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JFL : Jurnal Farmasi Lampung
Published by Universitas Tulang Bawang
ISSN : 23552506     EISSN : 25984896     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health
The focus of JFL is to become a media for the publication of articles on Pharmaceutical and related practice-oriented subjects in the pharmaceutical sciences, natural medicine and clinic community. The scope of the journal is Pharmaceutical sciences, its research and its application.
Arjuna Subject : -
Articles 157 Documents
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POTENSI EKSTRAK ETANOL DAUN KELAKAI (Stenochlaena Palustris (Burm.f) Bedd) SEBAGAI AKTIVITAS ANTIFUNGI TERHADAP Candida albicans: POTENTIAL ETANOL EXTRACT OF KELAKAI LEAVES (Stenochlaena Palustris (Burm.f) Bedd) AS ANTIFUNGI ACTIVITY AGAINST Candida albicans Wahyudi, Achmad Nur; Soemarie, Yulistia Budianti; Fauzi, Muhammad
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1808

Abstract

Thrush is caused by various factors, one of which is the growth of Candida albicans fungus in the mouth area. Many antifungal drugs available to treat Candida albicans fungal infections are made from synthetic chemicals that have the risk of side effects. The objective of this research is to determine the antifungal activity of ethanol extract of kelakai leaves (Stenochlaena palustris (Burm.) Bedd against Candida albicans. The research process begins with testing the concentration of ethanol extract of kelakai leaves (Stenochlaena palustris (Burm.f.) Bedd by 50%, 55%, 60%, and 65%. In addition, phytochemical screening tests, specific and non-specific parameter tests were carried out. Phytochemical screening results show that ethanol extract of kelakai leaves is positive for alkaloids, saponins, tannins, and flavonoids. The specific parameter test shows that the water soluble extract content and ethanol soluble extract content are 83.3% and 85.7%, respectively. Non-specific parameter tests showed ash content of 0.25%, drying shrinkage of 0.27%, and specific gravity of 0.798 g/mL. The results of the antifungal activity test indicate that ethanol extracts of kelakai leaves at concentrations of 50%, 55%, 60%, and 65% cannot inhibit the growth of Candida albicans fungi. Keywords: Stenochlaena palutris, Candida albicans, Kelakai, Antifungal
UJI AKTIVITAS TABIR SURYA PADA EKSTRAK HERBA SURUHAN (Peperomia pellucida [L.] Kunth) DAN OKTIL METOKSISINAMAT Pratiwi, Inda; Djamil, Ratna; Noor, Siti Umrah
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1844

Abstract

Herba suruhan (Peperomia pellucida [L.] Kunth) is a plant that contains flavonoids, functioning as a sunscreen. Octyl methoxycinnamate (OMC) is a synthetic compound used in cosmetic products as a sunscreen ingredient. The purpose of this study was to determine the sunscreen activity by determining the SPF value of the extract of herba suruhan (Peperomia pellucida [L.] Kunth) with octyl methoxycinnamate singly. Herba suruhan was extracted by UAE method and then calculated the SPF value of herba suruhan extract with concentrations of 0.06%, 0.07%, 0.08%, 0.09% and 0.1% and the SPF value of octyl methoxycinnamate with concentrations of 1%, 2.5%, 5% and 7.5%. The results of SPF values of Chinese betel herb extract with concentrations of 0.06%, 0.07%, 0.08%, 0.09% and 0.1% were 22, 24, 30, 33 and 39 respectively. The SPF values of octyl methoxycinnamate with concentrations of 1%, 2.5%, 5% and 7.5% were 39, 39, 40 and 40 respectively. The highest SPF value of betel herb extract at a concentration of 0.1% is 39 and octyl methoxycinnamate at a concentration of 5% and 7.5% is 40. Keywords: Peperomia pellucida [L.] Kunth, Octyl methoxycinnamate, sunscreen
FORMULASI SEDIAAN SABUN PADAT KOMBINASI EKSTRAK KULIT NANAS (Ananas comosus L.) DAN KULIT DURIAN (Durio zibethinus) TERHADAP Staphylococcus aureus: FORMULASI SEDIAAN SABUN PADAT KOMBINASI EKSTRAK KULIT NANAS (Ananas comosus L.) DAN KULIT DURIAN (Durio zibethinus) TERHADAP Staphylococcus aureus Wahyu Tri Mulyani, Yuli; Sari, Novita; Nurjanah, Siti; Anasis, Annisa Mulia; Harissa, Nola
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1878

Abstract

Staphylococcus aureus bacteria are bacteria that can cause infections. Prevention can be done by cleaning the body with soap. Soap is a skin cleansing preparation made from a saponification process between oil and organic or inorganic bases. Pineapple and durian peel contain active antibacterial compounds, namely alkaloids, flavonoids, saponins, and tannins. This study aims to determine the antibacterial activity of solid soap combined with pineapple peel and durian peel extracts against Staphylococcus aureus. The research method used was a laboratory experimental method with a solid soap formulation combining pineapple peel and durian peel extracts. Solid soap formulations are tested for bacteria using the hole/well method. The formulations used are F0 (soap base), F1 (0 pineapple peel extract and 4% durian peel), F2 (1% pineapple peel extract and 3% durian peel), F3 (2% pineapple peel extract and 2% durian peel), F4 (pineapple peel 3%, durian peel 1%), F5 (pineapple peel extract 4% and durian peel 0%), and a positive control (solid antibacterial bath soap brand x). A solid soap preparation has been made and has fulfilled the requirements for evaluating the quality of soap preparations, including organoleptic tests, homogeneity tests, pH tests, foam height tests, and stability tests. The results of tests on bacteria showed that the F0 inhibition zone was nonexistent, F1 was 9.72 mm, F2 was 11.31 mm, F3 was 11.73 mm, F4 was 12.15 mm, F5 was 10.34 mm, and the positive control was 14.18 mm. The conclusion of this study was that the best formulation with the largest zone of inhibition was at F3 of 13.73 mm with a strong inhibitory response to Staphylococcus aureus. Keyword: Ananas comosus, Antibacterial soap, Durio zibethinus, Staphylococcus aureus  
Optimization of Carbopol 940 Coriander Leaf Extract Gel (Coriandrum sativum L): Analysis of Physical Properties : EFFECT OF CARBOPOL 940 CONCENTRATION ON PHYSICAL PROPERTIES OF CORIANDER LEAF EXTRACT GEL (CORIANDRUM SATIVUM L.) Nugraha, Davit; Rahmah KR, Siti; Wahlanto, Panji; Fawziah, Cindyvia; Yusuf, Anna
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1883

Abstract

Topical gels are widely used because they are convenient to apply, easily absorbed, and have good stability. Carbopol 940 is one of the thickening agents often used in gel formulations because it can produce high viscosity at low concentrations and is compatible with various active ingredients. In gel formulation, the selection of Carbopol 940 concentration is very important to determine physical properties such as viscosity, pH, spreadability, and stability. Coriander leaves (Coriandrum sativum L.) contain bioactive compounds such as flavonoids, tannins, and saponins that have potential as antioxidants and antimicrobials. This study aims to examine the effect of Carbopol 940 concentration on the physical properties of gel containing coriander leaf extract by experimental method with variation of Carbopol 940 concentration in coriander leaf extract gel formulation. The physical properties of the gel, such as viscosity, pH, spreadability, and stability, were tested using physicochemical parameters to evaluate the effect of Carbopol concentration on the quality of the preparation. Coriander leaves (Coriandrum sativum L.) contain bioactive compounds such as flavonoids, tannins, and saponins that have potential as antioxidants and antimicrobials. The results showed that the concentration of Carbopol 940 significantly affected the physical properties of the gel, including viscosity, spreadability, and pH. The conclusion shows that the optimal formulation of Carbopol 940 can produce coriander leaf extract gel with physical properties that meet the requirements of topical drugs. Keywords:  Gel, Coriander Leaf Extract, Formulation, Physical Properties Test
AKTIVITAS ANTIHIPERURISEMIA KOMBINASI EKSTRAK DAUN KERSEN (MUNTINGIA CALABURA L.) DAN DAUN SIRSAK (ANNONA MURICATA L.) TERHADAP TIKUS PUTIH JANTAN: ANTIHYPERURICEMIA ACTIVITY OF EXTRACT COMBINATION OF KERSEN LEAF (MUNTINGIA CALABURA L.) AND SOURSOP LEAF (ANNONA MURICATA L.) ON MALE WHITE RATS Susanti, Laila; Samsuar; Ariawan, M Wahyu; Widiyastuti, Asih; Isbiyantoro; Widodo, Subur
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1908

Abstract

Kersen (Muntingia calabura L.) and soursop (Annona muricata L.) have many properties to cure several diseases, including antihiperurisemia, which is a disorder of purine metabolism in which patients experience increased uric acid levels. This study aimed to examine the antihiperuricemia effect of a combination of kersen leaf extract and soursop in male rats orally. Extraction was carried out by maceration using 70% ethanol. This research is a laboratory experimental study using male white mice as test animals. Data were processed in the form of ANOVA and LSD (Least Significant Difference) test results to compare between groups P0 (normal control), PI (negative control), P2 (Allopurinol 9 mg/Kg BW), P3 (410 and 3.5 mg/Kg BW), P4 (410 and 7 mg/Kg BW), P5 (410 and 10.5 mg/Kg BW), P6 (610 and 3.5 mg/Kg BW), P7 (610 and 7 mg/Kg BW), P8 (610 and 10.5 mg/Kg BW), P9 (910 and 3.5 mg/Kg BW), P10 (910 and 7 mg/Kg BW) ), P11 (910 and 10.5 mg/Kg BW). Giving the test material starting on the 8th to 14th day. On the 15th day blood was taken by slaughtering to measure uric acid levels using a UV-Vis spectrophotometer. On examination of uric acid levels, the administration of beef liver can significantly increase uric acid levels in male rats. and the administration of kersen leaf extract and soursop leaves can significantly reduce uric acid levels in male rats. The administration of kersen leaf extract and soursop leaves for 7 days at doses of 910 and 10.5 mg/Kg BW most effectively reduced uric acid levels in hyperuricemic mice.   Keywords: Hyperuricemia, kersen leaves extract, soursop leaves extract  
HUBUNGAN WAKTU TUNGGU OBAT DENGAN KEPUASAN PASIEN RAWAT JALAN DI INSTALASI FARMASI RUMAH SAKIT IBU DAN ANAK SANTA ANNA 2024: RELATIONSHIP BETWEEN DRUG WAITING TIME AND OUTPATIENT SATISFACTION IN HOSPITAL PHARMACY INSTALLATIONS MOTHER AND CHILD SANTA ANNA 2024 Nopiyansyah; Wahyuni, Novita Tri; Hijrah; Handayani, Kartika; Wahidah, Lilik Koernia
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.2128

Abstract

The waiting time for non-concocted drug services is the period from the patient submitting the prescription to receiving the finished drug with a minimum standar of<30 minutes, while the waiting time for concocted drugs is the period from the patient giving the prescription to the patient receiving the concoction with a period of <60 minutes. This study aims to see how long the waiting time for medication is with patient satisfaction. This study uses an observational research design with a cross sectional approach conducted at the Santa Anna Mother and Child Hospital Bandar Lampung. The sampling technique uses the Accidental sampling method with a total of 100 respondents. Data analysis in this study uses the chi-square testing technique. The results of this study were obtained by respondents of female gender (62%), male (38%), age 17-25 years (27%), 26-35 years (29%), 36-45 years (23%), 46-55 years (15%), 55-65 years (6%), diagnosis of ISPA (34%), dyspepsia (17%), February (17%), hypertension (5%), Antenatal Care (27%). The waiting time for medication is not according to the standard (19%) and the time is not according to the standard (81%), patients feel dissatisfied (20%), feel satisfied (80%). The results of the chi-square test of drug waiting time with patient satisfaction were obtained score (p= 0.000), meaning that Ho was rejected and Ha was accepted, this indicates that there is a relationship between drug waiting time and patient satisfaction. Keywords:  Drug waiting time, patient satisfaction, hospital
PENGEMBANGAN APLIKASI BERBASIS WEB TERAPI UNTUK PENYEDIAAN INFORMASI PELAYANAN OBAT DI KOTA PALU: TERAPI WEB-BASED APPLICATION DEVELOPMENT FOR DRUG SERVICES INFORMATION PROVISION IN PALU CITY Hardani, Muhammad Fakhrul; Hardani, Ririen; M. Zain Gifary; M. Ilham
JFL : Jurnal Farmasi Lampung Vol. 14 No. 1 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v14i1.2064

Abstract

Advancements in technology have been widely adopted across industries, including pharmaceutical services. Numerous online pharmacies have emerged, offering convenience to consumers but unfortunately, to some extent, diminished the role of pharmacists. This study aims to develop a web-based application called TERAPI, an online pharmacy that does not reduce the role of pharmacists. The work includes designing the operational configuration, and the user interface. The development utilizes technologies like Google Sites, third-party applications, embedded code, and artificial intelligence. The process includes programming validation, menu layouting, and database creation.TERAPI provides six features: Drug, Pharmacy, Consultation, Hospital, ICU, and Order. There are six different test cases (TC): TC A01 verifies dashboard accessibility, TC B01 and B02 indicate that users with valid credentials can create an account (Sign Up), and get into the application (Log In). TC C01, C02, and C03 verify the accessibility of menus Drug, Pharmacy, and Consultation. This application follows the standards and regulations of online drug distribution and does not provide prescription and psychotropic drugs due to safety reasons. Keywords:  Application, drugs, pharmacy, service, web
IMPLEMENTASI SISTEM MANAJEMEN LOGISTIK OBAT DI RUMAH SAKIT MITRA SEHAT MANDIRI SIDOARJO`: `IMPLEMENTATION OF A MEDICATION LOGISTICS MANAGEMENT SYSTEM AT MITRA SEHAT MANDIRI HOSPITAL SIDOARJO Priyoherianto, Andri; Iswandi, Iswandi; Fitriany, Erna; Budi L, Deny
JFL : Jurnal Farmasi Lampung Vol. 14 No. 1 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v14i1.2116

Abstract

  The increased availability of medications today has led to a rise in demand for medical services. Drug logistics management in hospitals involves interrelated stages such as planning, procurement, storage, distribution, processing, evaluation, and monitoring. All of these stages require good coordination to function optimally. This study aims to examine the implementation of drug logistics management at the Pharmacy Installation of Mitra Sehat Mandiri Hospital in Sidoarjo using a qualitative descriptive approach with a cross-sectional design. The results show that training has a positive impact on employee performance, particularly in the input component. Adequate budgeting is necessary for purchasing medications and maintaining storage facilities and related equipment. Equipment must meet standards, have proper lighting, and be regularly calibrated. In general, the hospital’s logistics process includes planning through to supervision. Most medications are available as needed, although some may occasionally be out of stock due to supply shortages from distributors. Additionally, some damaged or expired drugs were found, indicating the need for a comprehensive evaluation of drug management to improve its effectiveness and efficiency. Overall, the availability of medications at this hospital is considered to be in accordance with demand. Keywords: Pharmacy Installation, Input and output components, Drug availability, Health services
ANALISIS DRUG RELATED PROBLEMS (DRPs) PENGGUNAAN ANTIPSIKOTIK PADA PASIEN SKIZOFRENIA DI RUMAH SAKIT JIWA PROVINSI LAMPUNG JANUARI-JUNI 2024: DRUG RELATED PROBLEMS (DRPs) ANALYSIS OF ANTIPSYCHOTIC USE IN SCHIZOPHRENIA PATIENTS AT THE MENTAL HOSPITAL OF LAMPUNG PROVINCE JANUARY-JUNE 2024 Hijrah, Hijrah; Wahyuni, Novita Tri; Isbiyantoro, Isbiyantoro; Sari, Wulan
JFL : Jurnal Farmasi Lampung Vol. 14 No. 1 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v14i1.2222

Abstract

Schizophrenia is severe mental disorder that affects an individual’s thought, feelings, and behavior. Antipsychotics are the primary treatment for schizophrenia and used for a long preiod of time which increases the risk of Drug Related Problems (DRPs) and cause ineffective therapeutic results.  The purpose of this study was to analyze the incidience of DRPs on the use antipsychotic in scizhoprenia patients at The Mental Hospital Of Lampung Province January-June 2024. This research study is a descriptive study with purposive sampling technique. The number of samples used was 86 samples of schizophrenia in patients at Mental Hospital Of Lampung Province in January-June 2024.  The results showed that the characteristics of schizophrenia patiens based on gender were 77 men (89,5%) and 9 women (10,5%).  Characteristic based on age are26-35 years old 35 people (40,7%).  The Characteristics of the most patients occupations were not working 68 people (79,1%). The most prevalent kind of schizophrenia patients was paranoid schizophrenia as 82 cases (94,2%).  The most prescribed drugs for schizophrenia patients were risperidone 82 prescriptions, chlorpromazine 70 prescriptions, and trihexyphenidyl 86 prescriptions. The incidence of DRPs in the category of inappropriate drug combinations was 86 cases (100%), drug dose too low was 23 cases (27%), drug dose too high 0%, and inapproprate of drug administration was 0%. The conclusion of this study is the precentage of Drug Related Problems (DRPs) in schizophrenia patients at the Mental Hospital Of Lampung Province is 32%.   Keywords : Antipsychotics, DRPs, Schizophrenia
IDENTIFIKASI KETEPATAN PENGGUNAAN OBAT ANTI EPILEPSI PADA PASIEN EPILEPSI RAWAT JALAN DI RSUD DR. MOEWARDI PERIODE JANUARI - JUNI 2024: THE CORRECT IDENTIFICATION OF A CURE FOR EPILEPSY IN AN OUTPATIENT EPILEPTIC WARD AT DR. MOEWARIN JANUARY - JUNE 2024 Fitriani, Suci; Sakti Pambudi, Risma; Khusna, Khotimatul
JFL : Jurnal Farmasi Lampung Vol. 14 No. 1 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v14i1.2256

Abstract

Epilepsy is a chronic disorder as a result of brain dysfunction that is characterized by repeated seizures. A major therapy for epilepsy was the administration of anti-epileptic drugs (AEDs). AED identification is important in epileptic patients because anti-epileptic drugs are used over a long period of time. The purpose of this study is to understand the precise rate of use of antiepileptic drugs in outpatient epilepsy at Dr. Moewarin January-June 2024. The study USES descriptive methods with data retrieval retrospectively. The instruments used in this study are the patient's medical records. Identify the correct use of drugs in this study using Doxide (meetings of the Indonesian nerve specialist) 2019 and hospital formulations 2024 -2025 with precise criteria of indicative, precise patients, precise drugs and precise doses. Research indicates that the use of anti-epileptic drugs in an outpatient setting at Dr. Moewarin in the January-June 2024 period is the exact rate 100%, exact patients 100%, exact drugs 100%, and exact dosage 94%. Keywords: Epilepsy, precise indications, proper patients, right medication, right dosage.

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