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All Journal The Indonesian Biomedical Journal Sari Pediatri Paediatrica Indonesiana Majalah Kedokteran Nusantara The Journal Of Medical School Sumatera Medical Journal Cermin Dunia Kedokteran Cermin Dunia Kedokteran
Munar Lubis
Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Sumatera Utara
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Pengaturan cairan pada acute lung injury Monalisa Elizabeth; Munar Lubis; Yunnie Trisnawati
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 1 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Mechanical ventilation is a life-saving technology for patients who develop acute lung injury (ALI) and investigators have conducted numerous investigations to determine the optimal support method and has been used for several decades. The incidence of ALI is quoted to be between 17 and 34 per 100,000 patients for year. Mechanical ventilation is indicated in patients with severe hypoxemia despite oxygen therapy, severe hypercapnia, or excessive work of breathing. Fluid management with the goal to obtain zero fluid balance in ARDS patients without shock or renal failure significantly increases the number of days without mechanical ventilation. Liberal and conservative fluid strategies are therefore complementary and should ideally follow each other in time in the same patient whose hemodynamic state progressively stabilizes.Key words : constipation; functional; children; medical therapy
Rasiotekanan darah terhadap tinggi badan dalam diagnosis hipertensi pada remaja Kristina Ambarita; Oke Rina Ramayani; Munar Lubis; Isti Ilmiati; Rafita Ramayati; Rusdidjas dr
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 2 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Diagnosis of hypertension in children and adolescents according to the Fourth Report from the National High Blood Pressure Education Program (NHBPEP) Working Group on Children and Adolescents 2004 is complicated, influenced by gender, age, and height. This resulted in an effort to find alternative ways to overcome the lack of practical diagnostic tool hypertension in adolescents. Current research is centered on the use of anthropometric variables to detect hypertension in adolescents. Height is a factor that plays an important role in determining blood pressure because of body size affects blood pressure. The blood pressure to height ratio is a simple method that can be used for diagnosing hypertension in adolescents. This ratio is not influenced by age which means determining the cut-off point of hypertension is not according to age specific, and the ratio is not adjusted in height so that this ratio can be used in adolescents who are short or tall. This ratio has a high sensitivity and specificity in the diagnosis of hypertension, which is high capabilities in the detection of hypertension and to determine non hypertension in adolescents.Keyword :adolescence, blood pressure to height ratio, diagnosis, hypertension
Gangguan ginjal akut pada keadaan kritis Putri Amelia; Munar Lubis; Yunnie Trisnawati
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 47, No 2 (2014): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Acute kidney injury is characterized by a reversibe increase in the blood concentration of creatinine an nitrogenous waste products and by the inability of the kidney to regulate fluid and electrolyte homeostasis approprietly. Acute kidney injury is increasingly recognized as a cause of increased morbidity in critically ill children and adults, and affects patient survival. Acute kidney injury is known to be an independent risk factor for mortality, and research pursues optimization of diagnosis, management, and outcome.Key words : acute kidney injury; critical ilness
Peningkatan kadar troponin I sebagai prognostik mortalitas pada anak dengan syok septik Emil Salim; Munar Lubis; Yunnie Trisnawati; Gema N. Yanni; Rina A.C. Saragih; Aridamuriany D. Lubis
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 47, No 2 (2014): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Septic shock remains a major cause of morbidity and mortality in children admitted to pediatric intensive care unit. The incidence of septic shock increased in 30-40 years, with estimate 7% of total deaths in children due to severe sepsis and septic shock. The cardiovascular system is one of the most commonly affected organ in a state of severe sepsis and septic shock. Troponin I is a good marker for assessing the extent of heart muscle damage and elevated levels of troponin I in sepsis patients reflects the severity of the disease, myocardial dysfunction, and poor prognosis. Septic shock patients with impaired cardiac function have an increased risk of mortality 70% to 90% when compared to patients with or without cardiac dysfunction.Keywords : septic shock; troponin I; mortality
Mean Platelet Volume sebagai Faktor Prognostik Sepsis pada Anak Ria Puspitasari; Rina C. Saragih; Munar Lubis
Cermin Dunia Kedokteran Vol 46, No 5 (2019): Pediatri
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i5.483

Abstract

Abstrak. Sepsis adalah kondisi klinis disfungsi organ yang berpotensi mengancam nyawa. Skor Pediatric Logistic Organ Dysfunction 2 (PELOD-2) sering digunakan untuk memprediksi kematian pasien sepsis. Sebagian besar penelitian menemukan peningkatan nilai MPV pada pasien sepsis, baik neonatus maupun dewasa. Nilai MPV dapat dijadikan salah satu parameter untuk menilai prognosis pasien sepsis.Abstract. Sepsis is a clinical condition of organ dysfunction that potentially life-threatening. Pediatric Logistic Organ Dysfunction 2 (PELOD-2) is used to predict mortality in patients with sepsis. Many studies found increased MPV value in sepsis (neonates and adults). MPV can become a prognostic parameter in sepsis. 
Peran Antitrombin III sebagai Penanda Sepsis pada Anak Indah Nur Lestari; Chairul Yoel; Munar Lubis; Rina Amalia C Saragih; Gema Nazri Yanni; Yunnie Trisnawati; Aridamuriany D Lubis; Badai Buana Nasution
Cermin Dunia Kedokteran Vol 50 No 11 (2023): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i11.914

Abstract

Sepsis is a life-threatening organ dysfunction caused by dysregulation of the immune response to infection. Antithrombin III is a single plasma bound glycoprotein and include a class of serine protease (serpine) inhibitors; its synthesis in the liver decreases during sepsis.
Peran Antitrombin III sebagai Penanda Sepsis pada Anak Indah Nur Lestari; Chairul Yoel; Munar Lubis; Rina Amalia C Saragih; Gema Nazri Yanni; Yunnie Trisnawati; Aridamuriany D Lubis; Badai Buana Nasution
Cermin Dunia Kedokteran Vol 50 No 11 (2023): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i11.914

Abstract

Sepsis is a life-threatening organ dysfunction caused by dysregulation of the immune response to infection. Antithrombin III is a single plasma bound glycoprotein and include a class of serine protease (serpine) inhibitors; its synthesis in the liver decreases during sepsis.
Quality of life in episodic hypoxic children after emergency department or PICU hospitalization Yuniar, Irene; Julianti, Julianti; Gunardi, Hartono; Dewi, Rismala; Wiguna, Tjhin; Lubis, Munar
Paediatrica Indonesiana Vol. 65 No. 5 (2025): September 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.5.2025.357-63

Abstract

Background Studies on long–term outcomes of hypoxic children after being hospitalized are limited, even though hypoxia is known to affect their quality of life (QoL). Objective To assess the QoL of children with episodic hypoxia following hospitalization in the emergency department (ED) and Pediatric Intensive Care Unit (PICU). Methods A prospective cohort design study targeting pediatric patients aged 2–7 years with critical illness was conducted at Dr. Cipto Mangunkusumo Hospital. Inclusion criteria are hypoxia patients receiving oxygen therapy, defined from the ratio of partial arterial oxygen pressure and inspired oxygen (PaO2/FiO2). The PedsQLTM questionnaire was used to assess QoL at the time of admission and 3 months after hypoxia event. Patients with cerebral palsy, mental retardation, chromosomal abnormalities, liver transplantation, and length of stay ≤24 hours were excluded. Data distribution in numerical form was analyzed using the Kolmogorov–Smirnov test. Results Forty-six children with a median age of 4 (2–7) years had decreased QoL at 3 months after episodic hypoxia, based on PedsQLTM scores. The physical, emotional, and social domains were significantly decreased (P<0.01) compared to QoL at the time of admission. Prior to admission, 78.3% of children had already experienced impaired QoL. Conclusion Children with episodic hypoxia demonstrated a decline in QoL at 3 months after hypoxia event based on PedsQLTM scores. Specifically, the physical, emotional, and social domains were significantly decreased compared to at the time of admission.  
Co-Authors Adillida Adillida Aileen Clarissa Dauhan Amir S. Madjid, Amir S. Antonius H. Pudjiadi Aridamuriany D Lubis Aridamuriany D Lubis Aridamuriany D. Lubis Aridamuriany Dwiputri Lubis Aridamuriany Dwiputri Lubis Armila Armila Arto, Karina Sugih Austin Simon Tjowanta Ayodhia P. Pasaribu Ayodhia Pitaloka Pasaribu Bambang Supriyatno Beatrix Siregar Beatrix Siregar, Beatrix Bidasari Lubis Bugis Mardina Lubis C. Saragih, Rina Chaerul Yael Chairoel Yoel Chairuddin P. Lubis Chairuddin P. Lubis Chairuddin P. Lubis Chairul Yoel Chairul Yoel Chairul Yoel Chairul Yoel Chairul Yoel Chairul Yoel, Chairul Charles Siregar Charles Siregar Cynthea Prima Destariani Danny Dasraf Dewi Shandi Laila, Dewi Shandi Diana Aulia Dini Lailani Ditho Athos P. Daulay Effa Triani Effa Triani Efori Gea Elizabeth, Monalisa Elmeida Effendy Ema Mutiara Emil Azlin Emil Salim Endang D. Hamid Erika S. Panjaitan Erna Mutiara Erna Mutiara Erna Mutiara Erniwaty P Panggabean Fauzi Rizal Fujiati, Isti Ilmiati Gabriel P. Gema N. Yanni Gema Nazri Yani Gema Nazri Yanni Gema Nazri Yanni Gema Nazri Yanni Gunanti . Hakimi Hakimi Hartono Gunardi Hasibuan, Syahreza Helmi M. Lubis Hendy Zulkarnain Hindra I. Satari, Hindra I. Ichwan HH Batubara Indah Nur Lestari Irene Yuniar, Irene Iskandar Z Lubis Iskandar Z. Lubis Isra Firmansyah Isra Firmansyah Isti Ilmiati Jenny Ginting Johannes H. Saing Johnny Arsyad Jose Rizal Latief Batubara Jose RL Batubara Jufitriani Ismy Jufitriany Ismi Julianti Julianti, Julianti Kristina Ambarita Kristina Ambarita Lestari, Indah Nur Lily Irsa Lily Rahmawati Lubis, Inke Nadia Mahadi Mahadi Manihar D. Marbun Melda Deliana Melda Deliana Melda Deliana Muhammad Adib Mahara Muhammad Ali Muhammad Ali Muhammad Ali Nafianti, Selfi Nasution, Badai Buana Nelly Rosdiana Nora Sovira Oke Rina Ramayani Oke Rina Ramayani Oke Rina Ramayani, Oke Rina Purnama Fitri Putri Amelia Putri Amelia Putri Amelia Putri Hasria Sri Murni Rafita Ramayanti Rafita Ramayati Rafita Ramayati Ria Puspitasari Ria Puspitasari Ridwan M. D. Rina A.C. Saragih Rina A.C. Saragih, Rina A.C. Rina Amalia C Saragih Rina Amalia C. Saragih Rina Amalia C. Saragih Rina Amalia Karomina Saragih Rina C. Saragih Rismala Dewi Rizki Aryo Wicaksono Rizki Aryo Wicaksono ROSIHAN ANWAR Rosmayanti Siregar Rosmayanti Siregar, Rosmayanti Rusdidjas dr Rusdidjas Rusdidjas Rusdidjas Rusdidjas Saptawati Bardosono Saragih, Rina Amalia Sembiring, Krisnarta Siregar, Gurnal Rai Gandra Siska Mayasari Siti Helmyati Sri Alemina Ginting Sri Sofyani Srie Yanda Sulaiman Yusuf Suryani Ginting Syafruddin Haris Syahril Pasaribu Syamsidah Lubis Syarif, Erlita Wienanda Syilvia Jiero T. Murad El Fuad Taralan Tambunan Tiangsa Sembiring Tjhin Wiguna Tjut Dharmawati Tri Faranita Tri Faranita Trina Devina Wahyudi Wahyudi Wijaya, Richo Wisman Dalimunte Wisman Dalimunthe Yanni, Gema Nazri Yanni, Gema Nazri Yoyoh Yusroh Yunnie Trisnawati Yunnie Trisnawati Yunnie Trisnawati Yunnie Trisnawati Yunnie Trisnawati Yunnie Trisnawati Yunnie Trisnawati Zakiudin Munasir