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Nusantara Science and Technology Proceedings
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Articles 40 Documents
Search results for , issue "The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024" : 40 Documents clear
Scoping Review: Potential of Bekul Fruit (Ziziphus jujube Mill.) as an Antidiabetic Agent in Patients with Type 2 Diabetes Mellitus Windayani, Komang; Dirgahayu, Paramasari; Febrinasari, Ratih Puspita
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4301

Abstract

Diabetes mellitus is a metabolic disorder characterized by high blood glucose (hyperglycemia) caused by damage or abnormalities in insulin production. Pharmacological therapy used as a treatment for diabetes mellitus in some patients has adverse side effects on the body, thus encouraging exploration to use natural ingredients as an alternative therapeutic source in reducing blood glucose. Therefore, a thorough review is needed to summarize scientific data and investigate the potential use of natural ingredients bekul fruit (Ziziphus jujube Mill.) in its role as an antidiabetic agent. This study used a scoping review with 4 databases: Pubmed, ScienceDirect, DOAJ and Google Scholar. The results of the scoping review of 5 scientific articles found that bekul fruit (Ziziphus jujube Mill.) is proven to have bioactive content that is rich in antioxidants such as phenolic/polyphenolic compounds (ferulic acid, caffeic acid, chlorogenic acid), flavonoids (quercetin, rutin, catechin), phytosterols, and inulin which have the potential as antidiabetic agents with different mechanisms of action in reducing blood glucose levels. Conclusion: bekul fruit (Ziziphus jujube Mill.) has the potential to be an alternative nutraceutical diet therapy in patients with diabetes mellitus.
Description of Cadres' Knowledge and Attitudes Towards Massage Therapy in Increasing Body Weight in Stunted Toddlers in Tanjung Riau Village, Batam City Putri, Hariyanda; Laska, Yulinda; Mastikana, Indah; Hariyati, Shapna Lina
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4302

Abstract

Stunting is one of the focuses of nutrition improvement target in the world until 2025. The incidence of Stunting is an impact from insufficient nutritional intake both in terms of quality and quantity, highly of health, or the impact from both. The purpose of this study to know description of knowledge and attitude towards massage therapy to increase weight on stunting toddlers. In research use quantitive research with design one group pre-test post-test, the sample of research use voluntary sampling has done in 6 Integrated Health Post (ITH) at Tanjung Riau Area in Batam City, total sample is 42 respondents. The results of the research is the most of the respondents who have a good knowledge about massage therapy to increase weight on stunting toddlers as many as 14 respondents (33,5%), and very good attitude about massage therapy to increase weight on stunting toddlers as many as 16 respondents (38%). Advice for cadres that should improve about knowledge and attitude towards massage therapy to increasing weight on stunting toddlers.
The Potential of Durian Seed (Durio zibethinus Murr.) as Natural Resources with Antioxidant Activity and Total Flavonoid Content Aisyah, Siti; Harioputro, Dhani Redhono; Nurwati, Ida
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4303

Abstract

Durian is mainly distributed in Southeast Asia and is already famous among Indonesian society. In addition, the nutritional content and unique flavor of the pulp, part of durian fruit such as the seed, peel, roots, and leaves also have many benefits. Durian seeds are known as inedible parts and should disposed of as food waste. However, these are a good source of bioactive compounds. Durian seeds contain bioactive compounds that are antioxidants, including phenolics, flavonoids, and alkaloids. Flavonoids are phenolic compounds which have good benefits for human health. This research aims to analyze the potential antioxidant activity and flavonoid content of durian seed waste. The extraction used ethanol 70%, the antioxidant activity test used a scavenging test to 2,2-diphenyl-1-pycryl-hydrazil (DPPH) radical, and total flavonoid content was determined by the UV-Vis spectrophotometry method. Based on the results, durian seed extract has antioxidant activity of 99.70 µg/ml and total flavonoid content of 23,24±0,39 mgQE/g. Durian seed extract has relatively strong antioxidant activity and contains flavonoids as a bioactive compound. This information is useful for researchers to find bioactive compounds that may be new nutraceuticals for antioxidants, anti-inflammatory, anti-diabetic, and therapeutic functional foods.
Viroinformatic Study of Star Anise (Illicium verum) as Mpro Inhibitor in SARS-CoV-2 Infection Arianto, Steven; Lakoan, Milda Rianty; Arianti, Varda
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4304

Abstract

The spread and infection of SARS-CoV-2 towards the end of 2019 started the COVID-19 outbreak. Additionally, the antiviral medications that are still missing. Spices were among the many traditional medicines used in Indonesia. This research aims to find possible bioactive compounds in star anise with antiviral qualities to treat COVID-19 against SARS-CoV-2 proteases through the in-silico approach. Samples were obtained from the Protein Data Bank (PDB) and PubChem (NCBI, USA). Then, drug-likeness analysis was performed on the SCFBIO web server using the Lipinski rule of five. Additionally, the binding activity and molecular interaction by PoseView web server and PyMol software v2.4.1 (Schrödinger, Inc., USA) were determined by the blind docking approach using PyRx 0.8 software. Using Lipinski's rule of five, the eighty-one bioactive chemicals in star anise were examined to see how similar they were to therapeutic compounds. The molecular docking procedure was then executed using PyMOL and PyRx 0.8 (Virtual Screening Tool) and its interaction with Mpro protein. Methylphenyl has been revealed to have the lowest binding energy for Mpro SARS-CoV-2 and great potential as an inhibitor of SARS-CoV-2 viral replication based on the comprehensive research conducted on these bioactive compounds. However, since the results are only computational, a wet lab study is required for validation. Of 38 drug-like bioactive chemicals of star anise, only methylphenyl has the lowest binding affinity, which can bind and function as inhibitor of the Mpro protease enzyme. A can obstruct the SARS-CoV-2 virus's reproduction. As a result, the SARS-CoV-2 virus cannot assemble its genetic material, capsids, and other body components. Viral replication can be stopped to lower the amount of genetic material copied from the virus.
The Effectiveness of Non-Pharmacological Therapy "Thought Stopping” of Dysmenorrhea In Students at The Hermina Health Institute Hartati, Suryani; Laela, Sri
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4305

Abstract

Students or Adolescent girls usually experience dysmenorrhea, which can interfere with their daily activities. This can be overcome by using non-pharmacological therapy: thought stopping. This study aimed to determine how Thought Stopping therapy impacts dysmenorrhea in students at Hermina Health Institute. This research was conducted through a quasi-experiment with a pre-test design and post-test design with the control group. This research involved 48 respondents and was conducted from January to April 2024. This study used a questionnaire about dysmenorrhea pain and the Numeric Pain Scale (NPS) pain scale. The research results showed that 52% of students aged 18-21 years always experienced dysmenorrhea. They experienced a decrease in pain level from moderate (scale 4) to mild (scale 2) after non-pharmacological therapy: Thought stopping distraction therapy was carried out, with a p-value of 0.038, before and after non-pharmacological therapy: Thought stopping. Nurse's nursing action is non-pharmacological therapy: thought stopping can reduce the level of pain in students Hermina Health Institute as a result of dysmenorrhea. In addition, there was a significant difference between the level of change in pain before and after the procedure. It is hoped that students at Hermina Health Institute can apply non-pharmacological therapy: thought stopping to reduce dysmenorrhea.
Postnatal Complementary Care Training Model for Preeclampsy Rini, Susilo; Soetrisno; Suminah; Andayani, Tri Rejeki
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4306

Abstract

The highest cause of maternal death in Banyumas Regency, Indonesia in 2022 is preeclampsia during the postpartum period (66.7 percent). However, preeclampsia detection is only carried out if there are symptoms or complaints. Complementary therapies provide a new modality for preventing preeclampsia without having to wait for symptoms to appear. A preliminary study showed that 95.31 percent of midwife who applied complementary therapies had not received training. This research aims to develop a Postnatal Complementary Care Preeclampsia training model for midwives. This research is RnD. Analysis stage with in-depth interviews (6 midwives) and FGD (6 stakeholders). At the Design and Development stage, the training model was prepared and validated by four experts. In the implementation phase, training interventions were carried out on 66 midwives and evaluated using different tests. Results: (1) Analysis: it is necessary to strengthen midwife resources with training to improve the care of preeclampsia postpartum; (2) Design, and create a postnatal complementary care preeclampsia training model; (3) Development, V-Aiken's expert assessment results are in the very high category (mean 0.95) shows the model is valid; (4) Implementation, Independent T-test results show the difference in performance (p-value 0.030 < 0.05), Mann Whitney test results also show the difference in competence (p-value 0.000 < 0.05) which is higher in intervention group, (5) Evaluation, Wilcoxon test results showed (P value 0.006<0.05) the training model was proven to reduce the incidence of preeclampsia in postpartum. The Postnatal Complementary Care Preeclampsia training model is feasible and can be applied as a training guide to improve the competency and performance of midwives to reduce the incidence of postpartum preeclampsia
The Influence of the Ability to Read Food Labels on Compliance with Reading Food Product Labels among Nutrition Students of Provinsi Kepulauan Riau Anggraini, Citra Dewi; Rosyidah, Haqqelni Nur; Rizma, Amalina; Herviana; Pratiwi, Siska; Desy
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4307

Abstract

Reading food labels among students is currently important to prevent consume excessive amounts of certain nutrients, resulting in excess nutrition or deficiencies in certain nutrients needed by the body. Substance information obtained from food labels is an important source of nutritional information but is usually underutilized by consumers. The information on food labels helps consumers become savvy about their food choices. This research using cross sectional design. Respondents in this study were students from the students of the nutrition undergraduate study program in Institut Kesehatan Mitra Bunda with a total of 47 respondents. Sample selection was carried out using purposive sampling. The data collection method in this study was through a questionnaire. Respondent’s will fill in the questionnaire given themselves by following the instructions that will be explained before filling out the questionnaire by the data collection team. Data on respondents' ability to read nutritional value information labels was obtained from several multiple choice questions regarding the quantitative information contained in the food labels. It was found that of the 38 respondents who had good ability to read nutritional value information labels, there were 55.3% (21 respondents) who did not comply with reading nutritional value information labels. Then the statistical test results obtained were 0.908. Majority of respondents have good abilities but are not obedient in reading nutritional value information labels. The behavior of reading food labels can be used as a preventive and promotive to maintain health.
Determination of Levels of Phytochemical Compounds (Saponins, Alkaloids, Tannins) In Ripe Fiber Extract of Palmyra Fruit (Borassus flabellifer Linn) Amarduan, Tince Bety; Sari, Yulia; Wasita, Brian
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4308

Abstract

Palmyra fruit (Borassus flabellifer L.) is one of the palm tree family that can be utilized as a source of of food. It also possess numerous benefits in medicinal applications, including secondary metabolites in the form of alkaloids, flavonoids, saponins, tannins, and terpenoids. All of which exhibit antioxidant, anti-inflammatory, and antimicrobial. Therefore, it is imperative to conduct quantitative phytochemical analysis to garner the composition of each compound in Palmyra fruit. This study aims to determine the level of saponins, alkaloids, and tannins in Palmyra fruit fiber extract originating from Werain village, Selaru, West Southeast Maluku. The extraction process was done using the maceration method with 96% ethanol solvent. Method: This study is geared toward quantitative laboratory-scale experiments to determine the sample level. Saponin and alkoloids were analyzed using gravimetry methods while tannins were analyzed using UV-Vis spectrophotometric. Results: it is revealed that saponins level is 1,02%; Alkaloids level is 1,5464; and tannins level is 1,0220%. Conclusion: The presence of saponins is 1,02%; Alkaloids is 1,5464; and tannins is 1,0220%.
The Relationship Between Education, Occupation, and Nutritional Status with Fasting Blood Glucose Levels in Type II Diabetes Mellitus Patients at Jasa Kartini Hospital Tasikmalaya City in 2023 Nurgajayanti, Cendi; Susilawati, Tri Nugraha; Wiboworini, Budiyanti
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4309

Abstract

The World Health Organization states that diabetes mellitus is caused by several contributing factors including age, gender, education, lifestyle, physical activity, obesity, and family history. This study aims to investigate the relationship between education, occupation, and nutritional status, with fasting blood glucose levels in type 2 diabetes mellitus patients at the outpatient department of Jasa Kartini Hospital in Tasikmalaya City in 2023. An analytical observational study with a cross-sectional design was conducted using secondary data from medical records of 210 samples of diabetes mellitus patients from January to December 2023. Simultaneous assessments were made for each variable, namely education, occupation, nutritional status, and fasting blood glucose levels. The analysis results indicate that the relationship between education and fasting blood glucose levels yielded a p-value of 0.032, while the relationship between occupation and fasting blood glucose levels yielded a p-value of 0.029. However, the relationship between nutritional status and fasting blood glucose levels resulted in a p-value of 0.450. There is a relationship between education and fasting blood glucose levels, there is a relationship between occupation and fasting blood glucose levels, and there is no relationship between nutritional status and fasting blood glucose levels.
Taurine Memory Enhancing Activity Against Phenobarbital Induced Male White Mice by Morris Water Maze Methode Juliani, Seri Indah; Mayefis, Delladari; Almahdy A
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4310

Abstract

Memory decline often occurs in every individual. Data in Indonesia in 2010 there were around 7.2% of people with memory decline. Many efforts are made to improve memory. One compound that is beneficial in improving memory is taurine. This compound has several functions including as the development of the central nervous system and as a neuroprotector. Taurine is abundant in humans, mammals, and marine animals. This study aimed to determine whether taurine has memory-enhancing activity in male white mice and to determine the most effective dose (mg/kg BB) of taurine in improving memory in male white mice. The method used in this study is the Morris Water Maze method. Test animals in this study used 25 mice divided into 5 groups. Group 1 is normal, group 2 is a positive control group given encephalon tablets, and the next group is a group given taurine at doses of 10 mg/kgBB, 20 mg/kgBB, and 40 mg/kgBB. Data analysis using One Way Anova followed by Tukey Post Hoc to find out the differences from each test group. The results of this study showed that taurine at a dose of 40 mg/kgBB had a higher percentage of memory enhancers than other doses.

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