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INDONESIA
Berkala Ilmu Kesehatan Kulit dan Kelamin
Published by Universitas Airlangga
ISSN : 19784279     EISSN : 25494082     DOI : 10.20473
Core Subject : Health, Science,
Immunology & microbiology Public Health
Arjuna Subject : -
Articles 505 Documents
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Correlation between Stress Level and Hair Loss in Students Nadira Sabrina Mufti; Wahyu Lestari; Hajar, Sitti; RM Agung Pranata Kusuma Atmaja
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.9-14

Abstract

Background: Hair loss is one of the most commonly reported problems in dermatology One of the causes of hair loss is high stress levels. The effects of stress can impact hair condition, which in turn can affect appearance. Purpose: This study was to determine the relationship between stress levels and the incidence of hair loss among students at Syiah Kuala University. Methods: This research employed an observational analytic study using approach, utilizing cross-sectional data. The number of subject used in this study was 100 students who were taken by the simple random sampling method. The data analysis used was bivariate analysis to see the relationship between stress levels and the incidence of hair loss. Result: Out of 100 subjects of students with normal, mild, moderate, severe, and very severe stress levels, 59% of them experienced pathological hair loss. By using a significance value of 95%, the relationship between stress levels and the incidence of hair loss in Syiah Kuala University students showed a significance value, or p-value, of 0.024. Conclusion: This study shows that there is a relationship between stress levels and the incidence of hair loss among students at the University of Syiah Kuala.
Factors associated with the Incidence of Occupational Contact Dermatitis of the Hands among Cleaning Service Workers Salwa Azzahra; Akhyar, Gardenia; Satya Wydya Yenny; Raveinal; Ida Rahmah Burhan
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.21-27

Abstract

Background: Occupational contact dermatitis (OCD) is one of the most common occupational diseases worldwide. Occupational diseases in hospitals can affect all workers, including both medical and non-medical personnel, such as cleaning service workers. Purpose: This study aims to determine the factors associated with the incidence of OCD of the hands among cleaning service workers at Dr. M. Djamil Central General Hospital Padang. Methods: This study is an observational analytic study with a cross-sectional design. The sampling technique used was consecutive sampling with 77 total samples. The data were collected by direct interview with a questionnaire instrument. Data analysis used univariate and bivariate analysis with a chi-square test. Result: The results revealed that 28 out of 77 respondents experienced OCD (36.4%). The results of the chi-square test show that the factors of gender (p=0.000) and the use of moisturizers (p=0.017) had a significant relationship with the incidence of OCD. Meanwhile, the factors of age (p=0.725), working period (p=0.492), duration of contact (p=0.862), history of skin diseases (p=0.176), history of atopy (p=0.421), duration of PPE use (p=0.119) did not have a significant relationship with the incidence of OCD. Conclusion: The study concludes that the incidence of OCD of the hands among cleaning service workers at Dr. M. Djamil Central General Hospital Padang is correlated with their gender and their use of moisturizers.
Effect of 8% Purple Sweet Potato Extract Cream on Wrinkle Reduction, Skin Moisture, and Elasticity Laksmi, I Gusti Ayu Agung Mini; Praharsini, I Gusti Ayu Agung; Karmila, I Gusti Ayu Agung Dwi; Rusyati, Luh Made Mas; Suryawati, Nyoman; Winaya, Ketut Kwartantaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.1-8

Abstract

Background: Purple sweet potato has been shown to contain anthocyanins, polyphenols, flavonoids, and tannins that act as antioxidants and have the potential to correct signs of aging in the skin, such as wrinkles, lack of hydration, and pigmentation. Purpose: to known the potential of 8% purple sweet potato extract for wrinkles, moisture, and elasticity. Methods: A one-group experimental study with pre and post-test assessment. The subject is women with photoaging aged 30-45 years. A pre-test was conducted by examining wrinkles using the Glogau scale and a simple A-one scanner, treatment with 8% purple sweet potato extract cream for 6 weeks, and then a post-test at the end of the 6th week to check wrinkles, moisture, and elasticity using a simple A-one scan. Statistical tests using the SPSS program, version 25.0. The analysis performed was descriptive statistical and comparative analysis using a paired T test.  Result: A total of 25 respondents with a mean age ± SD of 38.22 ± 4.23 years, the most Glogau scale in type 2 is 22 respondents (88%), the most sun exposure for 30 minutes per day is 14 respondents (56%). The degree of wrinkles decreased after treatment -4.960±1.353 [95% CI -7.681-(-2.239); P=0.001]. The degree of moisture increased after treatment 8.840±2.990% (95% CI 2.829-14.851; P=0.005. The degree of elasticity increased after treatment 14.840±4.623 (95% CI 5.544-24.136; P=0.002). Conclusion: 8% purple sweet potato extract can reduce the degree of wrinkles, improve the degree of skin moisture, and improve the degree of skin elasticity.
The Relationship between Clean and Healthy Living Behavior and the Incidence of Pityriasis Versicolor in Ambon City Orphanages Wattimury, Marcelino; Manuputty, Amanda Gracia; Hursepuny, Valentine
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.53-58

Abstract

Background: Pityriasis versicolor is a cosmopolitan fungal infection in tropical areas. The revalence is 50%, and it ranks second among Indonesia's most common skin diseases. Pityriasis versicolor was one of the ten worst skin diseases in Maluku Province. It was caused by environmental, behavioral, and public awareness issues, like people who don't follow clean and healthy living habits (CHLB). Purpose: This study aims to determine the relationship between clean and healthy living behaviors and pityriasis versicolor incidence in Ambon City orphanage children in 2024. Methods: This study is conducted by using quantitative research with observational analytical studies through a cross-sectional approach. The sample was taken using total sampling criteria, where population members who met the criteria would be used as a sample. Subsequently, sample of 32 respondents was obtained in this study (84%). Result: The analysis showed that the CHLB level was poor in 22 people (57.9%), and the proportion of pityriasis versicolor incidence was 32 (84.2%). Bivariate analysis showed the significance of the relationship between CHLB and the incidence of pityriasis versicolor with p-value = 0.003. Conclusion: It can be concluded that there is a significant relationship between clean and healthy living behavior and the incidence of pityriasis versicolor in orphanage children in Ambon City. Therefore, it is important to raise awareness about clean and healthy living practices to reduce the incidence of pityriasis versicolor.
Segmental Stiff Skin Syndrome: A Rare Case Report from Indonesia Nurmastuti, Hafidzah; Danarti, Retno; Anggraheni, Radijanti; Arvianty, Intan; Susetiati, Devi Artami; Trisnowati, Niken
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.68-72

Abstract

Background: This paper reports a segmental Stiff Skin Syndrome (SSS) case in a four-year-old girl.  SSS is a rare disease characterized by skin hardening and joint stiffness due to a mutation of the fibrillin-1 (FBN-1) gene encoding the fibrillin protein. The effective therapies for this disease are limited. Case Report: The patient presented with hardened skin and a limping gait.  Clinically, there were hard, hyperpigmented patches with hypertrichosis on the skin of the left femur and left gluteal. The left coxae and left genu joint were in fixed flexion, causing a limping gait. The SSS histology revealed thickened collagen fibers, trapping adipocytes between them, but no inflammatory cells.  The UV-A phototherapy and physiotherapy session resulted in a modest improvement. Discussion: This case's segmental SSS diagnosis was based on clinical and histological findings. Establishing a diagnosis of SSS is a challenge for clinicians because it can resemble other skin disorders, particularly sclerosing diseases. The recommended management for SSS remains limited. In this case, after the UV-A phototherapy and physiotherapy, complaints of hardened skin were said to soften.
The Effect of Alpha Mangostin on The Expression of TGF-β1, SMAD3, Type I Collagen, Proliferation and Migration of Keloid Fibroblasts Asri, Ennesta; Rina Gustia; Indah Indria Sari; Jefrizal Wirman; Yufaz Aidi Mahesa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.41-47

Abstract

Background: Keloid is a process of abnormal collagen thickening during wound healing in skin tissue accompanied by the formation of new blood vessels. Many keloid therapy modalities have been developed but the recurrence rate of those treatment still ranged 1-70%. Herbal plants have been developed for various types of treatment, one of which is for treating keloids. Purpose: The alpha mangostin content in mangosteen peel is known to have antifibrotic properties, further research is needed regarding the administration of alpha mangostin on the process of keloid occurrence. Methods: The investigation was conducted in vitro on phase III keloid fibroblast cells. There were two groups, which divided into the control groups and the treatment groups. The control groups and treatment groups were given alpha mangostin extract in concentrations of 20 μM; the sample of this study was 16. For each group after 24h of the incubation, fibroblast cell proliferation was measured by Microtetrazolium (MTT) assay, fibroblast cell migration was measured by scratch assay, SMAD3 expression was measured after immunocytochemical staining, and type 1 collagen was measured by Enzyme-Linked Immunosorbent Assay (ELISA). The Ethics Committee at the Research Ethics Commission of Faculty of Medicine Andalas University has reviewed this research. Result: Alpha mangostin can reduce the average expression of TGF-β1, SMAD3 expression, type 1 collagen, proliferation, and migration.  . Conclusion: At concentration of 20 μM, alpha mangostin suppressed TGF-β1 expression, SMAD 3, collagen type 1, proliferation, and migration in keloid fibroblast cell.
Correlation between Allergic Rhinitis and History of Infantile Atopic Dermatitis Mutiara Arikah Balqis; Hikmah, Zahrah; Indramaya, Diah Mira; Damayanti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.15-20

Abstract

Background: Atopic march is one of the global health problems that is commonly found in children. The prevalence of allergic rhinitis in Indonesia reaches to 1.5% to 12.4% and continues to increase every year. Allergic reactions can affect all tissues and organs in the body. Some clinical manifestations of allergies are allergic rhinitis, atopic dermatitis, and asthma (atopic march). Atopic march often begins in infancy with the development of atopic dermatitis later in life. Purpose: To analyze the correlation between the prevalence of allergic rhinitis and history of infantile atopic dermatitis in children. Methods: This research used an observational analytic design with a cross-sectional approach. Result: The data were categorized based on a history of atopic dermatitis and the diagnosis of allergic rhinitis. The statistical tests revealed a relationship between the incidence of allergic rhinitis and history of infantile AD in children. The chi-square test yielded a p-value of 0.014 and a contingency coefficient value of 0.213. The odd ratio (OR) value at a confidence level (CL) of 95% and a limit of 1.312 – 6.256 is 2.865, which means that patients who have a history of AD have a 2.8 times higher risk of experiencing AR. Conclusion: The conclusion of this study is that there is a correlation between the incidence of allergic rhinitis and history of infantile atopic dermatitis.
The Influence of Social Media on Self-Medication and Treatment of Acne Vulgaris Butar Butar, Agatha Uli Angelica; Paramita, Deryne Anggia; Putri Amelia; Panggabean, Yoan Carolina
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.48-52

Abstract

Background: With the advancement of technology, access to information about acne vulgaris has become easier. Social media has become a key platform for influencers and doctors to educate the public about acne, which often leads acne sufferers to use social media as a reference for understanding the condition and treatment options. As a result, many individuals choose to practice self-medication based on information obtained from social media. Purpose: This study aims to examine the impact of social media on self-medication and the treatment of acne vulgaris. Methods: This is an analytical cross-sectional study conducted among high school students. The sample was selected using consecutive sampling. Data was collected through a questionnaire that assessed social media usage, self-medication practices, and treatment outcomes. Result: Among the 92 respondents who participated in this study, the following results were found: 18 respondents had a high level of social media usage, 54 respondents had a moderate level, and 20 respondents had a low level. In addition, 64 respondents expressed interest in self-medication, while 28 respondents were not interested in self-medication. The results of the acne treatment of 64 people interested in self-medication showed that eight people had significant improvement in self-medication results, 52 people had slight improvement, and four people had no improvement. The bivariate analysis shows that social media influences self-medication but does not affect treatment outcomes. Conclusion: Social media influences self-medication but does not affect the treatment outcomes of acne vulgaris.
Profile of Transepidermal Water Loss in Non-Atopic Dermatitis and Atopic Dermatitis in Indonesian Adults Damayanti; Anggraeni, Sylvia; Ayu Umborowati, Menul; Farah Adiba, Asmahan; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.28-33

Abstract

Background: Atopic dermatitis (AD) is a recurrent and chronic inflammatory skin disease affecting the quality of life and productivity of individuals. Several studies have reported the profile of transepidermal water loss (TEWL) in AD patients, however, there is either no data or very limited data on TEWL values in normal skin or in non-atopic individuals. Purpose: This study aims to update of the available evidence about TEWL values in healthy (non-AD) adults and AD patients, especially in Indonesia. Methods: This analytic study involved 37 non-AD subjects and 37 subjects with AD. TEWL measurements were assessed on the volar side of the left forearm. Result: The mean values in the non-AD group were 5.61 ± 3.85, while the mean values in the AD group were 18.07 ± 4.88. There is a significant difference in TEWL ​​values between the groups with non-atopic dermatitis and atopic dermatitis (p<0.001). Conclusion: TEWL value is significantly higher in AD patients compared to non-AD  individuals, indicating a compromised skin barrier function in AD. The consistent results across populations and geographic regions support the utility of TEWS as a reliable measure of AD severity, which can help clinicians customize treatment plans to meet the needs of each patient.
Immunodermatology: at a glance Prakoeswa, Flora Ramona Sigit; Awanis, Ghina Shabrina; Sari, Winda Atika; Pramuningtyas, Ratih
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 2 (2025): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.2.2025.130-141

Abstract

Background: Immunodermatology is a medical specialty specializing in detecting and treating skin conditions induced by a compromised immune system response. Each cellular element of the skin undergoes a unique developmental process and serves a specific function within the skin. Many disorders affecting epithelial organs, including the skin, mucous membranes, digestive tract, and respiratory tracts, require immunodermatological testing for diagnosis and treatment. Immunodermatology, a field at the intersection of dermatology and immunology, continues to evolve, with new research being published annually. Purpose: This review aims to summarize the foundational principles of immunodermatology, current diagnostic approaches, and selected immune-mediated skin disorders. Review: There are numerous dermatological conditions related to immunodermatology. Advances in immunology and dermatology have enhanced our understanding of the skin as an active immune organ. Immunodermatology encompasses a wide range of diseases involving both innate and adaptive immunity. Despite growing research, many aspects remain under investigation. Conclusion: The skin’s immunological function could be viewed as a complex and multifaceted interplay between signal processing and defense reactions. Immunodermatology continues to expand with ongoing innovations in diagnostics and therapeutics, highlighting its importance in future clinical and research developments.

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