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Journal : Medicra (Journal of Medical Laboratory Science/Technology)

The Effect Of Using Personal Protection Equipment (PPE), Mileage, And Smoking Habits On Hair Lead (Pb) Levels: Pengaruh Penggunaan Alat Pelindung Diri (APD), Jarak Tempuh Dan Kebiasaan Merokok Terhadap Kadar Timbal (Pb) Rambut Wulandari, Devyana Dyah; Rohmah, Wardah; Nidianti, Ersalina; Santoso, Andreas Putro Ragil; Andini, Ary
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.1435

Abstract

Street sweepers, traffic officers, roadside sellers and motorcyclists, including students are subjects who are vulnerable to exposure to vehicle fumes. One of the air pollution generated from motor vehicle fumes is lead (Pb) which is toxic to humans and is accumulative. This study aimed to analyze the relationship between characteristic factors and lead levels in hair using the Atomic Absorption Spectroscopy (AAS) method. Respondents in this study were 32 male university students. The results showed a significance value of 0.274 (p> 0.05) on the parameter of PPE use, 0.049 (p <0.05) on the mileage parameter, and 0.576 (p> 0.05) on the smoking habit parameter. So it can be concluded that there is no effect of the use of PPE and smoking habits on hair lead levels and there is an effect of mileage on hair lead levels in student respondents.
Hubungan Paparan Pestisida Kadar Enzim Kolinesterase dengan Kadar Trigliserida pada Pekerja yang Terpapar Pestisida Golongan Organofosfat: Relationship of Pesticide Exposure to Cholinesterase Enzyme Levels with Triglyceride Levels in Workers Exposed to Organophosphate Group Pesticides Santoso, Andreas Putro Ragil; Wulandari, Devyana Dyah
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 2 No. 2 (2019): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v2i2.2992

Abstract

Alzaimer degerative diseases that attack the brain that occur due to several things including cholesterol and poisoning due to organopathic pesticides, cholinesterase. Triglycerides are a part of kolesterol which consists of about 20% of total cholesterol. Pesticide buildup in the body often occurs due to work risks. This study aims to determine how much cholinesterase activity and triglyceride levels are in workers exposed to organophosphate pesticides, and to determine the relationship of pesticide exposure to cholinesterase enzyme levels with triglyceride levels in workers who are exposed to workers exposed to pesticides. This research is an observational research with an experimental approach. The study was conducted at PT.X, which was exposed to 15 pesticides. This study uses a correlation test that will be shown if p <0.05. Based on the results of the study obtained based on the average results of cholinesterase activity obtained at 8,040 U/L while triglycerides at 186 mg/dL. And after the correlation test was obtained at 0.085 indicating that p> 0.05 so it was concluded that there was no relationship between cholinesterase activity with triglyceride levels.
Correlation Isocitrate Dehydrogenase Level and Triglyceride Level in Rats Stimulated with Ethanol Extract of Moringa Leaf: Hubungan Kadar Isositrat Dehidrogenase dengan Kadar Trigliserida pada Tikus yang Distimulasi dengan Ekstrak Etanol Daun Kelor Fitriana Sari, Devi; Wulandari, Devyana Dyah; Wardany, Nadya Ika; Baskara, Muhamad Damar; Nadzarillah, Najmatul Jannah
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i2.1768

Abstract

Food substances are oxidized through mitochondria to produce chemical energy in the form of adenosine triphosphate (ATP), which is used as energy. The Krebs cycle uses the energy produced by the body to make adenosine triphosphate. A class of enzymes known as dehydrogenases including isocitrate dehydrogenase (IDH) is responsible for electron transport from substrate to electron receiver. In addition, IDH is involved in various cellular processes, including lipogenesis, which is part of lipid metabolism. This study aimed to investigate the relationship between triglyceride (TG) levels and mitochondrial IDH enzyme activity with respect to taking ethanol extract of Moringa oleifera leaves. This type of research is experimental with a control group design. The samples in this study were 20 white rats divided into 5 treatment groups, namely Negative Control (K-) rats with normal conditions, Positive Control (K+) rats with tired conditions, Standard Group (STD) rats with creatinine drug induction, Treatment 1 (P1) rats given 250 mg/kgBB dose of Moringa oliefera leaf extract, Treatment 2 (P2) rats given 500 mg/kgBB dose of Moringa Oliefera leaf extract. The results of statistical analysis of the correlation test p value 0.147 ≥0.05 can be concluded that there is no relationship between IDH enzymes and TG.
Co-Authors , Wirda Nur Fa'ida Adela Puspitasari Aditiya Putri, Ngiluhtara Dyah Aguslina Kirtishanti Aguslina Kirtishanti Aini, Fadlilah Nur Aishella, Maulida Akhmad, Nur Faradila Alfian Daffa Alkatiri, Wardah Andini, Ary Andreas Putro Ragil Santoso, Andreas Putro Ragil Ardyarini Dyah Savitri Ardyarini Dyah Savitri Arvian Nur Amalina Audina, Miea Ayu Wuryaningrum Baskara, Muhamad Damar Bintarti, Tri Wahyuni Choirotussanijjah Choirotussannijah Choirotussannijah Damar Baskara, Muhammad Dyah Dedi, Muhamad Derrizkie Divanda Herzhaputra Devyani Diah Wulansari Devyani Diah Wulansari Devyani Dyah Wulansari Dewi Masitah Dwi Handayani Emma Savitri Endah Budi Permana Putri Ersalina Nidianti Eva Tri Wulandari Fadlilah Nur Aini Fauziah, Luqiana Fitriana Sari, Devi Gilang Nugraha Halimah Prisilia Herliani Rahmania Sari Hermawati, Septina Isro’ Hotimah Masdan Salim Illahi, Wahyu Imastufah Imratul Mukarramah Indah Lestari Janetra Yudhis Nata P Kifli, Nurolaini Krisdayanti, Affina Lili Susan Rahmawati Lysa Veterini Ma'at, Suprapto Maghfuroh, Qonita Iklila Mella Rahmawati Mukminin Mellyisa Mochamad Nurul Lail Mufida, Nisaul Muhammad Afwan Romdloni Muhammad Fadillah, Farchan Muhammad Taufiq Hidayat Mukarramah, Imraatul Mukhtar Adi Nugroho Nadzarillah, Najmatul Jannah Najwa Asnani, Abidah Dyah Nanik Handayani Novera Herdiani, Novera Nur Lailatul Qodriyah Nur Zalsabila Isnaini Nuzula, Fina Firdausi Pratiwi, Viera Nuriza Prayekti, Endah Raden Joko Kuncoroningrat Susilo Rahmawati Fitri Awalia Rahmawati, Lili Susan Risthanti, Reine Risa Rizki Nurmalya Kardina Rohmah, Wardah Rosda Rodhiyana S. P. Edijanto Penulis Safinah Izzatunnisa Salim, Hotimah Masdan Sari, Herliani Rahmania Suprapto Maat Suryandaru, Suryandaru Syafira, Nanda Syafiuddin, Achmad Syinta Nur Isnaini Ulan Sari, Della Citra Uswatun Hasanah Wardah Rohmah Wardany, Nadya Ika Widya Novita Sari Widya Novitasari Wilujeng, Putri Shinta Wulansari, Devyani Wulansari, Devyani Diah Wulansari, Devyani Diah Wuryaningsih, Lucia Endang Yusron Suryonegoro Mushawwir Zain, R.A Wafiqah Aulia