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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Biologi Tropis Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Jurnal Respirasi (JR) UMI Medical Journal PREPOTIF : Jurnal Kesehatan Masyarakat Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Jurnal Kesehatan Kusuma Husada Jurnal Sehat Indonesia (JUSINDO) International Journal of Health Science and Technology WAL'AFIAT HOSPITAL JOURNAL
Sodiqah, Yani
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : International Journal of Health Science and Technology

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The potential of bilimbi leaf (Averrhoa bilimbi L.) extract as an inhibitor of Staphylococcus epidermidis growth Asnur, Andi Muhammad Nawwar; Waspodo, Nurelly N; Irwan, Andi Alamanda; Sodiqah, Yani; Mangarengi, Yusriani
International Journal of Health Science and Technology Vol. 6 No. 3 (2025): April
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v6i3.3965

Abstract

Coagulase-negative staphylococci (CoNS) are part of the normal skin flora and are often considered to be minimally pathogenic or even non-pathogenic. However, in certain cases, CoNS bacteria can lead to increased morbidity and mortality, particularly in high-risk patients. This study aims to examine the inhibition zones of Staphylococcus epidermidis following treatment with bilimbi (Averrhoa bilimbi L.) leaf extract at concentrations of 50%, 75%, and 100%, and to compare the inhibition zones across these three concentrations. This research employed a laboratory experimental design using the Kirby-Bauer disc diffusion method. The results showed that the inhibition zones for Staphylococcus epidermidis treated with 50% extract concentration were 12.78 mm, 13.01 mm, and 13.10 mm, classified as intermediate. At a 75% concentration, the inhibition zones were 13.07 mm, 13.40 mm, and 15.12 mm, ranging from intermediate to sensitive. Meanwhile, the 100% concentration produced inhibition zones of 15.64 mm, 16.89 mm, and 17.1 mm, classified as sensitive. A comparative analysis of the inhibition zones indicated that the 100% concentration produced the largest zone of inhibition among the three concentrations tested.
Potential of Soursop Leaf Extract (Annona Muricata L.) as an Antimicrobial Against Staphylococcus epidermidis Fauziy, Aqil; Waspodo, Nurelly N.; Irwan, Andi Alamanda; Sodiqah, Yani; Karina, Dhian; Harahap, Muhammad Wirawan
International Journal of Health Science and Technology Vol. 7 No. 1 (2025): Juli
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v7i1.3966

Abstract

Staphylococcus epidermidis is an opportunistic bacterium that can cause infections, particularly in individuals with weakened immune systems. The increasing resistance to antibiotics has encouraged the use of medicinal plants such as soursop leaves (Annona muricata L.), which contain antibacterial compounds. This study aims to evaluate the antibacterial effectiveness of soursop leaf extract against the growth of Staphylococcus epidermidis at concentrations of 50%, 75%, and 100%. The study specifically investigated the inhibition zones formed at each concentration (50%, 75%, and 100%) of Annona muricata L. extract against Staphylococcus epidermidis, and compared the antibacterial activity across these three concentrations. This research used a laboratory experimental design with the Kirby-Bauer disc diffusion method to assess the antibacterial activity. The extract was prepared using 96% ethanol and tested at the concentrations stated. Gentamicin 10 μg was used as a positive control, while sterile distilled water served as the negative control. The inhibition zones were observed after 24 hours of incubation at 37°C. The results showed that soursop leaf extract at 50% and 75% concentrations produced inhibition zones categorized as resistant. At 100% concentration, the inhibition zone ranges from resistant to intermediate. The comparison across all three concentrations indicates that the 100% concentration demonstrated notable antimicrobial activity against Staphylococcus epidermidis.
Co-Authors Ahmad, Izhar Fitrah Aisyah, Windy Nurul Akib, Marlyanti Nur Rahmah Alyaa Zatira, Difa Amaliah M, A. Alya Amrizal Muchtar Andi Sitti Fahirah Arsal Anggita, Dwi Aprilani Hattah, Dhian Karina Ardhani, Ahmad Arfah, Arni Isnaini Ashilah Asrijaya, Andi Audya Asnur, Andi Muhammad Nawwar Aulia, Aulia Baba, Firda Bakhtiar, Ilma Khaerani Amaliyah Basri, Rezky Pratiwi Lambang Beru Gani, Azis diana, Nur akhsan Fattah, Nurfachanti Fauziy, Aqil Halim, Aqisha Nuramini Harahap, Muhammad Wirawan Hasbi, Berry Erida Hastiah, Hastiah Hatta, Dhian Karina Irwan, Andi Alamanda Karim, Marzelina Karina, Dhian M, A Alya Amaliah Maharani, Ratih Natasha Mangarengi, Yusriani Mochtar, Shulhana Mokhtar, Shulhana Nurelly, Nurelly Nurhikmawati, Nurhikmawati Nurmadilla, Nesyana Rahmah Akib, Marliyanti Nur Sabir, Nurani Islami Sam, Andi Dhedie Prasatia Sri Wahyu Surdam, Zulfiyah Taufan, Wa Ode Sri Apriani Waspodo, Nurelly N Waspodo, Nurelly N. Wiriansya, Edward Pandu Wulandari, Mustika Yanti, Andi Kartini Eka Z., Nurul Islah Zulfahmidah, Zulfahmidah