565435

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Comparison of pulmonary function test results before and after exercise in junior high school students Hendy Zulkarnain; Munar Lubis; Gabriel P.; Ridwan M. D.; Helmi M. Lubis
Paediatrica Indonesiana Vol 50 No 3 (2010): May 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi50.3.2010.176-80

Background During exercise, bronchoconstriction occurs dueÂ to heat loss from mucosal respiratory ract. Exercise test canÂ be performed to evaluate hyper-reactivity of the bronchus. TheÂ examination of pulmonary function is beneficial to confinn theÂ diagnosis, to determine precipitating factors, and to evaluateÂ disease severity and therapeutic response.Objective To compare pulmonary function test values before andÂ after exercise in junior high school students aged 13 to 15 years.Methods Experimental study of 60 junior high school studentsÂ from Bilah Hulu was performed using spirometry to evaluateÂ pulmonary function before and after eight minutes of exercise.Â Results Functional vital capacity (FVC) values before and afterÂ eightô€…minute exercise were 2.20 (SD 0.52) and 2.18 (SD 0.42),Â respectively. There was no significant difference between FVCÂ values before and after exercise (P>0.05). The mean forcedÂ expiratory volume in 1 second (FEV 1) values before and aftereight minutes of exercise were 2.21 (SD 0.42) and 2.13 (SD 0.50)Â respectively. There was no significant difference between FEV 1Â before and after the exercise (P>0.05).Conclusion Eightô€…minute exercise does not influence theÂ pulmonary function test results in healthy children.

The effect of iron versus iron plus zinc supplementation in children with malaria Bugis Mardina Lubis; Danny Dasraf; Nelly Rosdiana; Bidasari Lubis; Munar Lubis; Syahril Pasaribu; Chairuddin P Lubis
Paediatrica Indonesiana Vol 46 No 1 (2006): January 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi46.1.2006.7-12

Introduction Little is known about the potential interaction of ironand zinc given to increase hemoglobin and serum ferritin in chil-dren with malaria.Objective To study the effect of iron compared with a combination ofiron and zinc supplementation on children with falciparum malaria.Method Children with positive Plasmodium falciparum (n=86) wererandomly assigned to a daily supplementation of 6 mg iron/kg perday plus placebo or plus 10 mg zinc per day for 30 days. All childrenwere treated with the same regimen for the treatment of P. falciparum.Venous blood samples were collected at the start and end of thestudy. After 30 days of supplementation, the baseline and follow-upblood samples were analyzed.Results The increase of hemoglobin concentration in the ironplus placebo group was 0.58 g/dl, while in the iron plus zinc groupwas 0.09 g/dl (P<0.05). Serum ferritin concentration was high inboth groups before trial, yet there was no significant differenceafter iron supplementation.Conclusions Iron supplementation showed significant increasein hemoglobin concentration in children with positive P. falciparumtreated with the same regimen of treatment. Supplementation ofiron alone as well as iron plus zinc had been proven ineffective toiincrease serum ferritin in children with malaria.

Comparison of quinine-doxycycline and quinine-clindamycin for falciparum malaria in children Ditho Athos P. Daulay; Yunnie Trisnawati; Syamsidah Lubis; Munar Lubis; Syahril Pasaribu
Paediatrica Indonesiana Vol 51 No 4 (2011): July 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi51.4.2011.187-91

Objective To compare the efficacy of quinine-doxycycline to quinine-clindamycin combination, as treatment for uncomplicated falciparum malaria in children.Methods This randomized open labelled controlled trial was conducted from July to August 2007 at Mandailing Natal, Sumatera Utara Province. The subjects were 8 â€“ 18 year old children with positive Plasmodium falciparum from the peripheral blood smear. Simple randomization was performed to determine subject study into two groups of treatment, one group received quinine-clindamycin and the other received quinine-doxycycline treatment. The parasitemia was counted on day 0, 2, 7 and 28. We also observed the adverse effects of the antimalarial combination.Results Two hundred and forty six children who fulfilled the inclusion criteria were divided into two groups. All subjects completed the study. Cure rate achieved 100% from peripheral blood smear examination at the second day observation and showed no recrudescence at day 28th. (P=0.0001). During 28 days follow up, there were 21 (17.6%) patients suffered from headache, 18 (14.6%) vomit and 40 children (32.5%) suffered from tinnitus in quinine-doxycycline combination, compared to quinine-clindamycin combination group only 4 (3.3%) suffered from headache, 1 (0.8%) suffered from tinnitus and there was no vomiting experience in any patient (P < 0.0001).Conclusion Combination of quinine with either clindamycin or doxycycline are effective as an alternative antimalarial treatment. The combination of quinine-clindamycin is well tolerated than the combination of quinine-doxyciline, and this combination may be particular value for young children and pregnant women, as these two groups cannot receive doxycycline.

Blood pressure-to-height ratio for diagnosing hypertension in adolescents Kristina Ambarita; Oke Rina Ramayani; Munar Lubis; Isti Ilmiati Fujiati; Rafita Ramayati; Rusdidjas Rusdidjas
Paediatrica Indonesiana Vol 57 No 2 (2017): March 2017
Publisher : Indonesian Pediatric Society

Background Diagnosing hypertension in children and adolescents is not always straightforward. The blood pressure-to-height ratio (BPHR) has been reported as a screening tool for diagnosing hypertension.Objective To evaluate the diagnostic value of blood pressure-to-height ratio for evaluating hypertension in adolescents.Methods A cross-sectional study was conducted among 432 healthy adolescents aged 12-17 years in Singkuang, North Sumatera from April to May 2016. Blood pressure tables from the National High Blood Pressure Education Program (NHBPEP) Working Group on High Blood Pressure in Children and Adolescents were used as our standard of comparison. Sex-specific systolic and diastolic blood pressure-to-height ratios (SBPHR and DBPHR) were calculated. ROC curve analyses were performed to assess the accuracy of BPHR for discriminating between hypertensive and non-hypertensive adolescents. Optimal thresholds of BPHR were determined and validated using 2x2 table analyses.Results The accuracies of BPHR for diagnosing hypertension were > 90% (P<0.001), for both males and females. Optimal SBPHR and DBPHR thresholds for defining hypertension were 0.787 and 0.507 in boys, respectively, and 0.836 and 0.541 in girls, respectively. The sensitivities of SBPHR and DBPHR in both sexes were all >93%, and specificities in both sexes were all >81%. Positive predictive values for SBPHR and DBPHR were 38.7% and 45.2% in boys, respectively; and 55.9% and 42.4% in girls, respectively; negative predictive values in both sexes were all >97%, positive likelihood ratios in both sexes were all >5, and negative likelihood ratios in both sexes were all <1.Conclusion Blood pressure-to-height ratio is a simple screening tool with high sensitivity and specificity for diagnosing hypertension in adolescents.

Acute hepatitis at the Department of Pediatrics, School of Medicine, University of North Sumatera/Dr. Pirngadi Hospital, Medan Mahadi Mahadi; Syahril Pasaribu; Munar Lubis; Chairuddin P. Lubis
Paediatrica Indonesiana Vol 31 No 5-6 (1991): May - June 1991
Publisher : Indonesian Pediatric Society

Pirngadi Hospital revealing 41 cases of acute hepatitis, consisted of 61.0% boys and 39.0% girls. The majority of patients were below five years of age (68.3%). There were 37.1% cases with malnutrition. The common symptoms were fever, jaundice, vomiting and dark urine. On laboratory examination there were 10 cases with positive HBs Ag. Accompanying diseases were malnutrition, bronchopneumonia, anemia, bronchitis and pulmonary tuberculosis. A total of 63.4% oj patients were healed, 29.3% discharged against medical advice and 7.3 % died because of bronchopneumonia and hepatic coma.

Triiodothyronine levels and mortality in children with sepsis and septic shock Cynthea Prima Destariani; Munar Lubis; Melda Deliana; Gema Nazri Yanni
Paediatrica Indonesiana Vol 58 No 1 (2018): January 2018
Publisher : Indonesian Pediatric Society

Background Sepsis is the most common cause of death in infants and children. It can cause hormonal imbalances, such as euthyroid sick syndrome (ESS), which may increase the risk of death. Objective To evaluate a possible correlation between the level of triiodothyronine (T3) and mortality in children with sepsis and septic shock. Methods An observational cohort study was conducted on 80 children with sepsis and septic shock from October 2015 until January 2016Â in Haji Adam Malik General Hospital, Medan. Subjects underwent PELOD score and T3 examinationÂ on the first day admitted in Haji Adam Malik General Hospital. Chi-square test was used to analyze for a correlation between the T3 values and mortality.Â Results Of the 80 consecutive subjects, 39 (48.75%) had low T3 level on the first day. Of these 39 children, 36 (92.3%) died. Subjects with low T3 level had a 6.31 times higher risk of mortality(PR 6.31; 95%CI 2.99 to 13.28; P<0.001). Of the 31 subjects with high PELOD score, 23 (74.2%) had decreased T3 (PR=2.27; 95%CI 1.45 to 3.57; P<0.001). Conclusion Low T3 level has significant relationship with mortality in children with sepsis and septic shock.

Habitual snoring and primary enuresis in children Muhammad Adib Mahara; Oke Rina Ramayani; Elmeida Effendy; Munar Lubis; Rosmayanti Siregar; Beatrix Siregar; Rafita Ramayanti
Paediatrica Indonesiana Vol 58 No 3 (2018): May 2018
Publisher : Indonesian Pediatric Society

Background Obstructive sleep-disordered breathing is assumed to be associated with primary enuresis in children. Prolonged enuresis may cause developmental and emotional disorders, as well as poor school performance. Objective To determine the relationship between habitual snoring and primary enuresis in children. Methods A cross-sectional study was conducted in Muara Batang Gadis District, North Sumatera in April 2016. Subjects were children aged 5-14 years. The Sleep Disturbance Scale for Children (SDSC) questionnaire was used to measure the symptoms of sleep disordered breathing; the International Association Child and Adolescent Psychiatry and Allied Professions (IACAPAP) questionnaire was used to assess for the presence of primary enuresis. The questionnaires were answered by the childrenâ€™s parents. Data were analyzed using Chi-square and logistic regression tests. A P value of <0.05 was considered to be statistically significant. Results The mean age of 110 participants was 9.23 (SD 2.16) years. Twenty-seven (24.5%) subjects snored more than three nights per week (habitual snorers) and 18 (16.4%) subjects had primary enuresis. There was a significantly higher percentage of habitual snorers with enuresis than that of snorers without enuresis (55.5% vs. 18.4%, respectively) (P<0.05). Conclusion There is a significant relationship between habitual snoring and primary enuresis.

Treatment of Neonatal Tetanus with High Dosage Diazepam Tjut Dharmawati; Fauzi Rizal; Munar Lubis; Chairul Yoel; Syahril Pasaribu; Chairuddin P. Lubis
Paediatrica Indonesiana Vol 33 No 3-4 (1993): March - April 1993
Publisher : Indonesian Pediatric Society

A retrospective study on neonatal tetanus, among patients hospitalized at the pediatric ward of Dr. Pirngadi Hospital Medan, bad been conducted from january 1987 through December 1991. There were 75 cases out of 13,581 patients hospitalized (0.55%) in that period, consisting of 44 boys (58.66%) and31 girls (47 3 %) with an overall case fatality rate of 33.33%. Of 18 patients with an incubation period of 5 days or less, 12 (66.66%) died, while of 4 patients with an incubation period of more than 10 days, there were not any death at all. Diazepam had been given in a dosage of 10-40 mg/kg body weight/day . Diazepam of 10-19 mg/kg body weight/day was given to 4 cases, and the case fatality rate was 25% . Of 42 cases treated with diazepam of 30-40 mg/kg body weight/day, the case fatality rate was 42.85% The duration of hospitalization varied between ten hours to 34 days. All deaths (25 cases) occurred within the first seven days of hospitaltization. The most common accompanying disease was bronchopneumonia (6 cases). Endotracheal intubation were performed on 11 cases, while the mechanical ventilator in 1 case with a case fataliy rate of 27,27% and 0% respectively.

Patterns of Acid Base Balance and Plasma Electrolyte Concentrations in Post Surgical Digestive Patients T. Murad El Fuad; Efori Gea; Chaerul Yael; Munar Lubis
Paediatrica Indonesiana Vol 33 No 7-8 (1993): July - August 1993
Publisher : Indonesian Pediatric Society

Patterns of acid-base balance and plasma electrolyte concentrations of postsurgical digestive patients were studied retrospectively. The patients were treated at the Pediatric ICU Dr. Pirngadi Hospital, Medan, during the period of February 1991 through January 31 1992. There were 131 patients admitted to the Pediatric ICU, 67 (51.1 %) of them had had gastrointestinal surgery. Arterial blood gas and I or plasma electrolyte examinations were done in 92% of patients within 12 hours of admission. In 50 patients both blood gas and electrolyte concentration values were examined; 6 of them died. One out of 14 patients who had only serum electrolyte concentration values died. One out of 3 patients who had neither blood gas nor plasma electrolyte concentration values died. Acid-base imbalances were found in 66% of those 50 patients, consisting of 28% metabolic acidosis, 12% respiratory alkalosis, 8% respiratory acidosis, and 6% metabolic alkalosis. Hyponatremia was found in 68.4% of the survivors and in 2 out of 6 patients who died. No hypernatremia was found in any of the patients. Hypokalemia was found in 24.6% of patients survived; and none in those who died. Hyperkalemia was encountered in 24.6% of those who survived. The overall mortality of patients who had undergone gastrointestinal surgery in the Pediatric ICU, Pirngadi Hospital, was 8/67 (11.9%).

Neonatal Tetanus in the Department of Child Health Dr. Pirngadi Hospital, Medan in 1983-1984 Manihar D. Marbun; Johnny Arsyad; Munar Lubis; Endang D. Hamid; Chairuddin P. Lubis
Paediatrica Indonesiana Vol 28 No 3-4 (1988): March - April 1988
Publisher : Indonesian Pediatric Society

From January 1983 to December 1984 there had been prospective investigations of neonatal tetanus contracted by newborn infants treated at the Department of Child Health Dr. Pirngadi Hospital Medan. Seventy eight cases (4.28%) contracted neonatal tetanus out of 1821 hospitalized infants. Fifty cases were identified in 1983 and 28 cases in 1984. Fourty nine cases (62.8%) were delivered by traditional birth attendant (TBA), 18 cases (23.8%) by midwife/nurse, and 11 cases (14.10%) by others. The instruments used to cut the umbilical cord were razor blade (34.6%), scissor (33.33%), and sharp sliver bamboo (29.49%). There were 23 cases (29.49%) who used traditional medicine made from herb for umbilical cord treatment. None of the mothers was vaccinated with tetanus toxoid. Most of the parents had only elementary school education, 42.32% fathers, and 71.79% mothers. Based on this study it is suggested to increase tetanus toxoid immunization to pregnant mothers, health education for the community and a brief course provided for the traditional birth attendant (TBA) should be enhanced to reduce the incidence and mortality rate of neonatal tetanus.

Co-Authors Adillida Adillida Aileen Clarissa Dauhan Amir S. Madjid, Amir S. Antonius H. Pudjiadi Aridamuriany D Lubis Aridamuriany D Lubis Aridamuriany D. Lubis Aridamuriany Dwiputri Lubis Aridamuriany Dwiputri Lubis Armila Armila Arto, Karina Sugih Austin Simon Tjowanta Ayodhia P. Pasaribu Ayodhia Pitaloka Pasaribu Bambang Supriyatno Beatrix Siregar Beatrix Siregar, Beatrix Bidasari Lubis Bugis Mardina Lubis C. Saragih, Rina Chaerul Yael Chairoel Yoel Chairuddin P. Lubis Chairuddin P. Lubis Chairuddin P. Lubis Chairul Yoel Chairul Yoel Chairul Yoel Chairul Yoel Chairul Yoel Chairul Yoel, Chairul Charles Siregar Charles Siregar Cynthea Prima Destariani Danny Dasraf Dewi Shandi Laila, Dewi Shandi Diana Aulia Dini Lailani Ditho Athos P. Daulay Effa Triani Effa Triani Efori Gea Elmeida Effendy Ema Mutiara Emil Azlin Emil Salim Endang D. Hamid Erika S. Panjaitan Erna Mutiara Erna Mutiara Erna Mutiara Erniwaty P Panggabean Fauzi Rizal Fujiati, Isti Ilmiati Gabriel P. Gema N. Yanni Gema Nazri Yani Gema Nazri Yanni Gema Nazri Yanni Gema Nazri Yanni Gunanti . Hakimi Hakimi Hartono Gunardi Hasibuan, Syahreza Helmi M. Lubis Hendy Zulkarnain Hindra I. Satari, Hindra I. Ichwan HH Batubara Indah Nur Lestari Irene Yuniar, Irene Iskandar Z Lubis Iskandar Z. Lubis Isra Firmansyah Isra Firmansyah Isti Ilmiati Jenny Ginting Johannes H. Saing Johnny Arsyad Jose Rizal Latief Batubara Jose RL Batubara Jufitriani Ismy Jufitriany Ismi Julianti Julianti, Julianti Kristina Ambarita Kristina Ambarita Lestari, Indah Nur Lily Irsa Lily Rahmawati Lubis, Inke Nadia Mahadi Mahadi Manihar D. Marbun Melda Deliana Melda Deliana Melda Deliana Monalisa Elizabeth Muhammad Adib Mahara Muhammad Ali Muhammad Ali Muhammad Ali Nafianti, Selfi Nasution, Badai Buana Nelly Rosdiana Nora Sovira Oke Rina Ramayani Oke Rina Ramayani Oke Rina Ramayani, Oke Rina Purnama Fitri Putri Amelia Putri Amelia Putri Amelia Putri Hasria Sri Murni Rafita Ramayanti Rafita Ramayati Rafita Ramayati Ria Puspitasari Ria Puspitasari Ridwan M. D. Rina A.C. Saragih Rina A.C. Saragih, Rina A.C. Rina Amalia C Saragih Rina Amalia C. Saragih Rina Amalia C. Saragih Rina Amalia Karomina Saragih Rina C. Saragih Rismala Dewi Rizki Aryo Wicaksono Rizki Aryo Wicaksono ROSIHAN ANWAR Rosmayanti Siregar Rosmayanti Siregar, Rosmayanti Rusdidjas dr Rusdidjas Rusdidjas Rusdidjas Rusdidjas Saptawati Bardosono Saragih, Rina Amalia Sembiring, Krisnarta Siregar, Gurnal Rai Gandra Siska Mayasari Siti Helmyati Sri Alemina Ginting Sri Sofyani Srie Yanda Sulaiman Yusuf Suryani Ginting Syafruddin Haris Syahril Pasaribu Syahril Pasaribu Syahril Pasaribu Syahril Pasaribu Syahril Pasaribu Syahril Pasaribu Syahril Pasaribu Syamsidah Lubis Syarif, Erlita Wienanda Syilvia Jiero T. Murad El Fuad Taralan Tambunan Tiangsa Sembiring Tjhin Wiguna Tjut Dharmawati Tri Faranita Tri Faranita Trina Devina Wahyudi Wahyudi Wijaya, Richo Wisman Dalimunte Wisman Dalimunthe Yanni, Gema Nazri Yanni, Gema Nazri Yoyoh Yusroh Yunnie Trisnawati Yunnie Trisnawati Yunnie Trisnawati Yunnie Trisnawati Yunnie Trisnawati Yunnie Trisnawati Yunnie Trisnawati Zakiudin Munasir

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