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All Journal Jurnal Kesehatan Tambusai Integrated Science Education Journal Innovative: Journal Of Social Science Research Detector: Jurnal Inovasi Riset Ilmu Kesehatan PPSDP International Journal of Education Mutiara: Jurnal Penelitian dan Karya Ilmiah Nian Tana Sikka: Jurnal Ilmiah Mahasiswa Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan dan Keperawatan Medic Nutricia : Jurnal Ilmu Kesehatan Intellektika: Jurnal Ilmiah Mahasiswa Mikroba: Jurnal Ilmu Tanaman, Sains dan Teknologi Pertanian Pentagon: Jurnal Matematika dan Ilmu Pengetahuan Alam Polygon: Jurnal Ilmu Komputer dan Ilmu Pengetahuan Alam Algoritma: Jurnal Matematika, Ilmu Pengetahuan Alam, Kebumian dan Angkasa Jurnal Ilmu Psikologi dan Kesehatan Menulis: Jurnal Penelitian Nusantara Jurnal Pendidikan Kimia, Fisika dan Biologi Jurnal Cakrawala Pendidikan dan Biologi (jucapenbi) Konstanta : Jurnal Matematika dan Ilmu Pengelatuan Alam
Ardi Mustakim
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Review Artikel Uji Kandungan Estrak Biji Kemiri (Aurites Moluccana L. Willd) sebagai Penumbuh Rambut Dea Lestari; Ardi Mustakim
Jurnal Cakrawala Pendidikan dan Biologi Vol. 1 No. 4 (2024): Desember: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v1i4.59

Abstract

In Jambi, research has been conducted on candlenut seed extract which has been proven to be of high quality and has been widely marketed throughout Indonesia. The purpose of this study was to evaluate the effectiveness of candlenut seed extract (Aurites moluccana L.) on various hair problems such as graying and hair loss. This study is a literature study that uses data collection methods from library sources. Secondary data is compiled and analyzed to reach conclusions regarding the topic studied. Candlenut plants (Aleurites moluccana L.) have the potential as hair fertilizers and health care, thanks to the content of saponins, flavonoids, and polyphenols found in seeds, leaves, and roots. The Dayak ethnic group uses burned candlenut fruit for hair care. In addition, candlenuts also function as a medicine for flu and colds, and have anticancer properties. The conclusion of this review is to support the potential of candlenut seed extract as a solution to hair problems However, further research is needed to understand how the active ingredients involved work and to standardize testing methods to ensure the clinical application of the extract's efficacy.
Pemanfaatan Ekstrak Gel Lidah Buaya (Aloe Vera) Terhadap Bakteri Propionibacterium Acnes Suci Fabilla; Ardi Mustakim
Jurnal Cakrawala Pendidikan dan Biologi Vol. 1 No. 4 (2024): Desember: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v1i4.60

Abstract

The aim of this study was to test the effectiveness of aloe vera gel extract (Aloe Vera) against the Propinibacterium acnes bacteria, which is the main cause of acne on human skin. Aloe vera is known by the scientific name Aloe Vera L. and has long been used by people as an ingredient in cosmetics, skin care, wound healing and hair fertilizer. The methods used in this literature review include sampling aloe vera gel extract, testing antibacterial activity against Propionibacterium acnes bacteria, and data analysis to determine the effectiveness of the extract. Although there are differences in testing methods and concentrations used, most studies show this extract is effective in inhibiting Propionibacterium acnes bacteria. The conclusion of this review provides a safer alternative for treating acne using herbal products compared to using antibiotics.
Aktivitas Antibakteri Ekstrak Kecombrang (Etlingera Elatior) dan Kalanduyung (Cassia Siamea) terhadap Pertumbuhan Bakteri Serta Pengaruh Rokok terhadap Kualitas Sperma Mencit Jantan Airin Nurfaiza; Ardi Mustakim
Jurnal Cakrawala Pendidikan dan Biologi Vol. 1 No. 4 (2024): Desember: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v1i4.70

Abstract

Bacterial growth is one processes carried out through binary fission for its reproduction process. Bad bacteria in their growth process must course be inhibited in several ways, one which is through the consumption several herbal or traditional plants, such as torch ginger and kalanduyung extracts. The dangers cigarette smoke can reduce the health individuals. Cigarette smoke can have an impact on reducing the number of spermatozoa caused by decrease in the diameter seminiferous tubules for 45 days. The purpose writing journal is to analyze antibacterial activity of torch ginger and kalanduyung extracts on bacterial growth and the effect of cigarettes on the quality male mouse sperm. The writing method uses qualitative type. The results and conclusions that bacterial growth can be inhibited by consuming several traditional plants such as torch ginger extract and kalanduyung leaf extract. In inhibiting growth of antibacterial activity, torch ginger extract has quite good effectiveness with concentration value 20%. The value inhibition zone formed is 17.22. The use largest concentration, namely 80%, has an effective inhibition of bacterial growth which is known to have an average inhibition zone value of 14.9 mm. Furthermore, the quality male mouse sperm does not have specific effect on the provision control treatment related to provision amount of cigarette smoke.
Potensi Farmakologi dari Ekstrak Tumbuhan Berkhasiat sebagai Suplemen Antidiabetes, Antioksidan, dan Antimalaria Marvina Marvina; Ardi Mustakim
Jurnal Cakrawala Pendidikan dan Biologi Vol. 1 No. 4 (2024): Desember: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v1i4.71

Abstract

Health is a condition where the body system and organs in the body can carry out their respective functions. However, in some cases that occur in Indonesian society, health problems have begun to appear, such as diabetes, malaria, and so on. According to the analysis, the incidence of diabetes continues to increase every year. Furthermore, the plant extract that is used as a source of antioxidants is bamboo shoots. The incidence of malaria resistance has reached >25% so that several drugs such as chloroquine are no longer used as the main drug in cases of malaria. The purpose of writing is to analyze the results of a review of the pharmacological potential of plant extracts that are effective as antidiabetic, antioxidant, and antimalarial supplements. The writing method used in writing this journal is to use a qualitative type. The results of the study are that bamboo leaf extract provides effectiveness as an antioxidant. Furthermore, antidiabetic can be found in the extract of the butterfly pea flower. Then the extract of the moon flower leaf has effectiveness as an antimalarial. The conclusion drawn is that the use of natural plant extracts can be used as antidiabetic, antioxidant, and antimalariall.
Review Artikel Teori Evolusi Sel Prokariotik, Eukariotik dan Penyusun Membran Sel Citra Bunga Lestari; Ardi Mustakim
Jurnal Cakrawala Pendidikan dan Biologi Vol. 1 No. 4 (2024): Desember: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v1i4.77

Abstract

Understanding the evolution of cells is very important, which means studying the development of living things. The smallest structural elements of living things are cells. These cells gradually change both their structure and function. It can be said that almost all biologists can accept the theory of biological evolution or the theory of evolution that continues to develop , even though the theory is based on circumstantial evidence . The principle of this evolutionary theory is that humans, animals, and plants all evolve continuously. This journal is based on the narrative review method and displays a narrative review design from research journals related to the theory of prokaryotic, eukaryotic, and cell membrane-related evolution. The importance of cells continues to develop along with advances in technology and the discovery of sophisticated tools. Until now it is known that the structure and activities of cells are not as simple as previously thought. Cells that exist today are the result of evolution towards more refined cells. and There are many details in cell evolution that cannot yet be explained.
Analisis Struktur Jumlah Sel Darah untuk Pembelajaran pada Mahasiswa Farmasi Indah Maisyarah Buliani; Ardi Mustakim
Jurnal Cakrawala Pendidikan dan Biologi Vol. 2 No. 1 (2025): Maret: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v2i1.142

Abstract

This research aims to analyze the summation of blood cells so that it becomes a reference for pharmacy students in their learning and becomes the foundation for further study of pathology, pharmacology, and therapeutic mechanisms that they can use in professional practice. This study uses qualitative research, primary data sources and secondary data sources generated from literature studies, data types in the form of qualitative, data collection techniques in the form of tracing previous research, data analysis techniques in the form of qualitative descriptive. Blood is one of the organs in the human body that is very vital. Blood is a unit consisting of blood cells and blood plasma. This analysis is carried out to obtain information about the sum of blood cells in the human body, hospitals or laboratories conduct blood analysis with excellent accuracy but the shortcomings lie in the slow process and the accuracy becomes non-standardized because it depends on the level of expertise/experience of the operator and also the level of fatigue. Efforts to overcome the length of time and for the purpose of initial diagnosis can use image processing techniques based on blood cell morphology. Along with the development of technology, there are currently several researchers who are conducting various studies in the application of computerized methods used in the classification of white blood cell types. The main function of red blood cells is to carry oxygen from the lungs and distribute it throughout the body. The analysis of human blood is very important, especially related to the diagnosis of a disease. Based on the results of this study, it shows how many red blood cells are present in the body and can be applied to detect a disease. For pharmacy students, an understanding of the sum of blood cells is necessary to develop knowledge and will be useful in clinical practice.
Mekanisme Tensegritas Sel dan Regulasi Imun oleh mikroRNA : Memahami Interaksi Kompleks dalam Sistem Imun Mamalia Teuku Daffa Hasian; Ardi Mustakim
Jurnal Cakrawala Pendidikan dan Biologi Vol. 2 No. 1 (2025): Maret: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v2i1.148

Abstract

Modern cellular tissues have evolved into cell tensegrity structures, where cell strength and stability are established through supportive interactions. Tensegrity improves the efficiency of frequency spectrum use and signal quality in cellular networks. Research shows miRNAs play an important role in the regulation of gene expression in the immune system, providing new insights into the complexity of modern biological systems. Structural Design of Cellular Tissues involves computer simulation studies and laboratory experiments on cell tensegrity. Immune Regulation by MicroRNAs includes analysis of MiRNA gene expression and functionality using technologies such as microarrays and high-throughput sequencing. Data Integration includes identifying microRNA gene targets and understanding transcriptional regulation through methods such as reporter gene assays and Chromatin Immunoprecipitation to predict cellular responses in clinical scenarios. The complex interplay between cellular tensegratas mechanisms and immune regulation by microRNAs shows how widespread their interactions are in human biological systems. The cellular tensegratas structure helps improve intercellular communication, while immune regulation by microRNAs ensures the body's proper response to pathogens. Recent research on microRNAs has exposed their role in the development and function of mammalian immune cells. MiRNAs play an important role in the development and function of mammalian immune cells. The complex interactions between cellular tensile mechanisms and immune regulation by microRNAs demonstrate how structural and functional integration can improve the performance of human biological systems. Integration of these data provides a complete picture of the complexity of modern biological systems and their clinical implications in the diagnosis and treatment of immunological diseases.
Inovasi Terbaru dalam Terapi Gen, Terapi Berbasis Sel, dan Pengembangan Obat Anti Kanker dari Bahan Alam Muthiya Amalia; Ardi Mustakim
Jurnal Cakrawala Pendidikan dan Biologi Vol. 2 No. 1 (2025): Maret: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v2i1.150

Abstract

Cancer therapy has undergone remarkable advancements in recent decades, driven by innovations in gene therapy, cell-based therapy, and the development of anti-cancer drugs from natural products. Gene therapy offers the possibility of correcting genetic mutations that cause cancer, while cell-based therapies, such as CAR-T cell therapy, provide personalized and effective solutions. Additionally, the exploration of natural compounds continues to be a promising approach in anti-cancer drug development. This paper discusses recent progress in these three fields, highlighting their potential, challenges, and implications for future clinical applications.
Penelitian Terapi Berbasis Sel Perkembangan Baru dalam Immunoterapi dan Gen Theraphy Nayla Fazilla Nadin; Ardi Mustakim
Jurnal Cakrawala Pendidikan dan Biologi Vol. 2 No. 1 (2025): Maret: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v2i1.152

Abstract

Research into cell-based therapies has grown rapidly in recent years, particularly in the context of immunotherapy and gene therapy. Cell-based therapy is an innovative approach that uses living cells, such as genetically modified T cells, to recognize and destroy cancer cells or other diseases. Additionally, developments in gene therapy allow scientists to edit or repair damaged genes, thereby restoring normal cell function. This research aims to explore recent developments in cell-based therapies, as well as their impact on immunotherapy and gene therapy. The main focus is on methods used to modify cells, such as CRISPR/Cas9 technology, as well as techniques to improve the ability of immune cells to target and kill cancer cells. The research also covers the challenges faced in this therapy, including the risk of side effects, genetic stability, and sustainability of transplanted cells. The research results show that cell-based therapies offer new hope in the treatment of difficult-to-treat diseases, such as cancer and rare genetic disorders. However, further research is still needed to ensure its long-term safety and effectiveness. This research is expected to provide in-depth insight into the potential and challenges of cell-based therapies, as well as providing a basis for future clinical development.
Analisis Stuktur Sel dan Perkembangan Sel Limfosit B dan Sel Limfosit T Serta Mekanismenya Ni’matullathifah Ni’matullathifah; Ardi Mustakim
Jurnal Cakrawala Pendidikan dan Biologi Vol. 2 No. 1 (2025): Maret: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v2i1.160

Abstract

B lymphocyte cells and T lymphocyte cells are two important types of cells in the human body's immune system. B Lymphocyte cells are responsible for producing antibodies that identify and help eliminate pathogens, such as bacteria and viruses. They also play a role in the adaptive immune response and can become memory cells, allowing the body to respond more quickly if exposed to the same pathogen in the future. T lymphocytes on the other hand, function in the recognition and destruction of cells infected by viruses as well as in regulating the immune response. T cells can be divided into several subtypes, including cytotoxic T cells, which directly destroy infected cells, and helper T cells, which help coordinate the immune response by secreting cytokines. These two types of cells work together to provide effective protection against infection and contribute to immunological memory, which is important for long-term immunity
Co-Authors Afifatur Rizqiah Afreni Hamidah Agistha Dwi Lestari Airin Nurfaiza Aisha Noviadianty Anattri, Lega Andini Anggun Sarttika Erinza Annisa Tuzzahra Arfina, Nabila Arifa, Rifka Fadhlina Arum Dwi Arimbi Astari, Milla Aulia Ramadhani Azzahra, Syasya Bambang Hariyadi Citra Bunga Lestari Dea Lestari Dea Miranda Saputri Dian Novita Dina Oktalia Putri Dini Anjani Evelyn Luna Anggraini Fathiya Rizki Aninda Felisha Putri Maida Fhariza Liandri Chardy Ilham Falani Indah Maisyarah Buliani Indri Artanti Intan Hapsari Isnaini Yulia Lestari Kayla Khairatifah Zalianti Keila Ramadhani Khalim Purnomo Khusnul Khotimah Rijie Latifatus Zahroh Leviona Dhina Safira Lilik Hevinovisa Lisa Fitriana Luciana Bunga Sari Lulu Wafiq Wafizo Marsya Marsya Marvina Marvina Maura Maharani Mayla Fasha Azla Milla Astari Mulyadi, Elvaro Islami Muthiya Amalia Nailla Indayani Sumardi Nanik Apriyanti Nasanda, Fika Nasanda, Shafitri, Fika Nawra Nurvidilla Nayla Azzahrah Nayla Fazilla Nadin Nazwa Nayla Putri Nindy Adisha Puti Hanumsari Nirmala Nirmala, Nirmala Ni’matullathifah Ni’matullathifah Ni’matullathifah Novita Maharani Nyimas Fatiyah Aini Oktalia Putri, Dina Okti Sonya Rahmadani Purnomo, Khalim Putri Rahmadani Putri, Dina Oktalia Queenara Yulianingtyas, Mutia Ratu Zara Rezky Maulidiya Rifky Rifaldo Munthe Sabnatun Nikmah Saffana Aura Balqis Salsabila Rahman Setiana Safitri Shafitri Shafitri Shafitri, Shafitri Siti Dwi Cahira Sri Nanda Suci Fabilla Suci Tri Ramadhani Tamimil Hasanah Tassa Tassa Tata Anggraini Teuku Daffa Hasian Tiara Nabila Putri Tiara Nabilah Putri Yulianingtyas, Mutia Queenara Zaskia Rahmawati Zinda Rizkia Aprilia