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All Journal Medula Jurnal Farmasi Klinik Indonesia Acta Pharmaceutica Indonesia Pharmascience JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JFL : Jurnal Farmasi Lampung Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Majalah Farmasetika JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Kesehatan Tambusai Jurnal Buana Farma Jurnal Jaminan Kesehatan Nasional Sains Medisina Jurnal Farmasi SYIFA Medic Nutricia : Jurnal Ilmu Kesehatan Jurnal Riset Ilmu Kesehatan Umum dan Farmasi JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Suri, Nurma
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Journal : JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA

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A Comprehensive Evaluation of Antibiotic Usage: Establishing a Foundation for Effective Antimicrobial Stewardship Suri, Nurma; Junando, Mirza; Afriyana, Regi
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 11 No. 3 (2024): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v11i32024.298-311

Abstract

Background: The intensive care unit (ICU) is a significant area of antibiotic use, accounting for a substantial proportion of the overall antibiotic consumption. The inappropriate use of antibiotics in such settings has a notable impact on the emergence of antimicrobial resistance. Objective: This study evaluated the rationality of antibiotic use in the ICU of RSUD Abdul Moeloek Hospital in Lampung Province. Methods: This study was conducted between December 2022 and February 2023 using a prospective method and purposive sampling. An evaluation was conducted using the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) system for quantitative analysis and Gyssens criteria for qualitative assessment. The research subjects comprised 55 individuals, the majority of whom were male (58.2%), aged > 65 years (29.1%), remained in the ICU for less than seven days (78.2%), and subsequently continued their treatment in a non-ICU (69.1%). Results: Quantitative analysis demonstrated that the total number of antibiotics administered in this study was 394.83 DDD, with a DDD/100 patient-day value of 113.78. Ceftriaxone was the most frequently prescribed antibiotic (219 DDD), whereas gentamicin was the least frequently prescribed (1 DDD). Qualitative analysis revealed that 17.6% of the patients exhibited irrational antibiotic use. Conclusion: Irrational use of antibiotics was observed in the following categories: IV A (1.1%); IV D (2.2%); III A (2.2%); III B (2.2%) IIA, (3.3%); IIB (5.5%); and I (1.1%). The study concluded that there was still a considerable degree of irrational antibiotic use.
Co-Authors Abda Abda Afriyana, Regi Afriyani, Afriyani Al Rasyid, Muhammad Irfan Ambarwati, Endah Andrifianie, Femmy Antika Sintia, Nova Asep Sukohar Asep Sukohar Asti, Windi Athallah, Muhammad Muzhafar Atri Sri Ulandari Aufa Nurrohmah, Anna Aulia Ramdini, Dwi Axcellia Theresa Ayu SWP, Fadillah Cathartica, Allamanda Cheri F. A. Dera Chintia Dwi Tanasa Ciptaningrum, Sekar Rahmasari Ratna Citra Yuliyanda Pardilawati Damayanti, Ervina Dedy Miswar Devvy Wahyu Mulyaningsih Diva Meylia Dwi Melani Dwi, Farah Faliha, Raisati Hikmah Farhana, Lubna Farras Qanitah Rony Febriana, Triana Ihsanti Dwi Rahayu Junando, Mirza Kirana, Shela Sandra Kylalona, Gracylia Lilik Koernia Wahidah Mallarangeng, Andi Nafisah Tendri Adjeng Mega Intan Yulianti Meiliana, Made Laksmi Mirza Junando Muhammad Fitra Wardhana Sayoeti Muhammad Iqbal Muhammad Maulana Nawawi, As’ari Niken Dwi Astarina Oktafany Oktafany Oktafany Oktafany, Oktafany Oktarlina, Resmi Zakiah Oktoba, Zulpakor Pardilawati, Citra Yuliyanda Pius Ave Rafael Silalahi Prabamukti, Ilyas Primadiamanti, Annisa Putri, Oka Mahila Gustia Rahmadhita, Elmira Rahman, M. Bobby Ramadhina, Farrasyifa Ramdini, Dwi Aulia Rasmi Zakiah Oktarlina Ratih Anggun Komalasari Risanti, Yumna Dwi Rizki Nisfi Ramdhini Rony, Farras Qanitah Roviq Umam S Sabrina, Dewi Salsabila, Lyansaputri Salsabilla, Kharisma Saputri, Gusti Ayu Rai Sarnianto, Prih Suryadi Islami Syahputri, Devina Harti Tiara Aninditha Triyandi, Ramadhan Vanadis, Zifa Aisha Wardhana, Muhammad Fitra Widodo, Alya Rahmah Widodo, Subur Wirasutisna, Komar Ruslan Yati Sumiyati, Yati Yuli Wahyu Tri Mulyani Yulianti, Mega Intan