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JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL
Published by Universitas Sari Mutiara Indonesia
ISSN : 22708907     EISSN : 22708907     DOI : https://doi.org/10.51544/tekesnos.v7i1
Core Subject : Health, Science, Education, Social, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Education Engineering Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Nursing Physics Public Health Social Sciences
Focus: Jurnal Teknologi Kesehatan dan Ilmu Sosial (TEKESNOS) diterbitkan oleh Program Studi Sistem Informasi Fakultas Sain dan Teknologi Informasi, Ilmu Kesehatan Fakultas Farmasi dan Ilmu Kesehatan serta Ilmu Sosial Fakultas Ilmu Pendidikan Universitas Sari Mutiara Indonesia di Medan sebagai media untuk menyalurkan hasil pemikiran yang mendasari teknologi menjadi hal penting di dalam segala keilmuan, baik dari segi kesehatan dan ilmu sosial. Jurnal TEKESNOS terbangun dari kolaborasi multidisiplin ilmu dalam menghasilkan penelitian dan pengabdian masyarakat pada bidang teknologi berbasis industri 4.0. Scope: Multidisplin ilmu bidang Teknologi, Kesehatan dan Sosial humaniora, ekonomi, kimia, dan displin ilmu lainnya berupa hasil penelitian.
Arjuna Subject : Umum - Umum
Articles 464 Documents
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FORMULASI SEDIAAN MASKER PEEL OFF DARI EKSTRAK ETANOL DAUN NANGKA KUNING (Artocarpus heterophyllus lam) Widya Fitri; Daely, Ruth Christiani N; Sinaga, Arman Bemby; Ermanda, Fhonna Dara
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Background: Jackfruit leaves contain saponins, flavonoids, and tannins that can stimulate the growth of new cells in wounds. The benefits of yellow jackfruit leaves for the skin can smooth the skin, the antioxidant and anti-inflammatory content in jackfruit leaves is very good for warding off free radicals and repairing damaged skin tissue, acne scars, black spots or wounds on the body can quickly disappear. Peel-off mask is a cosmetic preparation for facial care in the form of a gel that is practical and has advantages in its use, namely after drying it can be immediately peeled off for 15-30 minutes. Objective: General purpose: to make a peel-off mask formulation from ethanol extract from yellow jackfruit leaves. Specific purpose: to determine and test the quality of peel-off mask preparations from ethanol extract of yellow jackfruit leaves. Methods: This study used an experimental method. The sample used in this study was yellow jackfruit leaves. Making yellow jackfruit leaf extract by extraction by maceration method using 96% ethanol as solvent. The concentration of the preparation is 2%, 4%, and 6%. Hasil: Penelitian sedian masker peel off yang dihasilkan semuanya homogen, sediaan masker peel off stabil, uji stabilitas selama 4 minggu tidak mengalami perubahan warna, bau dan bentuk, memiliki pH antara F0 7, F1 F2, dan F3 6. perbedaan konsentrasi ekstrak tidak berpengaruh signifikan terhadap daya sebar dengan konsentrasi 2%, 4% dan 6%. Uji sediaan mengering menghasilkan 15-30 menit, daya sebar F0 6,2 cm, F1 6cm, F2 5,6cm dan F3 5,8 cm. Kesimpulan: dari penelitian formulasi sediaan masker peel off dari ekstrak etanol daun nangka kuning dapat diformulasikan sebagai bahan aktif pada sediaan masker peel off.
FORMULASI KRIM ANTI-AGING DARI EKSTRAK EKSTRAK ETANOL KACANG HIJAU (Phaseolus radiatus Roxb. Non-L.) Nurbaya, Siti; Br Brahmana, Nettietalia; Rejekinta Munthe, Alfian; Pangaribuan, Novalina
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Background: green beans are one type of peanut that are widely consumed by communities as functional. The green nut contains a secondary metabolic compound, among them flavonoid, saponin, steroid/triterpenoid, and tannin, which are potent antioxidants.Research goals: for this study, there is an introduction to the new anti-aging activity in green beans ethanol (Phaseolus radiatus Roxb. non-L..). Research methods: this research method USES experimental methods with 5% concentration, 10%, and 15%. Then compared to the availability in the market and blanks. Some tests have been made against availability, including physical qualities of ready cream including homosexual, existing stability observations, pH, viscosity tests of volunteers, and anti-aging activities of volunteers. Results: the results from the study are the result of a stable cream test at room temperature for four weeks. Organoleptic results in Blanko’s formula and control formulas have not undergone any discoloration, changes in smell and phase separation after four-week long storage of ph cream meet good requirements in skin ph, no side effects of irritation and availability of green bean extract cream (Phaseolus radiatus Roxb. Non-L.) can demonstrate anti-aging effectiveness at 15% concentration. Conclusion: research suggests that supple green bean extract cream has an anti-aging activity.
FORMULASI NANOKRIM EKSTRAK DAUN KATUK (Sauropus androgynus L.Merr.) SEBAGAI PELEMBAB KULIT Chandra, Devina; Rohana Sinaga, Taruli; Rudi Aman Manik, Tumpak; Kristiani Aruan, Tina
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Katuk (Sauropus androgynus (L.) Merr.) leaves have benefits for the human body to protect cell structure and work up vitamin C activity. Cream is a semi-solid preparation which contain one or more dissolved medicinal ingredients in a suitable base material and containing not less than 60% water. Nanocream has an easy, comfortable diffusion on the skin area and increases the absorption of active substances on the skin. This research aims to formulate 3% katuk leaf extract as a skin moisturizer in the form of nanocream preparations with a comparison using blanks (without extract) and Citra brand products. This research was conducted by using an experimental method. The research steps are plant identification, simplicity characterization, screening test, the sample was extracted by maceration for 5 × 24 hours using 80% ethanol solvent then the filtrate was evaporated by a vacuum rotary evaporator at approximately 500C for ±5 hours until a thick extract of katuk leaves was produced. The thick extracts of katuk leaves and blanks (without extract) were formulated in Nanocream preparation by using a high-shear emulsification method (high-shear stirring) using a mixer for 8 hours. Then the organoleptic test, homogeneity test, emulsion test, pH test, viscosity test, irritation test by using 6 volunteers with an age range of 20-30 years and humidity test by using 9 volunteers using a skin analyzer from before use to after use for 4 week. The results of the katuk leaf extract nanocream and blank nanocream (without extract) obtained were homogeneous, remained stable, the emulsion type was o/w, the irritation test did not cause skin irritation and the results of the moisture test were the preparation without extract (blank) from 21.3% to 40.1%, the preparation of katuk leaf extract 3% from 21.3% to 40.8% , and stock image products from 22.6% to 38.9%. The results of the analysis showed that the use of katuk leaf extract nanocream gave changes to dry skin conditions for the better and faster increase in water content in the skin so as to obtain a moisturizing effect on the skin.
FORMULASI SEDIAAN FACIAL WASH GEL EKSTRAK ETANOL DAUN AFRIKA (Vernonia amygdalina Del) SEBAGAI PELEMBAB Chandra, Devina; Lifiani, Rialita; Bemby Sinaga, Arman; Wilson Sembiring, Antonius
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

African leaves (Vernonia amygdalina Del) contain flavonoids that can provide antioxidant effectiveness fromflavonoids and also contain vitamins C and E. And its function is to neutralize free radicals. The purpose of this study was to formulate facial wash gel preparations from African leaf extract, as well as to identify and test the safety, quality, and benefits of the formulation preparations. This research method was carried out experimentally. African leaf ethanol extract was obtained by maceration using 96% ethanol extract which was then concentrated with a rotary evaporator at a temperature of 40oC, then formulated in facial wash gel preparations with concentrations of 1% (Formula 1), 3% (Formula 2), and 6% (Formula 3). Evaluation of facial wash gel preparations included organoleptic examination, pH test, homogeneity, stability, viscosity, spreadability, and foaming power. Irritation test and effectiveness test using a skin analyzer on the volunteer's facial skin, the parameters measured included water content and pore size, the treatment was carried out for 4 weeks. The results of this study indicate that the evaluation of facial wash gel preparations is well formulated and stable, African leaf extract is formulated as a facial wash gel that can provide effectiveness on the volunteer's facial skin, namely increasing moisture on the skin and decreasing pore size on the volunteer's facial skin for 4 weeks of use.
FORMULASI SEDIAAN SHAMPO EKSTRAK ETANOL DAUN ADAM HAWA (Rhoeo discolor) SEBAGAI ANTIKETOMBE Ginting, Ferdinand Paulus; Purba, Sondang; Ike Dameria Br Purba, Hana; Farhan, Reza
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Background: Dandruff is a problem that is often experienced which is the role of microorganisms such as fungi. Pityrosporum ovale is a fungus that causes dandruff in hair. One way to increase activity is to make anti-dandruff shampoo preparations from adam hawa leaves which contain anthocyanins flavonoid compounds and leaf chlorophyll pigments that have antimicrobial activity. Methods: This type of research is an experimental study by conducting a preliminary test on the antifungal activity of the extract of the leaves of adam hawa (Rhoeo discolor) and continued with testing the antifungal activity of anti-dandruff shampoo preparations. The shampoo is made with a blank formula and with the best concentration of adam hawa leaf extract in inhibiting the fungus Pityrosporum ovale. Then the stability test was carried out by evaluating several parameters including organoleptic tests, pH tests, viscosity tests as well as high and foam stability tests. Results: The results showed that the leaf extract of adam hawa (Rhoeo discolor) had the best antifungal activity at a concentration of 90% and met the requirements of organoleptic test, pH test, high foam test and viscosity test. The presence of an inhibitory zone activity, the results of testing the antifungal activity of the shampoo preparations of adam hawa leaf extract (Rhoeo discolor) showed that the shampoo preparation with a concentration of 90% had antifungal activity although it was in the weak category and could be used as an anti-dandruff shampoo.
FORMULASI SEDIAAN SAMPO ANTIKETOMBE EKSTRAK DAUN ALPUKAT (Persea americana Mill) DAN UJI AKTIVITASNYA TERHADAP JAMUR Pityrosporum ovale Mainal Furqon; Silitonga, Evawani Martalena; Br Tarigan, Frida Lina; Rini
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Avocado leaves have antifungal activity because they contain chemical compounds. This study aims to determine whether avocado leaf ethanol extract (Persea americana Mill) can be formulated info anti-dandruff shampoo preparations and determine whether avocado leaf ethanol extract ethanol has antifungal activity against pityrosporum ovale. This research is experimental in the form in the form of an organoleptic test, the results were obtained with a liquid form slightly thick with the smell of avocado extract and blackish brown in color the homogeneity test on the 4 preparations was obtained homogeneous. In the Ph test, the ph for F0 7 and FI, F2, and F3 was obtained 6. The foam heights were 11 cm, while at F2 and F2, and F3, it was 9 cm. The stabilility test. Were was no change in the preparation, and for the irritation test there was no change. Allergic to the respondent. Shampoo activity test on the four preparations obtained inhibition zones in shampoo preparations with can be concluded that avocado leaf extract shampoo has antifungal activity against the fungus pityrosporum ovale.
FORMULASI SPRAY GEL MINYAK DAUN NILAM (Pogostemon calbin Benth) DENGAN VARIASI KOSENTRASI KARBOPOL DAN HPMC Julia Susanti; Rosina Sitohang; Lina Br Tarigan, Frida; Yusfarida Laila Zhohrawati, Rosma
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Patchouli leaf oil spray gel formulation has been carried out, patchouli oil is one of the burns treatment. The purpose of this study was to determine whether the formation of a spray gel formulation of patchouli leaf oil with variance of the combination of carbopol 940 and HMPC 0.1%, 0.2%, 0.3% into a spray gel preparation and whether patchouli leaf oil can be used as a spray gel meets the requirements. quality of safety, this research is an experimental study which is carried out by testing organoleptic, homogeneity, viscosity, pH, spraying pattern, adhesive dispersion, stability, and irritation. The results of the spray gel preparations of carbopol 940 concentration variance and HPMC for organoleptic testing there was a cloudy white color change in the Cycling test, while the homogeneity test for all preparations was homogeneous, the viscosity test of the preparation showed that the 0.3% concentration did not meet the requirements, There was no change in the pH test on the preparations, namely neutral pH, tested for spraying patterns and the adhesion met the requirements of the 0.1% and 0.2% formulas. For the stability of the centrifugation there was no separation in the spray gel and for the irritation test there was no allergy in the respondent.
Aktivitas Penghambatan Enzim Protease 6lu7 Virus Sars-Cov-2 Oleh Senyawa Steroid Glikosida Dari Daun Afrika (Vernonia amygdalina Del.) Secara In Silico Mainal Furqon; Cut Masyithah Thaib; N Daely, Ruth Christiani
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 1 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Background: Vernonia amygdalina Del. Isaplant from the Asteraceae family is a small shrub with dark green leaves and leathery bark that grows predominantly in Africa. This plant contains steroidgly cosides, such: as Vernodalin, Vernolide, Vernolepin, Vernomenin, Vernomydin, Vernodalol, Hydroxylvernolide,11,13-dihydroxylvernodalin, 4,15-dihydrovernodalin, 1,2,3,15,11,13,2’,3’, hexahydrovernodalin, dan 1,2,3,15,11,13,2’,3’-octahydro vernodalin. Sesquiterpene Lakton in African leaves (Vernonia amygdalina) have properties, among others, as antimicrobials. Objective:  The purpose of this study was to determine the inhibition of the SARS-CoV-26LU7 protease enzyme by Sesquiterpen Lakton compounds from African leaves using the in-silico tethering method. Method: The in-silicomooring process is carried out using the PLANTS program and visualized using the MOE 2008 program. The protease enzyme was downloaded through the Protein Data Bank (PDB) with code 6LU7. Two-and three-dimensional models were generated using the Marvin Sketch program. The resulting docking value is evaluated as a result of the docking process. Results: The results showed that the protease 6LU7 enzyme tethering of the SARS-CoV-2 virus could provide valid results in-silico. The Sesquiterpen Lakton compounds from Afri can leaves can inhibit the protease enzyme. The docking result is a bletovisualize of the binding amino acids. Conclusion: In this study, it can be concluded that the Sesquiterpen Lakton compounds from African leaves can inhibit the SARS-CoV-2 virus 6LU7 protease enzyme with a docking score close to the docking score of each comparator drug.
Pola Komunikasi Suami Istri Dalam Penyelesaian Masalah Di Awal Masa Pernikahan Evi Enitari Napitupulu; Rachel Mia Lorenza Lumban Toruan; Monika Simanjuntak
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 5 No. 1 (2023): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
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The background of this research is the communication patterns of husband and wife conflict resolution in early marriage. The phenomenon that is of concern is how to resolve conflicts that befall newly married couples which often cause divorce at a relatively young age of marriage. The purpose of this study was to determine openness, empathy, supportive attitude, positivity, equality, communication patterns in resolving marital conflict in the early days of marriage. The research method in this study is descriptive qualitative and life history. Data obtained through in-depth interviews, observation, and literature. The informants interviewed were seven families. Data analysis uses the Miles and Huberman models. The results of this study indicate that some husband and wife are open and do not find it difficult to be open to their partners in discussing the conflicts that occur. However, some husbands and wives find it difficult to open up to their partners because they are worried that the problems will become more complicated if they open up to their partners. In this study, all married couples showed a sense of empathy for their partners so that this could show that their partners wanted to understand and accept the problems that occurred. The existence of a supportive attitude given by husband and wife to their partners can make household problems resolved quickly. The support needed by husband and wife can be in the form of verbal, non-verbal and material support. Positive attitudes in conflict resolution carried out by married couples in this study are willing to give in to their partners and surrender to the problems that occur.
IDENTIFIKASI SIMPLISIA DAN UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN SAWO (Manilkara zapota L) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Mainal Furqon; Martalena Silitonga, Evawani; Juniwati Barus, Darwita; Sihombing, Fransiska
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
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Sawo (Manilkara zapota) is a fruit plant that belongs to the Sapotaceae family. Sapodilla plants are tropical plants that are easily adaptable to various temperatures, rainfall, soil, and soil salinity. This plant has been widely cultivated and used traditionally as medicine. Sapodilla plants are widely cultivated in yards, gardens and are very easy to find in the market. Staphylococcus aureus bacteria are gram positive bacteria, immobile, not spore-forming and capable of forming capsules, cocci-shaped and arranged like grapes, one of the causes of diarrhea is Staphylococcus aureus bacteria. To overcome this disease by providing antimicrobial agents of natural origin that can inhibit the growth of these bacteria. This study was conducted with the aim of knowing the antibacterial activity of the ethanol extract of rambutan seeds with concentrations of 45%, 50%, 55% and 60% against the growth of Staphylococcus aureus bacteria. This research method uses an experimental method, namely to determine the antibacterial activity of ethanol extract from sapodilla leaves against the growth of Staphylococcus aureus bacteria. This research used 96% ethanol as solvent. The test was carried out through several stages including material collection, preparation of simplicia, manufacture of ethanol extract from sapodilla leaf simplicia by maceration and testing of antibacterial activity against Staphylococcus aureus bacteria. Based on the identification of sapodilla leaf simplicia powder, there are trichomes or hair coverings, stomata and calcium oxalate crystals. Phytochemical screening test of the thick extract of sapodilla leaves contains a group of alkaloid compounds, flavonoids, saponins, steroids/triterpenoids and tannins. The results of the antibacterial activity test of sapodilla leaf extract against Staphylococus aureus bacteria had an average inhibitory activity at concentrations of 45% (9.4 mm), 50% (12.2 mm), 55% (14.8 mm) and 60% (16.3mm). As a comparison, Cloramfenocol 30 g was used to produce an inhibitory power of 20,18 mm and the best results obtained were at a concentration of 60% which had an inhibitory power of 16.3 mm

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