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All Journal Buletin Peternakan Jurnal Kedokteran Syiah Kuala Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Keperawatan
Afif Nurul Hidayati
Departemen/ Staf Medik Fungsional Ilmu Kesehatan Kulit Dan Kelamin Fakultas Kedokteran Universitas Airlangga / Rumah Sakit Umum Daerah Dr. Soetomo Surabaya Rumah Sakit Universitas Airlangga
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary Other

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Evaluation of Histopathology Findings of Clinically Confirmed Psoriasis Vulgaris Sawitri; Fadila, Arisia; M. Yulianto Listiawan; Priangga Adi Wiratama; Dwi Murtiastutik; Evy Ervianti; Linda Astari; Damayanti; Diah Mira Indramaya; Afif Nurul Hidayati; Medhi Denisa Alinda
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 1 (2023): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.1.2023.21-26

Abstract

Background: Psoriasis vulgaris can be diagnosed clinically. A biopsy is usually used to confirm non-classic cases. The findings of the histopathology feature are not usually present, thus clinical relevance is needed to confirm the diagnosis. Purpose: To describe the histopathology findings from tissue samples of histopathologically confirmed psoriasis vulgaris reported in the Department of Pathology and Anatomy of Dr. Soetomo General Hospital. Methods: A descriptive-retrospective study of pathology-ascertained tissue samples of histopathologically confirmed psoriasis vulgaris was reported in the Department of Pathology and Anatomy from patients who were also previously diagnosed clinically with psoriasis vulgaris in the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital over a period of 2 years. Morphological parameters were observed after histopathology sections were stained with hematoxylin and eosin. Result: Thirty-three tissue samples were examined. Parakeratosis (86%) and hypogranulosis (70.3%) were the most observed findings. Club-shaped rete ridges, suprapapillary plate thinning, and spongiform pustules of Kogoj were the least observed findings (each by 2.7%). Three tissue samples (8.1%) showed only parakeratosis. Only 1 tissue sample (2.7%) showed 4 features (absence of the granular layer, parakeratosis, microabscess of Munro, and spongiform pustules of Kogoj). No tissue sample showed every histopathology finding of psoriasis vulgaris. Conclusion: All of the histopathology features of psoriasis vulgaris are rarely found in one tissue section. Albeit histopathology is believed to be the gold standard diagnosis of psoriasis vulgaris, relevance with clinical findings is still mandatory to support the diagnosis.
Co-Authors Alfrid Asditya Alpha Fardah Athiyyah Amanda Gracia Manuputty Anang Endaryanto Annisa Fitriana Aprilawati, Dwi Arisia Fadila As'ad Naufal Astindari Astindari Astindari Budi Utomo Budi Utomo Budi Utomo BUDI UTOMO Budiono Budiono Chesia Christiani Liuwan Cita Rosita Sigit Prakoeswa Cut Shelma Maharani Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Deasy Fetarayani Desiana Widityaning Sari Diah Mira Indaramaya Diah Mira Indramaya Dias Lidiana A.S Dwi Murtiastutik Dyah Ayu Pitasari Dyatiara Devy Rahadiyanti Efenina Ginting Emma Hidayati Sasmito Erwin Astha Triyono Evy Ervianti Fadila, Arisia Fatimah, Nurmawati Fikri Ardhani Hari Sukanto, Hari I G.A. Kencana Wulan Icha Aisyah Indah Purnamasari Indah Purnamasari INDROPO AGUSNI Ingrid Suryanti Suryono Isaak Effendy Isaak Effendy Iskandar Zulkarnain Iskandar Zulkarnain Kristina Sihaloho KUSUMASTUTI, ETTY HARY laissa Bonita Linda Astari, Linda M. Yulianto Listiawan Maylita Sari Medhi Denisa Alinda, Medhi Denisa Melida Agustina Nurina Hasanatuludhhiyah Pepy Dwi Endraswari, Pepy Dwi Pramita Ariyanti Priangga Adi Wiratama Rahmadewi Rahmadewi Rahmadewi Renata Prameswari Retha Retha Ridha Ramadina Widiatma Saut Sahat Pohan Sawitri Sawitri Sawitri Sawitri Sawitri Senda Sulvain Rahmaningrat Septiana Widyantari Shinta Dewi Rahmadhani Sigit Eko Prabowo Siti Isrina Oktavia Salasia Sudjarwo Sudjarwo Sunarso Suyoso Wahyunita Desi Ratnaningtyas Wardiana, Maya Widodo J. Pudjirahardjo William Andrew Isaac Windhu Purnomo Wisnu Triadi Nugroho Yuri Widia, Yuri