Article Per Year (5 Year)
p-Index From 2021 - 2026
4.064
P-Index
This Author published in this journals
All Journal JURNAL KIMIA SAINS DAN APLIKASI Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Alchemy : Journal of Chemistry Jurnal Pengabdian Kepada Masyarakat Sakai Sambayan CHEMPUBLISH JOURNAL Indonesia Chimica Acta Al-Kimia Jurnal SOLMA Walisongo Journal of Chemistry Indonesian Journal of Chemical Analysis (IJCA) Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Jurnal Jejaring Matematika dan Sains Jurnal ABDINUS : Jurnal Pengabdian Nusantara Stannum : Jurnal Sains dan Terapan Kimia Jurnal Sains dan Edukasi Sains SPIN: Jurnal Kimia & Pendidikan Kimia Jurnal Bakti Untuk Negeri Nanggroe: Journal Of Scholarly Service Nanggroe: Journal of Scholarly Service Rafflesia Journal of Natural and Applied Sciences (RJNAS) Jurnal Sains Materi Indonesia Bohr: Jurnal Cendekia Kimia NAWASENA: Journal of Community Service
Mokhamat Ariefin
Department Of Chemistry, Faculty Of Mathematic And Science, University Of Palangka Raya
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

Published : 32 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 32 Documents
Search

 1   2   3   4 
Theoretical Study of Metal Ion Impact on Geometry and Bond Vibrational Properties of Salophen Compound Manurung, Tety Wahyuningsih; Afthoni, Muhammad Hilmi; Steven , Kur Yehezkiel; Pasaribu, Marvin Horale; Ariefin, Mokhamat; Alfanaar, Rokiy
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 17, No 1: June 2024
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70561/ica.v17i1.31808

Abstract

Coordination compounds are compounds consisting of a metal atom as a center surrounded by ligands, which are important in applications such as catalysts and pharmacological sensors. Salophen, as one of the organic ligands, is capable of forming complexes with various metal ions. This study uses a computational chemistry approach to model the geometry, electronic properties, and bond vibrations of compound complexes between salophen and Zn(II), Cd(II), and Hg(II) metal ions using the PM6 semiempirical method. Modeling results show that the metal ion radius affects the dihedral angle of salophen, with the largest angle occurring in the complex with Hg(II) ions, while the complex with Cd(II) ions tends to be close to planar. FTIR analysis shows that the vibrational pattern is influenced by the bond length of salophen with metal ions. In addition, the HOMO-LUMO gap energy of the three complexes is also slightly different, with the Zn-salophen complex having the smallest Egap of 0.25709 eV.
INHIBITION MECHANISM OF COMPONENT EXTRACT OF BAWANG DAYAK ON DIABETES VIA MOLECULAR DOCKING STUDY Ariefin, Mokhamat; Kalalinggi, Septaria Yolan
SPIN JURNAL KIMIA & PENDIDIKAN KIMIA Vol. 5 No. 2 (2023): Juli - Desember 2023
Publisher : UIN Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20414/spin.v5i2.8641

Abstract

Several compounds found within Bawang Dayak, including eleutherine and eleutherol, hold promise as potential therapeutic agentsThis research involved molecular docking and Lipinski rule analysis of 13 ligands derived from flavonoids extracted from bawang dayak. The control ligand, acarbose, was found to form four hydrogen bonds with key amino acids (Gln279, Lys156, Asp242, and Glu411), resulting in a binding energy of -9.8 kcal mol-1. Among the ligands, Ligand 3 displayed a lower binding energy of -9.9 kcal mol-1 compared to acarbose and satisfied all five criteria of Lipinski's rule, despite not forming hydrogen bonds. Instead, Ligand 3 exhibited similar hydrophobic interactions as acarbose with amino acids such as Tyr158, Phe178, Val216, Ser240, Asp242, Glu277, Gln279, His280, Arg315, Asp352, Glu411, and Arg442. Several other ligands exhibited binding energies slightly higher than acarbose, such as Ligands 4, 5, and 8, with binding energies of -8.5 kcal mol-1, -8.6 kcal mol-1, and -8.6 kcal mol-1, respectively. Based on this study, Ligands 3, 4, 5, and 8 are considered potential candidates for anti-diabetic agents. These ligands demonstrated binding energies comparable to acarbose, met at least three of the five Lipinski rule criteria, and exhibited similar amino acid interactions with acarbose, indicating their potential effectiveness in managing diabetes.
Pemodelan Molekul untuk Pengaplikasian Senyawa Anti-UV dari Senyawa Kuersetin Menggunakan Pendekatan Semi Empiris Lidya Tesalonika; Manurung, Tety Wahyuningsih; Mokhamat Ariefin
Jurnal Sains dan Edukasi Sains Vol. 7 No. 2 (2024): Jurnal Sains dan Edukasi Sains
Publisher : Faculty of Science and Mathematics, Universitas Kristen Satya Wacana, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24246/juses.v7i2p128-135

Abstract

Sinar UV merupakan salah satu gelombang elektromagnetik yang dipancarkan oleh matahari. Paparan sinar ultraviolet berlebih dapat menyebabkan dampak buruk bagi kulit, terlebih UV A dan UV B yang memiliki kecenderungan lebih tinggi untuk menyebabkan kerusakan pada kulit. Kuersetin merupakan salah satu senyawa golongan flavonoid yang dapat mengalami modifikasi pada struktur cincin benzenanya membentuk beberapa senyawa turunan kuersetin. Modifikasi struktur cincin benzena kuersetin memberikan pengaruh pada kemampuan kuersetin dalam menyerap sinar UV. Pada penelitian ini dilakukan permodelan struktur dan spektra UV pada tiga senyawa turunan kuersetin melalui metode semi empiris untuk mengetahui sifat dan efektivitas turunan kuersetin sebagai senyawa pelindung radiasi ultraviolet (UV). Studi komputasi yang dilakukan menggunakan Austin Model 1 (AM1) yang dapat memprediksi absorbtivitas UV pada senyawa. Hasil penelitian yang telah dilakukan menunjukkan bahwa modifikasi senyawa kuersetin dengan gugus alkil (metil) pada senyawa 1, 2, dan 3 berpengaruh terhadap panjang ikatan, sudut dehedral, dan energi gap HOMO LUMO 3 senyawa turunan kuersetin tersebut. Data spektrum UV yang dihasilkan melalui pemodelan transisi elektron menunjukkan bahwa ketiga senyawa turunan kuersetin memiliki puncak absorpsi yang terletak pada wilayah UV-A. Ketiga senyawa turunan kuersetin tersebut memiliki potensi sebagai pelindung dari sinar UV-A.
Phytochemical Analysis and Study of Molecular Docking of Leucaena leucocephala Leave Extract as Anticancer Mokhamat Ariefin; Syarpin syarpin; Bibit Harianto
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 1 (2024): April 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i1.4387

Abstract

Cancer is a disease caused by unnatural cell growth in the body. It has become a disease with a high mortality rate in the world. Several therapies have been developed for cancer treatment, one of which is the exploration of the bioactivity of compounds contained in potentially medicinal plants. One of the potential medicinal plants that grows in Central Kalimantan province is L. leucocephala. In this study, the potential of L. leucocephala leaf extract was explored through phytochemical tests and molecular docking approaches. Based on the phytochemical test, it was found that L. leucocephala leaf extract contains flavonoids, terpenoids, and steroids. Based on the test results, a literature study was conducted on the flavonoids and terpenoids content in L. leucocepala leaf extract and molecular docking studies were conducted. Seven dominant compounds of L. leucocephala consisting of flavonoids and terpenoids were tested for their potential as inhibitors of receptor tyrosine kinase. The molecular docking results showed that flavonoid ligands (1-6) had more negative binding affinity values compared to the drug sunitinib, a common drug for cancer therapy, while terpenoid ligand (7) had less favorable binding energy. Based on the Lipinski rule of five test, ligands 1, 2, 4, and 5 fulfill all the criteria given as drug candidates, while ligands 3, 6, and 7 only fulfill 3 out of 5 criteria. Based on Lipinski rule of five and molecular docking, ligand 1,2,4, and 5 has potential to be anticancer.
Pemanfaatan Limbah dan Sumber Daya Lokal dalam Pelatihan Pembuatan Pakan Ikan Mandiri untuk Kelompok KUPS Perikanan Desa Tuwung Pasaribu, Marvin Horale; Ariefin, Mokhamat; Ompusunggu, Dicky Perwira; Saputra, Rızkı Rachmad; Agnestisia, Retno; Yuliana, Yuliana; Purba, Abed Nego; Prianus, Okta
Jurnal ABDINUS : Jurnal Pengabdian Nusantara Vol 9 No 1 (2025): Volume 9 Nomor 1 Tahun 2025
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/ja.v9i1.23684

Abstract

Tuwung Village, Pulang Pisau Regency, possesses significant potential in the fisheries sector. However, the development of this sector is hindered by the reliance on expensive commercial fish feed, which limits profit margins from fish sales. Furthermore, organic waste generated from agricultural and livestock activities remains underutilized, posing a potential environmental pollution problem. To address these challenges, a training program on independent fish feed production utilizing organic waste and local resources has been implemented. This program aims to equip the KUPS Fisheries Group in Tuwung Village with the knowledge and skills to produce high-quality fish feed at a more affordable cost. Through this training, participants were introduced to the concept of utilizing household vegetable waste and motan fish from Lake Sabuah as alternative feed ingredients. Additionally, they received training in both conventional and mechanical fish feed production processes, employing a specially designed mixer unit. The program outcomes indicate that participants successfully grasped the concept of waste and local resource utilization and are now capable of producing fish feed independently. It is anticipated that this program will enhance the productivity and efficiency of fish farming businesses in Tuwung Village, while simultaneously mitigating the environmental impact of organic waste.
Advancements in NMR and IR Spectroscopy: Enhancing Metabolomics and Disease Diagnostics in the Health Sector: A Comprehensive Review Saputra, Rizki Rachmad; Ariefin, Mokhamat; Kumalasari, Meiyanti Ratna; Dongoran, Junita; Tampubolon, Mulani Jeni Lestari; Sulistiawati, Putri; Simangunsong, Sri Yulandari; Ariska, Risya; Paksi, Pandu Gizta Rapi; Siska, Amelia; Yanti, Jeddah; Maknun, Luluil
Indonesian Journal of Chemical Analysis (IJCA) Vol. 7 No. 2 (2024): Indonesian Journal of Chemical Analysis
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/ijca.vol7.iss2.art6

Abstract

Metabolomics has emerged as a critical field in understanding biological processes and disease mechanisms, necessitating advancements in analytical techniques to handle complex biological samples. This review explores the global landscape of metabolomics, with a focus on the use of spectroscopy and spectrometry. Techniques such as UV-Vis and Fourier Transform InfraRed (FTIR) spectroscopy offer fast and cost-effective metabolite tracing but are limited by their sensitivity, particularly for low-abundance metabolites. Nuclear Magnetic Resonance (NMR) spectroscopy, despite being less sensitive than mass spectrometry (MS), provides unparalleled structural information, distinguishing metabolites with similar mass-to-charge ratios. NMR's capability to detect metabolites in the 1-10 µM range highlights its effectiveness in metabolomics. This review categorizes advancements in these techniques, starting with global contributions to spectroscopy, followed by detailed discussions on FTIR strategies for metabolite tracing, and concluding with NMR's qualitative and quantitative applications in metabolomics and disease diagnostics. The review underscores the continuous development in sample preparation and data integration, enhancing the accuracy and applicability of these techniques, positioning NMR and FTIR as essential tools in modern metabolomic research.
Aplikasi Instrumen Spektroskopi FTIR dan Spektrometri Massa di Dunia Kesehatan: Review Rizki Rachmad Saputra; Mokhamat Ariefin; Esintia Kristia; Bela D; Dominikus Diki Wahyudi; Ansori Rahman; Ni Wayan Prema Mulya Sari; Ayu Puspita Sari; Siti Misbah Aisah
Bohr: Jurnal Cendekia Kimia Vol 2 No 01 (2023): Bohr: Jurnal Cendekia Kimia Vol 02 No 01
Publisher : Program Studi Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kesehatan adalah suatu hal penting dari sebuah kehidupan seorang manusia. Kualitas pelayanan kesehatan merupakan tingkat keunggulan pelayanan kesehatan yang dapat memenuhi kebutuhan pasien. Salah satu pelayanan penunjang kesehatan pasien. Ilmu kedokteran saat ini mulai canggih, mulai dengan cara herbal atau dengan cara medis. Namun seiring dengan kebutuhan penyakit manusia makin lama makin tidak menentu jenis penyakit, maka dari itu dokter pun banyak yang memulai mempelajari banyak cara pengobatan. Salah satu pengobatan atau pendekteksi penyakit yang banyak di teliti dengan cara instrumen. Oleh karena itu, Pada penelitian ini kami mereview Aplikasi Instrumen Spektroskopi FTIR dan Spektrometri Massa di Dunia Kesehatan.
Coaching on Fabrication of Natural pH Indicators as an Alternate Synthetic Indicators at SMK Muhammadiyah Palangka Raya: Pelatihan Pembuatan Indikator pH Alami sebagai pengganti Indikator Sintetis di SMK Muhammadiyah Palangka Raya Noverda Ayuchecaria; Mokhamat Ariefin; Yuliana; Ansori Rahman; Ni Wayan Prema Mulyasari
NAWASENA : JOURNAL OF COMMUNITY SERVICE Vol. 1 No. 01 (2023): Vol 01 No 01 2023
Publisher : NAWASENA : JOURNAL OF COMMUNITY SERVICE

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstrak SMK Kesehatan Muhammadiah merupakan sekolah farmasi yang didirikan pada maret 2017 dan mulai menerima siswa awal tahun pelajaran 2017/ 2018. Sebagai sekolah baru, SMK Kesehatan Muhammadiyah telah terakreditasi oleh Badan Akreditasi Nasional (BAN) pada 2019. Materi asam basa menjadi pilar penting dalam titrasi yang sering ditemui dalam bidang kefarmasian. Namun, kurangnya sumber belajar terutama prasarana menyebabkan praktikum di sekolah tidak terlaksana. Kendala praktikum yang sering dialami yaitu keterbatasan indikator kimia karena harganya mahal. Tujuan pengabdian ini adalah memberikan alternatif indikator asam-basa alami dari ekstrak bahan alam sebagai pengganti indikator kimia. Selain harganya lebih murah, bahan alam mudah diolah dan jumlanya melimpah. Beberapa jenis bunga seperti bunga sepatu, asoka merah, bougenville (bunga kertas) merah, bunga kencana ungu, dan kunyit diekstrak dengan etanol, selanjunya kertas saring seukuran kertas lakmus dimaserasi ke dalam ekstrak tersebut. Setelah kering dapat disimpan dan digunakan langsung untuk penguijian larutan asam – basa. Kegiatan pengabdian ini diikuti oleh 22 siswa pada tanggal 26 Januari 2023 di ruang aula SMK Kesehatan Muhammadiah. Kegiatan pengabdian yang diberikan berupa pemaparan indikator dan pembuatan, ciri bahan sebagai indikator alami, demontrasi dan pembimbingan pembuatan indikator alami. Hasil kuesioner menunjukkan tingkat pemahaman peserta dalam kategori baik (76,5 %). Kegiatan ini memberi tambahan pengetahuan bagi siswa dalam pemanfaatan bahan alam sebagai pengganti indikator sintetik. Abstract SMK Kesehatan Muhammadiah is a pharmacy school that was founded in March 2017 and began accepting students at the beginning of the 2017/2018 academic year. As a new school, SMK Kesehatan Muhammadiyah has been accredited by the National Accreditation Board (BAN) in 2019. Acid-base matter is an important pillar in titration that is often found in the pharmaceutical field. However, the lack of learning resources, especially infrastructure, caused practicum in schools to not be carried out. The practicum obstacle that is often experienced is the limitation of chemical indicators because they are expensive. Several types of flowers such as shoe flowers, red asoka, red bougenville (paper flowers), purple datea flowers, and turmeric are extracted with ethanol, and then filter paper the size of litmus paper is macerated into the extract. After drying, it can be stored and used directly for the presentation of acid-base solutions. This service activity was attended by 22 students on January 26,2023 in the hall room of SMK Kesehatan Muhammadiah. The service activities provided are in the form of exposure to indicators and manufacture, characteristics of materials as natural indicators, demonstration, and guidance on making natural indicators. The results of the questionnaire showed the level of understanding of participants in the good category (76.5 %). This activity provides additional knowledge for students in the use of natural materials as a substitute for synthetic indicators.
Synthesis and Optical Properties of Carbon Quantum Dots Based on Terung Dayak (Solanum Ferox) Fruit Juice as Antioxidant and Metal Ion Sensor Ariefin, Mokhamat; Pasaribu, Marvin Horale; Manurung, Tety Wahyuningsih; Hakim, Muh. Supwatul; Iftitah, Elvina Dhiaul; Suma, Joy Angel Aria; Cahyani, Risfiah Ruli
Jurnal Kimia Sains dan Aplikasi Vol 28, No 4 (2025): Volume 28 Issue 4 Year 2025
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.28.4.176-182

Abstract

Carbon dots (CDs) are a novel class of carbon-based nanomaterials with diverse applications due to their biocompatibility, optical properties, and chemical stability. This study aims to synthesize CDs from Terung Dayak (Solanum ferox) using a microwave-assisted method and evaluate their optical properties, metal ion sensing capability, and antioxidant activity. The CDs were synthesized with variations in microwave power and citric acid concentration, specifically: CD-a using 1 g citric acid at 600 W, CD-b using 2 g citric acid at 600 W, CD-c using 3 g citric acid at 600 W, and CD-d using 2 g citric acid at 800 W, and then characterized using UV-Vis and fluorescence spectroscopy. The results revealed strong UV absorption with maximum peaks at 250 nm for all CDs synthesized and 275 nm for CD-d, depending on synthesis conditions. The CDs exhibited fluorescence intensity influenced by microwave power, with the highest intensity observed for CDs synthesized at 800 W and 2 g of citric acid. The optical bandgap from UV-Vis spectra, determined via Tauc plot analysis, ranged from 4.03 eV to 4.71 eV, indicating quantum confinement effects for all CDs. Furthermore, CD-d demonstrated selective fluorescence quenching for Fe3+ ions, which quenched the fluorescence of the CD. Antioxidant activity was confirmed via 2,2-diphenyl-1-picryhydrazyl (DPPH) radical scavenging, with an IC50 value of 126 ppm for CD-d. These findings highlight the potential of Terung Dayak-derived CDs as multifunctional materials for sensing and antioxidant applications.
Pembinaan Persiapan Olimpiade Bidang Kimia pada Siswai SMA Negeri 5 Palangka Raya Manurung, Tety Wahyuningsih; Pasaribu, Marvin Horale; Alfanaar, Rokiy; Rosmainar, Lilis; Ariefin, Mokhamat
NAWASENA : JOURNAL OF COMMUNITY SERVICE Vol. 3 No. 01 (2025): Vol. 3 No. 01 2025
Publisher : NAWASENA : JOURNAL OF COMMUNITY SERVICE

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan kesiapan siswa dalam menghadapi Olimpiade Sains Nasional (OSN) bidang Kimia melalui program pendampingan dan pembinaan di SMAN 5 Palangka Raya. Metode yang digunakan mencakup beberapa tahapan, yaitu persiapan, pre-test, pembinaan materi, latihan soal, post-test, dan evaluasi. Program ini diikuti oleh siswa yang telah diseleksi berdasarkan minat dan kemampuan akademik mereka dalam bidang Kimia. Evaluasi dilakukan dengan membandingkan hasil pre-test dan post-test guna mengukur efektivitas pendampingan yang diberikan. Hasil kegiatan menunjukkan adanya peningkatan pemahaman dan keterampilan siswa dalam menyelesaikan soal-soal OSN Kimia, yang mengindikasikan bahwa metode pembinaan yang diterapkan cukup efektif. Selain itu, kegiatan ini juga berdampak positif bagi guru pendamping dalam mengembangkan strategi pembelajaran yang lebih sistematis dan berbasis kompetisi. Dengan adanya program ini, diharapkan pembinaan OSN Kimia di sekolah dapat dilakukan secara lebih terstruktur dan berkelanjutan guna meningkatkan prestasi akademik siswa di tingkat yang lebih tinggi.
Co-Authors Alfanaar, Rokiy Ansori Rahman Ariska, Risya Ayu Puspita Sari Ayuchecaria, Noverda Bela D Bibit Harianto Cahyani, Risfiah Cahyani, Risfiah Ruli Dicky Perwira Ompusunggu Dominikus Diki Wahyudi Dongoran, Junita Efriyana oksal Elvina Dhiaul Iftitah Esintia Kristia Fatchiyatun Ni’mah Febriana Kesuma, Ruth Hakim, Muh. Supwatul Harianto, Bibit Hermayantiningsih, Dwi Hermayatiningsih, Dwi Horale Pasaribu, Marvin Isaura Silalahi, Anastasya Jeddah Yanti Kalalinggi, Septaria Yolan Komara, Nisa Kartika Krissilvio, Eka Jhonatan Lidya Tesalonika Lilis Rosmainar Maknun, Luluil Marvin Horale Pasaribu Muhammad Hilmi Afthoni Nababan, Jessicca Nainggolan, Yuni Natania Gracia, Amanda Ni Wayan Prema Mulya Sari Ni Wayan Prema Mulyasari Ni'mah, Fatchiyatun Oksal, Efriyana Paksi, Pandu Gizta Rapi Pramudita, Dimas Prianus, Okta Purba, Abed Nego Rahmi Wulandari, Oktavia Remi Ayu Pratika Retno Agnestisia Risfa Aliya Al-Hadi Rizki Rachmad Saputra Roil Bilad, Muhammad Ryu Pratiwi, Djihan Sari, Meiyanti Ratna Kumala Simangunsong, Sri Yulandari Simbolon, Wenika Siska, Amelia Siti Misbah Aisah Steven , Kur Yehezkiel Sugiani, Tina Sulistiawati, Putri Suma, Joy Angel Aria Syarpin syarpin syarpin, syarpin Tampubolon, Mulani Jeni Lestari Tety Wahyuningsih Manurung Titik Andriani, Titik Utami Irawati Vety Sri Harlinda Ayudha Wahyuningsih Manurung, Tety Yolan Kalalilinggi, Septaria Yuliana Yuneta Yuyun Yuniarti, Yuyun