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JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL
Published by Universitas Sari Mutiara Indonesia
ISSN : 22708907     EISSN : 22708907     DOI : https://doi.org/10.51544/tekesnos.v7i1
Core Subject : Health, Science, Education, Social, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Education Engineering Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Nursing Physics Public Health Social Sciences
Focus: Jurnal Teknologi Kesehatan dan Ilmu Sosial (TEKESNOS) diterbitkan oleh Program Studi Sistem Informasi Fakultas Sain dan Teknologi Informasi, Ilmu Kesehatan Fakultas Farmasi dan Ilmu Kesehatan serta Ilmu Sosial Fakultas Ilmu Pendidikan Universitas Sari Mutiara Indonesia di Medan sebagai media untuk menyalurkan hasil pemikiran yang mendasari teknologi menjadi hal penting di dalam segala keilmuan, baik dari segi kesehatan dan ilmu sosial. Jurnal TEKESNOS terbangun dari kolaborasi multidisiplin ilmu dalam menghasilkan penelitian dan pengabdian masyarakat pada bidang teknologi berbasis industri 4.0. Scope: Multidisplin ilmu bidang Teknologi, Kesehatan dan Sosial humaniora, ekonomi, kimia, dan displin ilmu lainnya berupa hasil penelitian.
Arjuna Subject : Umum - Umum
Articles 464 Documents
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UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN PORANG (Amorphophallus oncophyllus Prain.) TERHADAP BAKTERI Escherichia coli DAN BAKTERI Salmonella typhi Marpaung, Jon Kenedy; Suharyanisa; Darwita Juniwati Barus; Putri
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Escherichia coli and Salmonella typhi are included in the pathogenic bacteria. These bacteria can cause infectious diarrheal diseases. Porang (Amorphophallus oncophyllus Prain.) leaves contain antibacterial compounds that are effective against bacterial growth. This study aims to determine the antibacterial activity of Porang leaf extract against Escherichia coli and Salmonella typhi bacteria and to determine the difference in antibacterial activity with the use of various concentrations of extracts on bacterial growth. Porang leaf extract was obtained by maceration method using 96% solvent. This test used the paper disc agar diffusion method with concentrations of 10%, 15%, 20%, and 25% against Escherichia coli and Salmonella typhi bacteria, positive control used chloramphenicol, and negative control DMSO, then tested using statistics using the ANOVA method. The results of the study on Escherichia coli bacteria obtained that the concentration and diameter of the inhibition zone with an average of three repetitions were 10% (9.41mm), 15% (11.4 mm), 20% (12.4 mm), 25% (13 .3 mm) and for Salmonella typhi, 10% (12.8 mm), 15% (13.6 mm), 20% (15.5 mm), and 20% (17.5 mm). In the positive control of chloramphenicol, the diameter of the inhibition zone was obtained with an average of three repetitions for each bacterium, namely Escherichia coli (27.5 mm) and Salmonella typhi (29.4 mm) while the DMSO negative control did not show any inhibition. The conclusion of this study showed that Porang leaf extract had activity against Escherichia coli and Salmonella typhi bacteria with strong criteria, seen from the increase in the concentration of the test solution had an increase in the diameter of the growth inhibition zone on bacteria,
PENETAPAN KADAR VITAMIN C SECARA IODIMETRI PADA TOMAT CHERRY KUNING (Solanum lycopersicum Var. Cerasiforme) YANG DIBUDIDAYAKAN SECARA HIDROPONIK Fitri, Widya; Manurung, Kesaktian; Gustiani Tarigan, Yenni
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Vitamin C is a vitamin that is necessary for a healthy body. Vitamin C is one of the water-soluble vitamins and has a strong reducing power. This reducing power of vitamin C is the reason for choosing the method of determining its levels by iodimetry. The purpose of this study was to determine the levels of vitamin C contained in Yellow Cherry Tomatoes (Solanum lycopersicum Var. Cerasiforme) which were hydroponically cultivated and those grown in soil were carried out by iodimetry.This method uses a descriptive method, namely to examine the levels of Vitamin C samples contained in Yellow Cherry Tomatoes (Solanum lycopersicum Var. Cerasiforme) which are cultivated hydroponically and planted in the ground.Based on the results of the analysis carried out by iodimetric titration, the average level of vitamin C in Yellow Cherry Tomatoes cultivated hydroponically was 29,55 ± 1,2854 mg/100 g and the average level in Yellow Cherry Tomatoes grown in soil was 25,09 ± 1,2862 mg/100 g. Based on these results, it can be concluded that the levels of vitamin C in Yellow Cherry Tomatoes that are cultivated hydroponically are higher than the levels of vitamin C grown in the soil due to different growth factors and plant nutrients.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN MANGKOKAN (Polyscias scutellaria. Burm.f) TERHADAP PERTUMBUHAN BAKTERI Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa dan Escherichia coli Syarifah Roslianizar; Natanael Priltius; Rosina Sitohang; Rahmah
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
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Abstract

Indonesia is a tropical country that has a variety of plants, one of which is the succulent plant (Polyscias scutellaria). Mangkukan plants contain compounds of alkaloids, flavonoids, saponins, tannins, glycosides, steroids, polyphenols, fats. The aim of this study was to determine the antibacterial activity of the ethanolic extract of the Mangkukan leaf (Polyscias scutellaria) against the bacteria Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. The tests were carried out through the stages of collecting materials, preparing simplicia, making ethanolic extract of kukukan leaves and testing the inhibitory power of basil leaves against Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli bacteria. The manufacture of ethanolic extract of the leaves of the Mangkokan was carried out by the maceration method using 96% ethanol. Antibacterial activity testing was carried out using the agar diffusion method using disc paper. The results of the study based on the results of phytochemical screening showed that the simplicia and ethanol extract of the Mangkokan leaf contained flavonoids, glycosides, saponins, steroids/triterpenes. Meanwhile, in the antibacterial activity test, the ethanol extract of the Mangkokan Leaf had antibacterial or inhibition zones on these bacteria with different concentrations, such as concentrations of 60%, 80% and 100%. Positive control using chloramphenicol and for negative control using sterile distilled water. The ethanol extract of the Mangkukan leaf has antibacterial activity of Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli.
UJI DAYA ANTI BAKTERI DARI EKSTRAK ETANOL DAUN BANGUN-BANGUN (Coleus ambonicius L.) TERHADAP BAKTERI PENYEBAB JERAWAT (Propionibacterium acnes) Syarifah Roslianizar*; Sembiring, Evarina; Saripati Harianja, Ester; Tamba, Bosdiser
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 1 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Background: Leaves are a plant that is widely used and widely cultivated throughout Indonesia, and has the potential as a traditional medicinal plant that is beneficial for the health of the body. Bangun-bangun leaves have been investigated and are known to contain compounds that are thought to have antibacterial activity, namely flavonoids, and tannins. The bacteria used to test the antibacterial ability of the leaves was Propionibacterium acnes. Objective: The purpose of this study was to determine the antibacterial activity of the ethanolic extract of the leaves of Bangun-bangun against Propionibacterium acnes bacteria. Method: The process of making extracts of the leaves of Bangun-bangun using the maceration method with 96% ethanol as a solvent. The macerate was evaporated until a thick extract of the leaves was obtained. The simplicial powder was characterized and screened for phytochemicals. The concentration treatment groups used were 1%, 2%, and 3%. The test was carried out by the agar diffusion method against the test bacteria using a paper backer, the results were observed in the form of a zone of inhibition and the value of the Minimum Inhibitory Concentration (MIC) was determined. Results: Results Characterization of simplicial powder, including water content, water-soluble extract content, ethanol soluble extract content, total ash content, and acid insoluble ash content were as follows: 7.99%, 24,24%, 24,02%,5,82,%, and 1.24%. The results of the screening of Simplicial powder were positive for containing alkaloids, flavonoids, glycosides, saponins, tannins, and steroids/triterpenoids. The results showed that the ethanol extract of the leaves of Bangun-bangun had an antibacterial activity with the MIC value of the ethanolic extract of the leaves of Bangun-bangun against Propionibacterium acnes at concentrations of 1%, 2%, and 3%, respectively. Conclusion: The ethanolic extract of the leaves of Bangun-bangun has very strong activity as an antibacterial.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN PISANG EMAS (Musa acuminata Colla.) TERHADAP BAKTERI Staphylococcus aureus Suharyanisa; Binsar Sitorus; Yenni Gustiani tarigan; Hestina; Suedy Jordan Nainggolan
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Banana gold (Musa acuminata Colla.) is a type of banana that contains a lot of sugar so that it has a sweeter taste when compared to other types of bananas. So a study was conducted on the test of antibacterial activity of Ethanol extract golden banana leaves (Musa acuminata Colla.) against Staphylococcus aureus bacteria. This study aims to determine the antibacterial activity of ethanol extract of golden banana leaves and find out at what concentrations have the most influence on the inhibitory power of staphylococcus aureus bacteria growth. This study was conducted by extracting Banana Leaves using 96% ethanol by the maceration method, then the extract obtained was made with several concentrations, namely 20, 40, and 80mg/mL. then antibacterial activity testing is carried out by the method of diffusion agar. In ethanol extract against Staphylococcus aureus bacteria with a concentration of 80mg/mL (14.62 ± 0.99) at a concentration of 40mg/mL (14.23 ± 0.70) and at a concentration of 20mg/mL (12.68 ± 0.42). Ethanol extract concentration of 80 mg/mL has a good ability to inhibit the growth of staphylococcus aureus bacteria with an inhibitory zone (14.62 ± 0.99) which is categorized as strong.
UJI AKTIVITAS PERASAN JERUK PURUT (Citrus hystrix) TERHADAP LUKA BAKAR PADA KELINCI DALAM BENTUK SEDIAAN GEL Hutauruk, Dumartina; Sitorus, Binsar; Rudi Aman Manik, Tumpak
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 2 No. 2 (2020): JURNAL TEKNOLOGI, KESEHATAN, DAN ILMU SOSIAL (TEKESNOS)
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Luka bakar adalah kerusakan jaringan yang disebabkan dengan sumber panas. Perasan jeruk purut (Citrus hystrix.) teruji memiliki kandungan saponin, tanin, flavonoid, yang berpotensi sebagai penyembuhan luka bakar. Tujuan penelitian ini adalah mengetahui pengaruh perbedaan konsentrasi perasan jeruk purut dalam sediaan gel terhadap karakteristik fisik gel, aktivitas penyembuhan luka bakar secara makroskopis (diameter luka), dan konsentrasi efektif dari gel perasan jeruk purut. Penelitian dilakukan pada 5 ekor kelinci yang berumur 4 - 6 bulan yang masing-masing punggung kelinci dibagi menjadi 5 kelompok perlakuan. Induksi dilakukan dengan menempelkan lempeng besi panas berdiameter 3cm selama 5 detik. Kelompok perlakuan meliputi F1, F2, F3 gel perasan jeruk purut dengan konsentrasi 15%,20%, 25%, kelompok kontrol negatif (basis gel), dan kelompok kontrol positif gel yang berisi ekstrak placenta bovine dan neomisin sulfat. Pengolesan gel dilakukan satu hari sekali sebanyak 300 mg. Pengamatan dilakukan setiap hari sampai hari ke-14. Hasil statistika uji karakteristik fisik gel, dan aktivitas penyembuhan luka bakar menunjukkan adanya perbedaan signifikan antara kontrol negatif dengan ketiga konsentrasi gel perasan jeruk purut. Gel perasan jeruk purut konsentrasi 25% memiliki aktivitas penyembuhan luka bakar yang setara dengan kontrol positif. Pemberian gel perasan jeruk purut pada kelinci dapat mempercepat proses penyembuhan luka bakar.
UJI AKTIVITAS ANTIOKSIDAN DAN DETERMINASI TOTAL FLAVONOID DAN TOTAL FENOL DARI EKSTRAK BATANG RAMBUSA (Passiflora foetida L.) Monica Suryani; Sondang Purba; Tumpak Rudi Aman Manik; Sarah Anisa
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
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Oxidative stress caused by free radicals can trigger various dangerous diseases, such as cancer, degenerative diseases, cardiovascular disease, and others. Substances that can counteract or prevent these free radicals are antioxidants which are said to have therapeutic value against these diseases. The plant that will be used in this study is Rambusa stem (Passiflora foetida L.) which is useful as a medicine to treat bones, anemia, cancer, lower blood pressure, kidney disorders, and relieve stress. The purpose of this study was to determine the secondary metabolites found in Rambusa stems, and determine the strength of the antioxidant activity of Rambusa stems in trapping free radicals (DPPH). The extraction method was carried out by maceration using 96% ethanol solvent, phytochemical screening included examination of flavonoids, alkaloids, saponins, tannins, and steroids/triterpenoids. The method used to test the antioxidant activity of the ethanol extract of Rambusa stem is the DPPH free radical scavenging method, and the determination of total flavonoid and total phenol levels was carried out by experimental collection and sample processing using UV-Vis spectrophotometry. The results of phytochemical screening showed that the ethanol extract of the Rambusa stem contained flavonoids, alkaloids, tannins, and steroids/triterpenoids. DPPH shows that the ethanol extract of the Rambusa stem has an average IC50 value of 267.974% categorized as very weak. The ethanol extract of the Rambusa stem has an average total flavonoid content of 51.76283 mg QE/g and an average total phenol content of 19.3197296 mg GAE/g.
Aktivitas Antibakteri Minyak Atsiri Buah Andaliman (Zanthoxylum acanthopodium DC) Terhadap Bakteri Streptococcus mutans dan Propionibacterium acne Fitri, Widya; Tarigan, Yenni Gustiani; Silitonga, Evawani Martalena; Telambenua, Fiki julfitra
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 1 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
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Andaliman fruit is a cultivation plant that functions as an antibacterial. Streptococcus mutans is a bacterium that causes dental caries which causes damage to hard tissues. Acne propionibacterium Is a bacterium that causes skin diseases that cause inflammation of tissues associated with immune systems and supports inflammation of acne. Clindamicin is a broad spectrum broad-spectrum bacteriostatic antibiotic that is active against aerobic and anaerobic microorganisms, positive and negative bacteria. Isolation of andaliman fruit essential oil using the air distillation method using a stahl tool. Antibacterial activity test using disc diffusion on MHA media by determining the diameter of the inhibition zone. The concentration of andaliman fruit essential oil used was 2.5%, 5%, 10%, 20% and 40%, with n-hexane p.a solvent and clindamicin concentration 30 μg / ml which was used as a comparison with aquadest solvent. The results showed the diameter of the combined inhibitory zones in Streptococcus mutans bacteria. With a concentration of 2.5% inhibition zone 8.8 mm, inhibition zone 5% 9.0 mm, 10% inhibition zone 10.1 mm, 10% inhibition zone 11.1 mm, 40% 14.5. In acne bacteria Propionibacterium. 2.5% inhibition zone 9.1 mm, 5% inhibition zone 9.2 mm, 10% inhibition zone 10.3 mm, 20% inhibition zone 12.6 mm, 40% 14.1. And clindamicin as a comparison has a 30.6 mm inhibitory zone in acne Propionibacterium bacteria and in Streptococcus mutans. 29.2 mm. From the results of the antibacterial activity test of andaliman essential oil at a concentration of 2.5%, 5%, 10%, 20% and 40%, able to inhibit the growth of Streptococcus mutans and Propionibacterium acne. The results of isolation of Andaliman fruit essential oil by using the Stahl tool are available 4.76% essential oil
UJI DAYA HAMBAT INFUSA BATANG BROTOWALI (Tinospora crispa (L)) TERHADAP PERTUMBUHAN BAKTERI Escherichia coli Suharyanisa; Evarina Sembiring; Ester Saripati Harianja; Sahma Desriani Sinaga
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
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Background: Brotowali stems (Tinospora crispa (L)) contain many chemical compounds that are efficacious in curing various diseases. Brotowali stems (Tinospora crispa (L)) contain bitter compounds (Picroretin), alkaloids, tinocrisposide, saponins, columbine, palmatin, kaemferol, and starch. Escherichia coli (Gram negatitve) is a bacterium that causes diarrhea. Research objectives: The purpose of this study was to determine the inhibitory power of brotowali stem infusion on the growth of Escherichia coli bacteria and to determine the effective concentration of brotowali stem infusion on the growth of Escherichia coli. Research method: This research methode uses an experimental methode of agar diffusion method of agar diffusion method to test the antibacterial and infusion of brotowali stems with concentrations of 25%w/v. 50%w/v, and 75%w/v. Results: The results of this study showed that concentrations of 25%, 50%, 75% of brotowali stem infusion had antibacterial inhibition against the growth of Escherichia coli as indicated by the inhibitory diameters of 7,5mm, 7,93mm, 10mm, respectively. Conclusion:  The conclusion of this study can be concluded that the infusion of brotowali stems (Tinospora crispa (L)) can inhibit the growth of Escherichia coli bacteria.
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Kemangi (Ocimum sanctum L) Sebagai Antibakteri Terhadap Streptococcus mutans Rialita Lifiani*; Rezza Fikrih Utama; Ester Saripati Haria; Rahayu Kartini
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 1 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
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Background: One of the traditional medicinal plants that are widely used by the Indonesian people is the basil plant (Ocimum sanctum L). Which has a role as an antibacterial that can inhibit the growth of bacteria. Objectives: The Purpose of this study was to determine the ability of basil leaf extract (Ocimum sanctum L) to inhibit the growth of Streptococcus mutans bacteria from concentrations of 20%, 40%, 60%, 80% and to determine the effective concentration of antibacterial activity against the growth of Streptococcus mutans bacteria. Method: This research method used the experimental method. Antibacterial activity was tested by diffusion method using disc paper. The ethanol extract of basil leaves was made by maceration method using 96% ethanol as solvent. The concentration of the test solution used was a negative control DMSO, positive control of Chlorhexidine. Result: The results of the phytochemical screening test of basil leaf powder showed the presence of Flavonoid compounds, Steroids/Triterpenoids, tannins, and saponins. The results of the antibacterial activity test showed that the basil leaf extract gave inhibition zones at concentrations of 20%, 40%, 60%, and 80% against Streptococcus mutans bacteria, each of which had an inhibition zone (13,5mm), (16,6mm), (18mm), and (18,9mm) in Chlorhexidine 20,6mm. Conclusion: The conclusion from research results can be concluded that basil leaf extract (Ocimum sanctum L) has anti-Bacterial activity against Streptococcus mutans bacteria.

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