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All Journal Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Biologi Tropis JURNAL PENDIDIKAN TAMBUSAI Jurnal Ilmu Kedokteran dan Kesehatan Poltekita : Jurnal Ilmu Kesehatan Health and Medical Journal PREPOTIF : Jurnal Kesehatan Masyarakat Borneo Journal of Medical Laboratory Technology Jurnal Kesehatan Tambusai JOURNAL LA MEDIHEALTICO Wal'afiat Hospital Journal INDONESIAN JOURNAL OF HEALTH Journal of Community Health Provision Innovative: Journal Of Social Science Research WAL'AFIAT HOSPITAL JOURNAL Jurnal Balireso: Jurnal Pengabdian pada Masyarakat
Abdi, Dian Amelia
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Evaluation of the Clinical Picture and Effectiveness of Antifungal Therapy in Tinea Corporis Cases in Tropical Areas: Literature Review Abduh, Anniza Putri; Abdi, Dian Amelia; Setiawati, Solehca
Journal of Community Health Provision Vol. 6 No. 1 (2026): Journal of Community Health Provision
Publisher : PSPP JOURNALS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55885/jchp.v6i1.856

Abstract

Tinea corporis is a superficial dermatophyte infection of the skin commonly found in tropical regions due to hot and humid environmental conditions. This disease is characterized by well-defined, scaly, annular lesions accompanied by pruritus, and is influenced by various risk factors such as age, gender, personal hygiene, and comorbidities. Various topical and systemic antifungal therapies have been used in the treatment of tinea corporis, but their effectiveness can vary depending on the clinical presentation and patient characteristics. This study is a literature review conducted by reviewing research articles related to the clinical presentation and effectiveness of antifungal therapy in cases of tinea corporis in tropical regions. The literature search was conducted through Google Scholar, PubMed, ResearchGate, Elsevier, and NCBI databases. A total of 10 articles published between 2021 and 2025 that met the inclusion criteria were analyzed descriptively and synthesized narratively. The review indicates that Trichophyton rubrum is the most common cause of tinea corporis. Topical antifungal therapy is effective in mild to moderate cases, while systemic therapies such as itraconazole, terbinafine, and griseofulvin are more effective in extensive, chronic, or resistant cases. The combination of topical and systemic therapy shows a higher cure rate and reduces recurrence rates. The clinical presentation and response to therapy for tinea corporis in tropical regions are influenced by environmental factors, patient characteristics, and the choice of antifungal regimen. Appropriate clinical evaluation and rational use of antifungal therapy, both topical and systemic, are crucial for achieving optimal cure and preventing recurrence.
The Role of Malassezia Spp. in Pityrasis Versicolor: A Literature Review Umar, Zahlah Levia Redini; Abdi, Dian Amelia; Zainuddin, A. Sastri; Waspodo, Nurelly Noro; Adharia, Adharia
Journal of Community Health Provision Vol. 6 No. 1 (2026): Journal of Community Health Provision
Publisher : PSPP JOURNALS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55885/jchp.v6i1.876

Abstract

Pityriasis versicolor (PV) is a skin disease caused by the fungus Malassezia, common in tropical regions with high humidity, such as Indonesia. Pityriasis versicolor is characterized by hypopigmented or hyperpigmented patches, primarily on the chest, back, neck, and face, with some cases accompanied by itching. Risk factors include oily skin, immune conditions, genetics, and hot and humid environments. Further research is needed to understand the role of Malassezia in Pityriasis versicolor to improve treatment and prevent recurrence. To determine the role of Malassezia spp. in Pityriasis versicolor (PV) based on a literature review. Literature review with a narrative review design. Based on several reviewed journals, it can be concluded that Malassezia spp., which are part of the normal skin microbiota, can become pathogenic in individuals with certain predisposing factors. The transformation from yeast to hyphae, as well as the production of virulence factors such as lipase, protease, phospholipase, azelaic acid, melanin-like pigments, and the ability to form biofilms, play a role in the development of Pityriasis versicolor lesions. Interaction with the host occurs through direct mechanisms (irritant metabolites, keratinase) and immunological mechanisms (activation of inflammatory and allergic pathways), leading to skin barrier disruption, pigmentation changes, fine scaling, and potential alopecia. Variation in species and virulence profiles contributes to differences in clinical manifestations and responses to antifungal therapy. Malassezia spp. plays a key role in the development of Pityriasis versicolor through multifactorial virulence mechanisms and interactions with host predisposing factors, which influence clinical manifestations and treatment outcomes.
Karakteristik Pasien Morbus Hansen di Rumah Sakit Ibnu Sina Makassar dan Puskesmas Jejaring Tahun 2022-2024 Al Ansar, Nur Maeymanah; Waspodo, Nurelly Noro; Pramono, Sigit Dwi; Vitayani , Sri Vitayani; Abdi, Dian Amelia
Health and Medical Journal Vol. 8 No. 2 (2026): HEME May 2026
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v8i2.2251

Abstract

Latar Belakang: Morbus Hansen (kusta) merupakan penyakit infeksi kronis yang disebabkan oleh Mycobacterium leprae dan masih menjadi masalah kesehatan masyarakat di Indonesia, dengan Indonesia menempati peringkat ketiga dunia dalam jumlah kasus baru. Pemahaman mengenai karakteristik pasien kusta menjadi fondasi penting untuk memperkuat strategi pengendalian dan meningkatkan mutu layanan kesehatan. Tujuan: Penelitian ini bertujuan untuk mengetahui gambaran karakteristik pasien Morbus Hansen di Rumah Sakit Ibnu Sina Makassar dan puskesmas jejaringnya periode 2022-2024 berdasarkan usia, jenis kelamin, pekerjaan, riwayat pendidikan, gejala awal, hasil pemeriksaan BTA, klasifikasi penyakit, jenis pengobatan, dan kepatuhan pengobatan. Metode: Penelitian ini merupakan studi deskriptif dengan pendekatan cross-sectional menggunakan data sekunder dari rekam medis pasien Morbus Hansen periode 2022-2024. Teknik pengambilan sampel menggunakan multistage sampling (tahap 1: pemilihan lokasi penelitian; tahap 2: total sampling seluruh rekam medis yang memenuhi kriteria inklusi). Seluruh data rekam medis pasien dengan diagnosis definitif dan data lengkap diikutsertakan dalam penelitian. Data dianalisis secara univariat dengan menyajikan distribusi frekuensi dan persentase. Hasil: Dari 73 pasien, sebagian besar mendapatkan pelayanan di puskesmas (90,4%) dengan proporsi tertinggi di Puskesmas Tamalate (19,2%). Pasien didominasi usia dewasa 18-59 tahun (71,2%), laki-laki (64,4%), pekerja buruh (24,7%), dan pendidikan SMA (30,1%). Gejala awal terbanyak adalah kelainan kulit disertai mati rasa (75,3%), dengan hasil BTA positif (72,6%) dan klasifikasi tipe Multibasiler (72,6%). Pengobatan MDT MB diberikan kepada 72,6% pasien, dan 67,1% pasien patuh menjalani pengobatan. Kesimpulan: Karakteristik pasien Morbus Hansen di lokasi penelitian didominasi usia produktif, laki-laki, pekerja buruh, dengan gejala klasik bercak mati rasa, serta tingginya proporsi tipe MB dan BTA positif yang mengindikasikan masih terjadinya keterlambatan diagnosis. Masih ditemukan sepertiga pasien (32,9%) dengan ketidakpatuhan pengobatan yang memerlukan intervensi program.
Karakteristik Pasien Systemic Lupus Erythematosus di Rumah Sakit Ibnu Sina Makassar 2020–2023 Anugrah, Muh. Arya; Nasaruddin, Hermiaty; Gayatri, Sri Wahyuni; Abdi, Dian Amelia; Yunita, Lisa
Borneo Journal of Medical Laboratory Technology Vol. 8 No. 2 (2026): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v8i2.12388

Abstract

Systemic Lupus Erythematosus (SLE) merupakan penyakit autoimun kronis dengan manifestasi klinis dan komplikasi yang beragam, sehingga pemetaan karakteristik pasien diperlukan untuk mendukung deteksi dini dan penatalaksanaan. Penelitian ini bertujuan mengetahui karakteristik pasien SLE di Rumah Sakit Ibnu Sina YW-UMI Makassar periode 2020–2023. Penelitian menggunakan desain deskriptif dengan data sekunder rekam medis dan teknik total sampling. Sampel penelitian berjumlah 18 pasien yang memenuhi kriteria. Variabel yang dianalisis meliputi jenis kelamin, usia, manifestasi klinis, komplikasi, riwayat terapi, dan riwayat keluarga SLE. Hasil penelitian menunjukkan seluruh pasien berjenis kelamin perempuan (100,00%); kelompok usia terbanyak >40 tahun (66,66%); manifestasi klinis tersering adalah muskuloskeletal (50,0%); komplikasi tersering adalah nefritis lupus (27,77%); terapi yang paling banyak digunakan adalah kombinasi imunosupresan dan kortikosteroid (55,56%); dan mayoritas pasien tidak memiliki riwayat keluarga SLE (66,66%). Disimpulkan bahwa pasien SLE pada periode penelitian didominasi perempuan usia >40 tahun dengan manifestasi muskuloskeletal, komplikasi nefritis lupus, serta penggunaan terapi kombinasi imunosupresan-kortikosteroid.
Co-Authors Abduh, Anniza Putri Adharia, Adharia Al Ansar, Nur Maeymanah Alif, Zahra Rindu Tsabitha Ameliah, Nabila Anastasia, Rizka Angraeni, Andi Gita Sentini Anugrah, Muh. Arya Arfah, Arni Isnaini Arifin, Arina Fathiyyah Azis, Fenny Octaviani Bahmary, Aryanti Darariani Iskandar Dewi, Anna Sari Erwin, Mochammad Gayatri, Sri Wahyuni Hamriani, Indah Harahap, Muhammad Wirawan Harun, Achmad Ilyas, Atiqah Muthmainnah Imran Safei, Imran Irwan, Andi Alamanda K, Indah Lestari Daeng L Basri, Resky Pratiwi Latief, Rachmat M, Rasmah M. Yogi Riyantama Isjoni Mangarengi, Yusriani Marfia, Marfia Maulani, Destya Mokhtar, Shulhana Muhtar, Muftiar Mulyadi, Farah Ekawati Mutmainnah Mutmainnah Nasaruddin, Hermiaty Ningsi, Iin Widya NUR FADILAH Nurelly Noro Waspodo, Nurelly Noro Nurelly Waspodo Nurelly, Nurelly Nurfadillah, Siti Nurmadilla, Nesyana Pramono, Sigit Dwi Purnamasari, Reeny Putri, Andi Nur Afifah Maharani Qarinah, Maryam Rahmasari, Halisa Rasfayanah, Rasfayanah Razak, Kaisar Roem, Nurul Rumila Rusnaedi, Adinda Nurqalbi Safitri, Asrini Setiawati, Solehca Sri Vitayani Surdam, Zulfiyah Susanti, Maya Umar, Zahlah Levia Redini Utami, Asia Artha Vitayani , Sri Vitayani W, Nurelly Wahab, Iswan Wana, Nirwana Waspodo, Nurelly N. Wiriansya, Edward Pandu Yanti, Andi Kartini Eka Yuniati, Lisa Yuniaty, Lisa Yunita, Lisa Zainuddin, A. Sastri