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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Inovasi Farmasi Indonesia Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Mandala Pengabdian Masyarakat Jurnal Kesehatan Tambusai Well Being Journal Of Human And Education (JAHE) Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Contemporary Journal of Applied Sciences (CJAS) International Journal of Global Sustainable Research Bencoolen Journal of Pharmacy Gotong Royong International Journal of Contemporary Sciences (IJCS) Khidmah Nusantara Journal of Community Engagement in Health
Anis Akhwan Dhafin
Program Studi S1 Farmasi, Fakultas Ilmu Kesehatan, Universitas Kadiri, Indonesia
Religion Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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ADMET Prediction of the Dominant Compound from Mangosteen (Garcinia mangostana L.) using pkCSM: A Computational Approach Muslikh, Faisal Akhmal; Kurniawati, Evi; Ma'arif, Burhan; Zenmas, Syendriva Zeptyan; Salmasfattah, Novyananda; Dhafin, Anis Akhwan; Prasetyawan, Fendy
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i1.7271

Abstract

Mangosteen (Garcinia mangostana L.) is a plant belonging to the Guttiferae family with origins in Southeast Asia. The primary components in mangosteen peel consist of xanthones, particularly α-mangostin, which displays diverse pharmacological effects such as anti-diabetic properties, antioxidant activity, and anti-inflammatory effects. However, due to the insufficient information regarding studies on pharmacokinetics (administration, distribution, metabolism, excretion, and toxicity), the objective of this investigation is to explore pharmacokinetic predictions utilizing the pkCSM web tool. The α-mangostin compound, acquired from PubChem accessible at https://pubchem.ncbi.nlm.nih.gov/, underwent pharmacokinetic analysis using the web tool available at https://biosig.lab.uq.edu.au/pkcsm/prediction. The study findings revealed that the α-mangostin compound, subjected to pharmacokinetic analysis with pkCSM, exhibited limited distribution capability.
Utilization of Antiviral Medications in COVID-19 Patients with Chronic Kidney Disease in Hospital Saristiana, Yuneka; Prasetyawan, Fendy; Muslikh, Faisal Akhmal; Dhafin, Anis Akhwan; Mildawati, Ratna; Putri, Elsa Mahardika; Raharjo, Susilo Margining
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i1.7284

Abstract

The COVID-19 pandemic has presented a substantial global health challenge, affecting diverse patient populations, particularly those with chronic kidney disease. Hospitals are presently dependent on two antiviral medications, favipiravir and remdesivir, to mitigate the impact of this disease on patients with chronic kidney disease. This study aims to evaluate the utilization of favipiravir and remdesivir in COVID-19 patients with chronic kidney disease in a hospital setting. This research will employ a retrospective approach to gather data from the medical records of COVID-19 patients with chronic kidney disease who received treatment with favipiravir or remdesivir in the hospital. Considering the prevalence of favipiravir usage at 64% and remdesivir at 36%, this research aims to provide a comprehensive understanding of the effectiveness and associated risks of toxicity linked to these two medications in COVID-19 patients with chronic kidney disease
Analysis of the Strengthening of Bond through Playing Mobile Legends Game with the ”Son of Hippocrates E-SPORT Team” Approach Among Pharmacy Lecturers in the Environment of Kadiri University Prasetyawan, Fendy; Wahab, Charliandri Saputra; Dhafin, Anis Akhwan; Raharjo, Susilo Margining; Yuniarto, Prayoga Feri
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7591

Abstract

The surge in Mobile Legends' popularity among pharmacy professors prompts research on its impact on social dynamics and relationships. The game's team strategy elements provide a virtual space for professors to connect, shifting from traditional academic interactions. The research findings illuminate the positive influence of the Son of Hippocrates E-SPORT Team approach in playing Mobile Legends on the interpersonal closeness of pharmacy professors at Kadiri University. Collaborative aspects within the game, such as the creation of strong team bonds, enhanced communication, and support for cooperation beyond the academic sphere, contribute to an improved level of interpersonal relationships among faculty members. The Spearman Correlation Test results (r = 0.245, p = 0.005) support the established positive relationship between Mobile Legends gameplay and the Son of Hippocrates E-SPORT approach among pharmacy lecturers, with the calculated r-value (0.245) surpassing the critical r-value (0.114) and the significance value (0.005) falling below α = 0.05. This acceptance of H1 suggests a meaningful connection between Mobile Legends activities and the Son of Hippocrates E-SPORT
Description of Pharmaceutical Discussion Using Group Discussion Method Among "Kantor Pusat" Members at Kadiri University Cafeteria Prasetyawan, Fendy; Wahab, Charliandri Saputra; Dhafin, Anis Akhwan; Raharjo, Susilo Margining; Shutiawan, Muhammad Alviyan; Rianto, Sugeng
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7592

Abstract

Effective communication and pharmaceutical discussions at Kadiri University's Central Office are crucial in the current era of pharmaceutical advancements. The research focuses on exploring how group discussions enhance pharmaceutical understanding and collaboration, contributing to broader pharmaceutical science development. The methodology involves participatory observation, interviews, and document analysis to gain a comprehensive understanding of group discussion effectiveness. Philosophical discussions constitute 46% of central office discussions at Kadiri University, reflecting a significant emphasis on philosophical aspects in pharmaceutical talks. Pharmacy topics, at 35%, demonstrate a strong focus on core research areas. Political discussions, comprising 11%, indicate awareness of political implications in pharmacy management within the university. Ethics and Morality discussions, at 8%, suggest a lower focus but still acknowledge ethical dimensions in pharmaceutical discourse
Farmakoantartika Literature Study: Bioactivity of Pagodroma nivea on Fossil Deposits from Mujito Saristiana, Yuneka; Prasetyawan, Fendy; Mildawati, Ratna; Muslikh, Faisal Akhmal; Dhafin, Anis Akhwan; Raharjo, Susilo Margining; Arifin, Candra; Rofiq, Abd
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7593

Abstract

This report investigates the biodiversity of marine animals, focusing on extinct sponge species near Lesbos Island based on Aristotle's descriptions. Mujito, introduced in the literature review, is from the GeoMaud expedition in Antarctica. Various instrumental analysis methods, such as ESI mass spectrometry and NMR, contribute to a comprehensive understanding of the compounds, particularly in the context of Alzheimer's research. The pharmacantarctic literature study concludes that Antarctic Mumijo, particularly from Mujito fossil deposits, holds significant biomedical potential. It exhibits organic components like wax esters with notable biomedical activities, particularly in treating bone diseases. Additionally, Mumijo's composition resembles non-fossil samples, with wax esters dominating and unique components like α-glyceryl fatty alcohol ethers indicating neuroprotective potential. The research suggests promising applications in Oriental medicine, addressing wounds, skin diseases, tuberculosis, respiratory diseases, and neurological conditions like Parkinson's and Alzheimer's. Overall, Antarctic Mumijo showcases diverse biomedical prospects, emphasizing its organic components' therapeutic value
Forensic Pharmacy Case Study: Identification of Hazardous Mercury Content as a Whitening Agent in Beauty Cream Products Ardianto, Nanda; Prasetyawan, Fendy; Saristiana, Yuneka; Muslikh, Faisal Akhmal; Mildawati, Ratna; Dhafin, Anis Akhwan; Arifin, Candra; Rofiq, Abd
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7594

Abstract

Forensic pharmacy is crucial in identifying hazardous substances like mercury in beauty products. Counterfeit items with mercury pose health risks, emphasizing the need for accurate identification methods. The research, employing content analysis, focuses on illegal cosmetics containing mercury, aiming to understand distribution patterns and assess associated health risks. This systematic approach provides valuable insights into public health issues, contributing to safer regulatory practices. The utilization of these products may pose serious health risks to consumers. The implicated products include Temulawak New Day & Night, CAC Glow, Natural 99, HN (Day & Night), SP Special UV Whitening, Dr Original Pemutih, Super DR Quality Gold SPF 30, Diamond Cream, Herbal Plus New Day & Night, Ling Zhi Day & Night, Sj Sin Jung, Tabita, and Krim Labella. In Indonesia, the use of mercury in cosmetic products is prohibited by legislation, such as Law Number 32 of 2009 on Environmental Protection and Government Regulation of the Republic of Indonesia Number 81 of 2016 on the Security of Industrial Chemicals. Additionally, BPOM, responsible for overseeing drugs, food, and cosmetics, has issued relevant regulations
Pharmacy Philosophy in the Law of Power: The Morality of Pharmaceutical Ethics towards Rhetoric of Logic Hakim, Adiyansyah Lukman; Prasetyawan, Fendy; Saristiana, Yuneka; Muslikh, Faisal Akhmal; Dhafin, Anis Akhwan; Mildawati, Ratna; Arifin, Candra; Rofiq, Abd
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7595

Abstract

Pharmacy's evolution relies on technical and philosophical aspects. Research delves into the intricate link between pharmaceutical philosophy and legal power, emphasizing moral values in daily practice. The study aims to enhance policies, regulatory frameworks, and awareness, optimizing pharmacy's pivotal role in healthcare services. The results of this study depict an investigation and comprehension of the close interconnection between the philosophy of pharmacy, the law of power, the morality of pharmaceutical ethics, and rhetorical logic. A profound integration of these four aspects can provide a solid foundation for the development of ethical policies, maintaining the integrity of the pharmacy profession, and maximizing benefits for society. A deeper understanding of the complexity of these relationships can help shape a more sustainable and ethical future in the field of pharmacy. The findings of this research depict the complexity of these relationships, highlighting that deep integration can provide a solid foundation for ethical policies and the sustainable future of pharmacy
Edukasi Peluang Dan Tantangan Terkini Pharmacist Dengan Distruksi di Industri Farmasi Fendy Prasetyawan; Mujtahid Bin Abd Kadir; Nur Fahma Laili; Prayoga Fery Yuniarto; Datin An Nisa Sukmawati; Arifani Siswidiasari; Neni Probosiwi; Tsamrotul Ilmi; Elsa Mahardika Putri; Yuneka Saristiana; Okky Intan Mawarni; Winartiana; Nimas Ayu Rahardini; Anis Akhwan Dhafin
Khidmah Nusantara Vol. 1 No. 1 (2024): Agustus 2024
Publisher : CV.RIZANIA MEDIA PRATAMA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69533/ghy9th25

Abstract

Tingkat pengangguran yang meningkat setiap tahunnya membuat masyarakat mencari sumber informasi dengan tujuan memperoleh dan mendapatkan lapangan pekerjaan, yang dapat dicapai dengan menempuh pendidikan perguruan tinggi. Jurusan farmasi merupakan jurusan yang banyak diminati karena memiliki prospek yang biak kedepannya dan salah satu jurusan populer. Seorang farmasis dapat bekerja disektor industri, indonesia memiliki sebanyak 230 industri farmasi. Dengan jumlah industri yang banyak sehingga industri farmasi membutuhkan banyak tenaga kerja, terutama tenaga farmasi yang profesional. Selain peluang kerja di indsutri farmasi namun di era industri 4.0 ini tantangan yang dihadapi semakin besar, sehingga farmasis harus meningkatkan pengetahuan untuk mengimbangi teknologi yang terus maju. Oleh karena itu diperukan pengetahuan untuk meningkat wawasan terkait indutri farmasi.Tujuan dari kegiatan pengabdian masyarakat ini adalah untuk mendorong mahasiswa farmasi agar dapat bekerja di industri farmasi dan memberikan gambaran tentang industri farmasi. Kegiatan pengabdian ini dilakukan di gedung AULA FIK Universitas Kadiri hari sabtu, 20 April 2024. Hasil kegiatan menunjukkan bahwa peserta antusias mengikuti acara, terlihat dari keikutsertaan mereka dalam mengikuti acara dari awal hingga akhir dan mengajukan pertanyaan selama sesi kuliah pakar berlangsung.Oleh karena itu, kegiatan pengabdian masyarakat ini dinilai berpotensi membantu menginspirasi, mendorong dan informasi bagi mahasiswa farmasi untuk berkarir di industri farmasi.
Analysis of Drug Use and Potential Interactions in Type 2 Diabetes Inpatients at a Type C Hospital, Kediri (2024) anis akhwan dhafin; Luh Santhi Utami Wiryani; Elsa Mahardika Putri; Herman Herman; Pulung Prabowo; Prayoga Feri Yuniarto; Winartiana Winartiana
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.641

Abstract

Bachelor of Pharmacy, Universitas Mahasaraswati Denpasar, Indonesia Corresponding Author: anisdhafin13@unik-kediri.ac.id ABSTRACT Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a high prevalence and frequent comorbidities, particularly hypertension, which often require multidrug therapy and increase the risk of drug interactions. This study aimed to analyze the pattern of antidiabetic drug use and the potential for drug interactions in hospitalized patients with T2DM at a type C hospital in Kediri City during June–December 2024. The research employed a retrospective descriptive design using medical record data of 44 patients who met the inclusion criteria. Data were analyzed descriptively and presented in frequency distribution tables. Results showed that the most commonly prescribed drug class was biguanides (26.25%), followed by sulfonylureas (21%), insulin (21%), and α-glucosidase inhibitors (12.5%). Combination therapy was widely used, particularly the combination of two oral antidiabetic agents. Potential drug interactions were identified in 72.73% of patients, with moderate interactions being the most frequent (78.13%), followed by minor (12.5%) and major (9.38%) interactions. The most common interactions included metformin with amlodipine or ramipril (moderate severity), captopril with hydrochlorothiazide (minor severity), and simvastatin with amlodipine (major severity). However, in this study polypharmacy was defined as the concomitant use of ≥5 medications. These findings indicate that such polypharmacy in T2DM patients with hypertension substantially increases the likelihood of drug interactions, underscoring the importance of careful monitoring and rational prescribing to improve patient safety
Studi In Silico Senyawa Daun Sambung Nyawa (Gynura procumbens (Lour.) Merr.) terhadap HER2 dan EGFR sebagai Antikanker Payudara: In Silico Study of (Gynura procumbens (Lour.) Merr.) Compounds Against HER2 and EGFR as Breast Anticancer Mohammad Firdaus Alshol; Datin An Nisa Sukmawati; Novyananda Salmasfattah; Fendy Prasetyawan; Anis Akhwan Dhafin
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 7 No. 2 (2026): Volume 7 Nomor 2, Juni 2026
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v7i2.7723

Abstract

Kanker payudara adalah neoplasma ganas dengan karakteristik biologis yang beragam sehingga mmerlukan terapi spesifik. Pendekatan komputasi, seperti penambatan molekuler, simulasi dinamika molekuler, dan prediksi ADMET, banyak digunakan untuk mengidentifikasi kandidat obat antikanker secara efisien. Studi ini bertujuan untuk menghasilkan senyawa bioaktif potensial dari Daun Sambung Nyawa (Gynura procumbens (Lour.) Merr.) terhadap protein target HER2 dan EGFR sebagai kandidat obat kanker payudara. Penambatan molekuler dilakukan menggunakan AutoDock 4.0. Senyawa dengan energi terendah kemudian dianalisis melalui simulasi dinamika molekuler menggunakan YASARA dan sifat farmakokinetik dan toksisitasnya diprediksi berdasarkan parameter ADMET. Hasil menunjukkan bahwa beberapa senyawa memiliki afinitas pengikatan yang baik terhadap HER2 dan EGFR dan membentuk kompleks yang stabil berdasarkan nilai RMSD dan RMSF. Prediksi ADMET menunjukkan profil yang mendukung pengembangan lebih lanjut sebagai kandidat obat kanker payudara oral.
Co-Authors Adhitama, Laily Vitria Ardianto, Nanda Arifani Siswidiasari Candra Arifin, Candra Charliandri Saputra Wahab Datin An Nisa Sukmawati Elsa Mahardika Dhafin Elsa Mahardika Putri Elsa Mahardika Putri Elsa Mahardika Putri Elsa Mahardika Putri Elsa Mahardika Putri Evi Kurniawati, Evi Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Fendy Prasetyawan Fita Sari Hakim, Adiyansyah Lukman Herman Herman Herman Herman Hidayati, Evi Nurul Intan Mawarni, Okky Khadir, Mujtahid Bin Abd Kusumawati, Leny Witaning Laili, Nur Fahma Luh Santhi Utami Wiryani Lukitasari, Dhunik M. Wahyu Ariawan Ma'arif, Burhan Maharani Dwi Pritiwi Maharani Dwi Pritiwi Mawarni , Okky Intan Mawarni, Okky Intan Mildawati, Ratna Mohammad Firdaus Alshol Muhammad Alviyan Shutiawan Mujtahid Bin Abd. Kadir Neni Probosiwi Nimas Ayu Rahardini Novyananda Salmasfattah Nur Fahma Laili Okki Intan Mawarni Okki Intan Mawarni Okky Intan Mawarni Okky Intan Mawarni Pertiwi, Maharani Dwi Pratiwi, Maharani Dwi Prayoga Feri Yuniarto prayoga fery yuniarto Pulung Prabowo Putri , Elsa Mahardika Putri, Elsa Mahardika Raharjo, Susilo Margining Rofiq, Abd Rosa Juwita Hesturini Salmasfattah, Novyananda Setyawan, Ferdinta Daniasta Shutiawan, Muhammad Alviyan Sugeng Rianto Sugeng Santoso Sukmawati, Datin An-Nisa Susilo Margining Raharjo Tsamrotul Ilmi Winartiana Winartiana Winartiana Winartiana Winartiana Winartiana, Winartiana Wiryani, Luh Santhi Utami Yuneka Saristiana Yuniarto, Prayoga Feri Yuniarto, Prayoga Fery Zenmas, Syendriva Zeptyan