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Modelling of Flavanoid Derivatives from Leucaena leucocephala as Anti-UV Alfanaar, Rokiy; Manurung, Tety Wahyuningsih; Ariefin, Mokhamat
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 1 (2024): April 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i1.4396

Abstract

While UV light has benefits for life, excessive exposure to UV light also has negative effects on humans. Examples of the negative effects of UV exposure include cancer. Therefore, the exploration for materials that can be used as anti-UV continues to grow. One of them is extract from Leucaena leucocephala leaves. To study the potential of a compound as anti-UV, one method can use a molecular modeling approach using the semi-empirical method. Based on this, 8 flavone-derived compounds contained in L. leucocephala leaf extract were modeled with a semi-empirical approach using the PM3 method, and electronic-transition was calculated using ZINDO/S. The geometry optimization results showed that the bond length between carbon atoms in flavonoid tururnans did not change significantly with the difference in functional groups. However, there is a significant difference in the dihedral angle of the compound due to the repulsion of functional groups. The results of the electronic transition calculation showed that all flavonoid derivatives 1-8 are active in the UV A, UV B, and UV C regions. So it can be said that flavones 1-8 have potential as anti-UV. In addition, the energy level of HOMO-LUMO compounds was also calculated. Flavonoid 1 has the smallest Eg while flavonoid 8 has the largest Eg
Review: Inovasi Membran Terinkorporasi dengan Enzim Lakase: Solusi Efisien dan Ramah Lingkungan dalam Pengolahan Air Krissilvio, Eka Jhonatan; Pasaribu, Marvin Horale; Ariefin, Mokhamat; Manurung, Tety Wahyuningsih
Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Vol 26, No 2 (2025): CHEMICA
Publisher : Jurusan Kimia FMIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/chemica.v26i2.71230

Abstract

Air adalah sumber daya alam yang dibutuhkan untuk kelangsungan metabolisme manusia dan semua makhluk hidup. Keberadaan polutan dalam air, seperti zat warna dari industri tekstil telah menjadi masalah serius yang mengancam lingkungan dan kesehatan manusia. Pentingnya menjaga keberlanjutan sumber daya alam, terutama air, telah memicu penelitian dalam mengatasi pencemaran air oleh polutan seperti zat warna dari industri tekstil. Dalam konteks ini, teknologi enzim terinkorporasi dalam membran muncul sebagai solusi inovatif. Membran enzim menggabungkan efisiensi teknologi membran dalam pemisahan molekul mikro dengan kemampuan enzim mengoksidasi senyawa organik kompleks, termasuk zat warna. Lakase, sebuah enzim multitembaga yang umumnya ditemukan pada tumbuhan, serangga, dan jamur, telah digunakan untuk mengurai zat warna sulit dihilangkan. Penggunaan membran terinkorporasi dengan enzim lakase telah membawa terobosan signifikan dalam sistem filtrasi air. Lakase tidak hanya efisien dalam memisahkan zat warna, tetapi juga ramah lingkungan karena menggunakan reaksi biokimia alami tanpa bahan kimia tambahan yang merusak ekosistem air.