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All Journal Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Pharmaceutical Science and Technology Majalah Obat Tradisional Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Syntax Literate: Jurnal Ilmiah Indonesia JSFK (Jurnal Sains Farmasi & Klinis) JURNAL FARMASI GALENIKA AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Ilmiah Farmasi Farmasyifa Science Midwifery Current Research on Biosciences and Biotechnology Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Jurnal Abdimas Kartika Wijayakusuma Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Kesehatan Bakti Tunas Husada Kartika : Jurnal Ilmiah Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Galenika Sasambo: Jurnal Abdimas (Journal of Community Service)
Hasimun, Patonah
Fakultas Farmasi, Universitas Bhakti Kencana, Bandung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Science Midwifery

 1 
The role of honey, curcuma, and black cumin supplements in overcoming stunting on the adaptive immune system Sabarudin, Cecep; Hasimun, Patonah; Kusriani, Herni; Zuniarto, Ahmad Azrul; Pandanwangi, Siti; Fatmawati, Eva; Afief, Arief R.; Sodik, Jajang Japar
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2185

Abstract

Stunting is strongly associated with impaired immune function, as chronically malnourished children tend to have weaker immunity and are more vulnerable to infection. This study aimed to examine the effect of temulawak–black cumin herbal honey on the adaptive immune system in stunted children. A quasi-experimental one-group pre-test and post-test design was used. The findings showed that the intervention significantly increased height-for-age (TB/U) in the treatment group compared to the control group (p = 0.014). Weight-for-age (BB/U) also rose significantly within the treatment group (p = 0.013), but no significant difference was found relative to the control group (p = 0.192). The supplement significantly elevated IgM levels in the treatment group (p = 0.001), though again without a significant difference from the control (p = 0.546). CD4 concentration decreased in the treatment group (p = 0.003), but the change was not significantly different from the control (p = 0.682). In conclusion, temulawak–black cumin herbal honey can improve nutritional status and enhance adaptive immunity by increasing IgM levels, although it does not raise CD4 levels and instead slows CD4 decline. However, its effectiveness in increasing IgM and CD4 concentrations compared to controls is not significant.
The role of honey, curcuma, and black cumin supplements in overcoming stunting on the adaptive immune system Sabarudin, Cecep; Hasimun, Patonah; Kusriani, Herni; Zuniarto, Ahmad Azrul; Pandanwangi, Siti; Fatmawati, Eva; Afief, Arief R.; Sodik, Jajang Japar
Science Midwifery Vol 13 No 5 (2025): December: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2185

Abstract

Stunting is strongly associated with impaired immune function, as chronically malnourished children tend to have weaker immunity and are more vulnerable to infection. This study aimed to examine the effect of temulawak–black cumin herbal honey on the adaptive immune system in stunted children. A quasi-experimental one-group pre-test and post-test design was used. The findings showed that the intervention significantly increased height-for-age (TB/U) in the treatment group compared to the control group (p = 0.014). Weight-for-age (BB/U) also rose significantly within the treatment group (p = 0.013), but no significant difference was found relative to the control group (p = 0.192). The supplement significantly elevated IgM levels in the treatment group (p = 0.001), though again without a significant difference from the control (p = 0.546). CD4 concentration decreased in the treatment group (p = 0.003), but the change was not significantly different from the control (p = 0.682). In conclusion, temulawak–black cumin herbal honey can improve nutritional status and enhance adaptive immunity by increasing IgM levels, although it does not raise CD4 levels and instead slows CD4 decline. However, its effectiveness in increasing IgM and CD4 concentrations compared to controls is not significant.
Preliminary study of blood pressure and arterial stiffness monitoring using the niva device (non-invasive vascular analyzer) Avianningsih, Reformia; Hasimun, Patonah; Jafar, Garnadi; Putriyanti, Al-fira; Zakaria, Hasballah
Science Midwifery Vol 13 No 6 (2026): February: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i6.2212

Abstract

Introduction: Measuring vascular parameters using the NIVA (Non-Invasive Vascular Analyzer) is an important step in assessing the health of blood vessels in the community, especially in groups at risk of hypertension. Objective: This study aims to describe the results of baseline blood pressure and vascular parameter examinations in respondents before further intervention. Methods: Respondents underwent an initial screening process including informed consent, anamnesis, and baseline blood pressure measurement. Results: The graph shows a balanced gender distribution and a dominance of the 31-40 and 41-50 age groups, which are age groups at high risk of experiencing increased arterial stiffness. The hand and foot blood pressure graphs show variations in systolic and diastolic values ​​​​in the mild to moderate hypertension range, indicating that the hemodynamic condition of the respondents is stable and safe for NIVA examination. NIVA measurements were performed by attaching a cuff to the upper arm and left ankle to obtain parameters such as baPWV, ABI, MAP, PP, and Vascular Age. Blood pressure variations in the baseline graph support accurate reading of vascular parameters, especially because there was no indication of peripheral stenosis based on the comparison of hand and foot blood pressure. The data recording and validation process was performed by comparing the measurement results to the baseline, which was consistent with the initial graph. Conclusion: The examination results indicate that the respondents' initial condition met the requirements for non-invasive vascular evaluation and provided a representative picture of blood vessel health status prior to clinical intervention.
Co-Authors Afief, Arief R. Agus Sulaeman Agus Sulaeman Agus Sulaeman Almasih, Royan Aris Suhardiman Aulia Nurfazri Istiqomah Avianningsih, Reformia Choerunnisa , Fitriani Choirunnisa, Zulfy Dadang Juanda Dedep Nugraha Deny Puriyani Azhary Dewi, Nova Freena Dian Eka Fakhira Fatmawati, Eva Fenti Fatmawati Garnadi Jafar, Garnadi Hardianti, Mira Hendra Mahakam Putra Hendra Mahakam Putra Heni Lindasari Ika Kurnia Sukmawati Irma Yulianti Jajang Japar Sodik Lia Marliani Lindasari, Heni Lindasari, Heni Mamay M Sobandi Maulana, Mamay Maya Rosdiana Muzaki, Yoga Adi Restu Nova Freena Dewi Purwaniati, Purwaniati Putra, Hendra Mahakam Putra, Hendra Mahakam Putriyanti, Al-fira Rukmana, Aan Rukmana Sabarudin, Cecep Saputro, M. Ramadhan Sintia Veronika Purba Siti Nurjanah Siti Pandanwangi TW Sodik, Jajang Japar Solihah, Nurlaella Suhardiman, Aris Sukmawati, ika kurnia Sulaeman, Agus Sumarna, Rendi Supriyatni Kartadarma WAWAN KURNIAWAN Wempi Budiana Yani Mulyani Yani Mulyani Yanyan Mulyani Yuniarto, Ari Zahra, Nadhira Aulia Zakaria, Hasballah Zulfy Choirunnisa Zuniarto, Ahmad Azrul