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Rina Priastini Susilowati
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Gedung A Lantai 1, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana Jl. Arjuna Utara No. 6, Duri Kepa, Kebon Jeruk, Jakarta Barat, Jakarta 11510
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Jurnal MedScientiae
Published by Universitas Kristen Krida Wacana
ISSN : -     EISSN : 28291166     DOI : https://doi.org/10.36452/jmedscientiae
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya. Tim editorial menerima naskah berupa artikel penelitian, literature dan systematic review, dan laporan kasus. Naskah yang dikirimkan hendaknya belum pernah diterbitkan sebelumnya di jurnal maupun media yang lain dan disiapkan sesuai dengan template atau format yang telah ditentukan. Setiap naskah yang memenuhi kriteria jurnal akan direview oleh pakar yang sesuai (peer reviewer). Jurnal MedScientiae tidak mengenakan biaya selama proses mulai dari penerimaan naskah hingga publikasi. Jurnal MedScientiae terbit 3 kali dalam satu tahun, yaitu pada bulan April, Agustus dan Desember dengan cakupan keilmuan yang telah disebutkan di atas. Edisi pertama jurnal akan diterbikan di bulan Mei tahun 2022 dengan nomor ISSN 2829-1166.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 249 Documents
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Prevalensi dan Hubungan Infeksi Protozoa Usus dengan Kejadian Diare di RSUD Kemayoran Tahun 2020-2021 Sari, Monica Puspa; Pandapotan, Roy Akur; Agustina, Nurul Fitria
Jurnal MedScientiae Vol 3 No 3 (2024): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3464

Abstract

Infeksi protozoa usus masih menjadi permasalahan di dunia, terutama di negara berkembang seperti Indonesia dengan angka prevalensi 10-18%. Infeksi protozoa usus dapat menyebabkan diare pada anak. Tujuan penelitian adalah ingin mengetahui prevalensi dan hubungan protozoa usus pada penderita diare yang dirawat di RSUD Kemayoran Jakarta. Metode penelitian yaitu analitik deskriptif dengan pendekatan cross sectional menggunakan data rekam medik penderita diare pada tahun 2020-2021 di RSUD Kemayoran. Hasil penelitian ini menunjukkan dari 76 responden didapatkan bahwa kejadian diare di RSUD Kemayoran pada tahun 2020 sampai 2021 paling banyak terjadi pada anak laki laki dengan prevalensi protozoa usus (10,5%). Entamoeba histolytica merupakan protozoa usus yang paling sering menyebabkan diare pada anak. Gejala mual ditemukan sebanyak 5,3%, tanpa dehidrasi sebanyak 6,6% dengan lama rawat 3 hari (9,2%). Hasil uji Fisher menunjukkan bahwa terdapat hubungan yang bermakna antara infeksi protozoa usus dengan gejala mual yang timbulkan (p=0,044), terdapat hubungan antara infeksi protozoa usus dengan karakteristik tinja yang cair (p=0,048) dan berlendir (p=0,045). Hasil uji Mann Whitney menunjukkan bahwa terdapat hubungan antara infeksi protozoa usus dengan usia, pekerjaan dan tingkat pendidikan (p=0,000) serta kadar hemoglobin (p=0,013). Kesimpulan terdapat hubungan antara infeksi protozoa usus dengan gejala mual, konsistensi tinja, usia, pekerjaan, tingkat pendidikan dan kadar hemoglobin.
Faktor yang Mempengaruhi Tingkat Kelelahan pada Perawat Rumah Sakit Pemerintah Provinsi DKI Jakarta Winata, Susanty Dewi; Ingkiriwang, Elly; Sutanti, Yosephin Sri; Purnamawati, Purnamawati; Winaktu, Gracia JMT; Berliana, Adisa
Jurnal MedScientiae Vol 3 No 3 (2024): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v313.3466

Abstract

The issue of the quality of work of nurses in hospitals is something that needs attention, especially regarding the level of work fatigue by nurses. Work fatigue is a symptom related to work efficiency, skills and increased anxiety. Research shows that work fatigue has a significant impact on work accidents. This study aims to determine the factors that influence the level of fatigue in nurses in government hospitals. This research is a descriptive analytical research with a cross sectional approach. The population in this study were nurses at government hospitals. In this research, fatigue factors are divided into 3, namely age, gender and length of service. Sampling was carried out using the simple random sampling method. Data collection uses a questionnaire in the form of a Google form. Based on the results, it was found that there was a relationship between factors that influence fatigue and the level of fatigue, p - value <0.005 (0.000).
Caenorhabditis elegans sebagai Model Hewan Penelitian Biologi dan Biomedis Susilowati, Rina Priastini; Santoso, Adit Widodo; Sabini, Jasmine Harumi
Jurnal MedScientiae Vol 3 No 3 (2024): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3467

Abstract

Caenorhabditis elegans is a microscopic nematode, with a transparent body, short life span, self-fertilization ability. C. elegans is easy to be cultured and has been used as an animal model for molecular research, medicine, pharmacology, and toxicology. In addition, C. elegans was the first animal to have its genome completely sequenced and has played a major role in understanding apoptosis and RNA interference. The use of C. elegans as a biological model in environmental toxicology assessments has allowed for the determination of several endpoints. Some of these utilize effects on the biological functions of the nematode and others use molecular markers. Furthermore, C. elegans has enabled the assessment of neurotoxic effects for pesticides and heavy metals, since this nematode has a very well-defined nervous system. Overall, almost every known toxin has been tested in this animal model. In the near future, the knowledge available about the life cycle of C. elegans will allow for more studies on reproduction, transgenerational toxicity for newly developed chemicals and materials, and detailing the signaling pathways involved in the mechanisms of toxicity. C. elegans is an important animal model for research into the identification and understanding of the machinery of nuclear transport. This has helped elucidate biochemical pathways involved in diseases such as obesity, diabetes, and Alzheimer's disease. C. elegans is an excellent animal model for studying aging because of its short lifespan, susceptibility to oxidative stress, and similarity to the human aging process.
Nursing Care for Patients with Suspect Dengue Fever at Private Hospital in Jakarta City Diva Arta Carolina; Ernawati, Ernawati; Silalahi, Malianti; Noviantari, Komang
Jurnal MedScientiae Vol 3 No 3 (2024): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3469

Abstract

Dengue fever is a disease caused by the dengue virus with symptoms: hyperthermia, joint pain, decreased platelets and leukocytes. However, these symptoms also often occur in viral infections in general, so proper assessment is needed in order to provide appropriate care. This case report is a nursing care for a patient with suspected dengue fever. Nursing care is provided by nursing students for 3 days at a private hospital in Jakarta with government health insurance facilities. Data collection was carried out by interviews, physical examination and diagnostic examination. The diagnosis was found: hyperthermia, acute pain, nausea, and risk of bleeding. In making plans, nurses make plans based on the patient's responses and symptoms. During treatment the leukocytes showed leukopenia which indicated a viral infection. Even though platelet values ​​decrease, they never fall below normal values. The nurse educates the patient not to brush his teeth to prevent gum bleeding. The patient was discharged on the third day of treatment with normal platelet values. Platelet values, which are always within normal limits during the treatment period, cannot confirm that the patient has dengue fever. Nursing care is provided based on the response and symptoms that arise in the patient. Regardless of whether the medical diagnosis confirmed is dengue fever, the nursing process is carried out based on the response or symptoms that appear in the patient.
Uji Aktivitas Antibakteri Ekstrak Daun Kelor (Moringa oleifera) Terhadap Staphylococcus aureus Andini, KD Ayu Asti; Dharmawan, Ade; Layanto, Nicolas
Jurnal MedScientiae Vol 3 No 3 (2024): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3473

Abstract

Plants are a source of various types of chemical compounds that have many benefits, one of which is as antibacterial agents. One of the plants known for its antibacterial properties is the moringa leaf (Moringa oleifera). This research aims to determine whether moringa leaves (Moringa oleifera) possess antibacterial activity, as well as to identify the minimum inhibitory concentration and minimum bactericidal concentration of moringa leaf extract against Staphylococcus aureus bacteria. This research method uses the dilution method. The results of the research indicate that moringa leaf extract has antibacterial activity against Staphylococcus aureus at concentrations of 20%, 40%, and 80%. It was found that as the concentration increases, the antibacterial activity inhibiting the growth of Staphylococcus aureus also increases.
The Effectiveness of Pure Honey as Antioxidant and Gastroprotective in Sprague Dawley Rats (Rattus novergicus) Tanny, Sesilia Bella; Sumbayak, Erma Mexcorry; Dewajanti, Anna Maria; Rumiati, Flora
Jurnal MedScientiae Vol 3 No 3 (2024): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3481

Abstract

Gastritis is a condition where inflammation occurs in the surface lining of the stomach which can be caused by several factors, one of which is non-steroidal anti-inflammatory drugs or NSAIDs. The most commonly used NSAIDs are aspirin, aspirin at a dose of 600 mg/kg can cause acute damage to the stomach. Honey with 30 ml/day or the equivalent of 2 tablespoons provides a gastroprotective effect or protection and healing for stomach damage because it contains antioxidants which reduce the level of damage to the stomach. The purpose of this study was to determine the antioxidant and gastroprotective effectiveness of pure honey in Rattus norvegicus Sprague Dawley rats induced by oral aspirin. This study used a laboratory experimental method which examined the effectiveness of pure honey as an antioxidant and gastroprotective for 11 days. The subjects used were 25 Rattus norvegicus. The results showed that based on histopathological scores, administration of 0.5 mL/kgBB honey for 4 days in experimental animals could significantly reduce gastric damage induced by aspirin 600 mg/kgBB. However, when viewed from the results of the data on GSH levels, there was no significant effect of giving honey on GSH levels in experimental animals.  
Infection in Burn Wound Patient Septrilla, Gladys; Arsita, Elli
Jurnal MedScientiae Vol 3 No 3 (2024): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3494

Abstract

Infection is a major cause of increased morbidity and mortality in burns. It is known that about 67% of wound swab cultures are positive for bacterial infection. Burn infection occurs when the skin as the first line of defense is disturbed so that it becomes a good ground for bacterial growth. Literature review by searching through electronic databases such as PubMed, ProQuest, and Google Scholar with the keywords. Bacteria that are often found to cause burn infection are Pseudomonas aeruginosa (24.95%), Staphylococcus aureus (24.05%), Acinetobacter sp (17.09%), and Klebsiella sp (15.19%). Factors causing infection are age, degree of burn, hospitalization of more than 10 days, drug resistance, and inadequate wound management. The most common pathogen causing burn infection is Pseudomonas aeruginosa, because it can grow in a humid environment. The proper use of definitive antibiotics to fight infection is very important. Piperacillin-Tazobactam, Imipenem, Colistin, and Polymyxin B have high sensitivity to gram-negative bacteria, while Vancomycin and Linezolid are effective against gram-positive bacteria and also in treating MRSA.
Characteristics and Histopathological Features of Breast Tumor Patients at RSUD dr. Chasbullah Abdulmadjid Bekasi City 2019-2023 Angeline, Reni; Husseynia Muharrani; Shintia Christina; Freciyana Boedijono
Jurnal MedScientiae Vol 3 No 3 (2024): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3501

Abstract

Globocan data for 2020 in the world, breast cancer cases are in first place with 2,261,419 cases, the death rate is in fifth place with 684,994 people. In Indonesia, in 2020 breast cancer ranks first. In the 2020 Bekasi City health profile data, there were 92 cases (4.8%) of breast lumps/tumors, compared to 2019 was 6.37%, but when compared to 2018, there was an increase in cases of 4.18%. The aim of this study was to find out information on the characteristics and histopathological features of breast tumor patients at RSUD dr. Chasbullah Abdulmadjid Bekasi City in 2019-2023. This research is a descriptive study with a cross-sectional method, using secondary data from anatomical pathology archives. In the study, a total of 488 cases of benign and malignant breast tumors were found, consisting of: 176 cases in 2019, 97 cases in 2020, 77 cases in 2021, 69 cases in 2022, and 69 cases in 2023. Description of tumor incidence Most benign breasts at the age of 20-29 years, location of upper lateral quadrant tumors, clinical diagnosis of benign breast tumors and histopathological type of mammary fibroadenoma. Meanwhile, the description of the incidence of malignant breast tumors is highest at age > 50 years, location of the upper lateral quadrant tumor, clinical diagnosis and histopathological type of invasive ductal carcinoma.
Kontribusi Artificial Intelligent dalam Diagnostik dan Manajemen Penyakit Mata Anugrahsari, Santi; Umboh, Teresa Gracia; Tjandra, Aldo Elyada
Jurnal MedScientiae Vol 4 No 1 (2025): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i1.3557

Abstract

Artificial intelligence (AI) has come a long way since its introduction in the 1950s. In the past few decades, especially with the advent of machine learning (ML) and deep learning (DL), AI has been able to analyze complex data, learn independently, and have made a major impact on the medical field. Ophthalmology has been one of the major beneficiaries of this technology, thanks to its integration with digital techniques such as Optical Coherence Tomography (OCT), fundus photography, and visual field testing. This study was conducted through a comprehensive literature review using major databases, such as PubMed, Scopus, and Google Scholar. Inclusion criteria included publications in the last five years that were relevant to innovations in AI-based diagnostics and management of eye diseases. A total of 25 journals were selected for analysis, providing insight into the current trends in AI applications for ophthalmology. We found that AI has provided efficiencies in the diagnosis, treatment, and management of eye diseases, as well as expanded access to healthcare through telemedicine. However, challenges such as data validation and algorithm standardization require attention. Through cross-disciplinary collaboration and further development, AI has the potential to revolutionize ophthalmology services to be more inclusive and affordable.
Prevalensi Phoria Dan Tropia Pada Anak Usia Sekolah Dasar Di SDN Duri Kepa 16 Pagi dan SDN 17 PG Di Kelurahan Duri Kepa Jakarta Barat Tahun 2024 Lede, Cindy Alfaranti Gracelia; Silaen, Desi Hartati
Jurnal MedScientiae Vol 4 No 1 (2025): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i1.3577

Abstract

This study aims to determine the prevalence of phoria and tropia in elementary school-aged children at SDN Duri Kepa 16 Pagi and SDN 17 PG in Duri Kepa Village, West Jakarta. The research design used was quantitative descriptive with a cross-sectional approach. A total of 601 children were the subjects of this research. Data was collected using an occluder to detect phoria and Tropical disorders in children. The results showed that the prevalence of exotropia was 0.7% at long distances and 0.8% at near distances, and esotropia was 0.3% at long distances and near distances. The prevalence of orthophoria was found in 99% of children. This research provides recommendations that routine checks for visual impairment in children be carried out from an early age

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