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All Journal Tekno : Jurnal Teknologi Elektro dan Kejuruan Journal of Islamic Pharmacy Jurnal Sains Komunikasi dan Pengembangan Masyarakat [JSKPM] Ilmu Budaya: Jurnal Bahasa, Sastra, Seni, dan Budaya BIOEDUSCIENCE Jurnal Biologi Tropis SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Dunia Farmasi Majalah Farmasetika Jurnal Ners MAHESA : Malahayati Health Student Journal Indonesian Journal of Electrical Engineering and Renewable Energy (IJEERE) International Journal of Science and Environment Jurnal Ekonomika Manajemen Dan Bisnis Journal of Artificial Intelligence and Digital Business Jurnal Pendidikan dan Pengabdian Masyarakat International Journal of Health, Engineering and Technology Jurnal Pengabdian Masyarakat Ilmu Kesehatan JEMABITEK Emitor: Jurnal Teknik Elektro Educalia: Journal of Educational Research
Melia Sari, Melia
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Journal : international journal of science and environment

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Toxicity Test of Catharanthus roseus Flower Extract with Brine Shrimp Lethality Test Method Sari, Melia; Surbakti, Chemayanti; Khairani, Tetty Noverita; Willy Novita Sari; Nasution, Gabriella Septiani
International Journal of Science and Environment (IJSE) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (248.402 KB) | DOI: 10.51601/ijse.v2i1.12

Abstract

Tapak dara (Catharanthus roseus) is a plant belonging to the Apocynaceae family originating from Central America and is generally grown as an ornamental plant. The purpose of this study was to determine the percentage of mortality data and the LC50 value of tapak dara methanol extract (Catharanthus roseus) against Artemia salina Leach larvae using the Brine Shrimp Lethality Test (BSLT) method. The BSLT method used consisted of 6 concentration treatments, namely 20 ppm, 60 ppm, 100 ppm, 140 ppm, 180 ppm, and 0 ppm a negative control, each of which was repeated three times. At each concentration, 10 experimental animals of 48 hours old Artemia salina Leach larvae were used. The toxic effect of the extract was identified by the percentage of mortality of Artemia salina Leach larvae using probit analysis (LC50). The results showed the linear regression equation y = 3.0809x – 12.065. This shows that the mortality of the test animals reached 50% when the compound concentration reached 34,599 ppm. Based on the toxicity test of the methanol extract of the tapak dara flower (Catharanthus roseus) using the Brine Shrimp Lethality Test (BSLT) method, in this study it was toxic because LC50>1000 ppm so it has potential as an anticancer.
Co-Authors Abadi, Syahrul Ambarwati, Dessy Anggraini, Nur Wahyu Anwar Ibrahim Triyoga Audy Lumbantoruan, Ruth Grace Awalia Br Nasution, Eza Okhy Ayningtiyas, Allivia BENNI ISKANDAR C.T, Nanda Ayu Chan, Adek Dalimunthe, Abdul Haris Diana Putri Diana, Vivi Eulis Elvira Destiansari Endriatmo Soetarto Faisal, Hendri Fawziyah, Sri Ginting, Evi Ekayanti Gustina, Rina H., Septiana Putri Hidayah, Yusriah Hindri Syahputri Khairah, Miftahul Khairah, Miftahul - Khairani, Tetty Noverita Kurniasari, Puspa Leny Leny Leny, Leny Mahara, Rifanzi Maya Oktavia, Maya Mohamad Shohibuddin Muhammad Andry Muhammad Yafiz, Muhammad Nadeak, Eva Rosalina Nasution, Ahmad Faisal Nasution, Dina Yolanda Nasution, Gabriella Septiani Nasution, Meiliza Putri Nia Novranda Pertiwi Nurhalimah, Kiki Nurma, Nurma Parhan Prasetio, Robi Purba, Sartika Purwoko, Agus Puspa, Novita Trie Ana Putri, Astuti Ardi Rahmi Susanti Revalina, Desy Rida Evalina Tarigan Riyanto Riyanto Saputra, Iwan Pahendra Saputra, Iwan Pahendra Anto Sari, Syilvi Rinda Simanjuntak, Monica Nelly Sirait, Rosida P. R. Suhadi, Angga Putra Surbakti, Chemayanti Tri Yunis Miko Wahyono Triski, Bella Gusmili Willy Novita Sari Windi Sari, Desi Yenny Anwar Yuli Chomsatu Samrotun Zuliana, Hendrik