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Evaluation of the Clinical Picture and Effectiveness of Antifungal Therapy in Tinea Corporis Cases in Tropical Areas: Literature Review Abduh, Anniza Putri; Abdi, Dian Amelia; Setiawati, Solehca
Journal of Community Health Provision Vol. 6 No. 1 (2026): Journal of Community Health Provision
Publisher : PSPP JOURNALS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55885/jchp.v6i1.856

Abstract

Tinea corporis is a superficial dermatophyte infection of the skin commonly found in tropical regions due to hot and humid environmental conditions. This disease is characterized by well-defined, scaly, annular lesions accompanied by pruritus, and is influenced by various risk factors such as age, gender, personal hygiene, and comorbidities. Various topical and systemic antifungal therapies have been used in the treatment of tinea corporis, but their effectiveness can vary depending on the clinical presentation and patient characteristics. This study is a literature review conducted by reviewing research articles related to the clinical presentation and effectiveness of antifungal therapy in cases of tinea corporis in tropical regions. The literature search was conducted through Google Scholar, PubMed, ResearchGate, Elsevier, and NCBI databases. A total of 10 articles published between 2021 and 2025 that met the inclusion criteria were analyzed descriptively and synthesized narratively. The review indicates that Trichophyton rubrum is the most common cause of tinea corporis. Topical antifungal therapy is effective in mild to moderate cases, while systemic therapies such as itraconazole, terbinafine, and griseofulvin are more effective in extensive, chronic, or resistant cases. The combination of topical and systemic therapy shows a higher cure rate and reduces recurrence rates. The clinical presentation and response to therapy for tinea corporis in tropical regions are influenced by environmental factors, patient characteristics, and the choice of antifungal regimen. Appropriate clinical evaluation and rational use of antifungal therapy, both topical and systemic, are crucial for achieving optimal cure and preventing recurrence.
The Role of Malassezia Spp. in Pityrasis Versicolor: A Literature Review Umar, Zahlah Levia Redini; Abdi, Dian Amelia; Zainuddin, A. Sastri; Waspodo, Nurelly Noro; Adharia, Adharia
Journal of Community Health Provision Vol. 6 No. 1 (2026): Journal of Community Health Provision
Publisher : PSPP JOURNALS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55885/jchp.v6i1.876

Abstract

Pityriasis versicolor (PV) is a skin disease caused by the fungus Malassezia, common in tropical regions with high humidity, such as Indonesia. Pityriasis versicolor is characterized by hypopigmented or hyperpigmented patches, primarily on the chest, back, neck, and face, with some cases accompanied by itching. Risk factors include oily skin, immune conditions, genetics, and hot and humid environments. Further research is needed to understand the role of Malassezia in Pityriasis versicolor to improve treatment and prevent recurrence. To determine the role of Malassezia spp. in Pityriasis versicolor (PV) based on a literature review. Literature review with a narrative review design. Based on several reviewed journals, it can be concluded that Malassezia spp., which are part of the normal skin microbiota, can become pathogenic in individuals with certain predisposing factors. The transformation from yeast to hyphae, as well as the production of virulence factors such as lipase, protease, phospholipase, azelaic acid, melanin-like pigments, and the ability to form biofilms, play a role in the development of Pityriasis versicolor lesions. Interaction with the host occurs through direct mechanisms (irritant metabolites, keratinase) and immunological mechanisms (activation of inflammatory and allergic pathways), leading to skin barrier disruption, pigmentation changes, fine scaling, and potential alopecia. Variation in species and virulence profiles contributes to differences in clinical manifestations and responses to antifungal therapy. Malassezia spp. plays a key role in the development of Pityriasis versicolor through multifactorial virulence mechanisms and interactions with host predisposing factors, which influence clinical manifestations and treatment outcomes.