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Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia

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Published by Pengurus Besar Ikatan Dokter Indonesia

ISSN : 20891067 EISSN : 26543796 DOI : http://dx.doi.org/10.47830

Core Subject : Health, Science, Education,

Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

Journal Of The Indonesian Medical Association (JInMA) / Majalah Kedokteran Indonesia (MKI) adalah Jurnal yang berada di bawah naungan Pengurus Besar Ikatan Dokter Indonesia (PB IDI) dan sebagai Kanal InformasiIlmiah di Kalangan Dokter Umum dan Dokter Spesialis serta Profesi Terkait.

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 428 Documents

39 40 41 42 43

Efektivitas Penambahan Latihan Penguatan Ekstremitas Bawah terhadap Peningkatan Kebugaran Kardiorespirasi Calon Jemaah Haji Fahrudin, Muhammad Anang Eko; Wahyudati, Sri; Putri, Rahmi Isma Asmara
Majalah Kedokteran Indonesia Vol 75 No 2 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.2-2025-1472

Introduction: Good health condition of Hajj pilgrims candidate will support the optimal performance of worship and decrease morbidity. One of the important health parameters is cardiorespiratory fitness. Exercise is important for improving cardiorespiratory fitness. The level of participation and implementation of structured training activities among Hajj pilgrims candidate is still lacking. The aim of this study was to determine the effectiveness of additional lower extremity strengthening exercises on the cardiorespiratory fitness of prospective Hajj pilgrims who received walking aerobic training. Method: The research was conducted in Salatiga City in February-March 2023. The research design was a randomized control trial, the subjects were 36 Hajj pilgrims candidate, divided into treatment group (n=18) and control group (n=18). The treatment group was given lower extremity strengthening exercise 2x/week intensity 40-50% 1-RM, 2-4 set, 20 repetition and walking aerobic exercise 30 minutes 5x/week and the control group performed walking aerobic exercise 30 minutes 5x/week. Training was carried out for 6 weeks. Measurement of cardiorespiratory fitness (VO2max) with a 6 minute walk test before and after intervention. Result: There was a statistically significant difference in the mean pre- and post-intervention VO2max values at the treatment group (19.53 ± 4.76; p=0.0002) and the control group (18.36 ± 3.38; p=0.000). The increase of the mean difference/delta VO2max between groups was higher at the treatment group than the control group (4.16 ± 2.03 vs 2.87 ± 1.89; p = 0.031). Conclusion: The addition of lower extremity strengthening exercises to walking aerobics can increase cardiorespiratory fitness higher in hajj pilgrims candidate compared to walking aerobics alone.

Hubungan Antara Asupan Energi dengan Rasio Neutrofil Limfosit pada Pasien Sakit Kritis Purwantini, Dian; Wulandari, Yohannessa; Sunardi, Diana; Sutanto, Krisadelfa; Sinaga, Wina; Andayani, Diyah Eka
Majalah Kedokteran Indonesia Vol 75 No 2 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.2-2025-1760

Introduction: Critically-ill patients experience catabolic stress and inflammatory responses resulting in increased catabolism to meet energy demands. Neutrophil lymphocyte ratio (NLR) is used to assess immune and stress responses. Method: This study was a cross-sectional study of subjects aged ≥18 years admitted to the intensive care unit of Dr. Cipto Mangunkusumo National Central General Hospital and University of Indonesia Hospital. The characteristics of the study subjects included age, gender, nutritional status, diagnosis of ICU admission, protein intake, fat intake, and carbohydrate intake. Bivariate analysis was performed to evaluate the correlation between energy intake and neutrophil-lymphocyte ratio.Result: There were 44 subjects with a median age of 55 years (19-86). Nutritional status based on body mass index (BMI) obtained 31.8% normal nutritional status, 20.5% severe malnutrition, 25% obesity grade 1. The most common diagnoses were surgery and trauma 20.5% of subjects and sepsis 20.5% of subjects. Median RNL was 10.39 (2.51-59.5), energy intake was 10.5 (3-29) kcal/kg BW/day, protein intake was 0.4 (0-1.2) g/kg BW/day, fat intake was 18 (0-29)% and carbohydrate intake was 92 (23-184) g/day.Conclusion: There was no correlation between energy intake and NLR.

Hipotiroidisme Pada Proses Penuaan Dan Estetika Defi, Ratna Shintia
Majalah Kedokteran Indonesia Vol 75 No 2 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.2-2025-1848

Aging is a biological process that affects various bodily functions, with the endocrine system, particularly thyroid hormones, playing a crucial role in this process. Thyroid hormone dysregulation, especially hypothyroidism, commonly found in older adults, can accelerate signs of aging both physiologically and aesthetically. The decline in thyroid gland function leads to reduced thyroid hormone production, resulting in slowed metabolism, dry and rough skin, brittle hair, and decreased skin elasticity. Although the symptoms of hypothyroidism often overlap with common signs of aging, thyroid hormone replacement therapy can help restore bodily function and slow down the aging effects. This study aims to analyze the relationship between thyroid hormone dysregulation, particularly hypothyroidism, and the aging process, as well as its impact on physical appearance. This review shows that treating hypothyroidism can minimize its negative effects on body aesthetics and improve the quality of life in the elderly.

Mengatasi Tantangan Skrining HPV pada Perempuan: Sebuah Kajian Umum Bela, Budiman; Hartono, Soni; Pratiwi, Ekawati Betty; Cahyani, Hesti Pramesti; Widyaningtyas, Silvia Tri
Majalah Kedokteran Indonesia Vol 75 No 2 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.2-2025-1898

Introduction: A major challenge in the success of HPV screening programs is achieving 70% coverage of women aged 30-69. This study conducted a survey to examine the factors influencing the willingness of woman in that age group to actively engage HPV screening program.Method: Socio-demographic data, knowledge levels, cervical cancer screening uptake, and willingness to participate in the government’s routine screening program were collected digitally using cross-sectional study. Factors associated with knowledge, participation, and willingness to engage program measured using logistic regression analysis.Result: Among the 87 eligible respondents, 96.6% had heard about cervical cancer mostly via internet, and 51% categorized as having low level knowledge. The percentage of participants willingness to participate in program was 67.82% below the percentage government target coverage. Factors correlated with willingness included: age group 36-40 (aOR = 1.865, 95% CI = 0.567-6.129) and 41-45 (aOR = 2.93, 95% CI = 0.762-11.272), monthly household expense (aOR = 1.682, 95% CI = 0.684-4.138), having relatives suffer cervical cancer (aOR = 2.764, 95% CI = 0.790-9.672), history of HPV vaccination (aOR = 1.187, 95% CI = 0.593-7.539).Conclusion: Respondent willingness to participate in HPV screening program remains to be improved. Various ways to increase participation in screening programs need to be developed to reach various populations of women.

Peran Gut Microbiome pada Attention Deficit Hyperactivity Disorder (ADHD) Setiani, Ariana; Maharatih, Gusti Ayu
Majalah Kedokteran Indonesia Vol 75 No 3 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.3-2025-1096

Attention deficit hyperactivity disorder (ADHD) is a behavioral disorder, associated with neurodevelopmental disorders in the form of persistent patterns of inattention or hyperactivity and impulsivity that interfere with childhood functioning and development. The prevalence of ADHD is estimated at 3.4% in children and adolescents worldwide.1 In 60-80% of cases, ADHD symptoms persist into adulthood.2

Perbandingan Latihan Hatha Yoga dan Senam Lansia terhadap Kebugaran Kardiorespirasi Lansia Pramudhita, Ardina Nur; Ambarwati, Endang; Putri, Rahmi Isma Asmara
Majalah Kedokteran Indonesia Vol 75 No 3 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.3-2025-1579

Introduction: Cardiorespiratory fitness declines with age. Regular exercise helps enhance an elderly person’s physical capacity, fitness, and overall quality of life. Senam lansia is physical activity that is frequently performed by the elderly population. Though hatha yoga has slower movements than exercise for the elderly, it still incorporates various exercise component. This study was aimed to assess the difference between hatha yoga exercise and senam lansia on cardiorespiratory fitness of the elderly.Methods: This study was a randomized controlled pre- and post-test. The hatha yoga group and the control group were randomly selected with a total of 26 participants. For six weeks, three times a week, participants in the intervention group and control group performed hatha yoga and senam lansia, respectively. The six-minute walk test is used to measure maximum oxygen consumption (VO2 max), a measure of cardiorespiratory fitness.Result: The mean VO2max value was 15.03 ± 2.63 ml/kg/minute in the hatha yoga group and 13.82 ± 2.05 ml/kg/minute in the senam lansia group with significant differences between groups. The increase in VO2 max values before and after the intervention was 1.83 ± 1.15 ml/kg/minute in the hatha yoga group and 1.35 ± 1.04 ml/kg/minute in the senam lansia group with no significant difference between the two groups.Conclusion: Hatha yoga exercises and senam lansia have the similar effect on increasing cardiorespiratory fitness as measured by the 6-minute walk test.

Dampak Kerja Shift dan Tingkat Stres terhadap Kadar Gen Brain-Derived Neurotrophic Factor (BDNF) pada Perawat Selama Pandemi Covid-19 Atthariq; Putri, Maria Eka; Fachri, Muhammad; Akaputra, Risky; Renovaldi, Dede
Majalah Kedokteran Indonesia Vol 75 No 3 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.3-2025-1583

Introduction: The project aims to investigate how the Covid-19 epidemic influenced nurses’ stress levels, shift work, and BDNF mRNA expression. Hospitalized patient numbers in Indonesia were rising sharply during the outbreak. This illness has a major impact on nurses’ levels of weariness and stress, which follow each other. High-stress workers have lower serum levels of brain-derived neurotrophic factor (BDNF). Workload, job conflicts, and sleep difficulties are some of the causes that lead to this stress.Methods: The study was conducted at the Cempaka Putih Islamic Hospital in Central Jakarta, Indonesia, from July to September 2020. The study used an analytical observational approach and a cross-sectional design. The number of nurses who participated in this study was 89 people who were selected using This study included 89 nurses who were recruited using a purposive selection technique based on predetermined inclusion and exclusion criteria. Anthropometric measures and intravenous blood collection were used to gather data for real-time PCR analysis of the BDNF gene mRNA expression.Result: The mean BDNF mRNA expression level was 8.93 ng/mL. Nurses reported work-related stress, with a significant correlation (p less than 0.05) between BDNF mRNA expression, work shift, and stress levels. According to the findings, those with low, moderate, and high stress levels had mean BDNF levels of 11.69, 8.65, and 7.36, respectively. Statistical testing revealed a significant difference (p less than 0.001) in the mean mRNA expression of the BDNF gene across subjects with low, moderate, and high stress levels.Conclusion: During the Covid-19 pandemic, a statistical correlation was found between nurse stress levels, work shifts and low BDNF levels.

Kajian Komprehensif Pichia kudriavzevii: Epidemiologi, Biologi dan Manifestasi Klinis sebagai Parasit pada Manusia Fatril, Ayu Eka; Adawiyah, Robiatul
Majalah Kedokteran Indonesia Vol 75 No 3 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.3-2025-1865

Pichia kudriavzevii previously known as Candida krusei, is a non-conventional yeast commonly found in the environment and widely utilized in the fermentation industry. Besides its industrial benefits, P. kudriavzevii also acts as an opportunistic pathogen that can cause severe infections, particularly in immunocompromised individuals. This study is a literature review analyzing the epidemiology, biology, pathogenicity, immune response and clinical manifestations associated with P. kudriavzevii. Relevant literature was collated from databases such as PubMed, Scopus, and Google Scholar, selected based on article relevance and quality. The review findings indicate that P. kudriavzevii is among the five most common Candida species that infect humans, particularly in patients with compromised immune systems, cancer, hematologic malignancies, diabetes mellitus, and those undergoing prolonged antibiotic or corticosteroid therapy. Biologically, P. kudriavzevii exhibits high tolerance to extreme environmental conditions, possesses biofilm-forming capabilities and demonstrates intrinsic resistance to fluconazole. Infections caused by P. kudriavzevii, reffered to as candidiasis krusei, range from mucocutaneous infections (oral/oropharyngeal candidiasis, vaginal candidiasis, and cutaneous candidiasis) to invasive candidiasis which can be life-threatening. The increasing incidence of P. kudriavzevii infections and its antifungal resistance demand greater attention in developing effective diagnostic and therapeutic strategies. Further studies are essential to elucidate its resistance mechanisms and explore alternative therapeutic approaches for improving clinical management.

Hubungan antara Penggunaan Smartphone pada Malam Hari dan Insomnia pada Remaja di Kota Mataram Amanullah, Mohammad Sany Rosafi; Hunaifi, Ilsa; Diatmika, I Putu
Majalah Kedokteran Indonesia Vol 75 No 3 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.3-2025-1868

Introduction: Smartphone use among adolescents, particularly in Mataram City, West Nusa Tenggara, is highly prevalent. Nighttime smartphone useis associated with delayed sleep onset, as it extends the time adolescents more time to engage in various activities. Several studies have shown that smartphones use can contribute to sleep disturbances, including insomnia. This study aims to investigate the relationship between nighttime smartphone use and insomnia among adolescents in Mataram City.Methods: This study employed a cross-sectional design and included 362 students from Mataram City, selected through non-probability consecutive sampling method. Participants completed questionnaires assessing nighttime smartphone use and insomnia symptoms using Insomnia Severity Index. Data were analyzed using Spearman’s rank correlation test.Result: Of the total sample (44.5% male), the majority were 16 years old (62.4%), enrolled in Grade 11 (82.6%), and most (66.9%) were in the natural science program. The majority of participants were classified as having subclinical insomnia (43.9%), while only 2.5% experienced severe insomnia. The findings revealed a positive correlation between the frequency of nighttime smartphone and insomnia among adolescents (r=0.104; p=0.049).Conclusion: There is a significant relationship between the frequency of nighttime smartphone use and insomnia among adolescents in Mataram City.

Karakteristik Klinis dan Demografi Pasien Infark Miokard Elevasi ST di Siloam Heart Center: A Single Center Study Laksono, Sidhi; Nurbaeti, Putri
Majalah Kedokteran Indonesia Vol 75 No 3 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.3-2025-1887

Introduction: Cardiovascular disease remains the leading cause of death globally, with ST-elevation myocardial infarction (STEMI) posing the highest mortality among acute coronary syndromes (ACS). Early intervention, such as percutaneous coronary intervention (PCI), improves outcomes. Objective: To describe the clinical and demographic profile of STEMI patients in Indonesia and identify risk factors associated with disease severity.Methods: A retrospective descriptive study was conducted on STEMI patients who underwent PCI at a Heart Center Hospital from January to December 2024. Data from electronic medical records were analyzed, including only confirmed STEMI cases with complete documentation.Result: 87 patients were included, most male (92%) and aged over 50 (66.7%). Hypertension (49.4%), smoking (46%), and diabetes mellitus (27.6%) were common comorbidities. Leukocytosis occurred in 86.2%, with universally elevated troponin levels. Despite frequent cardiomegaly on chest X-rays, 46% had preserved ejection fraction on echocardiography. Inferior (34.5%) and anterior (19.5%, 17.2%) infarctions were the most common ECG findings. The left anterior descending (LAD) artery was affected in 85.1%, with three-vessel disease present in 49.4%. Mean door-to-balloon (DTB) time was 86.25 minutes. In Intra-PCI Complications, dissection in 2.3%.Conclusion: STEMI in Indonesia predominantly affects older males with modifiable cardiovascular risk factors. These factors are closely linked to severe coronary involvement, particularly multi-vessel disease.

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Editorial Address Jl. Dr. G. S. S. Y Ratulangie No. 29, Menteng, Jakarta Pusat 10350

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Contact Name
Ferius Soewito

Contact Email
-

Phone
+6221-31937910

Journal Mail Official
jinma_mki@idionline.org

Editorial Address
Jl. Dr. G. S. S. Y Ratulangie No. 29, Menteng, Jakarta Pusat 10350

Location
Kota adm. jakarta pusat,

Dki jakarta

INDONESIA