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All Journal JURNAL KIMIA SAINS DAN APLIKASI Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Alchemy : Journal of Chemistry Jurnal Pengabdian Kepada Masyarakat Sakai Sambayan CHEMPUBLISH JOURNAL Indonesia Chimica Acta Al-Kimia Jurnal SOLMA CHEESA: Chemical Engineering Research Articles Walisongo Journal of Chemistry Indonesian Journal of Chemical Analysis (IJCA) Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Jurnal Jejaring Matematika dan Sains Jurnal ABDINUS : Jurnal Pengabdian Nusantara Stannum : Jurnal Sains dan Terapan Kimia Jurnal Sains dan Edukasi Sains SPIN: Jurnal Kimia & Pendidikan Kimia Jurnal Bakti Untuk Negeri Nanggroe: Journal Of Scholarly Service Nanggroe: Journal of Scholarly Service Rafflesia Journal of Natural and Applied Sciences (RJNAS) Jurnal Sains Materi Indonesia Bohr: Jurnal Cendekia Kimia NAWASENA: Journal of Community Service
Mokhamat Ariefin
Department Of Chemistry, Faculty Of Mathematic And Science, University Of Palangka Raya
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Peningkatan Kemandirian Kesehatan Masyarakat melalui Produksi Herbal Berbasis Tanaman TOGA Kearifan Lokal oleh Ibu-Ibu PKK Desa Bahu Palawa Pasaribu, Marvin Horale; Manurung, Tety Wahyuningsih; Surbakti, Ranintha Br.; Ariefin, Mokhamat; Oktaviani, Revalina; Syaputra, Noor Angga
Jurnal SOLMA Vol. 15 No. 1 (2026)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v15i1.20875

Abstract

Background: Pemanfaatan Tanaman Obat Keluarga (TOGA) sebagai bahan baku jamu tradisional berpotensi meningkatkan derajat kesehatan sekaligus membuka peluang ekonomi bagi masyarakat desa. Namun, keterbatasan pengetahuan dan keterampilan ibu-ibu PKK di Desa Bahu Palawa dalam mengolah TOGA menyebabkan pemanfaatannya belum optimal. Kegiatan pengabdian masyarakat ini bertujuan meningkatkan kemampuan peserta dalam memproduksi jamu serbuk jahe dan berbagai variasi wedang seduh berbasis kearifan lokal. Metode: Program dilaksanakan melalui tahapan sosialisasi, pelatihan, praktik demonstrasi, serta evaluasi pengetahuan dengan pre-test dan post-test, dilengkapi dengan uji organoleptik produk. Peserta dilatih mulai dari persiapan bahan, teknik pengeringan menggunakan oven dryer, formulasi komposisi bahan, hingga pengemasan produk akhir. Hasil: Evaluasi menunjukkan peningkatan signifikan pemahaman peserta, dengan nilai rata-rata pre-test 32,3% meningkat menjadi 91,0% pada post-test. Uji organoleptik juga memperlihatkan penerimaan yang tinggi, di mana 80–90% responden menyatakan suka hingga sangat suka terhadap warna, rasa, dan aroma produk jamu yang dihasilkan. Produk utama berupa jamu serbuk jahe, wedang hangat menyegarkan, wedang rempah pahit manis, dan wedang siru biru dinilai memiliki manfaat kesehatan yang relevan, seperti menjaga daya tahan tubuh, membantu pencernaan, dan mendukung kesehatan jantung. Kesimpulan: Kegiatan ini berhasil meningkatkan pengetahuan dan keterampilan ibu-ibu PKK dalam mengolah TOGA menjadi produk herbal bernilai tambah. Selain berkontribusi pada kemandirian kesehatan keluarga, program ini juga membuka peluang usaha desa berbasis kearifan lokal yang berkelanjutan.
DFT-Based Molecular Analysis of Imidazole Derivatives as Additives to Enhance Ionic Conductivity in Polymer Electrolyte Membranes Marvin Pasaribu; Mokhamat Ariefin; Sun Theo Constan Lotebulo Ndruru; Ferdinand Hidayat; Multazam
CHEESA: Chemical Engineering Research Articles Vol. 8 No. 1 (2025)
Publisher : Universitas PGRI Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/cheesa.v8i1.22136.13-22

Abstract

The demand for efficient and stable lithium-ion batteries has driven research on advanced polymer electrolyte membranes (PEM) with improved ionic conductivity. This study investigated imidazole and its derivatives as additives in PEM to enhance battery performance. Using Density Functional Theory (DFT) with the def2-TZVP basis set, key quantum parameters such as HOMO-LUMO energies, energy gap (?Egap), electronegativity (?), softness (?), electron transfer fraction (?N), and net electrophilicity (??) were analyzed. Results showed that imidazole derivatives with electron-withdrawing groups, like acrylate and tosyl, had lower ELUMO and smaller ?Egap, improving lithium ion (Li?) interactions and mobility within the polymer matrix. Additionally, compounds with high ? and ?, such as BTIM and BZIM, enhanced ion stabilization and transport, leading to better electrolyte performance. Thus, modifying imidazole structures through specific substitutions is a promising approach to optimize PEM, supporting the development of more efficient and stable lithium-ion batteries.
SPECTROSCOPIC CHARACTERIZATION AND UV-PROTECTIVE POTENTIAL OF ARCANGELISIA FLAVA EXTRACT Tety Wahyuningsih Manurung; Rokiy Alfanaar; Mokhamat Ariefin; Marvin Horale Pasaribu; Eva Susanty Simaremare
Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Vol. 7 No. 2 (2025): Literasi Artikel Penelitian Kimia
Publisher : Program Studi Kimia, Fakultas MIPA, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/jc.v7i2.5712

Abstract

The increasing demand for natural UV-protective agents has led to the exploration of plant-based bioactive compounds. Yellow root (Arcangelisia flava) extract is traditionally used in medicine and contains flavonoids, alkaloids, and terpenoids with potential photoprotective properties. This study aimed to characterize the chemical composition of A. flava extract and evaluate its UV-absorbing properties using UV-Vis and FTIR spectroscopy. The extract was obtained through maceration with ethanol, followed by spectroscopic analysis. The UV-Vis spectrum (200–400 nm) revealed multiple absorption peaks, particularly at 270 nm, 292 nm, 306 nm, 340 nm, 354 nm, 360 nm, and 396 nm, indicating the presence of UV-absorbing compounds. FTIR analysis confirmed the presence of hydroxyl (-OH), carbonyl (C=O), and aromatic (C=C) functional groups, which are characteristic of flavonoids and other bioactive compounds. These findings suggest that A. flava extract has potential as a natural UV-protective agent. Further studies on compound isolation, fractionation, and photostability assessments are required to optimize its purity and effectiveness in sunscreen formulations.
Integrative Network Pharmacology and Molecular Docking Analysis of Tinospora crispa L. for Breast Cancer Therapy Dewi, Mirnawati; Ariefin, Mokhamat; Yolan Kalalinggi, Septaria; Andini, Novelia; Jipasca, Elon
Chempublish Journal Vol. 10 No. 1 (2026): Chempublish Journal (January - June)
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Breast cancer remains one of the leading mortality causes of disease related to cancer. Therefore, it is necessary to explore novel alternative therapeutic, particularly through the utilization of plant-derived natural product. Tinospora crispa L. contains diverse bioactive compounds with reported antioxidant and anticancer activities. This study integrates network pharmacology and molecular docking approaches to elucidate the molecular mechanisms of T. crispa against breast cancer. A total of 72 overlapping targets were identified between T. crispa compounds and breast cancer-related proteins, forming a highly interconnected PPI network consisting of 72 nodes and 340 edges. Clustering and enrichment analyses revealed that second cluster was significantly associated with cancer-related pathways, including AKT1, MAPK, and EGFR. The compound–protein–pathway network demonstrated two compound from T. crispa, apigenin and cycloeucalenone, possessed the highest degrees, suggesting their central regulatory roles. Molecular docking further confirmed these findings, showing that cycloeucalenone exhibited the strongest binding affinity toward EGFR and AKT1 through extensive hydrophobic interactions, whereas apigenin bound more stably to MAPK3 via multiple hydrogen bonds and hydrophobic interactions. These findings indicate that T. crispa compounds may exert anticancer effects by modulating multiple oncogenic pathways, supporting their potential development as multi-target agents in breast cancer therapy.
Co-Authors Alfanaar, Rokiy Andini, Novelia Andra Ari P., Eko Marwanto Heru Mulyantoro Dwi Hermayantiningsih Ansori Rahman Ariska, Risya Ayu Puspita Sari Ayuchecaria, Noverda Bela D Bibit Harianto Cahyani, Risfiah Cahyani, Risfiah Ruli Dicky Perwira Ompusunggu Dominikus Diki Wahyudi Dongoran, Junita Efriyana oksal Esintia Kristia Fatchiyatun Ni’mah Febriana Kesuma, Ruth Ferdinand Hidayat Hakim, Muh. Supwatul Harianto, Bibit Hermayatiningsih, Dwi Isaura Silalahi, Anastasya Jeddah Yanti Jipasca, Elon Kalalinggi, Septaria Yolan Komara, Nisa Kartika Krissilvio, Eka Jhonatan Lidya Tesalonika Lilis Rosmainar Maknun, Luluil Marvin Horale Pasaribu Mirnawati Dewi, Mirnawati Muhammad Hilmi Afthoni Multazam Nababan, Jessicca Nainggolan, Yuni Natania Gracia, Amanda Ni Wayan Prema Mulya Sari Ni Wayan Prema Mulyasari Ni'mah, Fatchiyatun Oksal, Efriyana Oktaviani, Revalina Paksi, Pandu Gizta Rapi Pramudita, Dimas Prianus, Okta Purba, Abed Nego Rahmi Wulandari, Oktavia Remi Ayu Pratika Retno Agnestisia Risfa Aliya Al-Hadi Rizki Rachmad Saputra Roil Bilad, Muhammad Ryu Pratiwi, Djihan Sari, Meiyanti Ratna Kumala Simangunsong, Sri Yulandari Simbolon, Wenika Siska, Amelia Siti Misbah Aisah Steven , Kur Yehezkiel Sugiani, Tina Sulistiawati, Putri Sun Theo Constan Lotebulo Ndruru Surbakti, Ranintha Br. Syaputra, Noor Angga Syarpin syarpin syarpin, syarpin Tampubolon, Mulani Jeni Lestari Tety Wahyuningsih Manurung Titik Andriani, Titik Utami Irawati Vety Sri Harlinda Ayudha Wahyuningsih Manurung, Tety Yolan Kalalilinggi, Septaria Yolan Kalalinggi, Septaria Yuliana Yuneta Yuyun Yuniarti, Yuyun