cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Rolan Rusli
Contact Email
admin@jurnalfamul.com
Phone
+6282154639509
Journal Mail Official
admin@jurnalfamul.com
Editorial Address
Gedung Administrasi Fakultas Farmasi Universitas Mulawarman, Jalan Penajam, Kampus UNMUL Gn. Kelua, Samarinda, 75119. Indonesia.
Location
Kota samarinda,
Kalimantan timur
INDONESIA
Jurnal Sains dan Kesehatan
Published by Universitas Mulawarman
ISSN : 23030267     EISSN : 24076082     DOI : 10.25026/jsk
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Jurnal Sains dan Kesehatan menerima naskah karya asli (Artikel Penelitian, Artikel Review, dan Studi Kasus), baik eksperimental maupun teoretis, dalam bidang-bidang berikut: Sains dan Kesehatan (Kedokteran, Farmasi, Kesehatan Masyarakat, Keperawatan, Kebidanan, Gizi, dan lain-lain). Tujuan penerbitan Jurnal Sains dan Kesehatan adalah untuk menyediakan informasi ilmiah tentang perkembangan ilmu dan teknologi di bidang Ilmu Pengetahuan dan Kesehatan.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 764 Documents
 73   74   75   76   77 
Efektivitas Penggunaan Analgesik melalui Gambaran Skor NRS pada Pasien Paska Bedah pada Rumah Sakit Tersier di Padang: Effectiveness of Usage Analgesic through NRS Scores in Post-Surgical Patients at a Tertiary Hospital In Padang Nasif, Hansen; Dillasamola, Dwisari; Andini, Airiza Fitri
Jurnal Sains dan Kesehatan Vol. 7 No. 6 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i6.2601

Abstract

Pain is an unpleasant sensory or emotional experience associated with tissue damage. This study aimed to assess the effectiveness of analgesic use through the Numeric Rating Scale (NRS) score in post-surgical patients in the surgical inpatient ward at a tertiary hospital in Padang. The study design was a descriptive study with a cross-sectional approach. Data collection was conducted through structured interviews with patients 24 hours after surgery using the NRS score. The results showed that of the 61 respondents, mild pain was found in 31 patients (50.82%) with an NRS score of 1-3, moderate pain in 26 patients (42.62%) with an NRS score of 4-6, and severe pain in 4 patients (6.56%) with an NRS score of 7-10. The most commonly prescribed analgesic was ketorolac injection. This study showed that even though analgesics had been administered, some patients still experienced moderate to severe pain, indicating that the analgesics were ineffective. Keywords:          pain, drug, analgesic, surgery   Abstrak Nyeri merupakan suatu pengalaman sensoris atau emosional yang tidak menyenangkan dan berhubungan dengan kerusakan jaringan.  Penelitian ini bertujuan untuk menilai efektivitas penggunaan analgesik melalui gambaran skor Numeric Rating Scale (NRS) untuk pasien paska bedah pada ruang rawat inap bedah pada rumah sakit tersier di  Padang. Desain penelitian merupakan suatu  deskriptif study dengan pendekatan cross sectional. Pengambilan data dilakukan melalui  wawancara terstruktur kepada pasien pada 24 jam paska operasi menggunakan skor NRS. Hasil penelitian menunjukkan bahwa dari 61 responden, didapatkan  skor  nyeri ringan pada 31 pasien (50,82%) dengan skor NRS 1- 3, nyeri sedang pada 26 pasien (42,62%) dengan skor NRS 4-6, dan nyeri berat pada 4 pasien (6,56%) dengan skor NRS 7-10. Analgesik yang paling banyak diresepkan yaitu ketorolak injeksi. Penelitian ini menunjukkan bahwa meskipun analgesik telah diberikan, masih terdapat pasien yang mengalami nyeri dengan tingkat sedang hingga berat yang mengindikasikan bahwa analgesik yang diberikan tidak efektif. Kata Kunci:         nyeri, analgesik, NRS, bedah
Sampul Depan, Informasi Editorial, Daftar Isi, Pedoman Penulis, Sampul Belakang: Front Cover, Editorial Information, Table of Content, Author Guideline, Back Cover Editor, Journal
Jurnal Sains dan Kesehatan Vol. 7 No. 6 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i6.2606

Abstract

Peran Pengawas Menelan Obat dalam Meningkatkan Kepatuhan Minum Obat Pasien Tuberkulosis di Puskesmas Kedungwuni I: The Role of Treatment Supporter in Improving Medication Adherence of Tuberculosis Patients at Kedungwuni I Public Health Center Handayani, Novita; Ningrum, Wulan Agustin; Rahmatullah, St.; Permadi, Yulian Wahyu; A’yun, Qurrata
Jurnal Sains dan Kesehatan Vol. 8 No. 1 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i1.2584

Abstract

Pulmonary tuberculosis remains a major health problem in Indonesia, including at the Kedungwuni I Community Health Center, which recorded 114 cases in 2024. Patient adherence to medication is a crucial factor in successful therapy, while the role of the Medication Observer (PMO) is to improve patient discipline. This study aims to analyze the relationship between the role of the PMO and adherence to tuberculosis patients at the Kedungwuni I Public Health Center. The research design used observational analysis with a cross-sectional approach on 45 tuberculosis patients selected by total sampling. Data were collected using a PMO role questionnaire and the MMAS-8 instrument, and analyzed using Spearman's rho test. The results showed that all patients had a PMO, mostly from their families, with high adherence at 62.2%. There was a significant positive correlation between the role of the PMO and medication adherence (r=0.326; p=0.030). The PMO plays a crucial role in improving compliance and supporting the success of the DOTS program. Keywords:          adherence, medication swallowing supervision, tuberculosis   Abstrak Tuberkulosis paru masih menjadi masalah kesehatan utama di Indonesia, termasuk di Puskesmas Kedungwuni I yang mencatat 114 kasus pada tahun 2024. Kepatuhan pasien dalam mengonsumsi obat menjadi faktor penting keberhasilan terapi, sedangkan pendampingan Pengawas Menelan Obat (PMO) berperan dalam meningkatkan disiplin pasien. Penelitian ini bertujuan menganalisis hubungan peran PMO dengan kepatuhan pasien tuberkulosis di Puskesmas Kedungwuni I. Desain penelitian menggunakan observasional analitik dengan pendekatan cross sectional pada 45 pasien tuberkulosis yang dipilih secara total sampling. Data dikumpulkan menggunakan kuesioner peran PMO dan instrumen MMAS-8, dianalisis dengan uji Spearman’s rho. Hasil menunjukkan seluruh pasien memiliki PMO, mayoritas dari keluarga, dengan kepatuhan tinggi sebesar 62,2%. Terdapat hubungan positif signifikan antara peran PMO dan kepatuhan minum obat (r=0,326; p=0,030). PMO berperan penting dalam meningkatkan kepatuhan dan mendukung keberhasilan program DOTS. Kata Kunci:         kepatuhan, pengawas menelan obat, tuberkulosis
Optimasi HPMC dan Carbopol sebagai Polimer dalam Sediaan Tablet Floating Sari Buah Jambu Biji Merah (Psidium guajava L.): Optimization of HPMC and Carbopol as Polymers in Floating Tablets of Red Guava Juice (Psidium guajava L.) Laksono, Wahid Suryo; Saryanti, Dwi; Kusuma, Eka Wisnu
Jurnal Sains dan Kesehatan Vol. 8 No. 2 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i2.2586

Abstract

Red guava (Psidium guajava L.) is a plant rich in bioactive compounds such as flavonoids and vitamin C, which possess antioxidant activity and potential as a therapy for gastric ulcers. One of the innovative dosage forms to enhance therapeutic effectiveness is the floating tablet. This study aimed to develop and optimize a floating tablet formulation from red guava juice using a combination of hydroxypropyl methylcellulose (HPMC) and carbopol as matrix polymers for controlled drug release. Optimization was carried out using the Simplex Lattice Design (SLD) method, with evaluations including granule physical properties (compressibility) and tablet quality tests (weight uniformity, hardness, friability, floating lag time, and total floating duration). Verification of the optimum formula was performed using a one-sample t-test. The optimization results showed the optimum formula with HPMC 49,72 mg and Carbopol 10,27 mg, with a desirability value of 0,598. The physical properties test results showed a floating-lag time of 1,66±0,24 seconds, total floating duration of 9,69±0,00 hours, weight uniformity (CV) of 2,22±0,270 %, tablet hardness of 4,18±0,41 kg, and friability of 0,39±0,19%. Verification results indicated no significant difference between predicted and actual values, confirming the validity of the optimization model. It can be concluded that the combination of HPMC and Carbopol as polymers in the formulation of floating tablets of red guava juice shows potential to be further developed as an oral dosage form with a modified release system. Keywords:          Psidium guajava L., floating tablet, HPMC, Carbopol, optimization   Abstrak Jambu biji merah (Psidium guajava L.) adalah tumbuhan kaya akan senyawa bioaktif seperti flavonoid dan vitamin C yang memiliki aktivitas antioksidan dan berpotensi digunakan sebagai terapi tukak lambung. Salah satu bentuk inovasi sediaan untuk meningkatkan efektivitas terapi adalah tablet floating. Penelitian ini bertujuan untuk mengembangkan dan mengoptimalkan formula tablet floating dari sari buah jambu biji merah dengan kombinasi polimer Hydroxypropyl Methylcellulose (HPMC) dan Carbopol sebagai matriks pengontrol pelepasan obat. Proses optimasi dilakukan menggunakan metode Simplex Lattice Design (SLD), dan evaluasi meliputi uji sifat fisik granul (kompresibilitas) serta uji mutu tablet (kekerasan, total waktu mengapung kerapuhan, keseragaman bobot, dan floating lag time). Verifikasi formula optimum dengan menggunakan uji one sample t-test. Hasil optimasi menunjukkan bahwa formula optimum dengan perbandingan HPMC 49,72mg dan Carbopol 10,27mg dengan nilai desirability 0,598. Hasil uji sifat fisik  tablet dengan floating lag time 1,66±0,24 detik, total waktu floating 9,69±0,00 jam, keseragaman bobot (CV) 2,22±0,270%, kekerasan tablet 4,18±0,41 kg, dan kerapuhan 0,39±0,19%. Hasil verifikasi menunjukkan tidak terdapat perbedaan signifikan antara nilai prediksi dan aktual, menandakan model optimasi valid. Dapat disimpulkan bahwa kombinasi HPMC dan Carbopol sebagai polimer dalam formulasi tablet floating sari buah jambu biji merah, serta berpotensi dikembangkan lebih lanjut sebagai sediaan oral dengan sistem pelepasan termodifikasi. Kata Kunci:         Psidium guajava L., tablet floating, HPMC, Carbopol, optimasi
Efektivitas Daun Torbangun (Coleus amboinicus) dalam Menghambat Pertumbuhan Bakteri Bacillus cereus: The Effectiveness of Torbangun Leaves (Coleus amboinicus) in Inhibiting the Growth of Bacillus cereus Bacteria Kresnapati, I Nyoman Bagus Aji; Kurniawan, Salsabila Yunita; Novitarini, Novitarini
Jurnal Sains dan Kesehatan Vol. 8 No. 1 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i1.2587

Abstract

This study aims to determine the effectiveness of torbangun leaves (Coleus amboinicus) in inhibiting the growth of Bacillus Cereus bacteria. The urgency of research is due to antibiotic resistance from the use of standard antibiotics, so that the potential of the torbangun leaf plant as an antibiotic candidate is needed. This research method is an experimental study with a Post Test Only Control Group Design research design, namely group (-) in the form of ethyl acetate 96%, group (K +) in the form of Ciprofloxacin antibiotics, treatment group 1 in the form of Ethyl Acetate extract of torbangun leaves (EATL) 20%, treatment 2 EATL 40%, treatment 3 EATL 60% and treatment 4 in the form of EATL 100%. The results showed the widest inhibition zone diameter of 35.0 mm in the (+) standard antibiotic group, followed by EATL 100% 21.7 mm and the lowest Group (-) Ethyl Acetate 96% 8 mm. The results of the One Way ANOVA test showed the effectiveness of torbangun leaves in inhibiting the growth of Bacillus Cereus bacteria with a P value <0.001. Based on the Least Significant Difference (LSD) test, EATL was 100% more effective than other concentrations, but not more effective than standard antibiotics (Group +). The conclusion of this study shows the effectiveness of Torbangun leaves (Coleus amboinicus) in inhibiting the growth of Bacillus Cereus bacteria. Keywords:          Antibacterial; Bacillus_cereus; Coleus_amboinicus; Inhibition_Zone   Abstrak Penelitian ini bertujuan mengetahui efektivitas daun torbangun (Coleus amboinicus) dalam menghambat pertumbuhan bakteri Bacillus Cereus. Urgensi penelitian karena adanya resistensi antibiotik dari penggunaan antibiotik standar sehingga di perlukan potensi tanaman daun torbangun sebagai kandidat antibiotik. Metode penelitian ini merupakan penelitian eksperimen dengan rancangan penelitian Post Test Only Control Group Design yaitu kelompok (-) berupa etil asetat 96%, kelompok (K+) berupa antibiotik Ciprofloxacin, kelompok perlakuan 1 berupa ekstrak etil asetat daun torbangun (EATL) 20%, perlakuan 2 EATL 40%, perlakuan 3 EATL 60% dan perlakuan 4 berupa EATL 100%.  Hasil menunjukkan diameter zona hambat terluas sebesar 35,0 mm pada kelompok (+) antibiotik standar, diikuti EATL 100% 21,7 mm dan terendah Kelompok (-) Etil Asetat 96% 8 mm. Hasil Uji One Way ANOVA menunjukkan efektivitas daun torbangun dalam menghambat pertumbuhan bakteri Bacillus Cereus dengan nilai P <0,001. Berdasarkan uji Least Significant Difference (LSD), EATL 100% lebih efektif dibandingkan konsentrasi lain, tetapi tidak lebih efektif dibandingkan antibiotik standar (Kelompok +). Kesimpulan menunjukkan efektivitas Daun Torbangun (Coleus amboinicus) dalam menghambat pertumbuhan bakteri Bacillus Cereus. Kata Kunci:         Antibakteri; Bacillus_cereus; Coleus_amboinicus; Zona_Hambat
Uji Aktivitas Analgesik Topikal Ekstrak Daun Mint (Mentha piperita) dengan Variasi Konsentrasi Pelarut Etanol Menggunakan Metode Tail Flick: Topical Analgesic Activity Test of Mint Leaf Extract (Mentha piperita) with Variations in Ethanol Solvent Concentration Using the Tail Flick Method Sawu, Sirilus Deodatus; Lahardo, Devanus; Wibowo, Wibowo
Jurnal Sains dan Kesehatan Vol. 8 No. 1 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i1.2588

Abstract

Pain is a physiological response due to tissue damage or harmful stimuli that require analgesic therapy. Long-term use of synthetic analgesics carries the risk of side effects, so natural alternatives are needed, one of which is mint leaves (Mentha piperita) which contain menthol as an analgesic compound. The concentration of ethanol in the extraction process is known to affect the content of active compounds and their pharmacological activity. This study aims to evaluate the topical analgesic effect of mint leaf extract gel extracted with 50%, 70%, and 96% ethanol using the tail flick method in white mice (Mus musculus). The gel was applied to the tail of the mice, then pain was induced with hot water at 55±0.5°C. Latency time was recorded at certain observation intervals. The results showed a significant difference in the average latency time between treatment groups compared to the negative control starting at the 30th minute (p<0.05). The 96% ethanol extract gel showed the highest analgesic effect at the 150th minute with a latency time of 9.05±0.34 seconds and analgesic activity of 53.71%. In conclusion, variations in ethanol concentration affect the optimization of the topical analgesic activity of mint leaves. Keywords:          pain, mint leaf, topical analgesic, effectiveness, tail flick   Abstrak Nyeri merupakan respons fisiologis akibat kerusakan jaringan atau rangsangan berbahaya sehingga memerlukan terapi analgesik. Penggunaan analgesik sintetis jangka panjang berisiko menimbulkan efek samping, sehingga diperlukan alternatif berbahan alam, salah satunya daun mint (Mentha piperita) yang mengandung mentol sebagai senyawa analgesik. Konsentrasi etanol dalam proses ekstraksi diketahui memengaruhi kandungan senyawa aktif dan aktivitas farmakologisnya. Penelitian ini bertujuan mengevaluasi efek analgesik topikal gel ekstrak daun mint hasil ekstraksi dengan etanol 50%, 70%, dan 96% menggunakan metode tail flick pada mencit putih (Mus musculus). Gel dioleskan pada ekor mencit, kemudian diinduksi nyeri dengan air panas 55±0,5°C. Waktu latensi dicatat pada interval pengamatan tertentu. Hasil menunjukkan adanya perbedaan signifikan rerata waktu latensi antar kelompok perlakuan dibandingkan kontrol negatif mulai menit ke-30 (p<0,05). Gel ekstrak etanol 96% menunjukkan efek analgesik tertinggi pada menit ke-150 dengan waktu latensi 9,05 ± 0,34 detik dan aktivitas analgesik 53,71%. Kesimpulannya, variasi konsentrasi etanol berpengaruh terhadap optimalisasi aktivitas analgesik topikal daun mint. Kata Kunci:         nyeri, daun mint, analgesik topikal, efektivitas, tail flick
Efektivitas Lilin Aromaterapi Kombinasi Minyak Lavender–Kenanga terhadap Intensitas Nyeri pada Pasien Hipertensi: The Effectiveness of Lavandula latifolia-Cananga odorata Essential Oil Combination in Aromatherapy Candles on Pain Intensity in Patients with Hypertension Muadifah, Afidatul; Tilarso, Dara Pranidya; Prakoso, Jalu
Jurnal Sains dan Kesehatan Vol. 8 No. 1 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i1.2594

Abstract

Headache in hypertensive patients occurs as a result of vascular damage and vasoconstriction, which lead to reduced oxygen supply and increased arterial pressure. These conditions cause blood flow obstruction that may progress to tissue microinfarction and trigger anaerobic metabolism, producing lactic acid that stimulates the brain’s pain centers. This study aims to analyze the effect of aromatherapy candles containing lavender and Cananga odorata essential oils on the reduction of moderate pain intensity in patients with stage 1 hypertension. The study employed a pre-experimental design using a one-group pre–post test approach. The study population consisted of patients experiencing moderate pain due to stage 1 hypertension. Sampling was conducted using simple random sampling with a total of 52 respondents, who were proportionally assigned to four groups: a control group, treatment group 1, treatment group 2, and treatment group 3. The results showed that prior to the intervention, all respondents experienced moderate pain, and following the administration of aromatherapy candles, most respondents reported a decrease to mild pain. An independent test yielded a value of ? = 0.007 (p < 0.05), indicating a significant effect of aromatherapy candle use on the reduction of moderate pain intensity. This study demonstrates that lavender and Cananga odorata aromatherapy candles are effective as a complementary therapy for alleviating pain in hypertensive patients. Keywords:          Aromatherapy Candle, Cananga odorata, Hypertension, Lavandula latifolia, Pain   Abstrak Nyeri kepala pada pasien hipertensi terjadi akibat kerusakan dan penyempitan pembuluh darah yang menyebabkan penurunan suplai oksigen serta peningkatan tekanan arteri. Kondisi ini menimbulkan obstruksi aliran darah yang dapat berlanjut menjadi mikroinfark jaringan dan memicu metabolisme anaerob, sehingga menghasilkan asam laktat yang menstimulasi pusat nyeri di otak. Penelitian ini bertujuan untuk menganalisis pengaruh penggunaan lilin aromaterapi berbahan minyak esensial lavender dan kenanga terhadap penurunan intensitas nyeri sedang pada pasien hipertensi tahap 1. Desain penelitian menggunakan pra-eksperimental dengan pendekatan one-group pre–post test design. Populasi penelitian meliputi pasien dengan nyeri sedang akibat hipertensi tahap 1. Teknik pengambilan sampel menggunakan simple random sampling dengan total 52 responden, yang dibagi secara proporsional ke dalam empat kelompok penelitian: kelompok kontrol, kelompok perlakuan 1, kelompok perlakuan 2, dan kelompok perlakuan 3. Hasil penelitian menunjukkan bahwa sebelum intervensi, seluruh responden mengalami nyeri sedang, dan setelah pemberian lilin aromaterapi sebagian besar responden mengalami penurunan menjadi nyeri ringan. Uji independent test menunjukkan nilai ? = 0,007 (p < 0,05), sehingga dapat disimpulkan terdapat pengaruh signifikan penggunaan lilin aromaterapi terhadap penurunan intensitas nyeri sedang. Penelitian ini menegaskan bahwa lilin aromaterapi lavender dan kenanga efektif sebagai terapi komplementer dalam meredakan nyeri pada pasien hipertensi. Kata Kunci:         Hipertensi, Kenanga, Lavender, Lilin Aromaterapi, Nyeri  
Karakterisasi Minyak Atsiri Daun Patikala (Etlingera elatior (Jack) R.m Smith) Metode Destilasi Air dengan GC-MS: Characterization of Essential Oil from Patikala Leaves (Etlingera elatior (Jack) R.m Smith) by Water Distillation Method with GC-MS Utami, Yuri Pratiwi; Imrawati, Imrawati; Bone, Mahfuzun; Amody, Zahira; Mustarin, Rahmah; Mono, Mono
Jurnal Sains dan Kesehatan Vol. 8 No. 1 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i1.2597

Abstract

Patikala (Etlingera elatior (Jack) R.M.Smith) is one type of plant from the Zingiberaceae family. Patikala leaves contain bioactive compounds such as polyphenols, alkaloids, flavonoids, steroids, saponins, and essential oils. Patikala leaf essential oil has the potential to be an antimicrobial and antioxidant agent. This research aims to characterize the essential oil from patikala leaves. The extraction method used water distillation and was characterized using GC-MS. The research results showed that the characteristics of essential oil obtained by water distillation method included a yield of 0.03%, organoleptic examination had a characteristic odor, was clear yellow in color, and contained active compounds such as Trans-3-caren-2-ol, p-Cymene, 1,3-Cyclopentadiene, dan 2-Cyclopenten-1-one. Based on the research, monoterpenoid essential oil was obtained. Keywords:          Essential oil, Etlingera elatior (Jack) R.M.Smith, Water distillation   Abstrak Patikala (Etlingera elatior (Jack) R.M.Smith) merupakan salah satu jenis tanaman dari suku Zingiberazeae. Daun patikala mengandung senyawa bioaktif seperti polifenol, alkaloid, flavonoid, steroid, saponin dan minyak atsiri. Minyak atsiri daun patikala berpotensi sebagai agen antimokroba dan antioksidan. Penelitian ini bertujuan untuk karakterisasi   minyak atsiri daun patikala. Metode ekstraksi menggunakan  destilasi air dan dikarakterisasi menggunakan GC-MS. Hasil penelitian yang didapatkan karakteristik minyak atsiri metode destilasi air meliputi % rendamen untuk metode sebesar 0,03%, pemeriksaan organoleptik memiliki bau khas, berwarna kuning bening dengan kandungan senyawa aktif yaitu Trans-3-caren-2-ol, p-Cymene, 1,3-Cyclopentadiene, dan 2-Cyclopenten-1-one. Berdasarkan penelitian diperoleh minyak atsiri monoterpenoid. Kata Kunci:         Minyak atsiri, daun patikala, destilasi air
Gambaran Tipe dan Hambatan Pola Asuh Orang Tua pada Anak Berkebutuhan Khusus di Sekolah Luar Biasa Negeri Samarinda: A Description of Parenting Styles and Obstacles Faced by Parents of Children with Special Needs at the State Special School (SLB) Samarinda Dawasoette, Astry Aulia Bahar; Nugrahayu, Eka Yuni; Rahma, Khairunnida
Jurnal Sains dan Kesehatan Vol. 8 No. 1 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i1.2609

Abstract

Children with Special Needs (CWSN) are individuals who experience physical, cognitive, emotional, or social developmental limitations, requiring appropriate parenting and educational support. Parents of Children with Special Needs often face various challenges in the caregiving process, both internal and external. This study aimed to describe parental parenting styles and the barriers encountered in caring for Children with Special Needs at the State Special School (SLB) Samarinda. A descriptive quantitative design was applied using a cross-sectional approach. Data were collected through questionnaires administered to 62 parents of Children with Special Needs, supported by in-depth interviews to enrich quantitative findings. Data analysis was conducted univariately and presented in the form of frequencies and percentages. The results showed that all respondents applied a democratic parenting style. Most parents did not experience significant caregiving barriers; however, internal challenges such as stress, emotional pressure, and impatience were still identified. External barriers were relatively limited, although family instability and time constraints remained potential factors influencing caregiving effectiveness. These findings suggest that, despite the consistent application of democratic parenting, strengthening parental capacity through education and support remains essential to optimize caregiving for children with special needs. Keywords:          Children with Special Needs, Parenting Challenges, Parents, Parenting Styles   Abstrak Anak Berkebutuhan Khusus (ABK) merupakan individu yang mengalami hambatan dalam perkembangan fisik, kognitif, emosional, dan sosial sehingga memerlukan pengasuhan yang sesuai. Orang tua sebagai pengasuh utama sering menghadapi berbagai tantangan dalam proses pengasuhan ABK. Penelitian ini bertujuan untuk menggambarkan tipe pola asuh orang tua serta hambatan yang dialami dalam mengasuh ABK di Sekolah Luar Biasa (SLB) Negeri Samarinda. Penelitian ini menggunakan desain deskriptif kuantitatif dengan pendekatan potong lintang. Data dikumpulkan melalui kuesioner kepada 62 orang tua ABK, serta dilengkapi dengan wawancara mendalam sebagai data pendukung. Analisis data dilakukan secara univariat dengan penyajian dalam bentuk frekuensi, persentase, dan narasi. Hasil penelitian menunjukkan bahwa seluruh responden menerapkan tipe pola asuh demokratis. Sebagian besar orang tua tidak mengalami hambatan pengasuhan yang signifikan. Hambatan yang paling sering ditemukan berasal dari faktor internal, terutama stres dan tekanan emosional, serta hambatan kepribadian. Hambatan eksternal relatif jarang, namun ketidakstabilan keluarga dan keterbatasan waktu tetap berpotensi memengaruhi efektivitas pengasuhan. Temuan ini menunjukkan bahwa meskipun orang tua ABK mampu menerapkan tipe pola asuh demokratis, dukungan edukasi dan penguatan kapasitas orang tua tetap diperlukan untuk mengoptimalkan proses pengasuhan. Kata Kunci:         Anak Berkebutuhan Khusus, Hambatan Pengasuhan, Orang Tua, Tipe Pola Asuh    
Penurunan Hemoglobin Persisten Pascasectio Caesarea pada HELLP Syndrome: Laporan Kasus Tantangan Diagnostik dan Pendekatan Terapi Kortikosteroid: Unresolved Hemoglobin Decline After Cesarean Delivery in HELLP Syndrome: Diagnostic Challenges and the Role of Corticosteroid Therapy — A Case Report Sukmara, Uta Provinsiana
Jurnal Sains dan Kesehatan Vol. 8 No. 1 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i1.2614

Abstract

Placental abruption associated with severe preeclampsia and HELLP syndrome is a critical obstetric condition that may rapidly progress to hematologic complications. We report a 29-year-old woman, gravida 2 para 1, at 21–22 weeks’ gestation, presenting with abdominal pain and vaginal bleeding, with chronic hypertension and obesity. Initial evaluation revealed severe hypertension, anemia, leukocytosis, mild thrombocytopenia, and ultrasonographic intrauterine fetal death, suggesting placental abruption with superimposed preeclampsia and suspected partial HELLP syndrome. Emergency cesarean section under spinal anesthesia confirmed placental abruption intraoperatively. Postoperatively, progressive hemoglobin decline unresponsive to initial transfusion occurred, accompanied by thrombocytopenia and elevated coagulation markers despite relative hemodynamic stability, creating a dilemma between recurrent bleeding and microangiopathic hemolytic anemia. Exploratory relaparotomy under general anesthesia showed no active bleeding source, only diffuse oozing, supporting HELLP syndrome with consumptive coagulopathy. The patient required ICU care with mechanical ventilation and aggressive blood component transfusion for severe anemia. Adjunctive corticosteroid therapy improved. Keywords:          HELLP syndrome; microangiopathic hemolytic anemia; obstetric anesthesiology; placental abruption   Abstrak Solusio plasenta yang disertai preeklampsia berat dan HELLP syndrome merupakan kondisi obstetri kritis yang dapat berkembang cepat menjadi gangguan hematologis dan multisistem yang mengancam nyawa. Dilaporkan seorang perempuan 29 tahun, gravida 2 para 1, usia kehamilan 21–22 minggu, datang keluhan nyeri perut dan perdarahan pervaginam, terdapat riwayat hipertensi kronik dan obesitas. Evaluasi awal menunjukkan hipertensi berat, anemia, leukositosis, trombositopenia ringan, serta ultrasonografi intrauterine fetal death adanya kecurigaan solusio plasenta dan superimposed preeklampsia dd/suspek partial HELLP syndrome. Pasien menjalani sectio caesarea emergensi dengan anestesi spinal, dan temuan intraoperatif solusio plasenta. Pascaoperasi terjadi penurunan hemoglobin progresif yang tidak responsif terhadap transfusi awal, disertai trombositopenia dan peningkatan marker koagulopati, meskipun hemodinamik relatif stabil, menimbulkan dilema antara perdarahan berulang dan anemia hemolitik mikroangiopatik. Re-laparotomi eksploratif tidak menemukan sumber perdarahan aktif, mendukung HELLP syndrome beserta koagulopati konsumtif. Pasien dirawat di ICU dengan ventilasi mekanik akibat anemia berat (Hb 4,7 g/dL). Transfusi komponen darah agresif disertai terapi kortikosteroid memberikan perbaikan klinis dan hematologis bermakna hingga pasien pulih dan dipulangkan. Kata Kunci:         anemia hemolitik; anestesiologi obstetric; HELLP syndrome; mikroangiopatik; solusio plasenta

Page 76 of 77 | Total Record : 764

 73   74   75   76   77 

Filter by Year

2015 2026


Reset
Filter By Issues
All Issue Vol. 8 No. 2 (2026): J. Sains Kes. Vol. 8 No. 1 (2026): J. Sains Kes. Vol. 7 No. 6 (2025): J. Sains Kes. Vol. 7 No. 5 (2025): J. Sains Kes. Vol. 7 No. 4 (2025): J. Sains Kes. Vol. 7 No. 3 (2025): J. Sains Kes. Vol. 7 No. 2 (2025): J. Sains Kes. Vol. 7 No. 1 (2025): J. Sains Kes. Vol. 6 No. 6 (2024): J. Sains Kes. Vol. 6 No. 5 (2024): J. Sains Kes. Vol. 6 No. 4 (2024): J. Sains Kes. Vol. 6 No. 3 (2024): J. Sains Kes. Vol. 6 No. 2 (2024): J. Sains Kes. Vol. 6 No. 1 (2024): J. Sains Kes. Vol. 5 No. 6 (2023): J. Sains Kes. Vol. 5 No. 5 (2023): J. Sains Kes. Vol. 5 No. 4 (2023): J. Sains Kes. Vol. 5 No. 3 (2023): J. Sains Kes. Vol. 5 No. 2 (2023): J. Sains Kes. Vol. 5 No. SE-1 (2023): Spesial Edition J. Sains Kes. Vol. 5 No. 1 (2023): J. Sains Kes. Vol. 4 No. 6 (2022): J. Sains Kes. Vol. 4 No. 5 (2022): J. Sains Kes. Vol. 4 No. 4 (2022): J. Sains Kes. Vol. 4 No. 3 (2022): J. Sains Kes. Vol. 4 No. 2 (2022): J. Sains Kes. Vol. 4 No. SE-1 (2022): Spesial Edition J. Sains Kes. Vol. 4 No. 1 (2022): J. Sains Kes. Vol. 3 No. 6 (2021): J. Sains Kes. Vol. 3 No. 5 (2021): J. Sains Kes. Vol. 3 No. 4 (2021): J. Sains Kes. Vol. 3 No. 3 (2021): J. Sains Kes. Vol. 3 No. 2 (2021): J. Sains Kes. Vol. 3 No. 1 (2021): J. Sains Kes. Vol. 2 No. 4 (2020): J. Sains Kes. Vol. 2 No. 3 (2020): J. Sains Kes. Vol. 2 No. 2 (2019): J. Sains Kes. Vol. 2 No. 1 (2019): J. Sains Kes. Vol. 1 No. 10 (2018): J. Sains Kes. Vol. 1 No. 9 (2018): J. Sains Kes. Vol. 1 No. 8 (2017): J. Sains Kes. Vol. 1 No. 7 (2017): J. Sains Kes. Vol. 1 No. 6 (2016): J. Sains Kes. Vol. 1 No. 5 (2016): J. Sains Kes. Vol. 1 No. 4 (2015): J. Sains Kes. Vol. 1 No. 3 (2015): J. Sains Kes. Vol. 1 No. 2 (2015): J. Sains Kes. Vol. 1 No. 1 (2015): J. Sains Kes. More Issue