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Aktivitas BSLT Fraksi Daun dan Gall Syzygium guineensis: Studi Komparatif Marliza, Hesti; De Nanda Herru, Yoan; Yelmiza, Yelmiza; Surya, Alfin
Journal of Research and Education Chemistry Vol. 7 No. 2 (2025): Oktober
Publisher : UIR Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25299/jrec.2025.vol7(2).25956

Abstract

This study investigates the Brine Shrimp Lethality Test (BSLT) activity of leaf and gall fractions of Syzygium guineensis, a plant known for its traditional medicinal properties. The objective is to evaluate the cytotoxic potential of these fractions using BSLT, which is a reliable method for assessing toxicity. Leaf and gall samples were extracted using n-hexane, ethyl acetate, and ethanol-water solvents. The cytotoxicity was quantified by determining the LC50 values for each fraction. The results indicated that the leaf fractions exhibited LC50 values of 29.45 ppm (n-hexane), 28.33 ppm (ethyl acetate), and 30.57 ppm (ethanol-water). For the gall fractions, the LC50 values were 27.80 ppm (n-hexane), 26.61 ppm (ethyl acetate), and 24.95 ppm (ethanol-water). All fractions demonstrated significant cytotoxic activity, categorizing them as highly toxic. This study highlights the potential of both leaf and gall fractions of Syzygium guineensis as sources of cytotoxic agents, warranting further investigation for therapeutic applications.  
Pengabdian Kepada Masyarakat Melalui 7 Langkah Mencuci Tangan Dengan Baik Dan Benar Kelurahan Galang Baru Kota Batam Sri Hainil; Suhaera Suhaera; Suci Fitriani Sammulia; Hesti Marliza; Nanda Siska; Sri Rahayu Melpa Sari
Jurnal Pengabdian Ilmu Kesehatan Vol. 1 No. 1 (2021): Maret: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v1i1.3591

Abstract

Washing your hands is one way to remove germs and to avoid disease transmission. The habit of Indonesian children in washing their hands is still in the low category. At school, children not only learn, but there are many other activities that children can do at school, such as playing, touching or exchanging things with friends. Hand washing must be taught to children from an early age so that children have the habit of washing their hands, so that children avoid disease. Standard recommendations for preventing the spread of infection are through washing hands regularly using soap and clean water, implementing coughing and sneezing etiquette, avoiding direct contact with livestock or wild animals and avoiding close contact with anyone showing symptoms of respiratory disease such as coughing and sneezing. Clean and Healthy Living Behavior (PHBS) is a set of behaviors that are practiced on a conscious basis as a result of learning that enables a person or family to help themselves in the field of health and play an active role in realizing public health. Healthy conditions can be achieved by changing unhealthy behavior to healthy behavior and creating a healthy environment in the household. Therefore, health needs to be maintained, maintained and improved by every member of the household and fought for by all parties. The introduction of Clean and Healthy Living Behavior (PHBS) in elementary school education is able to maintain, improve and protect the health of each household member from the threat of disease and an environment that is less conducive to healthy living. Washing your hands with soap can kill the virus that causes infection from your hands before the virus infects the body. Apart from that, washing your hands regularly can also reduce the spread of the virus to other people.
Pengabdian Kepada Masyarakat Melalui Edukasi Kesehatan Melalui Penyuluhan Vitamin Di Posyandu Flamboyan Kota Batam Hesti Marliza; Arie Vonikartika; Henny Rachdianti Tjahjono Suyarto; Nurlia Oktavianty
Jurnal Pengabdian Ilmu Kesehatan Vol. 1 No. 2 (2021): Juli: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v1i2.3593

Abstract

Vitamin A was the first fat-soluble vitamin to be discovered. This finding states that all retinoids and precursors/provitamin A/carotenoids have biological activity as retinol. Vitamin A plays an important role in children's growth and development. Vitamin A deficiency (KVA) increases the risk of developing infectious diseases such as diarrhea, pneumonia, pneumonia and even death. Another most serious consequence of vitamin A deficiency (KVA) is night blindness, which is another form of xeropthalmia such as damage to the cornea and blindness. Vitamin A can increase the body's resistance to infectious diseases such as measles, diarrhea and ARI and has a very important role in eye health.
AKTIVITAS ANTIJAMUR FRAKSI DAUN MANGKOKAN (Polyscias scutellaria) TERHADAP JAMUR TRICHOPHYTON RUBRUM Rury Trisa Utami; Sri Hainil; Hesti Marliza; Hafizah, Hafizah
Nusantara Hasana Journal Vol. 5 No. 10 (2026): Nusantara Hasana Journal, March 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i10.1922

Abstract

One of the natural ingredients that are often used as medicinal plants is mangkokan leaves (Polyscias scutellaria). Mangkokan leaves have the potential as an antifungal. Trichophyton rubrum is a fungus that infects human skin. The purpose of this study was to determine the antifungal activity of mangkokan leaf fractions (Polyscias scutellaria) against Trichophyton rubrum fungi. Fractionation was carried out using the liquid-liquid method using n-hexane, ethyl acetate and ethanol-water solvents. Testing was carried out using the disc paper diffusion method. The concentration of the fraction extract used was 600 µg/disk. The results showed that of the three fractions of mangkokan leaves (Polyscias scutellaria), the ethyl acetate fraction and the ethanol-water fraction had antifungal activity, while the n-hexane fraction did not have antifungal activity. Based on the research that has been done, it can be concluded that the fraction of mangkokan leaves (Polyscias scutellaria) has antifungal activity against Trichophyton rubrum fungus. Of the three fractions tested, the ethanol-water fraction has the highest antifungal activity with an average inhibition zone of 11.3 mm against Trichophyton rubrum fungus, the ethyl acetate fraction has an inhibition zone with an average of 4.5 mm while the n-hexane fraction has no inhibition zone. The three fractions have been compared with ketoconazole 30 µg/disk as a positive control and 10% DMSO as a negative control. From the comparison of fraction measurements against the positive control, the ethanol-water fraction is included in the strong category and the ethyl acetate fraction is included in the weak category.
IDENTIFIKASI BAHAN KIMIA OBAT SIBUTRAMIN HCl PADA JAMU PELANGSING YANG BEREDAR DI KOTA BATAM MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS Mayefis, Delladari; Marliza, Hesti; Fadhil, Muhammad
Jurnal Riset Kefarmasian Indonesia Vol. 7 No. 2 (2025): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v7i2.531

Abstract

Traditional medicine is a mixture of natural ingredients in the form of simplicia, animals, minerals, sarian or galenic. One form of traditional medicine is slimming herbal medicine. In slimming herbal medicine, medicinal chemicals are prohibited from being added to traditional medicine preparations because they harm health if used continuously. One of the medicinal chemicals that is often misused is sibutramine HCl. The aim of this research is to identify the chemical drug sibutramine HCl in slimming herbal medicine circulating in Batam City. The method used is a qualitative method using thin layer chromatography and a quantitative method using UV-Vis spectrophotometry. The ferrous phases used are ethyl acetate : n-Hexane (7:3), acetone : chloroform (7:3), acetone : chloroform : n-hexane (5:3:2) and the stationary phase used is GF254 silica gel plate . The results of qualitative identification of slimming herbal medicine circulating in Batam City showed that there was no chemical drug sibutramine HCl in each sample. Quantitative testing was not carried out because there were no samples that were positive for containing the chemical drug sibutramine HCl
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN SURUHAN (Peperomia pellucida L. Kunth) TERHADAP Propionibacterium acnes PENYEBAB JERAWAT Yufiradani, Yufiradani; Mayefis, Delladari; Marliza, Hesti
Jurnal Riset Kefarmasian Indonesia Vol. 2 No. 1 (2020): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v2i1.70

Abstract

Acne is one of the most common skin diseases that occur at all ages, especially in adolescents who are just experiencing puberty. One of the plants that has antibacterial properties is the leaves of suruhan. However untill now not found research of suruhan leaf used as an acne medicine. The aim of this study was to determine the antibacterial activity of suruhan leaf extracts on the growth of Propionibacterium acnes. The method used is disc diffusion by given 5 treatments starting with a concentration of 15%, 20%, 25%, positive control of clindamycin and negative control of aquadest.. The results obtained from leaf extracts were able to inhibit the growth of P. acnes bacteria in various concentrations. Suruhan leaf extracts at a concentration of 25% showed response resistance was greater than other concentrations. The one way Anova SPSS test showed p <0.05 which means that there were differences in the inhibitory concentration of various extracts on the growth of P. acnes that cause acne
PENINGKATAN KESEHATAN MASYARAKAT DAPUR 3 AIR NAGA MELALU SENAM SEHAT Rury Trisa Utamii; Ayu Amelia; Rastria Meilanda; Delladari Mayefis; Hesti Marliza; Eka Febriyanti
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 6 No. 2 (2025): Volume 6 No. 2 Tahun 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v6i2.42990

Abstract

Dapur 3 Air Naga adalah salah satu desa yang berada Di Kecamatan Sijantung, Sembulang Provinsi Kepulauan Riau. Mayoritas masyarakat desa dapur 3 Air Naga bekerja di pantai, Libur kerja pada hari minggu. Biasanyan masyarakat pada waktu libur kerja menggunakan waktu nya untuk beristirahat sehingga dapat dilihat bahwa permasalahan yang terdapat di desa belum maksimalnya untuk penggnan waktu pada saat di libur kerja. Dari hal tersebut perlu adanya sebuah kegiatan untuk meningkatkan kesehatan masyarakat sebagai salah satu solusi untuk dapat menggunakan waktu di libur kerja dengan bermanfaat selain istirahat dengan berolahraga yaitu senam bersama. Tujuan dari adanya kegiatan senam bersama ini agar masyarakat Desa dapur 3 Air Naga dapat meningkatkan kesehatan tubuh melalui senam bersama yang menyenangkan. Metode yang digunakan adalah memberitahu dan mengajak secara langsung masyarakat sekitar secara langsung. Metode yang digunakan pada saat senam adalah metode demonstrasi, gerakan senam akan dipimpin oleh mahasiswa KKN yang sesuai dengan bidang ahlinya
Analisis Proksimat Dan Skrining Fitokimia Tumbuhan Di Perairan Pantai Sekilak Kota Batam Hesti Marliza; Suci Fitriani Sammulia; Delladari Mayefis
The Journal General Health and Pharmaceutical Sciences Research Vol. 1 No. 2 (2023): June: The Journal General Health and Pharmaceutical Sciences Research
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/tjghpsr.v1i2.225

Abstract

Riau Islands is one of the provinces in Indonesia that has abundant biodiversity. Biodiversity is the basis of various treatments and industrial discoveries in the pharmaceutical field in the future, people especially in developing countries depen on plants as medical ingredients to maintain their health. Therefore, efforts are needed to determine the content of primary and secondary metabolites obtained through proximate analysis and phytochemical screening test in plants. This study aims to explore and document the content of plant compounds on the Sekilak beach, Batam City. Amphiroa fragilissima was positive contained flavonoids, steroids, and saponins, water content 36,31%, ash content 44,09%, protein content 3,21%, fat content 8% and carbohydrate content 8,39%. Halimeda opuntia positive contained flavonoids compunds, alkaloids, and water content 27,68%, ash content 33,70%, fat content 7%, protein content 0,25%, and carbohydrate contain 31,37%. Halimeda macroloba positive contains flavonoids compounds, steroids, saponins, and water content 53,17%, ash content 13,26%, fat content 6%, protein content 1,00%, and carbohydrate content 26,57%.
Co-Authors Adella Adella Alfin Surya Alfin Surya Alfin Surya alfin_surya Alvira Rahma Fissilmi Amelia, Ayu Andre Ajis Saputra Anggi Wulandari Aprilya Sri Rachmayanti Apriyani Efendi Arie Vonikartika Arie Vonikartika Arini, Larasuci Ayu Amelia Cindy Octavia Delladari Mayefis Delladari Mayefis Delladari Mayefis Delladari Mayefis Delladari Mayefis Delladari Mayefis Desy Maniarti Gusmali Diani Mega Sari Didi Yunaspi Dimas Prada Sumitra Dita Oktaviani Eka Febriyanti Elfasyari, Trie Yuni Eliya Mursyida Fadillah, Ainun Faziyana Fenida, Rizka Fitri Harlina Sagala Fitri Nadira Fitri Ramadhani Ghiffari, Habibie Deswilyaz Gusmali, Desy Maniarti Hafizah Hafizah Haqqelni Nur Rosyidah Hasan, Nahrul Hayat, Nahrul Henny Rachdianti Tjahjono Suyarto Henny Rachdianti Tjahjono Suyarto Henny Rachdiati Maharani, Refina Maria Yunivista Mawardi Badar Mawardi Badar Mayefis, Delladari Muhammad Fadhil Nahrul Hayat Nanda Siska Nanda Siska Nurlia Oktavianty Nurlia Oktavianty Nurliyasman Nurliyasman Nurliyasman Nurliyasman Pratiwi Oktavia Pratiwi, Reri Qoirina Raihani Islamiati Rastria Meilanda Rastria Meilanda RENY HARYANI Reny Haryani Rizka Fenida Rury Trisa Utami Rury Trisa Utami Rury Trisa Utamii Sammulia, Suci Fitriani Sarina Sembiring Milala Siahaan, Anggel Erggita Siska, Dedi Sri Hainil Sri Hainil Sri Hainil Sri Hainil Sri Hainil, Sri Sri Rahayu Melpa Sari Sri Rahayu Melpa Sari Suci Fitriani Sammulia Suci Fitriani Sammulia Suci Fitriani Sammulia Suhaera Suhaera Suhaera Suhaera Suhaera Suhaera T. Eltrikanawati Trinur Atika Saputri Utami, Rury Trisa Veranica Lestari Yelmiza Yoan De Nanda Herru Yufiradani, Yufiradani Yuliyana Yuliyana Yunisa Friscia Yusri Yunisa Friscia Yusri Zaiyar Zaiyar zaiyar Zaiyar, Zaiyar