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All Journal International Journal of Public Health Science (IJPHS) Jurnal Media Gizi Indonesia (MGI) GIZI INDONESIA AcTion: Aceh Nutrition Journal Jurnal Ilmiah Keperawatan Sai Betik Jurnal Dunia Kesmas Jurnal Kesehatan JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Aisyah : Jurnal Ilmu Kesehatan Borneo Journal of Medical Laboratory Technology Jurnal Pengabdian Masyarakat Multidisiplin Jurnal Pengabdian Masyarakat Indonesia Al-Mu'awanah Jurnal Ilmiah Kesehatan (JIKA) Journal of Oral Health Care JOMPA ABDI: Jurnal Pengabdian Masyarakat Jurnal Pangan Kesehatan dan Gizi (JAKAGI) Journal of Public Health Concerns Jurnal Gizi dan Kesehatan JOURNAL OF Qualitative Health Research & Case Studies Reports Jurnal Kesehatan Metro Sai Wawai Jurnal Pendidikan Kesehatan Journal of Dietetics Science
Rahmadi, Antun
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Effects of soy plus zinc supplementation on growth and kidney health in Wistar rats: Implications for childhood stunting prevention Yuniastini, Yuniastini; Purwati, Purwati; Rahmadi, Antun; Sulastri, Sulastri; Wiratmoko, Wien; Prasetio, Iradah Lia; Busman, Hendri; Al Hafidz, Muhammad; Mz, Fannia Khairani; Hak, Mohammad Hafid
International Journal of Public Health Science (IJPHS) Vol 15, No 1: March 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i1.26895

Abstract

Zinc deficiency can cause growth and health problems, whereas protein from soy sources contributes to essential nutritional intake. This study aimed to evaluate the effects of soy plus zinc (SPZ) supplementation on growth and kidney health in Wistar rats. This study used a randomized controlled trial design with 24 rats divided into five treatment groups, including a control group. SPZ supplementation was administered daily for 14 days with varying zinc doses (0.020 mg and 0.035 mg per gram of body weight) and palatability enhancement using vanilla flavoring. Data obtained through measurements of initial and final body weights and kidney weights were analyzed using ANOVA to determine significant differences between groups. The results showed that SPZ supplementation positively contributed to growth, as evidenced by a significant increase in the final weight of rats compared to their initial weight (p < 0.05). Histological analysis of the kidneys indicated no visible structural damage, and the average increase in kidney weight was approximately 26.5%. The combination of soy and zinc in SPZ was shown to have a synergistic effect that benefits the development and kidney health of rats, demonstrating its potential application in the context of animal nutrition.
Co-Authors Abdullah Abdullah Adinda Juwita Sari Agung Riyadi Agusta, Ryan Ahmad Fikri Al Hafidz, Muhammad Anggun Rusyantia Aprina Arie Nugroho Arie Nugroho Arie Nugroho, Arie Bertalina Bertalina Bertalina Bertalina Bertalina Ny Demsa Simbolon Dewi Sri Sumardila Dewi Sri Sumardilah Dewi Sri Sumardilah Dewi Sri Sumardilah Endang Sri Wahyuni Endang Sri Wahyuni Fitricia Andreani Hak, Mohammad Hafid Hanung Ismoyo Hendri Busman INDRASARI, NELLY Jumiyati Jumiyati Jumiyati Lisma Ningsih Lupiana, Mindo Mulyani, Roza Mz, Fannia Khairani Nawasari Indah Putri S. Novika J, Yulia Ny, Bertalina Prasetio, Iradah Lia Prasetiowati , Lies Elina Pratama, Agil Surya Fajar Purnomowati , Ratnasari Dyah Purnomowati, RR. Ratnasari Dyah Purwati Purwati Ratnasari Dyah Purnomowati Rauf Tamim Reni Indriyani Retno Puji Hastuti Rina Mariani Roza Mulyani Ryan Agusta Sefanadya Putri Sejati, Nawasari Indah Putri Siswahyudianto Sofyan Musyabiq Wijaya Sri Sumardillah, Dewi Sudarmi Sudarmi Sulastri Sulastri Sumardilah, Dewi Sri Sutrio Sutrio Sutrio Sutrio Sutrio Sutrio Sutrio Sutrio Sutrio Usdeka Muliani Wiratmoko, Wien Yulia Novika J Yunianto, Andi Eka Yuniastini, Yuniastini Yustin Nur Khoiriyah