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All Journal Majalah Kedokteran Bandung Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia Jurnal Kartika Kimia Journal of Midwifery and Nursing JFIOnline JCPS (Journal of Current Pharmaceutical Sciences) JITEKGI Jurnal Ilmiah dan Teknologi Kedokteran Gigi ad-Dawaa : Journal of Pharmaceutical Sciences Science Midwifery Jurnal Buana Farma Jurnal Abdimas Kartika Wijayakusuma Journal of Science and Technology Research for Pharmacy Jurnal Farmasi Indonesia Kartika : Jurnal Ilmiah Farmasi Jurnal Kefarmasian Indonesia
Suci Nar Vikasari, Suci Nar
Universitas Jenderal Achmad Yani
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Evaluation of Medication Use in Patients with Gastroesophageal Reflux Disease (GERD) in the Inpatient Unit at a Hospital in Cimahi Syarifuddin, Syarifuddin; Septiani, Vina; Khoirunnisa, Syifa; Kristian, Randi; Vikasari, Suci Nar
Journal of Midwifery and Nursing Vol. 7 No. 1 (2025): January: Health Science
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v7i1.5888

Abstract

Gastroesophageal Reflux Disease (GERD) is a pathological condition characterized by the regurgitation of gastric contents into the esophagus, resulting in symptoms affecting both the esophagus and extra-esophageal regions. The aim of this study is to ascertain the usage pattern and rationality of GERD medication consumption. This study utilizes an observational approach with a descriptive cross-sectional design. The data collection was performed retrospectively by examining the treatment histories of GERD patients documented in the medical records at the Inpatient Installation of Dustira Hospital from January to June 2023. The sample comprised 200 persons who met the inclusion criteria. Research indicated that individuals with GERD were predominantly female, comprising 73.5%, while males constituted approximately 26.5%. The predominant age range was 18-45 years, comprising 63.5%, followed by 46-59 years at 23.5%. 61 patients received a combination of omeprazole and sucralfate as the predominant medication. The analysis showed that 100% of patients utilized the medication with the appropriate indication, 97.5% with accurate drug selection, 100% with precise dosage, 100% with the right method of administration, and 100% with the appropriate administration interval
Exploring the Alpha-Amylase Inhibitory Potential of Roselle Calyx Extracts (Hibiscus sabdariffa L) in n-Hexane and Ethyl Acetate Fractions Wahyuningsih, Sri; Vikasari, Suci Nar; Kusmayadi, Anandita Tiara
Jurnal Kartika Kimia Vol 8 No 1 (2025): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v8i1.899

Abstract

Diabetes mellitus is a metabolic disorder characterized by elevated blood sugar levels, which result from impaired insulin excretion or sensitivity. Among the various medicinal plants utilized by the Indonesian population, roselle (Hibiscus sabdariffa L) stands out as a potential remedy for several diseases including diabetes mellitus. This study aims to assess the inhibitory potential of roselle on α-amylase enzyme activity. The roselle calyx extraction method was performed through multilevel maceration using n-hexane and ethyl acetate solvents. Testing the activity of inhibiting the α-amylase enzyme was carried out in vitro using acarbose as a comparison. The findings revealed that the n-hexane extract of roselle calyx exhibited potent α-amylase enzyme inhibition with an IC50 value of 20.43 µg/mL. Similarly, roselle calyx ethyl acetate extract demonstrated strongl α-amylase enzyme inhibitory activity, characterized by an IC50 value of 10.13 µg/mL. Meanwhile, acarbose exhibited robust α-amylase inhibitory activity, possessing an IC50 value of 4.04 µg/mL. It is worth noting that all these substances displayed α-amylase enzyme inhibitory activity in the very active category, although their efficacy was not equivalent to acarbose.
Acute Antinflammatory Effect of Marsdenia tinctoria Leaf Water Extract in Carragenan-induced Rats Supito, Sarasvati Sekar Ayu; Sutjiatmo, Afifah Bambang; Kusumawardhana, Gelar Taufiq; Vikasari, Suci Nar
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 8 No.1 (2025)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v8i1.52967

Abstract

Introduction: Tarum areuy (Marsdenia tinctoria) is a plant whose efficacy has not been widely explored. Traditionally used for infections and inflammation related disease.. Aims: To determine the anti-inflammatory effect of M. tinctoria leaf water extract on animals induced by carrageenan.Methods: Extract preparation by boiling in water. Animals were divided into groups, namely control, comparison (diclofenac sodium 4.5 mg/kgBW) and M. tinctoria leaf water extract (20, 40, 80 mg/kgBW). Induction of 0.1 mL of 1% carrageenan was given as much as intraplantar and the test preparation was given orally. Inflammatory and inflammatory inhibition percentages were measured every 30 minutes for 240 minutes. The t-test was utilized in data analysis.  Result: All test doses of M. tinctoria leaf water extract was effective to reduce inflammation in comparison to the control (p<0.05). A dose of 20 mg/kgBW was the optimal anti-inflammatory.. Conclusion: M. tinctoria leaf water extract has the potential as an anti-inflammatory.
Tantangan Industri Farmasi Indonesia di Era Pandemik COVID-19 Windyaswari, Ari Sri; Hermanto, Faizal; Vikasari, Suci Nar; Riyanti, Soraya; Syam, Akhirul Kahfi; Febrinella, Catellya
Jurnal Abdimas Kartika Wijayakusuma Vol 1 No 2 (2020): Jurnal Abdimas Kartika Wijayakusuma
Publisher : LPPM Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (522.939 KB) | DOI: 10.26874/jakw.v1i2.74

Abstract

Abstrak: Situasi pandemik COVID-19 di Indonesia mempengaruhi beberapa sektor penting, diantaranya adalah sektor kesehatan. Farmasi sebagai salah satu garda penting di bidang kesehatan mempunyai tugas fungsi pokok untuk menyediakan obat yang aman, berkhasiat dan berkualitas. Industri farmasi merupakan bagian terdepan yang memiliki peranan penting tersebut sekaligus merupakan bagian terdepan yang terkena dampak dari situasi pandemik COVID-19. Tekanan untuk penemuan vaksin/obat baru sebagai antivirus COVID19 hingga produksi vitamin dan produk nutrisi lain sebagai upaya preventif untuk melindungi masyarakat Indonesia dari peningkatan penularan virus COVID-19 di Indonesia menghadapi berbagai kendala. Pembatasan Sosial Berskala Besar (PSBB), kegiatan karantina serta isolasi merupakan salah satu kendala di dalam bidang produksi. Disisi lain, permintaan akan produk obat meningkat tajam. Apoteker industri dan apoteker komunitas bekerja sama untuk memastikan ketersediaan dan efek terapi obat dapat digunakan oleh masyarakat Indonesia. Tujuan dilaksanakannya webinar ini adalah untuk mengubah paradigma permasalahan menjadi suatu tantangan yang harus diselesaikan oleh sejawat apoteker di seluruh Indonesia. Metode webinar dilaksanakan melalui penyampaian materi dan diskusi panel dari platform ZOOM dan youtube. Hasil post test yang dilaksanakan terhadap 1.700 peserta secara garis besar menunjukkan pemahaman dan kepedulian masyarakat dalam mengatasi berbagai permasalahan di bidang farmasi industry Indonesia. Kata kunci: Apoteker, Industri Farmasi, COVID-19.
ANALISIS FAKTOR RESIKO PENYEBAB PELAYANAN ANTIBIOTIK TANPA RESEP DOKTER DI APOTEK: A REVIEW Tupak, Helma Malini Marol; Vikasari, Suci Nar
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1514

Abstract

The dispensing of antibiotics without a doctor’s prescription in pharmacies remains a common practice and contributes significantly to the rise of antibiotic resistance, which poses a major threat to public health. This phenomenon is driven by interrelated risk factors, including easy access, limited public knowledge, socioeconomic influences, and weak regulatory enforcement. This study aims to identify the risk factors underlying the dispensing of antibiotics without prescriptions in pharmacies. A literature review was conducted by collecting and analyzing Indonesian and English journal articles published between 2015 and 2025. Data were retrieved from Google Scholar and PubMed using keywords related to the sale and purchase of antibiotics without a doctor’s prescription. The findings were analyzed narratively and grouped into three perspectives: business actors, patients or consumers, and regulators. From the perspective of business actors, the risk factors include pharmacy staff attitudes that facilitate non-prescription antibiotic sales, financial motivations, consumer pressure and demand, and insufficient professional knowledge. From the perspective of patients, risk factors involve the ease of obtaining antibiotics without a prescription, economic, social, and cultural influences, lack of awareness and understanding, and prior personal experiences of antibiotic use. From the perspective of regulators, weak supervision and poor law enforcement remain key drivers of this practice. In conclusion, comprehensive efforts are required to address this issue. These include strengthening regulations, improving public education, and enhancing the training of pharmacy personnel. Such interventions are critical to preventing antibiotic misuse and mitigating the long-term consequences of antibiotic resistance on public health.
Co-Authors Afifah B. Sutjiatmo Afifah B. Sutjiatmo Afifah B. Sutjiatmo Afifah Bambang Sutjiatmo Afifah Bambang Sutjiatmo, Afifah Bambang Aisyah, Salmanda Akhirul Kahfi Syam Andi Supriatna Andri R. Rahmadi Andri Reza Rahmadi Anna Choirunnisa Anna Choirunnisa, Anna Ari Sri Windyaswari, Ari Sri Asri Wulandari Astuti, Niken Juni Ayu Nurfitiria Rahmi Ayu Nurfitiria Rahmi, Ayu Nurfitiria Bintussolihah, Falna Candra Candra Candra candra Dewi Lidya Ichwana Nasution Dwi Yuliana Prasita Dzikrial Sa’id Elin Yulinah Sukandar Elin Yulinah Sukandar ELIN YULINAH SUKANDAR Elivas Simatupang Elivas Simatupang Encep Abdurahman Faizal Hermanto Febrinella, Catellya Fikri Alatas Grace S. Mardiana Haq, Fahmy Ahsanul Hartyana Sutarna, Titta Ita Nur Anisa Ita Nur Anisa Khansa Rana Khalifa Kristian, Randi Kuatrina, Kuatrina Kusmaningati, Suswini Kusmayadi, Anandita Tiara Kusumawardhana, Gelar Taufiq Lucky Rachmawan Lucky Rachmawan Melani, Beta Nengdiana Permana Novia Anggraeni Hanafi Novia Anggraeni Hanafi, Novia Anggraeni Oskar Skarayadi, Oskar Pudjiastuti Kartidjo Pudjiastuti Kartidjo Puput Ayu Perdana, Puput Ayu Purwoko, Agus Rachmawan, Lucky Rahajeng, Dea Julianti Redya Hernawati Redya Hernawati, Redya Regita Ayu Lestari Ririn Puspadewi Ririn Puspadewi, Ririn Ririn Sinaga Ririn Sinaga, Ririn RR. Ella Evrita Hestiandari Setiani, Nur Asni Sheba, Shiane Hanako Shifa A. Savitri Siftiani, Nindy Dwi Simatupang, Elivas Solihah, Puspa Sari Dewi Soraya Riyanti, Soraya Sri Wahyuningsih Sujiatmo, Afifah Bambang Sulaeman Al Jati Supito, Sarasvati Sekar Ayu Suryani Suryani Syarifuddin Syarifuddin Syarifuddin Syarifuddin Syifa Khoirunnisa, Syifa Tupak, Helma Malini Marol Vina Septiani, Vina Wita Anggraeni Wulan Anggraeni Yulia Ratnawati, Yulia Yulianti, Maulidya Yuliartati, Ni Luh Ade